To Santiago de Chile

Cheap Flights from Cancún to Santiago de Chile

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Cancún

RatePunk searches hundreds of travel sites at once for deals on flights to Santiago de Chile

Prices updated 24 days ago

486,190 searches this week

171 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)

Today’s best flight deals from Cancún to Santiago de Chile

Explore current cheapest deals departing from Cancún to Santiago de Chile

Round trip

Sort by: Cheapest

September 15 - September 28

Cheapest

CUN - Santiago de Chile

$510

$490

Round trip

September 13 - September 19

Earliest

CUN - Santiago de Chile

$525

$519

Round trip

September 24 - September 30

CUN - Santiago de Chile

$532

$530

Round trip

September 13 - September 23

Earliest

CUN - Santiago de Chile

$510

$543

Round trip

September 13 - September 28

Earliest

CUN - Santiago de Chile

$504

$553

Round trip

September 24 - September 28

CUN - Santiago de Chile

$550

$553

Round trip

September 15 - September 30

CUN - Santiago de Chile

$506

$555

Round trip

September 15 - October 14

CUN - Santiago de Chile

$502

$555

Round trip

September 15 - October 5

CUN - Santiago de Chile

$503

$555

Round trip

November 1 - November 2

Best

CUN - Santiago de Chile

$616

$565

Round trip

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Route Intelligence — 486,190 Searches this Week

Insights for flights from Cancún to Santiago de Chile

Most itineraries for flights from Cancún to Santiago de Chile connect at least once, with only 2.5% of recent fares being non-stop. For the vast majority of journeys that include connections, travelers typically encounter 1 stopover. This means that while direct flights from Cancún to Santiago de Chile are rare, connecting options are readily available.

When considering cheap flights from Cancún to Santiago de Chile, fares typically range from $364 –$552, with a median of $376. Right now, current fares are near the typical level. A significant share of recent fares, specifically 56%, were classified as a good price, indicating that favorable deals are often available for this route. New deals for this route appear almost daily, making it beneficial to monitor prices regularly.

A typical journey from Cancún to Santiago de Chile, including connections, takes approximately 11h 58m. This duration reflects the long-haul nature of the route, which covers a substantial distance.

The route from Cancún to Santiago de Chile is classified as a long-haul journey, spanning a distance of 6288 kilometers. This considerable distance contributes to the typical flight duration and the prevalence of connecting itineraries.

If you are looking for the cheapest time to fly from Cancún to Santiago de Chile, December stands out with a median fare of just $255. Other cost-effective months include March, with a median fare of $369, and April, where the median fare is $370. These months offer more budget-friendly options compared to the overall median fare for the route.

How much is a round trip from Cancún to Santiago de Chile

Regular price: $462 - $1,048

Prices for flights from Cancún to Santiago de Chile are currently within the regular range.

The regular price range for flights from Cancún to Santiago de Chile is between $462 and $1048. The current lowest deal is $490 with Maersk Air. This deal is for travel from September 15 to September 28.

now $490

Low $462

High $1,048

The cheapest time to fly from Cancún to Santiago de Chile

The cheapest month to fly from Cancun to Santiago is December, with a median price of $255. The most expensive month is October, with a median price of $641. Prices are generally lower from January to December.

December

Cheapest

Flights from $255

October

Most Expensive

Flights from $641

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Cancún to Santiago de Chile

LATAM Chile

Last-minute flights going from Cancún to Santiago de Chile

Thu, Jun 18

⌛ Last-Minute

CUN - Santiago de Chile

Cancún (CUN) - Santiago de Chile (SCL)

Maersk Air

$761

$654

One-way

Fri, Jun 19

⌛ Last-Minute

CUN - Santiago de Chile

Cancún (CUN) - Santiago de Chile (SCL)

Avianca

$679

$698

One-way

Fri, Jun 19

⌛ Last-Minute

CUN - Santiago de Chile

Cancún (CUN) - Santiago de Chile (SCL)

LATAM Chile

$761

$716

One-way

Fri, Jun 19

⌛ Last-Minute

CUN - Santiago de Chile

Cancún (CUN) - Santiago de Chile (SCL)

Avianca

$712

$753

One-way

Fri, Jun 19

⌛ Last-Minute

CUN - Santiago de Chile

Cancún (CUN) - Santiago de Chile (SCL)

