To Santiago de Chile

Cheap Flights from Santo Domingo to Santiago de Chile

Browse current best options from Santo Domingo. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Santo Domingo

RatePunk searches hundreds of travel sites at once for deals on flights to Santiago de Chile

Prices updated 24 days ago

486,190 searches this week

171 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)

Today’s best flight deals from Santo Domingo to Santiago de Chile

Explore current cheapest deals departing from Santo Domingo to Santiago de Chile

Round trip

Sort by: Cheapest

July 9 - July 24

Cheapest

Earliest

SDQ - Santiago de Chile

$484

$562

Round trip

October 3 - October 25

SDQ - Santiago de Chile

$582

$640

Round trip

September 12 - September 22

SDQ - Santiago de Chile

$536

$644

Round trip

August 21 - August 28

Best

SDQ - Santiago de Chile

$496

$648

Round trip

August 22 - August 26

Best

SDQ - Santiago de Chile

$512

$648

Round trip

August 19 - August 26

Best

SDQ - Santiago de Chile

$499

$648

Round trip

August 20 - August 27

Best

SDQ - Santiago de Chile

$496

$648

Round trip

August 24 - August 30

Best

SDQ - Santiago de Chile

$495

$648

Round trip

August 20 - August 22

Best

SDQ - Santiago de Chile

$517

$648

Round trip

August 17 - August 25

Best

SDQ - Santiago de Chile

$491

$648

Round trip

Unlock all 500+ flight deals to Santiago de Chile and get alerts when great deals appear

Route Intelligence — 486,190 Searches this Week

Insights for flights from Santo Domingo to Santiago de Chile

Flights from Santo Domingo to Santiago de Chile cover a substantial distance of 5,764 km, classifying this as a long-haul route. This means you can expect a significant travel time, often involving connections, to reach your destination.

For those seeking cheap flights from Santo Domingo to Santiago de Chile, fares typically range from $411–$730, with a median of $450. Right now, fares are near the typical level for this route. New deals appear almost daily, suggesting frequent opportunities to find competitive prices.

If you are wondering when is the cheapest time to fly from Santo Domingo to Santiago de Chile, February stands out as the most affordable month, with a median fare of $384. December also offers relatively lower prices, with a median of $411, followed by June at a median of $422.

Most itineraries on this route connect at least once, as direct flights from Santo Domingo to Santiago de Chile are not common. When connections are necessary, the typical number of stopovers is 1.

A typical journey from Santo Domingo to Santiago de Chile, including connections, takes approximately 16h 0m. This duration reflects the long-haul nature of the route and the common need for at least one stopover.

How much is a round trip from Santo Domingo to Santiago de Chile

Regular price: $428 - $762

Prices for flights from Santo Domingo to Santiago de Chile are currently within the regular range.

The regular price range for flights from Santo Domingo to Santiago de Chile is between $428 and $762. The current lowest deal is $562 with Maersk Air. This price is for travel from Jul 9-Jul 24.

now $562

Low $428

High $762

The cheapest time to fly from Santo Domingo to Santiago de Chile

The cheapest month to fly from Santo Domingo to Santiago is February, with a median price of $384. The most expensive month is July, with a median price of $917. Prices are generally lower from January to December.

February

Cheapest

Flights from $384

July

Most Expensive

Flights from $917

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Santo Domingo to Santiago de Chile

Avianca

Copa Airlines

Maersk Air

Last-minute flights going from Santo Domingo to Santiago de Chile

Mon, Jun 22

⌛ Last-Minute

SDQ - Santiago de Chile

Santo Domingo (SDQ) - Santiago de Chile (SCL)

Copa Airlines

$633

$681

One-way

Tue, Jun 23

⌛ Last-Minute

SDQ - Santiago de Chile

Santo Domingo (SDQ) - Santiago de Chile (SCL)

Copa Airlines

$574

$655

One-way

Sun, Jul 5

⌛ Last-Minute

SDQ - Santiago de Chile

Santo Domingo (SDQ) - Santiago de Chile (SCL)

