Are direct flights from Des Moines to Syracuse always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, they are not always the most economical choice. Flights with one or more stops can often be cheaper, depending on the route and airline.

Can flexible travel dates help on Des Moines to Syracuse flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying on weekdays or during off-peak seasons often results in lower fares. Adjusting your departure or return by even a few days may lead to considerable savings.

What extra costs should I check before booking Des Moines to Syracuse flights?

Before booking, always review potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines, especially budget carriers, may charge for amenities that are included with other airlines. Also, consider ground transportation to and from the airports.

Flights From Des Moines

To Syracuse

Cheap Flights from Des Moines to Syracuse

Browse current best options from Des Moines. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Des Moines

RatePunk searches hundreds of travel sites at once for deals on flights to Syracuse

Prices updated 7 days ago

482 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)

Today’s best flight deals from Des Moines to Syracuse

Explore current cheapest deals departing from Des Moines to Syracuse

2027-01-06 – 2027-01-20
DSM - Syracuse
66% AI deal score
$332
$292
Round trip
2027-01-06 – 2027-01-22
DSM - Syracuse
48% AI deal score
$328
$313
Round trip
2027-01-24 – 2027-02-17
DSM - Syracuse
46% AI deal score
$330
$325
Round trip
2026-12-07 – 2026-12-14
DSM - Syracuse
74% AI deal score
$439
$338
Round trip
2027-01-06 – 2027-01-08
DSM - Syracuse
50% AI deal score
$368
$339
Round trip
2027-01-31 – 2027-02-17
DSM - Syracuse
46% AI deal score
$338
$340
Round trip
2026-12-07 – 2026-12-09
DSM - Syracuse
75% AI deal score
$464
$345
Round trip
2026-12-11 – 2026-12-18
DSM - Syracuse
77% AI deal score
$439
$347
Round trip
2026-11-09 – 2026-12-07
DSM - Syracuse
66% AI deal score
$380
$347
Round trip
2026-11-23 – 2026-12-07
DSM - Syracuse
66% AI deal score
$378
$348
Round trip

Des Moines to Syracuse: Overview

Insights for flights from Des Moines to Syracuse

The journey from Des Moines to Syracuse covers a distance of 1451 kilometers, classifying it as a short-haul route. This distance means you will typically find itineraries that involve connections rather than direct flights.

For those seeking cheap flights from Des Moines to Syracuse, fares right now are below the typical level. Recent fares for this route are typically $459–$459, with a median of $459.

When is the cheapest time to fly from Des Moines to Syracuse? Looking at recent data, August stands out as the most affordable month, with a median fare of $459.

Most itineraries for this route involve connections, as 0% of recent fares were non-stop. When flights do connect, the typical number of stopovers is 2.

A typical journey from Des Moines to Syracuse, including connections, takes approximately 8h 22m. This duration accounts for the time spent in the air and any layovers between flights.

How much is a round trip from Des Moines to Syracuse

Regular price: $289 - $552

Prices for flights from Des Moines to Syracuse are currently within the regular range.

Regular prices for this route are typically between $289 and $552. The current lowest deal is $302 with Allegiant Air, for travel from Jan 6-Jan 20.

now $302

Low $289

High $552

The cheapest time to fly from Des Moines to Syracuse

The cheapest month to fly from Des Moines to Syracuse is January, with a median price of $388. The most expensive month is October, with a median price of $539. Prices are generally lower from January to December.

January

Cheapest

Flights from $388

October

Most Expensive

Flights from $539

Jan

Feb

Oct

Nov

Dec

Direct flights from Des Moines to Syracuse

Allegiant Air

JetBlue Airways

United Airlines

Breeze Airways

Last-minute flights going from Des Moines to Syracuse

Thu, Nov 5

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$395

$603

One-way

Thu, Nov 5

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$393

$677

One-way

Thu, Nov 5

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$404

$687

One-way

Sun, Nov 8

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$394

$656

One-way

Sun, Nov 8

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$385

$730

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air, JetBlue Airways

$380

$347

One-way

Biggest price drops on these dates for flights from Des Moines to Syracuse

1 night

Dec 13 - Dec 14

$464 → $354

24%

7 nights

Dec 7 - Dec 14

$439 → $338

23%

1 night

Dec 6 - Dec 7

$464 → $372

20%

7 nights

Dec 11 - Dec 18

$439 → $348

21%

Popular Airports to fly from Des Moines to Syracuse

Des Moines - Syracuse route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Des Moines to Syracuse are below the typical level at $302.

📅 Best time to fly

August is historically cheapest

Historically, August is the cheapest month to fly from Des Moines to Syracuse, with a median price of $459.

