Cheap Flights from Santa Fe to Panama City
One-way
Departing from
Santa Fe
Going to
Panama City, United States
This is the lowest one-way flight price found by RatePunk users in the last 24 hours for a flight going to Panama City. Fares are subject to change and may not be available for all dates. (Data last updated 2/3/2026).
Popular airlines to Panama City
American Airlines
Air Canada
Aeroméxico
Avianca
Facts About Flights from Santa Fe to Panama City
To help you plan your journey, here are some quick Panama City flight facts and tips.
Panama City city airports
Panama City, Florida, is primarily served by the Northwest Florida Beaches International Airport (ECP). This modern airport offers a range of domestic flights, connecting travelers to major hubs and destinations across the United States. ECP provides a convenient gateway to the stunning beaches and attractions of Panama City Beach and the surrounding areas. With efficient services and a focus on passenger comfort, Northwest Florida Beaches International Airport ensures a smooth travel experience for visitors to this beautiful part of the Florida Panhandle.
Pro tip: search “Panama City (Any)” to see fares to all Panama City airports – sometimes one is cheaper than the others on your dates.
Insights for flights to Panama City
Cheapest airport
Panama City (PTY)
Tocumen International Airport (PTY) is the largest and busiest airport in Panama, located about 24 kilometers from Panama City. As a major hub for Copa Airlines, it offers flights to many destinations in Latin America, North America, Europe, and Asia, making it a crucial gateway to the Americas. Plus, who wouldn't want to start their Panama adventure with a splash of tropical vibes right from the get-go?
Nonstop vs. 1-stop
100+ cities
Panama City is a major hub in Central America, connecting over 100 cities across the Americas and beyond, with popular routes including Miami, Bogota, and Guayaquil.
Number of airlines
30+ airlines
Panama City is served by over 30 airlines, connecting you to destinations all over the world! Copa Airlines is the flag carrier, but you'll also find major players like United, Avianca, and Wingo offering competitive fares.
Typical price range (round-trip)
$200 - $600
Dreaming of Panama City? Flight prices typically range from $200 to $600, but watch out for peak seasons like holidays and summer, when prices tend to soar. Also, flights from major hubs can sometimes snag you a better deal, so keep an eye on those departure cities!
Flight frequency
500+ flights
There are usually over 500 flights to Panama City every week! Flights tend to be more frequent during peak seasons like the dry season (December to April) and around major holidays. You might also find more flights scheduled during the daytime hours to accommodate business travelers.
When Is the Best Time to Fly from Santa Fe to Panama City
Timing is everything when hunting for cheap flights. Here are data-backed insights on the best times to fly to Panama City:
Cheapest month
October
Cheapest month
October is typically the cheapest month to fly to Panama City! The weather is still warm and pleasant, making it perfect for exploring the city's attractions without the peak season crowds. Plus, you'll find great deals on flights and accommodations, leaving you with more cash to spend on delicious Panamanian cuisine!
Best day to book
Tuesday
Best day to book
Tuesday is often the best day to book a flight to Panama City! Airlines tend to release deals early in the week to fill up seats. Keep an eye on those mid-week prices for potential savings on your trip.
Cheapest days to fly
Wednesday
Cheapest days to fly
Wednesday is often the cheapest day to fly to Panama City! Flying mid-week can help you avoid the higher prices often associated with weekend travel. You will save some dollars to spend it on Panama City.
Advance booking sweet spot
2 Months
Advance booking sweet spot
The advance booking sweet spot for flights to Panama City tends to be around 2 months before your travel date! Booking around this time often gives you the best balance between price and availability. Waiting too long might mean higher fares, so plan ahead and snag those deals!
Panama City Airports & Ground Transportation
One big question for travelers is which Panama City airport to fly into. Here’s a quick guide to Panama City’s airports and how to get to the city from each:
Tocumen International Airport (PTY)
Tocumen International Airport is Panama City's primary international gateway, connecting you to a world of adventure! This bustling hub offers a variety of amenities, including duty-free shopping, restaurants, and comfortable lounges to relax in before your flight. Located about 24 kilometers from the city center, Tocumen is easily accessible by taxi, ride-sharing services, or the Metro Bus. The airport has undergone significant expansions in recent years, making it one of the most modern airports in Latin America. Be sure to check out the local Panamanian handicrafts available for sale.
Tip: Factor in extra time for immigration and security, especially during peak travel hours.
Panama Pacifico International Airport (BLB)
Panama Pacifico International Airport offers a convenient alternative for domestic and regional flights. Situated on the west side of the Panama Canal, this airport was formerly a US Air Force base. While smaller than Tocumen, it still provides essential services and a more relaxed atmosphere. Getting to and from the city center is easy with readily available taxis and ride-sharing options. It is a great starting point to explore the western side of Panama.
What to Do in Panama City
Panama City isn’t just about getting there – it’s about enjoying the country once you arrive! Here are some top things to do in Panama City, organized by interest:
Sightseeing & landmarks
Panama City is full of incredible sights! You can visit the Panama Canal, a true marvel of engineering, or explore the historic district of Casco Viejo with its beautiful colonial architecture. Don't forget to check out the Bridge of the Americas for a stunning view.
Arts & culture
Dive into Panama City's vibrant arts and culture scene by visiting the Biomuseo, designed by Frank Gehry, or catch a performance at the National Theatre. Wander through the city's museums and art galleries to discover the rich history and contemporary expressions of Panamanian culture.
Food & nightlife
Get ready to tantalize your taste buds with Panama City's diverse culinary scene! From traditional Panamanian dishes to international cuisine, there's something for everyone. As the sun sets, experience the lively nightlife with rooftop bars, dance clubs, and cozy pubs.
Shopping & fashion
Shopaholics, rejoice! Panama City offers a fantastic shopping experience, from modern malls like Multiplaza Pacific to local markets brimming with unique souvenirs. Explore the latest fashion trends and discover Panamanian crafts, ensuring you take home a piece of Panama's style.
Nearby getaways
Escape the city buzz with a short trip to nearby gems. Relax on the beautiful beaches of the Pearl Islands, hike through the lush rainforests of Soberania National Park, or explore the charming mountain town of El Valle de Anton. Adventure awaits just a stone's throw away!
Events in Panama City This Month
new years eve 2026 topgolf panama city beach
Celebrate the arrival of 2026 with an unforgettable New Year's Eve party at Topgolf in Panama City Beach! Enjoy a night filled with games, delicious food, great music, and plenty of cheers as you swing into the new year.
new year's eve at splash bar panama city beach
Join the New Year's Eve legendary party at Splash Bar on Panama City Beach! Get ready to ring in 2026 with the best bash around. It's a night that promises to be unlike any other, so bring in the New Year the right way!
todd allen herendeen
Attend a performance by Todd Allen Herendeen at Captain Anderson's Event Center in Panama City Beach on December 31, 2025, at 5:00 PM.
wednesday dec 31 vibez presents 5th annual nye party
Celebrate the New Year at the 5th Annual New Year's Eve Party hosted by Vibez, featuring cash prizes, giveaways, and festive party favors upon entry.
Frequently Asked Questions About Flights to Panama City
Pro Tips for Finding Cheap Flights to Panama City
Finally, to wrap up, here’s a cheat sheet of pro tips that experienced travelers use to save on Panama City flights:
Be Flexible with Travel Dates: Flying on weekdays or during the off-season can seriously slash those ticket prices to Panama City. Think of it as dodging the tourist rush and saving some serious dough!
Snag Early Bird Deals: Booking your flight well in advance – we're talking months – can help you grab those early bird specials. It’s like getting the worm, but instead of a worm, it's a sweet flight deal!
