To Panama City

Cheap Flights from Rome to Panama City

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Panama City

Prices updated 24 days ago

486,190 searches this week

171 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)

Today’s best flight deals from Rome to Panama City

Explore current cheapest deals departing from Rome to Panama City

Round trip

Sort by: Cheapest

November 4 - November 9

Cheapest

Best

FCO - Panama City

$1,230

$725

Round trip

November 3 - November 9

Best

FCO - Panama City

$1,212

$728

Round trip

July 16 - July 22

FCO - Panama City

$1,111

$836

Round trip

July 14 - July 20

FCO - Panama City

$1,111

$839

Round trip

July 12 - July 18

FCO - Panama City

$1,122

$1,128

Round trip

June 21 - June 28

Earliest

FCO - Panama City

$1,375

$1,133

Round trip

August 20 - September 16

FCO - Panama City

$1,207

$1,352

Round trip

August 20 - September 13

FCO - Panama City

$1,207

$1,360

Round trip

August 31 - September 5

FCO - Panama City

$1,295

$1,394

Round trip

August 22 - September 5

FCO - Panama City

$1,231

$1,460

Round trip

Unlock all 500+ flight deals to Panama City and get alerts when great deals appear

Route Intelligence — 486,190 Searches this Week

How much is a round trip from Rome to Panama City

Regular price: $1,056 - $1,561

Prices for flights from Rome to Panama City are currently below the regular range.

The regular price range for this route is between $1056 and $1561. The current lowest deal is $725 with Deutsche Luft Hansa, for travel from Nov 4 to Nov 9.

now $725

Low $1,056

High $1,561

The cheapest time to fly from Rome to Panama City

The cheapest month to fly from Rome to Panama City is November, with a median price of $728. The most expensive month is June, with a median price of $3880. Prices are generally lower from August to November.

November

Cheapest

Flights from $728

June

Most Expensive

Flights from $3,880

Jun

Jul

Aug

Sep

Nov

Direct flights from Rome to Panama City

WestJet

Air Transat

Aer Lingus

Lufthansa

Last-minute flights going from Rome to Panama City

Fri, Jun 19

⌛ Last-Minute

FCO - Panama City

Rome (FCO) - Panama City (ECP)

Air Transat, WestJet

$1,425

$1,605

One-way

Fri, Jun 19

⌛ Last-Minute

FCO - Panama City

Rome (FCO) - Panama City (ECP)

Air Transat, WestJet

$1,319

$1,619

One-way

Sun, Jun 21

⌛ Last-Minute

FCO - Panama City

Rome (FCO) - Panama City (ECP)

American Airlines

$1,375

$1,133

One-way

Mon, Jun 22

⌛ Last-Minute

FCO - Panama City

Rome (FCO) - Panama City (ECP)

Finnair

$1,504

$1,901

One-way

Wed, Jun 24

⌛ Last-Minute

FCO - Panama City

Rome (FCO) - Panama City (ECP)

Air Transat, WestJet

$1,313

$1,534

One-way

Tue, Jun 30

⌛ Last-Minute

FCO - Panama City

Rome (FCO) - Panama City (ECP)

Lufthansa, WestJet

$1,217

$3,880

One-way

Biggest price drops on these dates for flights from Rome to Panama City

5 nights

Nov 4 - Nov 9

$1,230 → $725

41%

6 nights

Nov 3 - Nov 9

$1,212 → $728

40%

6 nights

Jul 16 - Jul 22

$1,111 → $836

25%

6 nights

Jul 14 - Jul 20

$1,111 → $839

24%

Popular Airports to fly from Rome to Panama City

Rome - Panama City route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Panama City are currently at $725, below the typical level.

📅 Best time to fly

November is historically cheapest

Historically, November is the cheapest month to fly from Rome to Panama City, with a median price of $728.

⏱️ Flight duration

Connecting flights take 15h 13m

Connecting flights from Rome to Panama City typically take 15 hours and 13 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant for this route, with a median of 1 stopover.

🏆 Airline highlight

Deutsche Luft Hansa offers a recent deal

Deutsche Luft Hansa recently offered a deal for $725 from Rome to Panama City.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Rome to Panama City are historically rare.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Consider FCO for flights from Rome to Panama City, offering a good balance of convenience and value.

📍 ~20 km from Rome city center (reachable by car, bus, or train)

💸 Flights from ~$715

Ciampino–G. B. Pastine International (CIA)

CIA is an alternative departure airport for your journey from Rome to Panama City.

