From Panama City
Cheap Flights from Panama City
Browse current best options from Panama City. Become a member to unlock all deals and get alerts when new deals appear.
Deals from
Panama City
RatePunk searches hundreds of travel sites at once for deals on flights from Panama City
Prices updated 24 days ago
486,190 searches this week
171 airlines compared
80%+ AI score for best value
Fares are subject to change and may not be available for all dates. (Data last updated May 29, 2026.)
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Today’s best flight deals from Panama City
Explore current cheapest deals departing from Panama City
One-way
Sort by: Cheapest
ECP
Houston
United States • Oct 2026
$125
$81
One-way
ECP
Austin
United States • Aug 2026
$100
$99
One-way
ECP
Houston
United States • Jul 2026
$122
$99
One-way
ECP
St. Louis
United States • Aug 2026
$209
$105
One-way
ECP
Kansas City
United States • Sep 2026
$210
$106
One-way
ECP
Indianapolis
United States • Sep 2026
$207
$119
One-way
ECP
Knoxville
United States • Oct 2026
$245
$119
One-way
ECP
Raleigh
United States • Dec 2026
$217
$126
One-way
ECP
Dallas
United States • Jul 2026
$165
$128
One-way
ECP
Nashville
United States • Aug 2026
$125
$128
One-way
Unlock all 500+ flight deals from Panama City and get alerts when great deals appear
Origin Intelligence — 715 Destinations from Panama City Tracked
Insights for flights from Panama City
Most popular airlines from Panama City
Deutsche Luft Hansa
Southwest Airlines
United Airlines
American Airlines
American Eagle Airlines
PSA Airlines
Midwest Airlines
SkyWest Airlines
Last-minute flights going from Panama City soon
Sat, Jun 20
ECP - Melbourne
Panama City (ECP) - Melbourne (MEL)
American Airlines
$1,630
$1,084
One-way
Mon, Jun 29
ECP - Prague
Panama City (ECP) - Prague (PRG)
United Airlines
$1,199
$991
One-way
Tue, Jun 30
ECP - Lynchburg
Panama City (ECP) - Lynchburg (LYH)
American Airlines
$867
$463
One-way
Wed, Jun 17
ECP - Killeen
Panama City (ECP) - Killeen (GRK)
American Airlines
$1,123
$529
One-way
Tue, Jun 16
ECP - Charlottesville
Panama City (ECP) - Charlottesville (CHO)
Deutsche Luft Hansa
$570
$414
One-way
Fri, Jun 19
ECP - Budapest
Panama City (ECP) - Budapest (BUD)
Air France
$1,349
$1,340
One-way
Most popular destinations to fly from Panama City
Okinawa Island
Japan • Sep 2026
from
$905
Tokyo
Japan • Nov 2026
from
$908
Nairobi
Kenya • Nov 2026
from
$1,158
Budapest
Hungary • Aug 2026
from
$806
Tokyo
Japan • Sep 2026
from
$893
Melbourne
Australia • Jun 2026
from
$1,084
Biggest price drops on international destinations from Panama City
ECP - Okinawa Island
$1,763 → $905
ECP - Melbourne
$1,630 → $1,084
ECP - Tokyo
$1,334 → $908
ECP - Tokyo
$1,310 → $893
Popular Airports from Panama City
Panama City airport insights
🎯 Booking tip
Watch fares to Houston
Flights to Houston are often available for as little as $81 one-way.
📅 Cheapest travel period
Jan, Sep
Flights from ECP tend to be cheaper in January and September.
⏱️ Best time to book
8+ months in advance
Booking 8+ months in advance from ECP is often cheaper than booking closer to departure.
✈️ Airlines to watch
Southwest Airlines, Deutsche Luft Hansa, United Airlines, American Airlines
Major US carriers and low-cost airlines offer diverse flight options from Panama City.
💸 Cheapest deals found
From ~$81 direct / ~$175 roundtrip
Ultra-low fares cluster on routes to cities in the United States, including Houston and Austin.
🗓️ Best days to catch a deal
Wed - Sat - Thu
The cheapest days to fly from ECP are Wednesday, Saturday, and Thursday, with fares from $99.
Panama City main airports to depart from
Northwest Florida Beaches International (ECP)
ECP is ideal for travelers seeking flights from the Panama City area, offering a range of destinations.
📍 ~25 km from city center (reachable by car)
💸 Flights from ~$175
Airports nearby Panama City used as alternative
Destin–Fort Walton Beach (VPS)
Destin–Fort Walton Beach is a useful alternative with frequent flight options and similar airline service.
📍 ~85 km from Panama City (reachable by car)
💸 Flights from ~$55
Pensacola International (PNS)
Pensacola International offers superior connectivity and a full range of cabin classes for major carrier networks.
📍 ~115 km from Panama City (reachable by car)
💸 Flights from ~$78
Tallahassee International (TLH)
Tallahassee International is a state capital airport with consistent regional jet service and reasonable driving distance.
📍 ~150 km from Panama City (reachable by car)
💸 Flights from ~$77
Dothan Regional (DHN)
Dothan Regional offers a relatively close geographic proximity and a simple terminal for quick departures.
📍 ~115 km from Panama City (reachable by car)
💸 Flights from ~$259
Montgomery Regional (MGM)
Montgomery Regional is an alternative hub for travelers heading north into Alabama with additional carrier options.
📍 ~240 km from Panama City (reachable by car)
💸 Flights from ~$221
Business & First Class Flight Deals from Panama City
Discover luxury on the budget with premium cabin class on flights from Panama City.
Elite
Best Elite deals from Panama City
Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.
From ECP
Elite
Seattle
United States • Oct 2026
86% AI deal score
$1,271
$909
Save $362
Delta
Business Class
From ECP
Elite
San Francisco
United States • Aug 2026
83% AI deal score
$1,181
$976
Save $205
Delta
Business Class
From ECP
Elite
Aruba
Aruba • Aug 2026
82% AI deal score
$1,609
$1,169
Save $440
American
Business Class
From ECP
Elite
Willemstad
Curaçao • Aug 2026
82% AI deal score
$1,760
$1,248
Save $512
American
Business Class
From ECP
Elite
Houston
United States • Jul 2026
81% AI deal score
$744
$577
Save $167
United Airlines
Business Class
From ECP
Elite
Chicago
United States • Aug 2026
79% AI deal score
$876
$716
Save $160
United Airlines
Business Class
From ECP
Elite
Honolulu
United States • Mar 2027
79% AI deal score
$5,106
$3,137
Save $1,969
United Airlines
Business Class
From ECP
Elite
Los Angeles
United States • Aug 2026
74% AI deal score
$1,057
$968
Save $89
Delta
Business Class
From ECP
Elite
San Diego
United States • Aug 2026
73% AI deal score
$1,037
$931
Save $106
Delta
Business Class
From ECP
Elite
Washington, D.C.
United States • Sep 2026
69% AI deal score
$594
$494
Save $100
American
Business Class
From ECP
Elite
New Orleans
United States • Aug 2026
69% AI deal score
$689
$574
Save $115
Delta
Business Class
From ECP
Elite
Chicago
United States • Aug 2026
67% AI deal score
$647
$583
Save $64
American
Business Class
From ECP
Elite
Nashville
United States • Aug 2026
66% AI deal score
$606
$517
Save $89
American
Business Class