$43 Cheap Flights from Knoxville

One-way

Departing from

Going to

Departing from

Knoxville

Going to

anywhere

Key West (EYW)

United States • January, 2026

97% AI deal score

$460 $43

Tokyo (HND)

Japan • January, 2026

96% AI deal score

$1,815 $520

Lisbon (LIS)

Portugal • May, 2026

95% AI deal score

$1,055 $412

Top Destinations Where Can You Fly from Knoxville

Cheap flights from Knoxville

Key West, United States

TOP

Jan • Direct

$460

$43

-$417

91%

Key West, United States

TOP

Feb • Direct

$460

$42

-$418

91%

Key West, United States

TOP

Jan • Direct

$460

$45

-$415

90%

Key West, United States

TOP

Jan • Direct

$460

$49

-$411

89%

Key West, United States

TOP

Jan • Direct

$460

$59

-$401

87%

Key West, United States

TOP

Jan • Direct

$460

$61

-$399

87%

Find flights from Knoxville to anywhere

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Looking for inspiration on destinations? Here are some popular flight deals from Knoxville one-way fares:

Sarasota, United States - from $36 (direct)

Washington, D.C., United States - from $36 (direct)

Jacksonville, United States - from $35 (direct)

Key West, United States - from $43 (direct)

Orlando, United States - from $45 (direct)

Fort Lauderdale, United States - from $49 (direct)

Punta Gorda, United States - from $52 (direct)

Philadelphia, United States - from $52 (direct)

Tampa, United States - from $53 (direct)

Boston, United States - from $54 (direct)

See more destinations you can fly to from Knoxville – anywhere in the world at the best prices.

See More Destinations

Last-Minute Flights from Knoxville

The best flight deals leaving from Knoxville soon

Mon, Jan 19

⌛ Last-Minute

Bangkok, Thailand

Knoxville (TYS) - Bangkok (DMK)

Allegiant Air airlines • 2 stops • New York (EWR), New Delhi (DEL)

$4,200

$650

-$3,550

85%

Mon, Jan 19

⌛ Last-Minute

Key West, United States

Knoxville (TYS) - Key West (EYW)

Allegiant Air airlines • Direct

$460

$45

-$415

90%

Mon, Jan 19

⌛ Last-Minute

Ottawa, Canada

Knoxville (TYS) - Ottawa (YOW)

United Airlines airlines • 1 stop • Washington, D.C. (IAD)

$360

$147

-$213

59%

Wed, Jan 21

⌛ Last-Minute

Tampa, United States

Knoxville (TYS) - Tampa (PIE)

Allegiant Air airlines • Direct

$173

$58

-$115

66%

Wed, Jan 21

⌛ Last-Minute

Bangkok, Thailand

Knoxville (TYS) - Bangkok (BKK)

United Airlines airlines • 3 stops • Houston (IAH), Los Angeles (LAX), Hong Kong (HKG)

$2,550

$443

-$2,107

83%

Thu, Jan 22

⌛ Last-Minute

Tampa, United States

Knoxville (TYS) - Tampa (PIE)

Allegiant Air airlines • Direct

$173

$58

-$115

66%

See More Details

Facts About Flights from Knoxville

Nearby airport(s)

McGhee Tyson (TYS)

Knoxville, United States

Insights for flights from Knoxville

Cheapest route found

$150

Recent fare for flights from Knoxville.

Cheapest month to fly

January

Average fares are lowest in this month.

Typical price range (round-trip)

150$ - 600$

For economy class tickets from Knoxville, found in the last week.

Most popular airlines from Knoxville

American Airlines

Alaska Airlines, Inc.

JetBlue Airways

Delta Air Lines

Frontier Airlines

Allegiant Air

Spirit Airlines

TYS Airport Deal Stats

Current most discounted routes

TYS - Bangkok

87% OFF

TYS - Bangkok

83% OFF

TYS - Edinburgh

82% OFF

Avg. most discounted routes (last 3 months)

TYS - Amsterdam

81% OFF

TYS - Barcelona

81% OFF

TYS - Paris

80% OFF

TYS airport insights

Best days to catch a deal

Thursday, Saturday

To snag the best flight deals from McGhee Tyson Airport, focus on booking flights that depart on Mondays, as they have the highest probability of deals. Sundays also have some deals available from McGhee Tyson Airport, but Monday has better options.

Avg. deal survival time

15.3 hours

Deals from McGhee Tyson airport last an average of 15.3 hours. Make sure to book quickly, as deals typically don't last longer than that!

Rare deal frequency

11 deals

We have identified 11 rare flight deals from {{ McGhee Tyson }} airport in the last month. These rare deals, typically mistake fares, special promotions, or ultra-discounts, achieved an AI Deal Score of 90 or higher.

Average price drop

-70%

Deals that originate from McGhee Tyson airport see an average price drop of 69.7%. This is a great incentive to book flights from McGhee Tyson.

Next 4 weeks: deal forecast

McGhee Tyson Flight Forecast

Based on our current forecast, flights from McGhee Tyson Airport are expected to remain stable next month. We do not anticipate any significant price drops or increases at this time.

Top 5 biggest price drops (last 3 months)

Found on January 3

TYS - Bangkok

$4,200 → $555

87%

Found on January 8

TYS - Bangkok

$2,550 → $443

83%

Found on January 6

TYS - Edinburgh

$1,325 → $238

82%

Found on January 6

TYS - Amsterdam

$1,205 → $230

81%

Found on January 6

TYS - Barcelona

$1,340 → $250

81%

Check these nearby airports too

Looking for more options? These airports near TYS sometimes drop rare deals too:

Asheville Regional (AVL)

~9 rare deals/month

Nashville International (BNA)

~9 rare deals/month

Tri-Cities Regional (TRI)

~6 rare deals/month

If you’re flexible with departure cities, it’s worth keeping an eye on nearby airports — especially AVL and BNA for long-haul deal surprises.