Copa Airlines

$505

$705

One-way

Wed, Jul 8

⌛ Last-Minute

SDQ - Santiago de Chile

Santo Domingo (SDQ) - Santiago de Chile (SCL)

Copa Airlines

$504

$744

One-way

Thu, Jul 9

⌛ Last-Minute

SDQ - Santiago de Chile

Santo Domingo (SDQ) - Santiago de Chile (SCL)

Maersk Air

$484

$562

One-way

Thu, Jul 9

⌛ Last-Minute

SDQ - Santiago de Chile

Santo Domingo (SDQ) - Santiago de Chile (SCL)

Copa Airlines

$493

$654

One-way

Biggest price drops on these dates for flights from Santo Domingo to Santiago de Chile

3 nights

Jun 22 - Jun 25

$633 → $681

22 nights

Oct 3 - Oct 25

$582 → $640

10%

3 nights

Oct 1 - Oct 4

$626 → $684

6 nights

Oct 15 - Oct 21

$632 → $693

10%

Popular Airports to fly from Santo Domingo to Santiago de Chile

Santo Domingo - Santiago de Chile route insights

💸 Price insights

Recent fares are near the typical level

Recent fares from Santo Domingo to Santiago de Chile are near the typical level, at $562.

📅 Best time to fly

February is historically the cheapest month to fly

Historically, February is the cheapest month to fly from Santo Domingo to Santiago de Chile, at $384.

⏱️ Flight duration

Flights are typically 16h 0m connecting

The typical flight duration from Santo Domingo to Santiago de Chile is 16h 0m, with 1 stopover.

✈️ Airlines & availability

Frequent deals from Santo Domingo to Santiago de Chile

Deals are frequent, with over 1 deal per day historically available from Santo Domingo to Santiago de Chile.

🏆 Airline highlight

Maersk Air offers deals from Santo Domingo to Santiago de Chile

Maersk Air has offered deals on this route historically, with a median price of $562.

🎯 Booking tip

Consider flying in February for better prices

Historically, February offers the lowest median price at $384. July is typically the most expensive month.

Santo Domingo main airports to depart from

Las Américas International (SDQ)

Cheapest

Las Américas International is a key option for flights from Santo Domingo to Santiago de Chile.

📍 ~30 km from Santo Domingo city center (reachable by car)

💸 Flights from ~$562

La Isabela International (JBQ)

La Isabela International provides an alternative departure point for your trip to Santiago de Chile.

📍 ~15 km from Santo Domingo city center (reachable by car)

💸 Flights from ~$984

Santiago de Chile main airports to arrive at

Comodoro Arturo Merino Benítez International (SCL)

Cheapest

Fly into SCL to arrive directly in Santiago de Chile, a convenient entry point for your trip.

📍 ~15 km from city center (reachable by car)

💸 Flights from ~$527

Airports nearby Santiago de Chile used as alternative

Governor Francisco Gabrielli International (MDZ)

Consider this airport for its proximity and robust flight schedules, despite requiring an international border crossing into Argentina.

📍 ~180 km from Santiago de Chile (reachable by car)

💸 Flights from ~$641

Carriel Sur International (CCP)

This major domestic alternative within Chile avoids international border formalities and offers strong connectivity.

📍 ~420 km from Santiago de Chile (reachable by car)

💸 Flights from ~$730

La Florida (LSC)

A primary domestic alternative north of Santiago, this airport requires no border crossing for Chilean residents or visitors.

📍 ~470 km from Santiago de Chile (reachable by car)

💸 Flights from ~$720

Ingeniero Aeronáutico Ambrosio L.V. Taravella International (COR)

Cheapest

This major international hub offers diverse airline options and excellent connectivity for long-haul itineraries.

📍 ~700 km from Santiago de Chile (reachable by car)

💸 Flights from ~$624

La Araucanía International (ZCO)

A modern international-standard facility in southern Chile, providing a reliable domestic alternative with consistent service.