LATAM Chile

$766

One-way

Sat, Jun 20

⌛ Last-Minute

CUN - Santiago de Chile

Cancún (CUN) - Santiago de Chile (SCL)

Avianca

$759

$756

One-way

Biggest price drops on these dates for flights from Cancún to Santiago de Chile

3 nights

Jun 18 - Jun 21

$761 → $654

14%

1 night

Nov 1 - Nov 2

$616 → $565

3 nights

Jun 19 - Jun 22

$761 → $716

4 nights

Aug 13 - Aug 17

$688 → $647

Popular Airports to fly from Cancún to Santiago de Chile

Cancún - Santiago de Chile route insights

💸 Price insights

Recent fares are near the typical level

Recent fares for Cancún to Santiago de Chile are near the typical level, with a median of $376.

📅 Best time to fly

December is historically the cheapest month

Historically, December is the cheapest month to fly from Cancún to Santiago de Chile, with a median price of $255.

⏱️ Flight duration

Connecting flights typically take 11h 58m

The typical flight duration from Cancún to Santiago de Chile is 11h 58m, with 1 stopover.

✈️ Airlines & availability

Connecting flights are dominant on this route

Connecting flights are dominant on this route, making up 97.5% of recent deals.

🏆 Airline highlight

LATAM Chile offers direct flights

LATAM Chile is an airline offering direct flights from Cancún to Santiago de Chile.

🎯 Booking tip

Deals appear frequently (1+ per day)

Deals for flights from Cancún to Santiago de Chile appear frequently, averaging 1.03 per day.

Cancún main airports to depart from

Cancún International (CUN)

Cheapest

Cancún International Airport is a convenient departure point for flights to Santiago de Chile.

📍 ~20 km from Cancún (reachable by car)

💸 Flights from ~$490

Santiago de Chile main airports to arrive at

Comodoro Arturo Merino Benítez International (SCL)

Cheapest

Comodoro Arturo Merino Benítez International Airport is the primary gateway for flights arriving in Santiago de Chile.

📍 ~15 km from city center (reachable by car)

💸 Flights from ~$490

Airports nearby Santiago de Chile used as alternative

Governor Francisco Gabrielli International (MDZ)

Consider Mendoza as an international alternative, but note the required border crossing and potential winter pass closures.

📍 ~135 km from Santiago de Chile (reachable by car)

💸 Flights from ~$608

Carriel Sur International (CCP)

Concepción is a major domestic alternative within Chile, avoiding international border formalities.

📍 ~420 km from Santiago de Chile (reachable by car)

💸 Flights from ~$696

La Florida (LSC)

La Serena is a reliable domestic alternative to the north, with no border crossing required.

📍 ~470 km from Santiago de Chile (reachable by car)

💸 Flights from ~$681

Ingeniero Aeronáutico Ambrosio L.V. Taravella International (COR)

Cheapest

Cordoba is a major international hub, but it is a very long distance from Santiago and requires a border crossing.

📍 ~400 km from Santiago de Chile (reachable by flight or lengthy drive)

💸 Flights from ~$498

La Araucanía International (ZCO)

La Araucanía is a modern domestic alternative in southern Chile, primarily serving as a regional hub.

📍 ~620 km from Santiago de Chile (reachable by car)

💸 Flights from ~$704

Business & First Class Flight Deals to Santiago de Chile

89% AI deal score

$2,416

$1,914

Save $502

Frequently Asked Questions About Flights to Santiago de Chile

Historically, the optimal time to book flights from Cancún to Santiago de Chile is within 0-6 days of departure. During this period, the average price for flights was approximately $379. Booking 7-13 days out typically saw prices around $510, while booking 14-27 days in advance had an average price of $391. For those planning further ahead, flights booked 60+ days out averaged around $519.

Across the trailing quarter, a good price for a flight from Cancún to Santiago de Chile was considered to be $364 or less. The median price for this route was $376. Approximately 25% of all observed prices were at or below $364, while 75% of prices were at or below $552.

Historically, December has been the most affordable month to fly from Cancún to Santiago de Chile, with a median price of $255. March and April also offered competitive prices, with median fares of $369 and $370 respectively. The annual median price for this route was $376, indicating that December provided a significant saving compared to the yearly average.

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