Are direct flights from Santo Domingo to Cartagena always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, connecting flights can sometimes be more affordable, depending on the route and demand. Evaluate whether the time savings of a direct flight outweigh potential cost differences.

Can flexible travel dates help on Santo Domingo to Cartagena flights?

Yes, being flexible with your travel dates can often lead to finding cheaper flights. Prices can vary significantly between different days of the week or even specific weeks. Flying during off-peak times or seasons usually offers more budget-friendly options.

What extra costs should I check before booking Santo Domingo to Cartagena flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Understanding these fees beforehand can help you budget accurately for your trip.

Flights From Santo Domingo

To Cartagena

Cheap Flights from Santo Domingo to Cartagena

Browse current best options from Santo Domingo. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Santo Domingo

RatePunk searches hundreds of travel sites at once for deals on flights to Cartagena

Prices updated 4 days ago

476 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 12, 2026.)

Today’s best flight deals from Santo Domingo to Cartagena

Explore current cheapest deals departing from Santo Domingo to Cartagena

2026-10-17 – 2026-10-27
SDQ - Cartagena
46% AI deal score
$297
$308
Round trip
2026-10-24 – 2026-10-31
SDQ - Cartagena
46% AI deal score
$298
$308
Round trip
2026-11-08 – 2026-11-24
SDQ - Cartagena
44% AI deal score
$258
$308
Round trip
2026-11-11 – 2026-11-15
SDQ - Cartagena
45% AI deal score
$301
$314
Round trip
2026-10-23 – 2026-11-06
SDQ - Cartagena
43% AI deal score
$267
$314
Round trip
2026-11-11 – 2026-11-16
SDQ - Cartagena
45% AI deal score
$299
$317
Round trip
2026-11-05 – 2026-11-08
SDQ - Cartagena
44% AI deal score
$303
$327
Round trip
2026-11-23 – 2026-12-12
SDQ - Cartagena
42% AI deal score
$255
$328
Round trip
2026-11-21 – 2026-12-09
SDQ - Cartagena
42% AI deal score
$256
$328
Round trip
2026-10-28 – 2026-11-04
SDQ - Cartagena
43% AI deal score
$297
$342
Round trip

Santo Domingo to Cartagena: Overview

Insights for flights from Santo Domingo to Cartagena

Fares for flights from Santo Domingo to Cartagena typically range from $533–$907, with a median price of $703. Right now, prices are near the typical level for this route.

When planning cheap flights from Santo Domingo to Cartagena, consider that the cheapest month to fly is often January, with a median fare of $436. Other affordable times include July, where the median fare is $515, and December, with a median of $633.

A typical journey from Santo Domingo to Cartagena takes about 2h 2m. However, since most itineraries connect at least once, the median connecting flight time is significantly longer at 13h 20m, compared to the 2h 2m for non-stop flights.

This route covers a distance of 1088 kilometers, classifying it as a short-haul journey. Most itineraries on this route connect at least once, with only 8.2% of recent fares being non-stop. For connecting flights, the typical number of stopovers is 2.

How much is a round trip from Santo Domingo to Cartagena

Regular price: $281 - $364

Prices for flights from Santo Domingo to Cartagena are currently within the regular range.

The regular price range for flights from Santo Domingo to Cartagena is between $281 and $364. The current lowest deal is $308 with Copa Airlines for travel from Oct 23-Oct 26.

now $308

Low $281

High $364

The cheapest time to fly from Santo Domingo to Cartagena

The cheapest month to fly from Santo Domingo to Cartagena is January, with a median price of $310. The most expensive month is August, with a median price of $788. Generally, prices are lower from January to December.

January

Cheapest

Flights from $310

August

Most Expensive

Flights from $788

Jan

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Santo Domingo to Cartagena

Last-minute flights going from Santo Domingo to Cartagena

Fri, Oct 9

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$358

$416

One-way

Sun, Oct 11

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Maersk Air

$215

$419

One-way

Mon, Oct 12

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$321

$515

One-way

Wed, Oct 14

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$392

$416

One-way

Wed, Oct 14

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$315

$428

One-way

Fri, Oct 16

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Maersk Air

$204

$410

One-way

Biggest price drops on these dates for flights from Santo Domingo to Cartagena

3 nights

Oct 23 - Oct 26

$322 → $308

2 nights

Oct 23 - Oct 25

$322 → $312

2 nights

Oct 30 - Nov 1

$312 → $312

5 nights

Nov 8 - Nov 13

$300 → $308

Popular Airports to fly from Santo Domingo to Cartagena

Santo Domingo - Cartagena route insights

💸 Price insights

Recent fares near the typical level

Recent fares from Santo Domingo to Cartagena are near the typical level of $703.

📅 Best time to fly

January offers the lowest median prices

Historically, January has the lowest median price at $436, followed by July at $515.

⏱️ Flight duration

Direct flights take 2h 2m

The typical direct flight from Santo Domingo to Cartagena takes 2 hours and 2 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Only 8.2% of recent fares are direct, with connecting flights typically having 2 stopovers.

🏆 Airline highlight

Copa Airlines offers a deal at $308

A recent deal on Copa Airlines for $308 is available for October 23-26.

