Cheap Flights from Guayaquil to Santo Domingo
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Prices updated 24 days ago
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171 airlines compared
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Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)
Today’s best flight deals from Guayaquil to Santo Domingo
Explore current cheapest deals departing from Guayaquil to Santo Domingo
Round trip
Sort by: Cheapest
August 13 - August 17
GYE - Santo Domingo
$465
$431
Round trip
June 19 - June 25
GYE - Santo Domingo
$586
$434
Round trip
June 22 - June 29
GYE - Santo Domingo
$583
$434
Round trip
August 14 - August 16
GYE - Santo Domingo
$466
$434
Round trip
August 7 - August 10
GYE - Santo Domingo
$469
$434
Round trip
August 7 - August 13
GYE - Santo Domingo
$449
$434
Round trip
August 11 - August 17
GYE - Santo Domingo
$448
$434
Round trip
June 18 - June 24
GYE - Santo Domingo
$586
$435
Round trip
July 24 - July 28
GYE - Santo Domingo
$453
$435
Round trip
July 9 - July 13
GYE - Santo Domingo
$471
$435
Round trip
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Route Intelligence — 486,190 Searches this Week
Insights for flights from Guayaquil to Santo Domingo
How much is a round trip from Guayaquil to Santo Domingo
Regular price: $378 - $694
Prices for flights from Guayaquil to Santo Domingo are currently within the regular range.
The regular price range for this route is between $378 and $694. The current lowest deal is $431 with Copa Airlines, for travel from August 13 to August 17, 2026.
now $431
Low $378
High $694
The cheapest time to fly from Guayaquil to Santo Domingo
The cheapest month to fly from GYE to SDQ is June, with a median price of $283. The most expensive month is September, with a median price of $416. Prices are generally lower from March to November.
June
Flights from $283
September
Flights from $416
Direct flights from Guayaquil to Santo Domingo
Copa Airlines
Avianca
Last-minute flights going from Guayaquil to Santo Domingo
Thu, Jun 18
GYE - Santo Domingo
Guayaquil (GYE) - Santo Domingo (SDQ)
Copa Airlines
$586
$435
One-way
Fri, Jun 19
GYE - Santo Domingo
Guayaquil (GYE) - Santo Domingo (SDQ)
Copa Airlines
$586
$434
One-way
Fri, Jun 19
GYE - Santo Domingo
Guayaquil (GYE) - Santo Domingo (SDQ)
Copa Airlines
$538
$457
One-way
Fri, Jun 19
GYE - Santo Domingo
Guayaquil (GYE) - Santo Domingo (SDQ)
Copa Airlines
$586
$558
One-way
Mon, Jun 22
GYE - Santo Domingo
Guayaquil (GYE) - Santo Domingo (SDQ)
Copa Airlines
$583
$434
One-way
Thu, Jun 25
GYE - Santo Domingo
Guayaquil (GYE) - Santo Domingo (SDQ)
Copa Airlines
$564
$436
One-way
Biggest price drops on these dates for flights from Guayaquil to Santo Domingo
Jun 27 - Jun 30
$603 → $436
28%
Jun 27 - Jun 29
$599 → $437
27%
Jun 28 - Jun 30
$595 → $437
27%
Jun 19 - Jun 25
$586 → $434
26%
Popular Airports to fly from Guayaquil to Santo Domingo
Guayaquil - Santo Domingo route insights
💸 Price insights
Recent fares are near the typical level.
Recent fares for Guayaquil to Santo Domingo are near the typical level of $323.
📅 Best time to fly
June is historically the cheapest month to fly.
Historically, the cheapest month to fly from Guayaquil to Santo Domingo is June, with a median price of $283.
⏱️ Flight duration
Connecting flights take 7h 44m on average.
Flights from Guayaquil to Santo Domingo typically take 7h 44m, with 1 stopover on average.
✈️ Airlines & availability
Frequent deals are available on this route.
This route sees frequent deals, with over 1 deal per day historically available.
🏆 Airline highlight
Copa Airlines offers the most deals.
Copa Airlines historically offers the most deals for flights from Guayaquil to Santo Domingo.
🎯 Booking tip
Consider flying in June for better prices.
Historically, June offers the lowest median prices for flights from Guayaquil to Santo Domingo.
Guayaquil main airports to depart from
José Joaquín de Olmedo International (GYE)
José Joaquín de Olmedo International (GYE) is the cheapest option for flights from Guayaquil to Santo Domingo.
📍 ~5 km from Guayaquil city center (reachable by car)
💸 Flights from ~$431
Santo Domingo main airports to arrive at
Las Américas International (SDQ)
Las Américas International Airport is a convenient arrival option for flights to Santo Domingo from Guayaquil.
