Are direct flights from Knoxville to Florence always the best option?

Direct flights can offer convenience and save travel time, but they are not always the cheapest option. Flights with layovers may sometimes be more affordable, especially for longer distances. Consider your budget and time constraints when deciding between direct and connecting flights.

Can flexible travel dates help on Knoxville to Florence flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Mid-week travel or flying during off-peak seasons often results in lower fares compared to weekends or major holidays. Adjusting your departure or return by a few days may unlock better deals.

What extra costs should I check before booking Knoxville to Florence flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Knoxville

To Florence

Cheap Flights from Knoxville to Florence

Browse current best options from Knoxville. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Knoxville

RatePunk searches hundreds of travel sites at once for deals on flights to Florence

Prices updated 4 days ago

476 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 12, 2026.)

Today’s best flight deals from Knoxville to Florence

Explore current cheapest deals departing from Knoxville to Florence

2027-03-07 – 2027-03-18
TYS - Florence
81% AI deal score
$830
$743
Round trip
2027-02-16 – 2027-02-23
TYS - Florence
81% AI deal score
$841
$751
Round trip
2027-02-09 – 2027-02-16
TYS - Florence
80% AI deal score
$830
$751
Round trip
2027-01-26 – 2027-02-02
TYS - Florence
83% AI deal score
$889
$751
Round trip
2027-01-20 – 2027-01-27
TYS - Florence
82% AI deal score
$868
$751
Round trip
2027-03-16 – 2027-03-23
TYS - Florence
80% AI deal score
$829
$752
Round trip
2026-11-08 – 2026-11-24
TYS - Florence
77% AI deal score
$806
$823
Round trip
2026-12-02 – 2026-12-09
TYS - Florence
80% AI deal score
$927
$832
Round trip
2026-12-09 – 2026-12-16
TYS - Florence
80% AI deal score
$938
$843
Round trip
2026-11-25 – 2026-12-02
TYS - Florence
77% AI deal score
$850
$865
Round trip

Knoxville to Florence: Overview

Insights for flights from Knoxville to Florence

Fares for flights from Knoxville to Florence typically range from $1024–$1860, with a median of $1289. Right now, fares are below the typical level, and only 7% of recent fares were classified as a good price. Deals are infrequent, so a price alert helps secure cheap flights from Knoxville to Florence.

When considering the cheapest time to fly from Knoxville to Florence, November stands out with a median fare of $1081. Following closely, February offers a median fare of $1193, and December presents a median of $1222, making these months generally more affordable for this route.

A typical journey from Knoxville to Florence takes about 37h 43m, including connections. This is a long-haul route, covering a substantial distance of 7716 km.

For flights from Knoxville to Florence, most itineraries connect at least once, as 0% of recent fares were non-stop. This means you should expect at least one stop on your trip.

How much is a round trip from Knoxville to Florence

Regular price: $700 - $1,311

Prices from Knoxville to Florence are currently within the regular range.

The regular price range for flights from Knoxville to Florence is $700 to $1311. The current lowest deal is $737 with United Airlines for travel from Mar 9-Mar 18.

now $737

Low $700

High $1,311

The cheapest time to fly from Knoxville to Florence

The cheapest month to fly from TYS to FLR is November, with a median price of $1081. The most expensive month to fly is May, with a median price of $2056. Prices are generally lower from February to December.

November

Cheapest

Flights from $1,081

May

Most Expensive

Flights from $2,056

Feb

May

Oct

Nov

Dec

Direct flights from Knoxville to Florence

United Airlines

Vueling Airlines

Allegiant Air

Air Canada

Last-minute flights going from Knoxville to Florence

Thu, Oct 15

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$1,151

$1,196

One-way

Fri, Oct 16

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$1,014

$1,140

One-way

Wed, Oct 21

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$926

$1,062

One-way

Thu, Oct 22

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

Deutsche Luft Hansa

$943

$1,312

One-way

Sat, Oct 24

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$902

$3,092

One-way

Mon, Oct 26

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$906

$984

One-way

Biggest price drops on these dates for flights from Knoxville to Florence

7 nights

Jan 26 - Feb 2

$871 → $751

14%

7 nights

Jan 20 - Jan 27

$856 → $745

13%

7 nights

Mar 23 - Mar 30

$854 → $754

12%

7 nights

Dec 2 - Dec 9

$919 → $822

11%

Popular Airports to fly from Knoxville to Florence

Knoxville - Florence route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Knoxville to Florence are below the typical level.