🎯 Booking tip

Deals appear regularly

Deals on this route appear regularly, with a median price of $334 in recent offers.

Santo Domingo main airports to depart from

Las Américas International (SDQ)

Cheapest

Fly from Las Américas International for a convenient departure to Cartagena.

📍 ~28 km from Santo Domingo city center (reachable by car)

💸 Flights from ~$252

La Isabela International (JBQ)

Consider La Isabela International for an alternative departure option to Cartagena.

📍 ~11 km from Santo Domingo city center (reachable by car)

💸 Flights from ~$878

Cartagena main airports to arrive at

Rafael Núñez International (CTG)

Cheapest

Rafael Núñez International Airport is the primary airport for flights arriving in Cartagena.

📍 ~7 km from city center (reachable by car)

💸 Flights from ~$252

Airports nearby Cartagena used as alternative

Ernesto Cortissoz International (BAQ)

Ernesto Cortissoz International is a practical alternative due to its proximity and status as a major hub.

📍 ~95 km from Cartagena (reachable by car, approx. 1.5 to 2 hours drive).

💸 Flights from ~$396

Business & First Class Flight Deals to Cartagena

Discover luxury on the budget with premium cabin class on flights from Santo Domingo to Cartagena.

Elite

Best Elite deals to Cartagena

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From SDQ

Elite

Oct 28

Cartagena, Colombia

69% AI deal score

$1,144

$862

Save $282

Copa Airlines

Business Class

From SDQ

Elite

Oct 17

Cartagena, Colombia

69% AI deal score

$1,176

$888

Save $288

Copa Airlines

Business Class

From SDQ

Elite

Dec 05

Cartagena, Colombia

68% AI deal score

$1,050

$844

Save $206

Copa Airlines

Business Class

From SDQ

Elite

Dec 22

Cartagena, Colombia

68% AI deal score

$1,093

$862

Save $231

Copa Airlines

Business Class

From SDQ

Elite

Dec 19

Cartagena, Colombia

68% AI deal score

$1,091

$868

Save $223

Copa Airlines

Business Class

From SDQ

Elite

Oct 17

Cartagena, Colombia

66% AI deal score

$1,348

$1,109

Save $239

Copa Airlines

Business Class

From SDQ

Elite

Dec 05

Cartagena, Colombia

49% AI deal score

$1,166

$1,082

Save $84

Copa Airlines

Business Class

From SDQ

Elite

Oct 17

Cartagena, Colombia

49% AI deal score

$1,217

$1,109

Save $108

Copa Airlines

Business Class

From SDQ

Elite

Oct 28

Cartagena, Colombia

48% AI deal score

$1,117

$1,082

Save $35

Copa Airlines

Business Class

From SDQ

Elite

Oct 17

Cartagena, Colombia

48% AI deal score

$1,165

$1,109

Save $56

Copa Airlines

Business Class

From SDQ

Elite

Oct 17

Cartagena, Colombia

48% AI deal score

$1,168

$1,109

Save $59

Copa Airlines

Business Class

From SDQ

Elite

Oct 17

Cartagena, Colombia

48% AI deal score

$1,194

$1,164

Save $30

Copa Airlines

Business Class

Frequently Asked Questions About Flights to Cartagena

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you discover better deals. Setting up price alerts may notify you when fares drop for your desired route.

Booking in advance often provides more options and potentially lower prices, especially for popular routes. However, last-minute deals can sometimes appear, so it's wise to monitor fares. There isn't a single best time, as prices can fluctuate.

Comparing nearby airports can sometimes reveal more economical flight options or different schedules. While it may add to your ground travel time, the potential savings could be significant. Always factor in the cost and convenience of transportation to and from alternative airports.

Related routes

More routes from Santo Domingo

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Flights to Cartagena from other cities

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Santo Domingo to Cartagena: Overview

Insights for flights from Santo Domingo to Cartagena

Fares for flights from Santo Domingo to Cartagena typically range from $533–$907, with a median price of $703. Right now, prices are near the typical level for this route.

How much is a round trip from Santo Domingo to Cartagena

Regular price: $281 - $364

Prices for flights from Santo Domingo to Cartagena are currently within the regular range.

The regular price range for flights from Santo Domingo to Cartagena is between $281 and $364. The current lowest deal is $308 with Copa Airlines for travel from Oct 23-Oct 26.

now $308

Low $281

High $364

The cheapest time to fly from Santo Domingo to Cartagena

January

Cheapest

Flights from $310

August

Most Expensive

Flights from $788

Jan

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Santo Domingo to Cartagena

Last-minute flights going from Santo Domingo to Cartagena

Fri, Oct 9

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$358

$416

One-way

Sun, Oct 11

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Maersk Air

$215

$419

One-way

Mon, Oct 12

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$321

$515

One-way

Wed, Oct 14

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$392

$416

One-way

Wed, Oct 14

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Avianca

$315

$428

One-way

Fri, Oct 16

⌛ Last-Minute

SDQ - Cartagena

Santo Domingo (SDQ) - Cartagena (CTG)

Maersk Air

$204

$410

One-way

Biggest price drops on these dates for flights from Santo Domingo to Cartagena

3 nights

Oct 23 - Oct 26

$322 → $308

2 nights

Oct 23 - Oct 25

$322 → $312

2 nights

Oct 30 - Nov 1

$312 → $312

5 nights

Nov 8 - Nov 13

$300 → $308

Popular Airports to fly from Santo Domingo to Cartagena

Santo Domingo - Cartagena route insights

💸 Price insights

Recent fares near the typical level

Recent fares from Santo Domingo to Cartagena are near the typical level of $703.