📍 ~28 km from Santo Domingo (reachable by car)
💸 Flights from ~$431
La Isabela International (JBQ)
La Isabela International Airport offers another arrival choice for those flying to Santo Domingo from Guayaquil.
📍 ~11 km from Santo Domingo (reachable by car)
💸 Flights from ~$926
Airports nearby Santo Domingo used as alternative
Punta Cana International (PUJ)
Consider Punta Cana International for its extensive global flight network and often competitive pricing.
📍 ~175 km from Santo Domingo (reachable by car)
💸 Flights from ~$314
Cibao International (STI)
Cibao International is a reliable alternative for regional and North American travel with good highway access.
📍 ~150 km from Santo Domingo (reachable by car)
💸 Flights from ~$480
Gregorio Luperón International (POP)
Gregorio Luperón International is a major airport on the north coast, useful if other flights are unavailable.
📍 ~190 km from Santo Domingo (reachable by car)
💸 Flights from ~$525
Samaná El Catey International (AZS)
Samaná El Catey International is geographically close and modern, but has a very limited flight schedule.
📍 ~100 km from Santo Domingo (reachable by car)
💸 Flights from ~$1889
Business & First Class Flight Deals to Santo Domingo
Discover luxury on the budget with premium cabin class on flights from Guayaquil to Santo Domingo.
Elite
Best Elite deals to Santo Domingo
Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.
From GYE
Elite
Aug 24
Santo Domingo, Dominican Republic
87% AI deal score
$1,443
$810
Save $633
From GYE
Elite
Oct 24
Santo Domingo, Dominican Republic
87% AI deal score
$1,533
$810
Save $723
From GYE
Elite
Oct 24
Santo Domingo, Dominican Republic
87% AI deal score
$1,509
$810
Save $699
From GYE
Elite
Sep 26
Santo Domingo, Dominican Republic
87% AI deal score
$1,487
$810
Save $677
From GYE
Elite
Aug 13
Santo Domingo, Dominican Republic
86% AI deal score
$1,356
$810
Save $546
From GYE
Elite
Aug 12
Santo Domingo, Dominican Republic
86% AI deal score
$1,339
$810
Save $529
From GYE
Elite
Aug 21
Santo Domingo, Dominican Republic
86% AI deal score
$1,364
$810
Save $554
From GYE
Elite
Aug 13
Santo Domingo, Dominican Republic
86% AI deal score
$1,341
$810
Save $531
From GYE
Elite
Aug 07
Santo Domingo, Dominican Republic
86% AI deal score
$1,340
$810
Save $530
From GYE
Elite
Aug 12
Santo Domingo, Dominican Republic
86% AI deal score
$1,353
$810
Save $543
From GYE
Elite
Oct 10
Santo Domingo, Dominican Republic
86% AI deal score
$1,450
$810
Save $640
From GYE
Elite
Oct 10
Santo Domingo, Dominican Republic
86% AI deal score
$1,450
$810
Save $640
From GYE
Elite
Oct 13
Santo Domingo, Dominican Republic
86% AI deal score
$1,451
$810
Save $641
From GYE
Elite
Oct 10
Santo Domingo, Dominican Republic
86% AI deal score
$1,446
$810
Save $636
From GYE
Elite
Oct 06
Santo Domingo, Dominican Republic
86% AI deal score
$1,425
$810
Save $615
From GYE
Elite
Oct 15
Santo Domingo, Dominican Republic
86% AI deal score
$1,452
$810
Save $642
From GYE
Elite
Oct 15
Santo Domingo, Dominican Republic
86% AI deal score
$1,451
$810
Save $641
From GYE
Elite
Oct 15
Santo Domingo, Dominican Republic
86% AI deal score
$1,462
$810
Save $652
From GYE
Elite
Oct 24
Santo Domingo, Dominican Republic
86% AI deal score
$1,479
$810
Save $669
From GYE
Elite
Oct 14
Santo Domingo, Dominican Republic
86% AI deal score
$1,451
$810
Save $641
From GYE
Elite
Oct 06
Santo Domingo, Dominican Republic
86% AI deal score
$1,425
$810
Save $615
From GYE
Elite
Oct 13
Santo Domingo, Dominican Republic
86% AI deal score
$1,459
$810
