To Guayaquil

Cheap Flights from Medellín to Guayaquil

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Deals from

Medellín

RatePunk searches hundreds of travel sites at once for deals on flights to Guayaquil

Prices updated 24 days ago

486,190 searches this week

171 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)

Today’s best flight deals from Medellín to Guayaquil

Explore current cheapest deals departing from Medellín to Guayaquil

Round trip

Sort by: Cheapest

July 3 - July 6

Cheapest

MDE - Guayaquil

$282

$322

Round trip

July 8 - July 9

MDE - Guayaquil

$274

$325

Round trip

July 10 - July 13

MDE - Guayaquil

$270

$333

Round trip

July 2 - July 5

MDE - Guayaquil

$288

$339

Round trip

July 1 - July 3

MDE - Guayaquil

$288

$340

Round trip

July 3 - July 5

MDE - Guayaquil

$281

$340

Round trip

July 22 - July 24

MDE - Guayaquil

$185

$376

Round trip

July 10 - July 15

MDE - Guayaquil

$188

$386

Round trip

June 18 - June 30

Earliest

MDE - Guayaquil

$330

$388

Round trip

June 19 - June 23

Best

MDE - Guayaquil

$402

$388

Round trip

Unlock all 500+ flight deals to Guayaquil and get alerts when great deals appear

Route Intelligence — 486,190 Searches this Week

Insights for flights from Medellín to Guayaquil

Right now, the cheapest flights from Medellín to Guayaquil are priced below the typical level. Fares for this route typically range from $235–$327, with a median of $247. While new deals appear almost daily for this route, currently 0% of recent fares are classified as a good price.

When is the cheapest time to fly from Medellín to Guayaquil? The most affordable months to fly are June, with a median fare of $245, followed closely by July and May, both showing median fares of $246. These months offer the best opportunities for finding lower prices on this route.

A typical journey from Medellín to Guayaquil takes about 4h 55m, including connections. This duration accounts for the fact that most itineraries connect at least once. Only 13.9% of recent fares are for direct flights from Medellín to Guayaquil, meaning the majority of travelers will have at least one stopover, typically with 1 connection.

The route from Medellín to Guayaquil covers a distance of 1050 km, classifying it as a short-haul flight. This distance means you can expect a relatively quick journey, even with the typical stopovers involved.

How much is a round trip from Medellín to Guayaquil

Regular price: $230 - $297

Prices for flights from Medellín to Guayaquil are currently above the regular range.

The regular price range for this route is between $230 and $297. The current lowest deal is $321 with Avianca, for travel from Jul 3-Jul 6.

now $321

Low $230

High $297

The cheapest time to fly from Medellín to Guayaquil

The cheapest month to fly from MDE to GYE is June, with a median price of $245. The most expensive month is August, with a median price of $370. Prices are generally lower from March to November.

June

Cheapest

Flights from $245

August

Most Expensive

Flights from $370

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Medellín to Guayaquil

Avianca

Last-minute flights going from Medellín to Guayaquil

Thu, Jun 18

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Copa Airlines

$330

$388

One-way

Fri, Jun 19

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Copa Airlines

$404

$388

One-way

Fri, Jun 19

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Copa Airlines

$402

$388

One-way

Fri, Jun 19

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Copa Airlines

$408

$388

One-way

Fri, Jun 19

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$249

$417

One-way

Mon, Jun 22

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$232

$408

One-way

Biggest price drops on these dates for flights from Medellín to Guayaquil

1 night

Jun 19 - Jun 20

$408 → $388

3 nights

Jun 19 - Jun 22

$404 → $388

4 nights

Jun 19 - Jun 23

$402 → $388

2 nights

Aug 19 - Aug 21

$366 → $388

Popular Airports to fly from Medellín to Guayaquil

Medellín - Guayaquil route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Medellín to Guayaquil are below the typical level, with a median price of $247.

📅 Best time to fly

Fly in June for the best prices

Historically, June is the cheapest month to fly from Medellín to Guayaquil, with a median price of $245.

⏱️ Flight duration

Total flight time is 4h 55m

The typical flight duration from Medellín to Guayaquil is 4 hours and 55 minutes, including layovers.

✈️ Airlines & availability

13.9% of deals are direct flights

About 13.9% of deals for this route are direct, with connecting flights having 1 stopover.

🏆 Airline highlight

Avianca offers direct flights

Avianca is one airline that historically offers direct flights from Medellín to Guayaquil.