📍 ~670 km from Santiago de Chile (reachable by car)

💸 Flights from ~$744

Business & First Class Flight Deals to Santiago de Chile

Discover luxury on the budget with premium cabin class on flights from Santo Domingo to Santiago de Chile.

Elite

Best Elite deals to Santiago de Chile

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

94% AI deal score

$4,037

$2,056

Save $1,981

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

94% AI deal score

$4,003

$2,056

Save $1,947

From SDQ

Elite

Jul 13

Santiago de Chile, Chile

94% AI deal score

$4,188

$2,074

Save $2,114

From SDQ

Elite

Jul 13

Santiago de Chile, Chile

94% AI deal score

$4,127

$2,074

Save $2,053

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

94% AI deal score

$4,681

$2,323

Save $2,358

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,102

$2,175

Save $1,927

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,102

$2,175

Save $1,927

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$3,978

$2,215

Save $1,763

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$3,955

$2,215

Save $1,740

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$4,001

$2,215

Save $1,786

From SDQ

Elite

Jul 31

Santiago de Chile, Chile

93% AI deal score

$3,985

$2,216

Save $1,769

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$3,903

$2,216

Save $1,687

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$4,002

$2,216

Save $1,786

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$3,932

$2,216

Save $1,716

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$3,974

$2,216

Save $1,758

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

93% AI deal score

$4,211

$2,224

Save $1,987

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

93% AI deal score

$4,110

$2,224

Save $1,886

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

93% AI deal score

$4,193

$2,224

Save $1,969

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

93% AI deal score

$4,110

$2,224

Save $1,886

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,119

$2,237

Save $1,882

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,136

$2,239

Save $1,897

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,102

$2,239

Save $1,863

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,102

$2,239

Save $1,863

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

93% AI deal score

$4,185

$2,253

Save $1,932

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,138

$2,278

Save $1,860

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,102

$2,278

Save $1,824

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,142

$2,278

Save $1,864

From SDQ

Elite

Jul 19

Santiago de Chile, Chile

93% AI deal score

$4,196

$2,284

Save $1,912

From SDQ

Elite

Jul 19

Santiago de Chile, Chile

93% AI deal score

$4,136

$2,286

Save $1,850

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

93% AI deal score

$4,110

$2,286

Save $1,824

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

93% AI deal score

$4,558

$2,340

Save $2,218

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

92% AI deal score

$3,971

$2,253

Save $1,718

From SDQ

Elite

Jul 11

Santiago de Chile, Chile

92% AI deal score

$3,995

$2,253

Save $1,742

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

92% AI deal score

$4,009

$2,284

Save $1,725

From SDQ

Elite

Jul 19

Santiago de Chile, Chile

92% AI deal score

$4,049

$2,286

Save $1,763

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

92% AI deal score

$4,003

$2,286

Save $1,717

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

92% AI deal score

$3,998

$2,286

Save $1,712

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

92% AI deal score

$4,011

$2,286

Save $1,725

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

92% AI deal score

$3,986

$2,286

Save $1,700

From SDQ

Elite

Jul 19

Santiago de Chile, Chile

92% AI deal score

$4,014

$2,286

Save $1,728

From SDQ

Elite

Jun 23

Santiago de Chile, Chile

92% AI deal score

$4,102

$2,303

Save $1,799

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

92% AI deal score

$4,110

$2,325

Save $1,785

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

92% AI deal score

$4,110

$2,325

Save $1,785

