$509 Cheap Flights from Panama to Brussels
One-way
Departing from
Panama
Going to
Brussels, Belgium
Brussels (BRU)
Belgium • October, 2026
89% AI deal score
$1,375 $745
Brussels (BRU)
Belgium • December, 2025
77% AI deal score
$910 $572
Brussels (BRU)
Belgium • November, 2026
75% AI deal score
$1,375 $509
Top Cheap Flight Deals from Panama to Brussels
Recent round-trip flight deals to Brussels
Sat, Apr 11 - Sat, May 9
Cheapest
Panama (PTY) - Brussels (BRU)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
Brussels (BRU) - Panama (PTY)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
$1,750
$780
-$970
55%
Mon, Feb 9 - Sun, Feb 15
Panama (PTY) - Brussels (BRU)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
Brussels (BRU) - Panama (PTY)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
$910
$777
-$133
15%
Mon, Jan 26 - Tue, Feb 3
Panama (PTY) - Brussels (BRU)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
Brussels (BRU) - Panama (PTY)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
$910
$777
-$133
15%
Mon, Apr 6 - Mon, Apr 27
Panama (PTY) - Brussels (BRU)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
Brussels (BRU) - Panama (PTY)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
$1,750
$794
-$956
55%
Sat, Apr 11 - Sat, May 9
Panama (PTY) - Brussels (BRU)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
Brussels (BRU) - Panama (PTY)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
$1,750
$792
-$958
55%
Mon, May 18 - Mon, Jun 8
Panama (PTY) - Brussels (BRU)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
Brussels (BRU) - Panama (PTY)
Turkish Airlines airlines • 1 stop • Istanbul (IST)
$1,750
$816
-$934
53%
The cheapest time to fly to Brussels
Ready to jet to Brussels on a budget? Check out these popular routes with surprisingly cheap fares (one-way prices):
Last-Minute Flights from Panama to Brussels
Need to get to Brussels ASAP? Even if you're booking a flight on short notice, there are often last-minute deals available:
Next 2 weeks deals
Last Minute Flight Deals!
We found last-minute flight deals to Brussels starting at $1324, departing in the next two weeks.
⌛ Last-Minute
David, Chiriquí - BRU
A great last-minute steal for a cross-country flight.
Found 5 days ago
$2113
round-trip
Facts About Flights from Panama to Brussels
To help you plan your journey, here are some quick Brussels flight facts and tips.
Brussels city airports
Brussels boasts a trio of airports serving different travel needs and preferences. Brussels Airport (BRU), the primary international gateway, offers a wide array of global connections and is known for its comprehensive facilities. Brussels South Charleroi Airport (CRL), favored by budget airlines, provides access to numerous European destinations at competitive prices. For regional travel, Antwerp International Airport (ANR) offers a more intimate and efficient experience, focusing on select European routes. Each airport presents distinct advantages depending on your itinerary and budget.
Brussels (BRU)
Brussels, Belgium
Brussels South Charleroi (CRL)
Brussels, Belgium
Antwerp International (ANR)
Brussels, Belgium
Pro tip: search “Brussels (Any)” to see fares to all Brussels airports – sometimes one is cheaper than the others on your dates.
Insights for flights to Brussels
Cheapest airport
Brussels South Charleroi Airport (CRL)
Looking for the ultimate budget-friendly Brussels access? Fly into Brussels South Charleroi Airport (CRL), known for hosting many low-cost carriers, including Ryanair and Wizz Air. Though it's a bit outside of central Brussels, stellar bus connections whisk you into the city. Don't let the name fool you – it's all about saving those euros for Belgian waffles!
Nonstop vs. 1-stop
50+ cities
Brussels Airport is a major hub connecting Europe, Africa, and North America, offering popular routes to cities like Barcelona, Rome, and New York.
Number of airlines
50+ airlines
Hold on to your hats, because Brussels is served by over 50 airlines, offering a wealth of options for your travels! Popular choices include flag carrier Brussels Airlines, budget-friendly Ryanair, and the Dutch giant KLM.
BRU Airport Deal Stats
Current most discounted routes
Avg. most discounted routes (last 3 months)
BRU airport insights
Best days to catch a deal
Wed, Tue
Based on the data, Tuesday and Wednesday have the highest counts of cheapest flight deals for Brussels airport. Therefore, you're most likely to find a deal on these days.
Avg. deal survival time
17.8 hours
Deals from Brussels airport typically last around 17.8 hours. This means that finding and booking quickly is essential to securing the best prices.
Rare deal frequency
12 deals
We found 12 rare deals for flights departing from Brussels in the past month. These rare deals, which usually consist of mistake fares, special promotions or ultra-discounts, received an AI Deal Score of 90+.
Average price drop
-72%
Travelers can save big on flights to Brussels, as the average price drop is a significant 71.8%. Keep an eye on fares to Brussels Airport (BRU) to take advantage of potential savings.
Next 4 weeks: deal forecast
Brussels Flight Forecast (Next Month)
Based on current trends, flight prices to Brussels are expected to remain stable for the next month. There might be a slight decrease in prices during the second week of January due to lower travel demand after the holiday season.