Travel Trends: Popular Destinations from Knoxville

Every month, we analyze search and booking data to see where travelers from Knoxville are heading. Here are the current hot destinations from Knoxville:

Top domestic destinations

Atlanta

TOP

Knoxville

Chicago

TOP

Knoxville

Orlando

TOP

Knoxville

These cities are seeing the most searches and bookings from Knoxville this month.

Top international destinations

London

TOP

United Kingdom

Paris

TOP

France

Travelers from Knoxville are flocking here, possibly due to seasonal events or great deals.

Travel trend insight

Knoxville travelers are increasingly drawn to destinations with rich history and culture. London and Paris are trending due to their iconic landmarks, world-class museums, and immersive cultural experiences that offer unique and memorable travel opportunities.

Booking Flights from Knoxville: Frequently Asked Questions

Flight costs from Knoxville vary wildly depending on the destination, time of year, and how far in advance you book. For domestic flights, expect to pay anywhere from $100 to $500, while international flights can range from $500 to several thousand dollars. To snag the best deals, be flexible with your travel dates, consider flying during the off-season, and set up fare alerts on websites like RatePunk Flights Search to be notified when prices drop. Also, keep an eye out for last-minute deals and consider flying on Tuesdays or Wednesdays, which are often cheaper.

Generally, the sweet spot for booking flights is about 2-3 months in advance for domestic travel and 3-6 months for international flights. However, this isn't a hard-and-fast rule, and prices can fluctuate. Avoid booking during peak travel times like holidays and summer vacations, as prices tend to skyrocket. Consider using fare prediction tools to monitor price trends and book when you see a dip. Remember, flexibility is your friend—being open to different travel dates can save you a bundle.

From Knoxville, popular destinations include major hubs like Atlanta, Charlotte, and Dallas, which offer convenient connections to countless other cities. Cities like Orlando and Tampa in Florida are also popular, especially for vacationers seeking sun and fun. The appeal of these destinations lies in their accessibility and the variety of attractions they offer, whether it's business opportunities, family-friendly entertainment, or simply a change of scenery. Plus, these routes often have more frequent flights, increasing your chances of finding a good deal.

Pro Tips for Finding Cheap Flights from Knoxville

Finding the cheapest airfare from Knoxville is easier if you use a few smart strategies. Here are our top tips to help you score a great deal:

Be Flexible with Dates: Flying on Tuesdays, Wednesdays, or Saturdays is often cheaper than flying on weekends. Play around with your dates to see if you can snag a better deal. Even shifting your travel by a day or two can lead to significant savings!

Knoxville is great, but checking alternative airports like Nashville or Asheville could unlock cheaper flights. A little extra drive time might save you a bundle on airfare! Just be sure to factor in the cost of getting to and from the alternative airport.

Explore More Destinations from Knoxville

Looking for more options? Here are some popular routes and related travel deals:

Flights from Knoxville to Amsterdam - Find cheap flights from Knoxville to AMS

Flights from Knoxville to Madrid - Find cheap flights from Knoxville to MAD

Cheap flights to Knoxville - Searching for cheap flights to Knoxville? (Great for fiends/family visiting you, or return trips.)

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$43 Cheap Flights from Knoxville

Top Destinations Where Can You Fly from Knoxville

Cheap flights from Knoxville

Key West, United States

$43

Key West, United States

$42

Key West, United States

$45

Key West, United States

$49

Key West, United States

$59

Key West, United States

$61

Find flights from Knoxville to anywhere

Last-Minute Flights from Knoxville

The best flight deals leaving from Knoxville soon

Mon, Jan 19

Knoxville (TYS) - Bangkok (DMK)

$650

Mon, Jan 19

Knoxville (TYS) - Key West (EYW)

$45

Mon, Jan 19

Knoxville (TYS) - Ottawa (YOW)

$147

Wed, Jan 21

Knoxville (TYS) - Tampa (PIE)

$58

Wed, Jan 21

Knoxville (TYS) - Bangkok (BKK)

$443

Thu, Jan 22

Knoxville (TYS) - Tampa (PIE)

$58

Facts About Flights from Knoxville

Nearby airport(s)

McGhee Tyson (TYS)

Insights for flights from Knoxville

$150

January

150$ - 600$

Most popular airlines from Knoxville

TYS Airport Deal Stats

Current most discounted routes

Avg. most discounted routes (last 3 months)

TYS airport insights

Thursday, Saturday

15.3 hours

11 deals

-70%

McGhee Tyson Flight Forecast

Top 5 biggest price drops (last 3 months)

TYS - Bangkok

TYS - Bangkok

TYS - Edinburgh

TYS - Amsterdam

TYS - Barcelona

Check these nearby airports too

Asheville Regional (AVL)

Nashville International (BNA)

Tri-Cities Regional (TRI)

Travel Trends: Popular Destinations from Knoxville

Top domestic destinations

Atlanta

Chicago

Orlando

Top international destinations

London

Paris

Travel trend insight

Booking Flights from Knoxville: Frequently Asked Questions

What is the average cost of a flight from Knoxville, and how can I find the best deals?

What is the average cost of a flight from Knoxville, and how can I find the best deals?

When is the best time to book flights from Knoxville to get the lowest prices?

When is the best time to book flights from Knoxville to get the lowest prices?