To St. Louis

Cheap Flights from Rome to St. Louis

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to St. Louis

Prices updated 24 days ago

486,190 searches this week

171 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)

Today’s best flight deals from Rome to St. Louis

Explore current cheapest deals departing from Rome to St. Louis

Round trip

Sort by: Cheapest

September 21 - September 27

Cheapest

FCO - St. Louis

$922

$834

Round trip

October 1 - October 5

Best

FCO - St. Louis

$1,008

$835

Round trip

September 22 - September 27

FCO - St. Louis

$941

$836

Round trip

October 19 - October 28

FCO - St. Louis

$1,003

$845

Round trip

September 19 - September 27

FCO - St. Louis

$901

$849

Round trip

September 21 - September 26

FCO - St. Louis

$940

$853

Round trip

September 20 - September 26

FCO - St. Louis

$923

$855

Round trip

August 16 - August 30

FCO - St. Louis

$1,039

$897

Round trip

July 13 - July 20

Earliest

FCO - St. Louis

$964

$960

Round trip

August 19 - August 21

FCO - St. Louis

$1,134

$961

Round trip

Unlock all 500+ flight deals to St. Louis and get alerts when great deals appear

Route Intelligence — 486,190 Searches this Week

Insights for flights from Rome to St. Louis

A typical journey from Rome to St. Louis, including connections, takes about 48h 14m. This indicates a significant travel time, primarily due to the nature of the route, which is classified as long-haul, covering a distance of 8131 km.

For travelers seeking cheap flights from Rome to St. Louis, fares right now are below the typical level. Prices for this route typically range from $1095–$1633, with a median of $1239. Currently, no recent fares have been classified as a good price, suggesting that finding exceptional value may require careful timing.

When is the cheapest time to fly from Rome to St. Louis? The data indicates that October is typically the most affordable month, with a median fare of $1136. Following closely are May, with a median fare of $1138, and April, where the median fare is $1161. These months present the best opportunities for lower prices on this route.

Most itineraries from Rome to St. Louis connect at least once. In fact, 0% of recent fares were non-stop flights, meaning you should expect to make connections. For connecting itineraries, the typical number of stopovers is 5, which contributes to the extended overall journey time.

How much is a round trip from Rome to St. Louis

Regular price: $810 - $1,427

Prices for flights from Rome to St. Louis are currently within the regular range.

Regular prices for flights from Rome to St. Louis typically range from $810 to $1427. The current lowest deal is $834 with Iberia Airlines for travel from Sep 21-Sep 27.

now $834

Low $810

High $1,427

The cheapest time to fly from Rome to St. Louis

The cheapest month to fly from Rome to St. Louis is October, with a median price of $1136. The most expensive month is August, with a median price of $1679. Prices are generally lower from April to October.

October

Cheapest

Flights from $1,136

August

Most Expensive

Flights from $1,679

Apr

May

Jun

Jul

Aug

Sep

Oct

Direct flights from Rome to St. Louis

Alaska Airlines, Inc.

Iberia Airlines

Alitalia

British Airways

Last-minute flights going from Rome to St. Louis

Fri, Jun 19

⌛ Last-Minute

FCO - St. Louis

Rome (FCO) - St. Louis (STL)

Aer Lingus

$1,185

$2,339

One-way

Fri, Jun 19

⌛ Last-Minute

FCO - St. Louis

Rome (FCO) - St. Louis (STL)

Aer Lingus

$1,203

$2,339

One-way

Tue, Jun 23

⌛ Last-Minute

FCO - St. Louis

Rome (FCO) - St. Louis (STL)

British Airways

$1,060

$1,238

One-way

Wed, Jul 1

⌛ Last-Minute

FCO - St. Louis

Rome (FCO) - St. Louis (STL)

Deutsche Luft Hansa

$1,102

$1,118

One-way

Mon, Jul 6

⌛ Last-Minute

FCO - St. Louis

Rome (FCO) - St. Louis (STL)

Iberia Airlines

$934

$966

One-way

Wed, Jul 8

⌛ Last-Minute

FCO - St. Louis

Rome (FCO) - St. Louis (STL)

Alaska Airlines, Inc.

$982

$1,765

One-way

Biggest price drops on these dates for flights from Rome to St. Louis

4 nights

Oct 1 - Oct 5

$1,008 → $835

17%

2 nights

Aug 19 - Aug 21

$1,134 → $961

15%

9 nights

Oct 19 - Oct 28

$1,003 → $845

16%

14 nights

Aug 16 - Aug 30

$1,039 → $897

14%

Popular Airports to fly from Rome to St. Louis

Rome - St. Louis route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to St. Louis are below the typical level, with a median price of $1239.

