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Cheap Flights from Greenville to San Francisco

Browse current best options from Greenville. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Greenville

RatePunk searches hundreds of travel sites at once for deals on flights to San Francisco

Prices updated 24 days ago

486,190 searches this week

171 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)

Today’s best flight deals from Greenville to San Francisco

Explore current cheapest deals departing from Greenville to San Francisco

Round trip

Sort by: Cheapest

September 23 - September 29

Cheapest

Best

GSP - San Francisco

$393

$300

Round trip

July 14 - July 21

GSP - San Francisco

$402

$362

Round trip

August 11 - August 18

GSP - San Francisco

$343

$362

Round trip

August 18 - August 25

GSP - San Francisco

$345

$362

Round trip

September 8 - September 15

GSP - San Francisco

$381

$362

Round trip

September 24 - September 30

GSP - San Francisco

$396

$371

Round trip

October 1 - October 6

GSP - San Francisco

$445

$371

Round trip

July 9 - July 12

Earliest

GSP - San Francisco

$427

$378

Round trip

October 1 - October 5

GSP - San Francisco

$446

$380

Round trip

August 16 - August 18

GSP - San Francisco

$363

$384

Round trip

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Route Intelligence — 486,190 Searches this Week

Insights for flights from Greenville to San Francisco

Most itineraries from Greenville to San Francisco connect at least once, with 0% of recent fares being non-stop. For the remaining itineraries, the typical number of connections is 2. This means you should expect to include layovers in your travel plans when flying this route.

When looking for cheap flights from Greenville to San Francisco, fares typically range from $477–$723, with a median of $505. Right now, fares are below the typical level, and only 3% of recent fares were classified as a good price. New deals appear almost daily, suggesting frequent opportunities to find better prices.

The cheapest time to fly from Greenville to San Francisco is typically in February, with a median fare of $234. Other affordable months include December, where the median fare is $310, and January, with a median fare of $343. Planning your trip during these months can lead to significant savings.

A typical journey from Greenville to San Francisco takes about 17h 4m, including connections. This duration accounts for the fact that most flights on this route involve at least one stopover, often two, extending the total travel time considerably.

The distance between Greenville and San Francisco is 3587 km, classifying this as a medium-haul route. This distance typically involves a longer flight duration and often requires connecting flights to reach your destination.

How much is a round trip from Greenville to San Francisco

Regular price: $329 - $590

Prices for flights from Greenville to San Francisco are currently below the regular range.

The regular price range for flights from Greenville to San Francisco is typically between $329 and $590. The current lowest deal is $300 with Deutsche Luft Hansa, for travel from Sep 23 to Sep 29.

now $300

Low $329

High $590

The cheapest time to fly from Greenville to San Francisco

The cheapest month to fly from GSP to SFO is February, with a median price of $234. The most expensive month is July, with a median price of $873. Prices are generally lower from January to December.

February

Cheapest

Flights from $234

July

Most Expensive

Flights from $873

Jan

Feb

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Greenville to San Francisco

Allegiant Air

JetBlue Airways

Breeze Airways

United Airlines

Last-minute flights going from Greenville to San Francisco

Sat, Jun 20

⌛ Last-Minute

GSP - San Francisco

Greenville (GSP) - San Francisco (SFO)

American Airlines

$496

$956

One-way

Thu, Jun 25

⌛ Last-Minute

GSP - San Francisco

Greenville (GSP) - San Francisco (SFO)

Allegiant Air

$475

$569

One-way

Wed, Jul 1

⌛ Last-Minute

GSP - San Francisco

Greenville (GSP) - San Francisco (SFO)

Allegiant Air

$413

$433

One-way

Thu, Jul 2

⌛ Last-Minute

GSP - San Francisco

Greenville (GSP) - San Francisco (SFO)

Allegiant Air

$401

$416

One-way

Thu, Jul 2

⌛ Last-Minute

GSP - San Francisco

Greenville (GSP) - San Francisco (SFO)

Allegiant Air

$411

$454

One-way

Thu, Jul 2

⌛ Last-Minute

GSP - San Francisco

Greenville (GSP) - San Francisco (SFO)

American Airlines

$452

$490

One-way

Biggest price drops on these dates for flights from Greenville to San Francisco

6 nights

Sep 23 - Sep 29

$393 → $300

24%

5 nights

Oct 1 - Oct 6

$445 → $371

17%

4 nights

Oct 1 - Oct 5

$446 → $380

15%

3 nights

Jul 9 - Jul 12

$427 → $378

12%

Popular Airports to fly from Greenville to San Francisco

Greenville - San Francisco route insights

💸 Price insights

Recent fares are below the typical level.

Recent fares are below the typical level for the GSP to SFO route.

📅 Best time to fly

Fly in February for the best prices.

Historically, February offers the lowest median price at $234, significantly cheaper than other months.

⏱️ Flight duration

Connecting flights average 17h 4m.

Flights from Greenville to San Francisco typically involve connecting, with a median duration of 17h 4m.

✈️ Airlines & availability

Frequent deals are available.

This route frequently has deals, with over one deal available per day historically.

🏆 Airline highlight

Deutsche Luft Hansa offers a recent deal for $300.

A recent deal from Deutsche Luft Hansa was found for $300, departing September 23.

🎯 Booking tip

Consider booking during cheaper months.

For better prices, consider flying in February, December, or January, which are historically cheaper.

Greenville main airports to depart from

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International is a good choice for flights from Greenville to San Francisco.

📍 ~18 km from Greenville (reachable by car)

💸 Flights from ~$300

San Francisco main airports to arrive at

San Francisco International (SFO)

Cheapest

San Francisco International Airport is a good choice for reaching San Francisco and the Bay Area.

📍 ~20 km from San Francisco (reachable by car, public transport)

💸 Flights from ~$300

Airports nearby San Francisco used as alternative

Oakland International (OAK)

Oakland International is a useful alternative arrival airport with direct BART public transit access to San Francisco.

📍 ~18 km from San Francisco (reachable by public transit)

💸 Flights from ~$443

San Jose International (SJC)

Cheapest

San Jose International is a major international airport serving the South Bay tech corridor with fewer weather delays.

📍 ~70 km from San Francisco (reachable by car)

💸 Flights from ~$356

Sacramento International (SMF)

Sacramento International offers a robust domestic route network for travelers in the northern and eastern metro areas.

📍 ~120 km from San Francisco (reachable by car)

💸 Flights from ~$363

Charles M. Schulz–Sonoma County (STS)

Charles M. Schulz–Sonoma County is convenient for travelers in the North Bay and Wine Country.

📍 ~90 km from San Francisco (reachable by car)

💸 Flights from ~$531

Monterey Regional (MRY)

Monterey Regional is an alternative for travelers in the southern coastal region with a less crowded terminal.

📍 ~140 km from San Francisco (reachable by car)

💸 Flights from ~$395

Business & First Class Flight Deals to San Francisco

San Francisco, United States

49% AI deal score

$3,765

From GSP

Elite

Nov 20

San Francisco, United States

49% AI deal score

$3,974

Frequently Asked Questions About Flights to San Francisco

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also reveal better deals. Setting up price alerts may help you track fare changes.

Booking flights in advance often provides more options and potentially lower prices. However, last-minute deals can sometimes appear, though they are less common. It's usually beneficial to monitor prices over time.

Comparing nearby airports at both your origin and destination can sometimes uncover more economical flight options. While it may add to travel time, the potential savings can be significant. Always check ground transportation costs and convenience.

Related routes

Consider alternative routes from Greenville

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