Are direct flights from Quito to Panama City always the best option?

Direct flights offer convenience and save time, but they are not always the most budget-friendly choice. Flights with layovers can often be cheaper, especially if you are willing to spend more time in transit. Consider your priorities for cost versus travel duration when making your decision.

Can flexible travel dates help on Quito to Panama City flights?

Yes, being flexible with your travel dates can often lead to finding more affordable flights. Prices can vary significantly between different days of the week or even within the same week. Using a flexible date search tool can help you identify the cheapest days to fly.

What extra costs should I check before booking Quito to Panama City flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Understanding these additional fees can help you calculate the true total cost of your journey.

Flights From Quito

To Panama City

Cheap Flights from Quito to Panama City

Browse current best options from Quito. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Quito

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Prices updated 2 days ago

402 airlines compared

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Fares are subject to change and may not be available for all dates. (Data last updated Jul 12, 2026.)

Today’s best flight deals from Quito to Panama City

Explore current cheapest deals departing from Quito to Panama City

Round trip

Sort by: Cheapest

July 28 - August 1

Cheapest

Best

UIO - Panama

$406

$323

Round trip

August 13 - August 16

Cheapest

UIO - Panama

$374

$323

Round trip

December 24 - January 2

Cheapest

Best

UIO - Panama

$406

$323

Round trip

December 26 - January 2

Cheapest

Best

UIO - Panama

$412

$323

Round trip

December 25 - January 2

UIO - Panama

$407

$333

Round trip

July 23 - July 29

Earliest

UIO - Panama

$287

$334

Round trip

July 24 - July 26

UIO - Panama

$307

$334

Round trip

July 24 - July 27

UIO - Panama

$307

$334

Round trip

July 24 - July 29

UIO - Panama

$292

$334

Round trip

July 25 - July 28

UIO - Panama

$304

$334

Round trip

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Quito to Panama City: Overview

Insights for flights from Quito to Panama City

For cheap flights from Quito to Panama City, fares typically range from $879–$1454, with a median of $1144. Right now, current fares are below the typical level, offering a more favorable price point for travelers. However, 0% of recent fares were classified as a good price, indicating that finding exceptionally low prices on this route can be challenging.

If you are looking for the cheapest time to fly from Quito to Panama City, the data indicates that November is typically the most affordable month, with a median fare of $548. Following closely, February also offers competitive pricing, with a median fare of $553. December is another relatively inexpensive option, with a median fare of $560.

When flying from Quito to Panama City, most itineraries connect at least once, as 0% of recent fares were for non-stop flights. For itineraries that include connections, the typical number of stopovers is 3, which can significantly extend travel time.

A typical journey from Quito to Panama City takes approximately 21h 47m, including connections. This duration reflects the prevalence of connecting flights on this route, as direct options are not commonly available. Travelers should account for this extended travel time when planning their trip.

The route from Quito to Panama City covers a distance of 3480 km, classifying it as a medium-haul journey. This distance typically involves several hours of flight time, often with layovers, making it a substantial trip for travelers.

How much is a round trip from Quito to Panama City

Regular price: $356 - $445

Prices for flights from Quito to Panama are currently below the regular range.

The regular price range for flights from Quito to Panama is between $356 and $445. The current lowest deal is $323 via Kayak for travel from Jul 25-Jul 28.

now $323

Low $356

High $445

The cheapest time to fly from Quito to Panama City

The cheapest month to fly from UIO to ECP is November, with a median price of $548. The most expensive month is April, with a median price of $1265. Prices are generally lower from January to December.

November

Cheapest

Flights from $548

April

Most Expensive

Flights from $1,265

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Quito to Panama City

Copa Airlines

Last-minute flights going from Quito to Panama City

Fri, Jul 17

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$434

$358

One-way

Fri, Jul 17

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

United Airlines

$572

$1,250

One-way

Sat, Jul 18

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$448

$358

One-way

Sat, Jul 18

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$420

$358

One-way

Sat, Jul 18

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$410

$358

One-way

Sat, Jul 18

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

United Airlines

$570

$1,250

One-way

Biggest price drops on these dates for flights from Quito to Panama City

2 nights

Jul 9 - Jul 11

$483 → $334

31%

3 nights

Jul 9 - Jul 12

$479 → $358

25%

4 nights

Jul 9 - Jul 13

$476 → $358

25%

5 nights

Jul 9 - Jul 14

$449 → $334

26%

Popular Airports to fly from Quito to Panama City

Quito - Panama City route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Quito to Panama City are below the typical level at $323.

