Cheap Flights from Quito to Panama City
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Prices updated 24 days ago
486,190 searches this week
171 airlines compared
80%+ AI score for best value
Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)
Today’s best flight deals from Quito to Panama City
Explore current cheapest deals departing from Quito to Panama City
Round trip
Sort by: Cheapest
June 23 - June 27
UIO - Panama
$306
$345
Round trip
June 24 - June 30
UIO - Panama
$277
$345
Round trip
July 1 - July 4
UIO - Panama
$301
$345
Round trip
July 1 - July 5
UIO - Panama
$301
$345
Round trip
July 1 - July 10
UIO - Panama
$272
$345
Round trip
July 2 - July 4
UIO - Panama
$288
$345
Round trip
July 2 - July 5
UIO - Panama
$288
$345
Round trip
July 3 - July 5
UIO - Panama
$288
$345
Round trip
July 3 - July 7
UIO - Panama
$288
$345
Round trip
July 4 - July 14
UIO - Panama
$257
$345
Round trip
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Route Intelligence — 486,190 Searches this Week
Insights for flights from Quito to Panama City
How much is a round trip from Quito to Panama City
Regular price: $249 - $363
Prices for flights from Quito to Panama are currently within the regular range.
The regular price range for flights from Quito to Panama is between $249 and $363. The current lowest deal is $345, available through Kayak for travel from June 23 to June 27.
now $345
Low $249
High $363
The cheapest time to fly from Quito to Panama City
The cheapest month to fly from UIO to ECP is November, with a median price of $548. The most expensive month is April, with a median price of $1265. Prices are generally lower from January to December.
November
Flights from $548
April
Flights from $1,265
Direct flights from Quito to Panama City
Copa Airlines
Last-minute flights going from Quito to Panama City
Fri, Jun 19
UIO - Panama City
Quito (UIO) - Panama City (ECP)
Deutsche Luft Hansa
$662
$1,467
One-way
Fri, Jun 19
UIO - Panama City
Quito (UIO) - Panama City (ECP)
United Airlines
$753
$1,469
One-way
Sat, Jun 20
UIO - Panama City
Quito (UIO) - Panama City (ECP)
Deutsche Luft Hansa
$679
$1,467
One-way
Sun, Jun 21
UIO - Panama City
Quito (UIO) - Panama City (ECP)
United Airlines
$752
$1,453
One-way
Tue, Jun 23
UIO - Panama
Quito (UIO) - Panama (PTY)
$306
$345
One-way
Wed, Jun 24
UIO - Panama
Quito (UIO) - Panama (PTY)
$277
$345
One-way
Biggest price drops on these dates for flights from Quito to Panama City
Jul 17 - Jul 22
$377 → $345
9%
Jul 17 - Jul 24
$373 → $345
8%
Jul 17 - Jul 20
$384 → $358
7%
Jul 17 - Jul 19
$383 → $358
7%
Popular Airports to fly from Quito to Panama City
Quito - Panama City route insights
💸 Price insights
Recent fares are below the typical level
Recent fares for Quito to Panama City are around $345, which is below the typical level.
📅 Best time to fly
November is historically cheapest at $548
Historically, November is the cheapest month to fly from Quito to Panama City, with a median price of $548.
⏱️ Flight duration
Connecting flights average 21h 47m
Flights from Quito to Panama City typically involve connections, with an average total travel time of 21h 47m.
✈️ Airlines & availability
Connecting flights are dominant
There are no direct flights available; connecting flights are the only option for this route.
🏆 Airline highlight
Copa Airlines offers connecting flights
Copa Airlines is one of the carriers offering connecting flights on the Quito to Panama City route.
🎯 Booking tip
Deals appear regularly for this route
Deals for flights from Quito to Panama City appear regularly, about 0.47 deals per day.
Quito main airports to depart from
Mariscal Sucre International (UIO)
Mariscal Sucre International Airport is a good option for flights from Quito to Panama City.
📍 ~15 km from Quito (reachable by car)
💸 Flights from ~$345
Panama City main airports to arrive at
Northwest Florida Beaches International (ECP)
Northwest Florida Beaches International Airport is a convenient arrival airport for Panama City.
📍 ~20 km from city center (reachable by car)
💸 Flights from ~$896
Airports nearby Panama City used as alternative
Destin–Fort Walton Beach (VPS)
Destin–Fort Walton Beach is a useful alternative arrival airport with frequent flight options.
📍 ~100 km from Panama City (traffic on Highway 98 can significantly impact travel time).
💸 Flights from ~$606
Pensacola International (PNS)
Pensacola International is a reliable alternative arrival airport with superior connectivity and major carrier networks.
📍 ~120 km from Panama City (approximately 1.5 to 2 hours drive).
💸 Flights from ~$549
Tallahassee International (TLH)
Tallahassee International is a secondary option for arrivals, offering consistent regional jet service.
📍 ~140 km from Panama City (located in a different timezone).
💸 Flights from ~$632
Dothan Regional (DHN)
Dothan Regional is a niche alternative arrival airport with a simple terminal experience.
📍 ~110 km from Panama City (very limited flight schedule).
💸 Flights from ~$2190
Montgomery Regional (MGM)
Montgomery Regional provides additional carrier options for travelers heading north into Alabama.
📍 ~240 km from Panama City (significant driving distance).
💸 Flights from ~$1383
Business & First Class Flight Deals to Panama City
Discover luxury on the budget with premium cabin class on flights from Quito to Panama City.
Elite
Best Elite deals to Panama City
Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.
From UIO
Elite
Jul 02
Panama City, United States
69% AI deal score
$3,578
From UIO
Elite
Jul 07
Panama City, United States
69% AI deal score
$3,647
From UIO
Elite
Jul 02
Panama City, United States
68% AI deal score
$3,750
From UIO
Elite
Jul 07
Panama City, United States
68% AI deal score
$3,928
From UIO
Elite
Jul 02
Panama City, United States
66% AI deal score
$5,153
From UIO
Elite
Jul 07
Panama City, United States
66% AI deal score
$5,222