📅 Best time to fly

November is historically cheapest

Historically, November is the cheapest month to fly from Knoxville to Florence, with a median price of $1081.

⏱️ Flight duration

Flights average 37h 43m

Flights from Knoxville to Florence typically take 37h 43m, covering a distance of 7716 km.

✈️ Airlines & availability

Connecting flights are dominant

Direct flights are not available on this route; connecting flights are dominant.

🏆 Airline highlight

United Airlines has deals

United Airlines has 24 deals for connecting flights from Knoxville to Florence.

🎯 Booking tip

Deals are rare on this route

Deals from Knoxville to Florence are rare, appearing less frequently than other routes.

Knoxville main airports to depart from

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport is a convenient departure point for flights from Knoxville to Florence.

📍 ~18 km from city center (reachable by car)

💸 Flights from ~$745

Florence main airports to arrive at

Florence (FLR)

Cheapest

Fly into Florence Airport for convenient access to the historic city center of Florence.

📍 ~6 km from city center (reachable by car)

💸 Flights from ~$743

Airports nearby Florence used as alternative

Pisa International (PSA)

Pisa International is a major hub for low-cost carriers and offers frequent shuttle bus and train connections.

📍 ~65 km from Florence (reachable by shuttle bus and train)

💸 Flights from ~$851

Business & First Class Flight Deals to Florence

$8,847

Save $332

United Airlines, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

Frequently Asked Questions About Flights to Florence

To find cheaper flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you identify more affordable options. Setting up price alerts may notify you when fares drop for your desired route.

Booking flights in advance, often several months before your trip, can sometimes result in lower prices. However, prices can fluctuate, so monitoring fares over time may help you find a good deal. Last-minute bookings usually carry a higher cost.

Comparing nearby airports at both your origin and destination can often uncover more flight options or potentially lower fares. Sometimes, flying into or out of a slightly more distant airport may offer significant savings. Remember to factor in the cost and time of ground transportation.

Related routes

More routes from Knoxville

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Flights to Florence from other cities

Flights from Athens to Florence Flights from Atlanta to Florence Flights from Austin to Florence Flights from Barcelona to Florence Flights from Bologna to Florence Flights from Kelowna to Florence Flights from Málaga to Florence Flights from Toronto to Florence Flights from Vienna to Florence Flights from Vigo to Florence Flights from Warsaw to Florence Flights from Zürich to Florence

Knoxville to Florence: Overview

Insights for flights from Knoxville to Florence

A typical journey from Knoxville to Florence takes about 37h 43m, including connections. This is a long-haul route, covering a substantial distance of 7716 km.

For flights from Knoxville to Florence, most itineraries connect at least once, as 0% of recent fares were non-stop. This means you should expect at least one stop on your trip.

How much is a round trip from Knoxville to Florence

Regular price: $700 - $1,311

Prices from Knoxville to Florence are currently within the regular range.

The regular price range for flights from Knoxville to Florence is $700 to $1311. The current lowest deal is $737 with United Airlines for travel from Mar 9-Mar 18.

now $737

Low $700

High $1,311

The cheapest time to fly from Knoxville to Florence

November

Cheapest

Flights from $1,081

May

Most Expensive

Flights from $2,056

Feb

May

Oct

Nov

Dec

Direct flights from Knoxville to Florence

United Airlines

Vueling Airlines

Allegiant Air

Air Canada

Last-minute flights going from Knoxville to Florence

Thu, Oct 15

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$1,151

$1,196

One-way

Fri, Oct 16

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$1,014

$1,140

One-way

Wed, Oct 21

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$926

$1,062

One-way

Thu, Oct 22

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

Deutsche Luft Hansa

$943

$1,312

One-way

Sat, Oct 24

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$902

$3,092

One-way

Mon, Oct 26

⌛ Last-Minute

TYS - Florence

Knoxville (TYS) - Florence (FLR)

United Airlines

$906

$984

One-way

Biggest price drops on these dates for flights from Knoxville to Florence

7 nights

Jan 26 - Feb 2

$871 → $751

14%

7 nights

Jan 20 - Jan 27

$856 → $745

13%

7 nights

Mar 23 - Mar 30

$854 → $754

12%

7 nights

Dec 2 - Dec 9

$919 → $822

11%

Popular Airports to fly from Knoxville to Florence

Knoxville - Florence route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Knoxville to Florence are below the typical level.