📅 Best time to fly

November is historically cheapest

Historically, November is the cheapest month to fly from Quito to Panama City, with a median price of $548.

⏱️ Flight duration

Median flight time is 21h 47m

The median flight time from Quito to Panama City is 21 hours and 47 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant on this route, with a median of 3 stopovers.

🏆 Airline highlight

Copa Airlines offers direct flights

Copa Airlines offers direct flights from Quito to Panama City.

🎯 Booking tip

Deals appear regularly

Deals from Quito to Panama City appear regularly, about 0.47 deals per day.

Quito main airports to depart from

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International Airport is a good option for flights from Quito to Panama City.

📍 ~15 km from Quito (reachable by car)

💸 Flights from ~$345

Panama City main airports to arrive at

Northwest Florida Beaches International (ECP)

Cheapest

Northwest Florida Beaches International Airport is a convenient arrival airport for Panama City.

📍 ~20 km from city center (reachable by car)

💸 Flights from ~$896

Airports nearby Panama City used as alternative

Destin–Fort Walton Beach (VPS)

Destin–Fort Walton Beach is a useful alternative arrival airport with frequent flight options.

📍 ~100 km from Panama City (traffic on Highway 98 can significantly impact travel time).

💸 Flights from ~$606

Pensacola International (PNS)

Cheapest

Pensacola International is a reliable alternative arrival airport with superior connectivity and major carrier networks.

📍 ~120 km from Panama City (approximately 1.5 to 2 hours drive).

💸 Flights from ~$549

Tallahassee International (TLH)

Tallahassee International is a secondary option for arrivals, offering consistent regional jet service.

📍 ~140 km from Panama City (located in a different timezone).

💸 Flights from ~$632

Dothan Regional (DHN)

Dothan Regional is a niche alternative arrival airport with a simple terminal experience.

📍 ~110 km from Panama City (very limited flight schedule).

💸 Flights from ~$2190

Montgomery Regional (MGM)

Montgomery Regional provides additional carrier options for travelers heading north into Alabama.

📍 ~240 km from Panama City (significant driving distance).

💸 Flights from ~$1383

Business & First Class Flight Deals to Panama City

Discover luxury on the budget with premium cabin class on flights from Quito to Panama City.

Panama City, United States

66% AI deal score

$5,222

Frequently Asked Questions About Flights to Panama City

To find more affordable flights, consider being flexible with your travel dates and times. Using flight comparison sites can help you compare prices across various airlines and booking platforms. Sometimes, booking in advance or looking at flights during off-peak seasons may also help reduce costs.

Booking flights in advance, often several months before your intended departure, can sometimes lead to better prices. However, prices can fluctuate, so monitoring fares over time may help you identify a good booking window. Weekday bookings might also offer different pricing compared to weekends.

Comparing flights to and from nearby airports can sometimes reveal more economical travel options. While it may add to your ground transportation, the potential savings on airfare can be significant. Always factor in the total cost and travel time when considering alternative airports.

Related routes

Consider alternative routes from Quito

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Cheap Flights from Quito to Panama City

Today’s best flight deals from Quito to Panama City

Unlock all 500+ flight deals to Panama City and get alerts when great deals appear

Quito to Panama City: Overview

Insights for flights from Quito to Panama City

How much is a round trip from Quito to Panama City

The cheapest time to fly from Quito to Panama City

Direct flights from Quito to Panama City

Last-minute flights going from Quito to Panama City

Biggest price drops on these dates for flights from Quito to Panama City

Popular Airports to fly from Quito to Panama City

Quito - Panama City route insights

Recent fares are below the typical level

November is historically cheapest

Median flight time is 21h 47m

Connecting flights are dominant

Copa Airlines offers direct flights

Deals appear regularly

Quito main airports to depart from

Panama City main airports to arrive at

Airports nearby Panama City used as alternative

Business & First Class Flight Deals to Panama City

Best Elite deals to Panama City

Jul 02

Jul 07

Jul 02

Jul 07

Jul 02

Jul 07

Frequently Asked Questions About Flights to Panama City

How can I find cheap flights from Quito to Panama City?

When should I book flights from Quito to Panama City?

Should I compare nearby airports for flights from Quito to Panama City?

Are direct flights from Quito to Panama City always the best option?

Can flexible travel dates help on Quito to Panama City flights?

What extra costs should I check before booking Quito to Panama City flights?

Related routes

Consider alternative routes from Quito