📍 ~15 km from Rome city center (reachable by car or bus)

💸 Flights from ~$715

Panama City main airports to arrive at

Northwest Florida Beaches International (ECP)

Cheapest

Northwest Florida Beaches International Airport is a good choice for reaching Panama City.

📍 ~20 km from Panama City (reachable by car)

💸 Flights from ~$725

Airports nearby Panama City used as alternative

Destin–Fort Walton Beach (VPS)

Cheapest

Consider Destin–Fort Walton Beach for a nearby alternative, offering frequent flight options to Panama City.

📍 ~95 km from Panama City (reachable by car, though traffic on Highway 98 can significantly impact travel time).

💸 Flights from ~$672

Pensacola International (PNS)

Pensacola International is a reliable alternative with superior connectivity and a full range of cabin classes.

📍 ~115 km from Panama City (approximately 1.5 to 2 hours drive).

💸 Flights from ~$728

Tallahassee International (TLH)

Tallahassee International offers consistent regional jet service and is a reasonable driving distance away.

📍 ~160 km from Panama City (located in a different timezone, Eastern Time).

💸 Flights from ~$733

Dothan Regional (DHN)

Dothan Regional provides a simple terminal experience for quick departures, with relatively close proximity.

📍 ~120 km from Panama City.

💸 Flights from ~$3571

Montgomery Regional (MGM)

Montgomery Regional is an alternative for travelers heading north into Alabama, offering additional carrier options.

📍 ~245 km from Panama City.

💸 Flights from ~$1547

Business & First Class Flight Deals to Panama City

Discover luxury on the budget with premium cabin class on flights from Rome to Panama City.

Panama City, United States

66% AI deal score

$13,229

Frequently Asked Questions About Flights to Panama City

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you identify better deals. Setting up price alerts may notify you when fares drop.

Booking flights in advance often provides more options and potentially lower prices. However, last-minute deals can sometimes appear, so it's wise to monitor fares. The optimal booking time can vary depending on various factors.

Comparing nearby airports at both your origin and destination can sometimes reveal more economical flight options. While it may add to travel time, the savings can be significant. Always check ground transportation costs to these alternative airports.

Related routes

Consider alternative routes from Rome

Flights from Rome to Aguadilla Flights from Rome to Akureyri Flights from Rome to Amsterdam Flights from Rome to Anchorage Flights from Rome to Asheville Flights from Rome to Athens Flights from Rome to Bangkok Flights from Rome to Barcelona Flights from Rome to Beijing Flights from Rome to Belfast Flights from Rome to Belgrade Flights from Rome to Bergen

Cheap Flights from Rome to Panama City

Today’s best flight deals from Rome to Panama City

Unlock all 500+ flight deals to Panama City and get alerts when great deals appear

Route Intelligence — 486,190 Searches this Week

How much is a round trip from Rome to Panama City

The cheapest time to fly from Rome to Panama City

Direct flights from Rome to Panama City

Last-minute flights going from Rome to Panama City

Biggest price drops on these dates for flights from Rome to Panama City

Popular Airports to fly from Rome to Panama City

Rome - Panama City route insights

Recent fares are below the typical level

November is historically cheapest

Connecting flights take 15h 13m

Connecting flights are dominant

Deutsche Luft Hansa offers a recent deal

Deals are rare for this route

Rome main airports to depart from

Panama City main airports to arrive at

Airports nearby Panama City used as alternative

Business & First Class Flight Deals to Panama City

Best Elite deals to Panama City

Aug 24

Aug 20

Aug 24

Aug 24

Aug 18

Jul 20

Jul 20

Jul 15

Jul 14

Jul 13

Aug 24

Aug 24

Aug 20

Aug 20

Aug 18

Aug 18

Aug 28

Aug 22

Jul 29

Aug 20

Aug 20

Jul 15

Jul 14

Jul 15

Jul 14

Jul 13

Jul 13

Jul 21

Jul 21

Aug 18

Aug 18

Sep 20

Aug 22

Aug 28

Aug 28

Aug 22

Jul 29

Jul 15

Jul 14

Jul 22

Jul 22

Jul 19

Jul 31

Jul 19

Jul 13

Jul 13

Jul 12

Jul 12

Jul 09

Jul 08

Oct 22

Jul 20

Jun 22

Jul 01

Frequently Asked Questions About Flights to Panama City

How can I find cheap flights from Rome to Panama City?

How can I find cheap flights from Rome to Panama City?

When should I book flights from Rome to Panama City?