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

92% AI deal score

$4,117

$2,325

Save $1,792

From SDQ

Elite

Jun 25

Santiago de Chile, Chile

92% AI deal score

$4,003

$2,327

Save $1,676

From SDQ

Elite

Jun 25

Santiago de Chile, Chile

92% AI deal score

$4,003

$2,329

Save $1,674

From SDQ

Elite

Jun 25

Santiago de Chile, Chile

92% AI deal score

$4,019

$2,329

Save $1,690

From SDQ

Elite

Jun 25

Santiago de Chile, Chile

92% AI deal score

$4,003

$2,329

Save $1,674

From SDQ

Elite

Jun 25

Santiago de Chile, Chile

92% AI deal score

$4,009

$2,329

Save $1,680

From SDQ

Elite

Jun 25

Santiago de Chile, Chile

92% AI deal score

$4,035

$2,329

Save $1,706

From SDQ

Elite

Jul 19

Santiago de Chile, Chile

92% AI deal score

$4,214

$2,350

Save $1,864

From SDQ

Elite

Jul 14

Santiago de Chile, Chile

92% AI deal score

$4,010

$2,350

Save $1,660

From SDQ

Elite

Jun 19

Santiago de Chile, Chile

92% AI deal score

$4,276

$2,387

Save $1,889

From SDQ

Elite

Aug 19

Santiago de Chile, Chile

91% AI deal score

$3,885

$2,473

Save $1,412

From SDQ

Elite

Nov 10

Santiago de Chile, Chile

80% AI deal score

$2,349

$2,084

Save $265

From SDQ

Elite

Nov 24

Santiago de Chile, Chile

79% AI deal score

$2,330

$2,140

Save $190

From SDQ

Elite

Nov 09

Santiago de Chile, Chile

79% AI deal score

$2,352

$2,166

Save $186

From SDQ

Elite

Nov 08

Santiago de Chile, Chile

78% AI deal score

$2,351

$2,170

Save $181

From SDQ

Elite

Nov 18

Santiago de Chile, Chile

77% AI deal score

$2,335

$2,245

Save $90

From SDQ

Elite

Nov 11

Santiago de Chile, Chile

77% AI deal score

$2,349

$2,254

Save $95

From SDQ

Elite

Nov 28

Santiago de Chile, Chile

76% AI deal score

$2,331

$2,299

Save $32

From SDQ

Elite

Nov 01

Santiago de Chile, Chile

76% AI deal score

$2,354

$2,301

Save $53

From SDQ

Elite

Nov 15

Santiago de Chile, Chile

76% AI deal score

$2,369

From SDQ

Elite

Dec 05

Santiago de Chile, Chile

75% AI deal score

$2,215

From SDQ

Elite

Dec 06

Santiago de Chile, Chile

75% AI deal score

$2,257

From SDQ

Elite

Aug 11

Santiago de Chile, Chile

75% AI deal score

$2,302

From SDQ

Elite

Nov 01

Santiago de Chile, Chile

75% AI deal score

$2,443

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,222

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,226

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,226

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,236

From SDQ

Elite

Dec 02

Santiago de Chile, Chile

74% AI deal score

$2,246

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,251

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,255

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,256

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,263

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,267

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,268

From SDQ

Elite

Oct 31

Santiago de Chile, Chile

74% AI deal score

$2,287

From SDQ

Elite

Oct 27

Santiago de Chile, Chile

74% AI deal score

$2,313

From SDQ

Elite

Oct 31

Santiago de Chile, Chile

74% AI deal score

$2,339

From SDQ

Elite

Oct 31

Santiago de Chile, Chile

74% AI deal score

$2,343

From SDQ

Elite

Oct 31

Santiago de Chile, Chile

74% AI deal score

$2,343

From SDQ

Elite

Oct 31

Santiago de Chile, Chile

74% AI deal score

$2,343

From SDQ

Elite

Oct 31

Santiago de Chile, Chile

74% AI deal score

$2,429

From SDQ

Elite

Jun 21

Santiago de Chile, Chile

70% AI deal score

$5,829

From SDQ

Elite

Jun 21

Santiago de Chile, Chile

70% AI deal score

$5,979

From SDQ

Elite

Jun 21

Santiago de Chile, Chile

69% AI deal score

$5,904

Frequently Asked Questions About Flights to Santiago de Chile

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking in advance, typically several weeks or months, can often lead to better prices. However, last-minute deals sometimes appear, so it's wise to monitor fares. Prices can fluctuate, so there isn't one single best time to book.

Comparing nearby airports can sometimes offer more flight options or different pricing. While it may add to your travel time, the potential savings could be significant. Always factor in ground transportation costs and convenience when considering this option.

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