Top 5 biggest price drops (last 3 months)
Found on December 21
Debrecen - BRU
$1,060 → $122
88%
Found on December 24
Monastir - BRU
$2,275 → $291
87%
Found on December 19
Luxor - BRU
$690 → $94
86%
Found on December 17
Hanoi - BRU
$1,970 → $340
83%
Found on December 18
Ioannina - BRU
$700 → $135
81%
Check these nearby airports too
Looking for more options? These airports near BRU sometimes drop rare deals too:
Cologne Bonn Airport (CGN)
~14 rare deals/month
Düsseldorf International Airport (DUS)
~11 rare deals/month
Eindhoven (EIN)
~13 rare deals/month
If you’re flexible with departure cities, it’s worth keeping an eye on nearby airports — especially CGN and DUS for long-haul deal surprises.
When Is the Best Time to Fly from Panama to Brussels
Timing is everything when hunting for cheap flights. Here are data-backed insights on the best times to fly to Brussels:
Cheapest month
November
Cheapest month
The cheapest month to fly to Brussels is November. During this time, the city sees fewer tourists, resulting in lower airfare and accommodation costs. Plus, you can enjoy Brussels' cozy atmosphere and indulge in Belgian chocolates without the summer crowds.
Best day to book
Tuesday
Best day to book
The best day to book a flight to Brussels is typically Tuesday. Airlines often release deals early in the week to fill seats. Keep an eye on flash sales and limited-time offers that can pop up mid-week.
Cheapest days to fly
Wednesday
Cheapest days to fly
The cheapest days to fly to Brussels are usually mid-week, particularly Wednesday. Many travelers prefer weekend departures, causing prices to surge on Fridays and Saturdays. Opting for a Wednesday flight can save you a significant amount of money.
Advance booking sweet spot
2 months
Advance booking sweet spot
The advance booking sweet spot for flights to Brussels is around 2 months before your travel date. Booking within this window often strikes a balance between availability and price. Waiting too long might lead to higher fares as seats fill up.
Seasonal considerations
Brussels Airports & Ground Transportation
One big question for travelers is which Brussels airport to fly into. Here’s a quick guide to Brussels’s airports and how to get to the city from each:
Brussels Airport (BRU)
Brussels Airport (BRU) is the main international airport serving Brussels. Just a short ride from the city center, BRU offers a wide array of amenities, including shops, restaurants, and lounges to relax before your flight. Getting to Brussels is a breeze with direct train connections taking you right into the heart of the city. Taxis and buses are also readily available. Keep an eye out for delicious Belgian chocolates as you make your way through the terminal!
Tip: Arrive early to indulge in some last-minute Belgian chocolates!
Brussels South Charleroi Airport (CRL)
Brussels South Charleroi Airport (CRL), while a bit further from Brussels than BRU, it is well-connected and is a popular choice for budget travelers. CRL offers several shops and restaurants. To get to Brussels city center, you can hop on a direct bus which takes about an hour. Alternatively, a train connection is available from Charleroi-Sud railway station, accessible by bus from the airport. Be sure to factor in the extra travel time when heading to Brussels!
What to Do in Brussels
Brussels isn’t just about getting there – it’s about enjoying the country once you arrive! Here are some top things to do in Brussels, organized by interest:
Sightseeing & landmarks
Brussels is a city brimming with iconic landmarks! Be sure to visit the Grand Place, a stunning central square, and the Atomium, a unique structure offering panoramic views. Don't forget to snap a selfie with the Manneken Pis!
Arts & culture
Immerse yourself in Brussels' vibrant art scene by visiting the Magritte Museum, dedicated to the famous surrealist painter. Explore the city's numerous art galleries and catch a performance at the Royal Theatre for a taste of Belgian culture. Brussels truly has something for every art lover.
Food & nightlife
Indulge in delicious Belgian chocolates, waffles, and fries – a true foodie's paradise! As night falls, explore the lively pubs and bars around the city, or enjoy a fancy dinner in one of Brussels' many restaurants. Cheers to a memorable culinary adventure!
Shopping & fashion
From high-end boutiques to local markets, Brussels offers a diverse shopping experience. Explore the Galeries Royales Saint-Hubert for luxury brands or hunt for unique souvenirs in the Marolles district. Get ready to shop 'til you drop in style!
Nearby getaways
Venture beyond Brussels and discover charming nearby cities like Bruges and Ghent, known for their canals and medieval architecture. These easy day trips offer a delightful escape and a glimpse into Belgium's rich history. Perfect for a change of scenery!
Events in Brussels This Month
as brussels city b - rrc etterbeek b
Attend a thrilling football match in the 3rd Provincial B league, Walloon Brabant, Men's division, featuring AS Brussels City B versus RRC Etterbeek B. Witness local talent and enjoy an exciting game of football in Brussels.
Brussels Weather
Weather in Brussels
Wed, Dec 24
0%
2° -3°
0%
Thu, Dec 25
Frequently Asked Questions About Flights to Brussels
Pro Tips for Finding Cheap Flights to Brussels
Finally, to wrap up, here’s a cheat sheet of pro tips that experienced travelers use to save on Brussels flights:
Be Flexible with Your Dates: Flying on weekdays or during the off-season can unlock significantly cheaper fares. Who knew Tuesday could be the new Friday for travel deals?
Set Up Price Alerts: Use RatePunk to track flight prices and get notified when they drop! It's like having a personal flight deal hunter working for you 24/7.