🎯 Booking tip

Deals are frequent for this route

Deals for flights from Medellín to Guayaquil are frequent, with over 1 deal per day.

Medellín main airports to depart from

José María Córdova International (MDE)

Cheapest

José María Córdova International Airport is a good option for flights from Medellín to Guayaquil.

📍 ~20 km from Medellín city center (reachable by car)

💸 Flights from ~$321

Olaya Herrera (EOH)

Olaya Herrera Airport is an alternative departure point for flights from Medellín to Guayaquil.

📍 ~3 km from Medellín city center (reachable by car)

💸 Flights from ~$471

Guayaquil main airports to arrive at

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International Airport is a convenient arrival option for flights to Guayaquil.

📍 ~5 km from city center (reachable by car)

💸 Flights from ~$322

Airports nearby Guayaquil used as alternative

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International is a major international hub, useful for long-haul flights if Guayaquil is unavailable.

📍 ~400 km from Guayaquil (reachable by car, approx. 7-8 hours travel).

💸 Flights from ~$323

Mariscal Lamar International (CUE)

Mariscal Lamar International is a close domestic alternative with reliable connections to major Ecuadorian cities.

📍 ~135 km from Guayaquil (reachable by car, approx. 3-4 hours travel).

💸 Flights from ~$445

Eloy Alfaro International (MEC)

Eloy Alfaro International is a coastal alternative, useful as a secondary domestic hub with increasing connectivity.

📍 ~180 km from Guayaquil (reachable by car, approx. 3 hours travel).

💸 Flights from ~$367

Cap. FAP Pedro Canga Rodríguez (TBP)

Cap. FAP Pedro Canga Rodríguez is useful for accessing the Peruvian domestic flight network directly.

📍 ~130 km from Guayaquil (requires international border crossing).

💸 Flights from ~$414

FAP Captain Guillermo Concha Iberico International (PIU)

FAP Captain Guillermo Concha Iberico International is a regional hub in Northern Peru, good for connecting via Lima.

📍 ~330 km from Guayaquil (requires international border crossing).

💸 Flights from ~$394

Business & First Class Flight Deals to Guayaquil

47% AI deal score

$1,510

From MDE

Elite

Jun 30

Guayaquil, Ecuador

47% AI deal score

$1,772

From MDE

Elite

Jun 30

Guayaquil, Ecuador

46% AI deal score

$2,096

From MDE

Elite

Jun 30

Guayaquil, Ecuador

46% AI deal score

$2,147

Frequently Asked Questions About Flights to Guayaquil

Historically, the optimal booking window for flights from Medellín to Guayaquil is typically 14-27 days in advance. During this period, the average price was around $255. Booking 0-6 days before departure also showed an average price of $261. However, prices tend to increase for bookings made further out, with flights booked 60+ days in advance averaging $310.

Historically, a good price for a flight from Medellín to Guayaquil is considered to be $235 or less. The median price for this route across the trailing quarter was $247. Flights priced at $327 or more are typically in the higher range for this route.

Historically, June, July, and May have shown the cheapest flights from Medellín to Guayaquil, with median prices of $245, $246, and $246 respectively. The annual median price for this route is $247. While July is one of the cheapest months, it also represents the most expensive month on average, indicating price fluctuations within the month.

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Cheap Flights from Medellín to Guayaquil

Today’s best flight deals from Medellín to Guayaquil

Unlock all 500+ flight deals to Guayaquil and get alerts when great deals appear

Route Intelligence — 486,190 Searches this Week

Insights for flights from Medellín to Guayaquil

How much is a round trip from Medellín to Guayaquil

The cheapest time to fly from Medellín to Guayaquil

Direct flights from Medellín to Guayaquil

Last-minute flights going from Medellín to Guayaquil

Biggest price drops on these dates for flights from Medellín to Guayaquil

Popular Airports to fly from Medellín to Guayaquil

Medellín - Guayaquil route insights

Recent fares are below the typical level

Fly in June for the best prices

Total flight time is 4h 55m

13.9% of deals are direct flights

Avianca offers direct flights

Deals are frequent for this route

Medellín main airports to depart from

Guayaquil main airports to arrive at

Airports nearby Guayaquil used as alternative

Business & First Class Flight Deals to Guayaquil

Best Elite deals to Guayaquil

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Frequently Asked Questions About Flights to Guayaquil

How far in advance should I book a flight from Medellín to Guayaquil?

How far in advance should I book a flight from Medellín to Guayaquil?

What's a cheap fare from Medellín to Guayaquil?