📅 Best time to fly

January offers the lowest median prices

Historically, January has the lowest median price at $436, followed by July at $515.

⏱️ Flight duration

Direct flights take 2h 2m

The typical direct flight from Santo Domingo to Cartagena takes 2 hours and 2 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Only 8.2% of recent fares are direct, with connecting flights typically having 2 stopovers.

🏆 Airline highlight

Copa Airlines offers a deal at $308

A recent deal on Copa Airlines for $308 is available for October 23-26.

🎯 Booking tip

Deals appear regularly

Deals on this route appear regularly, with a median price of $334 in recent offers.

Santo Domingo main airports to depart from

Las Américas International (SDQ)

Cheapest

Fly from Las Américas International for a convenient departure to Cartagena.

📍 ~28 km from Santo Domingo city center (reachable by car)

💸 Flights from ~$252

La Isabela International (JBQ)

Consider La Isabela International for an alternative departure option to Cartagena.

📍 ~11 km from Santo Domingo city center (reachable by car)

💸 Flights from ~$878

Cartagena main airports to arrive at

Rafael Núñez International (CTG)

Cheapest

Rafael Núñez International Airport is the primary airport for flights arriving in Cartagena.

📍 ~7 km from city center (reachable by car)

💸 Flights from ~$252

Airports nearby Cartagena used as alternative

Ernesto Cortissoz International (BAQ)

Ernesto Cortissoz International is a practical alternative due to its proximity and status as a major hub.

Cartagena, Colombia

48% AI deal score

$1,194

$1,164

Save $30

Copa Airlines

Business Class

Frequently Asked Questions About Flights to Cartagena

Cheap Flights from Santo Domingo to Cartagena

Today’s best flight deals from Santo Domingo to Cartagena

Santo Domingo to Cartagena: Overview

Insights for flights from Santo Domingo to Cartagena

How much is a round trip from Santo Domingo to Cartagena

The cheapest time to fly from Santo Domingo to Cartagena

Direct flights from Santo Domingo to Cartagena

Last-minute flights going from Santo Domingo to Cartagena

Biggest price drops on these dates for flights from Santo Domingo to Cartagena

Popular Airports to fly from Santo Domingo to Cartagena

Santo Domingo - Cartagena route insights

Recent fares near the typical level

January offers the lowest median prices

Direct flights take 2h 2m

Connecting flights are dominant

Copa Airlines offers a deal at $308

Deals appear regularly

Santo Domingo main airports to depart from

Cartagena main airports to arrive at

Airports nearby Cartagena used as alternative

Business & First Class Flight Deals to Cartagena

Best Elite deals to Cartagena

Oct 28

Oct 17

Dec 05

Dec 22

Dec 19

Oct 17

Dec 05

Oct 17

Oct 28

Oct 17

Oct 17

Oct 17

Frequently Asked Questions About Flights to Cartagena

How can I find cheap flights from Santo Domingo to Cartagena?

When should I book flights from Santo Domingo to Cartagena?

Should I compare nearby airports for flights from Santo Domingo to Cartagena?

Are direct flights from Santo Domingo to Cartagena always the best option?

Can flexible travel dates help on Santo Domingo to Cartagena flights?

What extra costs should I check before booking Santo Domingo to Cartagena flights?

Related routes

More routes from Santo Domingo

Flights to Cartagena from other cities

Santo Domingo to Cartagena: Overview

Insights for flights from Santo Domingo to Cartagena

How much is a round trip from Santo Domingo to Cartagena

The cheapest time to fly from Santo Domingo to Cartagena

Direct flights from Santo Domingo to Cartagena

Last-minute flights going from Santo Domingo to Cartagena

Biggest price drops on these dates for flights from Santo Domingo to Cartagena

Popular Airports to fly from Santo Domingo to Cartagena

Santo Domingo - Cartagena route insights

Recent fares near the typical level

January offers the lowest median prices

Direct flights take 2h 2m

Connecting flights are dominant

Copa Airlines offers a deal at $308

Deals appear regularly

Santo Domingo main airports to depart from

Cartagena main airports to arrive at

Airports nearby Cartagena used as alternative

Business & First Class Flight Deals to Cartagena

Best Elite deals to Cartagena

Oct 28

Oct 17

Dec 05

Dec 22

Dec 19

Oct 17

Dec 05

Oct 17

Oct 28

Oct 17

Oct 17

Oct 17

Frequently Asked Questions About Flights to Cartagena

How can I find cheap flights from Santo Domingo to Cartagena?

When should I book flights from Santo Domingo to Cartagena?

Should I compare nearby airports for flights from Santo Domingo to Cartagena?