Cheap Flights from Santiago de Chile to Panama City
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Deals from
Santiago de Chile
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Prices updated 24 days ago
486,190 searches this week
171 airlines compared
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Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)
Today’s best flight deals from Santiago de Chile to Panama City
Explore current cheapest deals departing from Santiago de Chile to Panama City
Round trip
Sort by: Cheapest
June 30 - July 6
SCL - Panama
$437
$610
Round trip
July 14 - July 21
SCL - Panama
$510
$620
Round trip
July 15 - July 23
SCL - Panama
$502
$620
Round trip
July 18 - July 24
SCL - Panama
$510
$620
Round trip
July 18 - July 29
SCL - Panama
$488
$620
Round trip
July 19 - July 24
SCL - Panama
$520
$620
Round trip
July 19 - July 25
SCL - Panama
$511
$620
Round trip
July 20 - July 25
SCL - Panama
$513
$620
Round trip
July 21 - July 26
SCL - Panama
$513
$620
Round trip
July 21 - July 29
SCL - Panama
$496
$620
Round trip
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Route Intelligence — 486,190 Searches this Week
Insights for flights from Santiago de Chile to Panama City
How much is a round trip from Santiago de Chile to Panama City
Regular price: $383 - $572
Prices for flights from Santiago de Chile to Panama are currently above the regular range.
Regularly, flights from Santiago de Chile to Panama range from $383 to $572. The current lowest deal is $610 on Kayak, for travel from Jun 30-Jul 6.
now $610
Low $383
High $572
The cheapest time to fly from Santiago de Chile to Panama City
The cheapest month to fly from SCL to ECP is February, with a median price of $737. The most expensive month is May, with a median price of $1214. Prices are generally lower from January to November.
February
Flights from $737
May
Flights from $1,214
Direct flights from Santiago de Chile to Panama City
United Airlines
Last-minute flights going from Santiago de Chile to Panama City
Tue, Jun 30
SCL - Panama
Santiago de Chile (SCL) - Panama (PTY)
$437
$610
One-way
Fri, Jul 3
SCL - Panama City
Santiago de Chile (SCL) - Panama City (ECP)
United Airlines
$785
$1,360
One-way
Sun, Jul 5
SCL - Panama City
Santiago de Chile (SCL) - Panama City (ECP)
United Airlines
$784
$1,258
One-way
Mon, Jul 13
SCL - Panama City
Santiago de Chile (SCL) - Panama City (ECP)
United Airlines
$769
$1,049
One-way
Tue, Jul 14
SCL - Panama
Santiago de Chile (SCL) - Panama (PTY)
$510
$620
One-way
Tue, Jul 14
SCL - Panama City
Santiago de Chile (SCL) - Panama City (ECP)
United Airlines
$769
$1,200
One-way
Biggest price drops on these dates for flights from Santiago de Chile to Panama City
Sep 30 - Oct 6
$861 → $620
28%
Sep 28 - Oct 4
$840 → $620
26%
Sep 22 - Sep 26
$829 → $620
25%
Sep 18 - Sep 23
$822 → $620
25%
Popular Airports to fly from Santiago de Chile to Panama City
Santiago de Chile - Panama City route insights
💸 Price insights
Recent fares are below the typical level
Recent fares from Santiago de Chile to Panama City are below the typical level, at $610.
📅 Best time to fly
Fly in February for the best prices
Historically, February offers the lowest median price at $737 for Santiago de Chile to Panama City.
⏱️ Flight duration
Connecting flights take 27h 36m
Flights from Santiago de Chile to Panama City typically involve connections, with a median duration of 27h 36m.
✈️ Airlines & availability
Connecting flights are dominant
There are no direct flights; all routes from Santiago de Chile to Panama City are connecting.
🏆 Airline highlight
United Airlines offers connecting deals
United Airlines has historically offered connecting flights from Santiago de Chile to Panama City.
🎯 Booking tip
Deals are frequent for this route
Deals for flights from Santiago de Chile to Panama City are frequent, appearing 0.8 times per day.
Santiago de Chile main airports to depart from
Comodoro Arturo Merino Benítez International (SCL)
Fly from Santiago de Chile to Panama City with competitive prices from Comodoro Arturo Merino Benítez International Airport.
📍 ~15 km from city center (reachable by car)
💸 Flights from ~$610
Panama City main airports to arrive at
Northwest Florida Beaches International (ECP)
Northwest Florida Beaches International Airport is a good arrival choice for flights to Panama City.
📍 ~25 km from Panama City (reachable by car)
💸 Flights from ~$878
Airports nearby Panama City used as alternative
Destin–Fort Walton Beach (VPS)
Destin–Fort Walton Beach Airport can be a useful alternative due to its proximity and frequent flight options.
📍 ~100 km from Panama City (traffic on Highway 98 can impact travel time).
💸 Flights from ~$705
Pensacola International (PNS)
Pensacola International Airport is a reliable alternative with superior connectivity and a full range of cabin classes.
📍 ~120 km from Panama City (approximately 1.5 to 2 hours drive).
💸 Flights from ~$685
Tallahassee International (TLH)
Tallahassee International Airport offers consistent regional jet service and reasonable driving distance via I-10.
📍 ~120 km from Panama City (located in a different timezone).
💸 Flights from ~$685
Dothan Regional (DHN)
Dothan Regional Airport provides a simple terminal experience for quick departures, with relatively close proximity.
📍 ~100 km from Panama City.
💸 Flights from ~$2286
Montgomery Regional (MGM)
Montgomery Regional Airport offers additional carrier options for travelers heading north into Alabama.
📍 ~240 km from Panama City.
💸 Flights from ~$1457
Business & First Class Flight Deals to Panama City
Discover luxury on the budget with premium cabin class on flights from Santiago de Chile to Panama City.
Elite
Best Elite deals to Panama City
Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.
From SCL
Elite
Jul 19
Panama City, United States
69% AI deal score
$7,932
From SCL
Elite
Jul 20
Panama City, United States
69% AI deal score
$8,007
From SCL
Elite
Jul 13
Panama City, United States
67% AI deal score
$9,396
From SCL
Elite
Jul 14
Panama City, United States
67% AI deal score
$6,734