📅 Best time to fly

November is historically cheapest

Historically, November is the cheapest month to fly from Knoxville to Florence, with a median price of $1081.

⏱️ Flight duration

Flights average 37h 43m

Flights from Knoxville to Florence typically take 37h 43m, covering a distance of 7716 km.

✈️ Airlines & availability

Connecting flights are dominant

Direct flights are not available on this route; connecting flights are dominant.

🏆 Airline highlight

United Airlines has deals

United Airlines has 24 deals for connecting flights from Knoxville to Florence.

🎯 Booking tip

Deals are rare on this route

Deals from Knoxville to Florence are rare, appearing less frequently than other routes.

Knoxville main airports to depart from

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport is a convenient departure point for flights from Knoxville to Florence.

📍 ~18 km from city center (reachable by car)

💸 Flights from ~$745

Florence main airports to arrive at

Florence (FLR)

Cheapest

Fly into Florence Airport for convenient access to the historic city center of Florence.

📍 ~6 km from city center (reachable by car)

💸 Flights from ~$743

Airports nearby Florence used as alternative

Pisa International (PSA)

Pisa International is a major hub for low-cost carriers and offers frequent shuttle bus and train connections.

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

From TYS

Elite

Dec 30

Florence, Italy

76% AI deal score

$10,481

Aer Lingus, +1

Business Class

Frequently Asked Questions About Flights to Florence

Cheap Flights from Knoxville to Florence

Today’s best flight deals from Knoxville to Florence

Knoxville to Florence: Overview

Insights for flights from Knoxville to Florence

How much is a round trip from Knoxville to Florence

The cheapest time to fly from Knoxville to Florence

Direct flights from Knoxville to Florence

Last-minute flights going from Knoxville to Florence

Biggest price drops on these dates for flights from Knoxville to Florence

Popular Airports to fly from Knoxville to Florence

Knoxville - Florence route insights

Recent fares are below the typical level

November is historically cheapest

Flights average 37h 43m

Connecting flights are dominant

United Airlines has deals

Deals are rare on this route

Knoxville main airports to depart from

Florence main airports to arrive at

Airports nearby Florence used as alternative

Business & First Class Flight Deals to Florence

Best Elite deals to Florence

Nov 08

Nov 08

Nov 23

Oct 22

Nov 02

Dec 30

Dec 30

Dec 30

Dec 30

Dec 30

Dec 30

Dec 30

Frequently Asked Questions About Flights to Florence

How can I find cheap flights from Knoxville to Florence?

When should I book flights from Knoxville to Florence?

Should I compare nearby airports for flights from Knoxville to Florence?

Are direct flights from Knoxville to Florence always the best option?

Can flexible travel dates help on Knoxville to Florence flights?

What extra costs should I check before booking Knoxville to Florence flights?

Related routes

More routes from Knoxville

Flights to Florence from other cities

Knoxville to Florence: Overview

Insights for flights from Knoxville to Florence

How much is a round trip from Knoxville to Florence

The cheapest time to fly from Knoxville to Florence

Direct flights from Knoxville to Florence

Last-minute flights going from Knoxville to Florence

Biggest price drops on these dates for flights from Knoxville to Florence

Popular Airports to fly from Knoxville to Florence

Knoxville - Florence route insights

Recent fares are below the typical level

November is historically cheapest

Flights average 37h 43m

Connecting flights are dominant

United Airlines has deals

Deals are rare on this route

Knoxville main airports to depart from

Florence main airports to arrive at

Airports nearby Florence used as alternative

Business & First Class Flight Deals to Florence

Best Elite deals to Florence

Nov 08

Nov 08

Nov 23

Oct 22

Nov 02

Dec 30

Dec 30

Dec 30

Dec 30

Dec 30

Dec 30

Dec 30

Frequently Asked Questions About Flights to Florence

How can I find cheap flights from Knoxville to Florence?

When should I book flights from Knoxville to Florence?

Should I compare nearby airports for flights from Knoxville to Florence?