⏱️ Flight duration

Connecting flights average 8h 22m

Connecting flights from Des Moines to Syracuse typically take 8h 22m.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant on this route, with a median of 2 stopovers.

🏆 Airline highlight

Allegiant Air offers deals

Allegiant Air has offered 44 deals for flights on this route recently.

🎯 Booking tip

Deals are rare

Deals on flights from Des Moines to Syracuse are rare, based on the last 30 days.

Des Moines main airports to depart from

Des Moines International (DSM)

Cheapest

Des Moines International Airport is a convenient departure point for flights to Syracuse.

📍 ~8 km from city center (reachable by car)

💸 Flights from ~$327

Syracuse main airports to arrive at

Syracuse Hancock International (SYR)

Cheapest

Fly into Syracuse Hancock International for direct access to Syracuse and surrounding areas.

📍 ~8 km from city center (reachable by car)

💸 Flights from ~$342

Airports nearby Syracuse used as alternative

Greater Rochester International (ROC)

Greater Rochester International (ROC) can be a useful alternative due to its proximity and comparable flight frequency.

📍 ~135 km from Syracuse (reachable by car, but account for Thruway tolls and potential lake-effect snow in winter).

💸 Flights from ~$326

Business & First Class Flight Deals to Syracuse

Discover luxury on the budget with premium cabin class on flights from Des Moines to Syracuse.

Elite

Best Elite deals to Syracuse

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From DSM

Elite

Nov 12

Syracuse, United States

76% AI deal score

$1,421

$1,003

Save $418

United Airlines

Business Class

Frequently Asked Questions About Flights to Syracuse

To find more affordable flights, consider being flexible with your travel dates and times. Using flight comparison websites can help you compare options from various providers. Looking into different airlines, including budget carriers, may also reveal lower prices.

Booking flights in advance often leads to better prices, especially for popular routes. However, prices can fluctuate, so monitoring fares over time may be beneficial. Last-minute deals can sometimes appear, but they are not guaranteed.

Comparing nearby airports at both your origin and destination can sometimes uncover more affordable flight options. While it may add to travel time, the potential savings could be significant. Always factor in ground transportation costs and convenience when considering this approach.

Related routes

More routes from Des Moines

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Flights to Syracuse from other cities

Flights from Amsterdam to Syracuse Flights from Atlanta to Syracuse Flights from Boston to Syracuse Flights from Dubai to Syracuse Flights from Phoenix to Syracuse Flights from Saskatoon to Syracuse

Des Moines to Syracuse: Overview

Insights for flights from Des Moines to Syracuse

For those seeking cheap flights from Des Moines to Syracuse, fares right now are below the typical level. Recent fares for this route are typically $459–$459, with a median of $459.

When is the cheapest time to fly from Des Moines to Syracuse? Looking at recent data, August stands out as the most affordable month, with a median fare of $459.

Most itineraries for this route involve connections, as 0% of recent fares were non-stop. When flights do connect, the typical number of stopovers is 2.

A typical journey from Des Moines to Syracuse, including connections, takes approximately 8h 22m. This duration accounts for the time spent in the air and any layovers between flights.

How much is a round trip from Des Moines to Syracuse

Regular price: $289 - $552

Prices for flights from Des Moines to Syracuse are currently within the regular range.

Regular prices for this route are typically between $289 and $552. The current lowest deal is $302 with Allegiant Air, for travel from Jan 6-Jan 20.

now $302

Low $289

High $552

The cheapest time to fly from Des Moines to Syracuse

January

Cheapest

Flights from $388

October

Most Expensive

Flights from $539

Jan

Feb

Oct

Nov

Dec

Direct flights from Des Moines to Syracuse

Allegiant Air

JetBlue Airways

United Airlines

Breeze Airways

Last-minute flights going from Des Moines to Syracuse

Thu, Nov 5

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$395

$603

One-way

Thu, Nov 5

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$393

$677

One-way

Thu, Nov 5

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$404

$687

One-way

Sun, Nov 8

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$394

$656

One-way

Sun, Nov 8

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air

$385

$730

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Syracuse

Des Moines (DSM) - Syracuse (SYR)

Allegiant Air, JetBlue Airways

$380

$347

One-way

Biggest price drops on these dates for flights from Des Moines to Syracuse

1 night

Dec 13 - Dec 14

$464 → $354

24%

7 nights

Dec 7 - Dec 14

$439 → $338

23%

1 night

Dec 6 - Dec 7

$464 → $372

20%

7 nights

Dec 11 - Dec 18

$439 → $348

21%

Popular Airports to fly from Des Moines to Syracuse