📅 Best time to fly

October is historically the cheapest month to fly

Historically, October is the cheapest month to fly from Rome to St. Louis, with a median price of $1136.

⏱️ Flight duration

Flights typically take 48h 14m

Flights from Rome to St. Louis typically take 48h 14m, covering a long-haul distance of 8131 km.

✈️ Airlines & availability

Connecting flights are dominant for this route

Connecting flights are dominant for this route, with a median of 5 stopovers.

🏆 Airline highlight

Iberia Airlines offers a recent deal for $834

Iberia Airlines has a recent deal for $834 from Rome to St. Louis, departing September 21.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Rome to St. Louis are rare, with about 0.07 deals per day.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport for flights from Rome to St. Louis.

📍 ~25 km from Rome city center (reachable by car or train).

💸 Flights from ~$834

Ciampino–G. B. Pastine International (CIA)

Ciampino–G. B. Pastine International is another option for flights from Rome to St. Louis.

📍 ~15 km from Rome city center (reachable by car or train).

💸 Flights from ~$918

St. Louis main airports to arrive at

St. Louis Lambert International (STL)

Cheapest

St. Louis Lambert International is a good arrival choice for flights from Rome to St. Louis.

📍 ~20 km from St. Louis (reachable by car)

💸 Flights from ~$906

Airports nearby St. Louis used as alternative

MidAmerica St. Louis (BLV)

MidAmerica St. Louis (BLV) can be a useful alternative for budget routes, especially for travelers on the Illinois side of the metro area.

📍 ~50 km from St. Louis (reachable by car)

💸 Flights from ~$858

Columbia Regional (COU)

Columbia Regional (COU) offers a full range of cabin classes and serves as a reliable regional hub.

📍 ~170 km from St. Louis (reachable by car)

💸 Flights from ~$1065

Abraham Lincoln Capital (SPI)

Cheapest

Abraham Lincoln Capital (SPI) provides consistent regional service with Business class availability.

📍 ~150 km from St. Louis (reachable by car)

💸 Flights from ~$713

General Wayne A. Downing Peoria International (PIA)

General Wayne A. Downing Peoria International (PIA) is a larger regional airport offering multiple cabin classes.

📍 ~230 km from St. Louis (reachable by car)

💸 Flights from ~$880

Central Illinois Regional (BMI)

Central Illinois Regional (BMI) is an alternative for travelers willing to drive into Central Illinois.

📍 ~250 km from St. Louis (reachable by car)

💸 Flights from ~$1010

Business & First Class Flight Deals to St. Louis

76% AI deal score

$4,290

From FCO

Elite

Jul 15

St. Louis, United States

76% AI deal score

$4,291

From FCO

Elite

Jul 18

St. Louis, United States

76% AI deal score

$4,367

$4,297

Save $70

From FCO

Elite

Jul 15

St. Louis, United States

76% AI deal score

$4,307

From FCO

Elite

Jul 07

St. Louis, United States

76% AI deal score

$4,417

From FCO

Elite

Jul 30

St. Louis, United States

76% AI deal score

$4,520

From FCO

St. Louis, United States

75% AI deal score

$4,261

From FCO

Elite

Jul 23

St. Louis, United States

75% AI deal score

$4,516

From FCO

Elite

Jul 23

St. Louis, United States

75% AI deal score

$4,532

From FCO

Elite

Jul 14

St. Louis, United States

75% AI deal score

$4,548

From FCO

Elite

Jul 01

St. Louis, United States

75% AI deal score

St. Louis, United States

68% AI deal score

$41,367

From FCO

Elite

Oct 27

St. Louis, United States

68% AI deal score

$41,666

Frequently Asked Questions About Flights to St. Louis

Finding affordable flights often involves comparing prices across various platforms. Using flight comparison sites can help you see different options in one place. Being flexible with your travel dates and times may also lead to better deals.

Booking flights in advance can often secure better prices, though the ideal booking window can vary. Prices may fluctuate, so monitoring fares over time can be beneficial. Generally, last-minute bookings can sometimes be more expensive.

Comparing nearby airports can sometimes reveal more economical flight options. While it might add to your ground travel, the potential savings on airfare could be significant. Always consider the total cost and convenience when evaluating this option.

Related routes

Consider alternative routes from Rome

Flights from Rome to Aguadilla Flights from Rome to Akureyri Flights from Rome to Amsterdam Flights from Rome to Anchorage Flights from Rome to Asheville Flights from Rome to Athens Flights from Rome to Bangkok Flights from Rome to Barcelona Flights from Rome to Beijing Flights from Rome to Belfast Flights from Rome to Belgrade Flights from Rome to Bergen