Save $649
From GYE
Elite
Oct 14
Santo Domingo, Dominican Republic
86% AI deal score
$1,452
$810
Save $642
From GYE
Elite
Oct 21
Santo Domingo, Dominican Republic
86% AI deal score
$1,441
$810
Save $631
From GYE
Elite
Oct 14
Santo Domingo, Dominican Republic
86% AI deal score
$1,459
$810
Save $649
From GYE
Elite
Oct 21
Santo Domingo, Dominican Republic
86% AI deal score
$1,446
$810
Save $636
From GYE
Elite
Oct 13
Santo Domingo, Dominican Republic
86% AI deal score
$1,457
$810
Save $647
From GYE
Elite
Oct 21
Santo Domingo, Dominican Republic
86% AI deal score
$1,444
$810
Save $634
From GYE
Elite
Oct 06
Santo Domingo, Dominican Republic
86% AI deal score
$1,425
$810
Save $615
From GYE
Elite
Jun 20
Santo Domingo, Dominican Republic
86% AI deal score
$1,549
$867
Save $682
From GYE
Elite
Jun 22
Santo Domingo, Dominican Republic
86% AI deal score
$1,592
$867
Save $725
From GYE
Elite
Aug 07
Santo Domingo, Dominican Republic
85% AI deal score
$1,321
$810
Save $511
From GYE
Elite
Jul 29
Santo Domingo, Dominican Republic
85% AI deal score
$1,405
$810
Save $595
From GYE
Elite
Jul 29
Santo Domingo, Dominican Republic
85% AI deal score
$1,420
$810
Save $610
From GYE
Elite
Jul 27
Santo Domingo, Dominican Republic
85% AI deal score
$1,407
$810
Save $597
From GYE
Elite
Jul 13
Santo Domingo, Dominican Republic
68% AI deal score
$1,921
From GYE
Elite
Jul 13
Santo Domingo, Dominican Republic
68% AI deal score
$1,987
From GYE
Elite
Aug 04
Santo Domingo, Dominican Republic
68% AI deal score
$2,016
From GYE
Elite
Jul 13
Santo Domingo, Dominican Republic
68% AI deal score
$2,059
From GYE
Elite
Dec 08
Santo Domingo, Dominican Republic
68% AI deal score
$2,064
From GYE
Elite
Dec 08
Santo Domingo, Dominican Republic
68% AI deal score
$2,064
From GYE
Elite
Jul 06
Santo Domingo, Dominican Republic
68% AI deal score
$2,084
From GYE
Elite
Jul 03
Santo Domingo, Dominican Republic
68% AI deal score
$2,095
From GYE
Elite
Aug 03
Santo Domingo, Dominican Republic
68% AI deal score
$2,168
From GYE
Elite
Dec 08
Santo Domingo, Dominican Republic
68% AI deal score
$2,184
From GYE
Elite
Jul 26
Santo Domingo, Dominican Republic
68% AI deal score
$2,207
From GYE
Elite
Dec 08
Santo Domingo, Dominican Republic
68% AI deal score
$2,209
From GYE
Elite
Aug 04
Santo Domingo, Dominican Republic
68% AI deal score
$2,210
From GYE
Elite
Jul 06
Santo Domingo, Dominican Republic
68% AI deal score
$2,222
From GYE
Elite
Aug 04
Santo Domingo, Dominican Republic
68% AI deal score
$2,246
From GYE
Elite
Dec 08
Santo Domingo, Dominican Republic
68% AI deal score
$2,252
From GYE
Elite
Jul 09
Santo Domingo, Dominican Republic
68% AI deal score
$2,271
From GYE
Elite
Jul 06
Santo Domingo, Dominican Republic
68% AI deal score
$2,306
From GYE
Elite
Jul 03
Santo Domingo, Dominican Republic
68% AI deal score
$2,317
From GYE
Elite
Dec 08
Santo Domingo, Dominican Republic
68% AI deal score
$2,351
From GYE
Elite
Aug 03
Santo Domingo, Dominican Republic
68% AI deal score
$2,362
From GYE
Elite
Aug 11
Santo Domingo, Dominican Republic
68% AI deal score
$2,362
From GYE
Elite
Jul 06
Santo Domingo, Dominican Republic
67% AI deal score
$2,419
From GYE
Elite
Jul 06
Santo Domingo, Dominican Republic
67% AI deal score
$2,481
From GYE
Elite
Jul 06
Santo Domingo, Dominican Republic
67% AI deal score
$2,685
From GYE
Elite
Jul 03
Santo Domingo, Dominican Republic
67% AI deal score
$2,794
From GYE
Elite
Jul 10
Santo Domingo, Dominican Republic
67% AI deal score
$2,843
From GYE
Elite
Jun 25
Santo Domingo, Dominican Republic
46% AI deal score
$2,108