Are there direct flights from Cartagena to Santiago de Chile?

Direct flights from Cartagena to Santiago de Chile are available, but they represent a small portion of the total. Historically, only about 10% of flights on this route have been direct. For flights with stopovers, travelers typically experience one stop. The majority of flights on this route involve at least one connection.

How long does it take to fly from Cartagena to Santiago de Chile?

The direct flight from Cartagena to Santiago de Chile typically takes approximately 5 hours and 30 minutes. This route covers a distance of about 4900 kilometers. For flights that include one stop, the median travel time increases significantly to about 10 hours and 20 minutes. Travelers should account for this difference when planning their journey.

Should I set a price alert for Cartagena to Santiago de Chile flights?

Historically, deals for flights from Cartagena to Santiago de Chile have been frequent. This suggests that setting a price alert could be beneficial for travelers looking to find lower fares. Given the historical frequency of price changes, an alert can help you track fluctuations and potentially secure a more favorable price for your trip.

Flights From Cartagena

To Santiago de Chile

Cheap Flights from Cartagena to Santiago de Chile

Browse current best options from Cartagena. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Cartagena

RatePunk searches hundreds of travel sites at once for deals on flights to Santiago de Chile

Prices updated today

456 airlines compared

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Fares are subject to change and may not be available for all dates. (Data last updated Aug 31, 2026.)

Today’s best flight deals from Cartagena to Santiago de Chile

Explore current cheapest deals departing from Cartagena to Santiago de Chile

2026-10-01 – 2026-10-22
CTG - Santiago de Chile
85% AI deal score
$350
$300
Round trip
2026-11-26 – 2026-11-30
CTG - Santiago de Chile
87% AI deal score
$391
$301
Round trip
2026-11-26 – 2026-11-29
CTG - Santiago de Chile
87% AI deal score
$391
$302
Round trip
2026-09-18 – 2026-09-24
CTG - Santiago de Chile
88% AI deal score
$412
$307
Round trip
2026-10-01 – 2026-10-15
CTG - Santiago de Chile
85% AI deal score
$363
$311
Round trip
2026-11-06 – 2026-11-09
CTG - Santiago de Chile
86% AI deal score
$390
$311
Round trip
2026-11-26 – 2026-11-28
CTG - Santiago de Chile
86% AI deal score
$391
$314
Round trip
2026-09-17 – 2026-09-24
CTG - Santiago de Chile
87% AI deal score
$412
$319
Round trip
2026-10-02 – 2026-10-22
CTG - Santiago de Chile
77% AI deal score
$347
$320
Round trip
2026-11-06 – 2026-11-23
CTG - Santiago de Chile
77% AI deal score
$344
$320
Round trip

Cartagena to Santiago de Chile: Overview

Insights for flights from Cartagena to Santiago de Chile

For cheap flights from Cartagena to Santiago de Chile, fares typically range from $369–$433, with a median of $394 over the last 90 days. Right now, current fares are near the typical level, and about 18% of recent fares were classified as a good price. New deals appear almost daily, suggesting frequent opportunities to find competitive pricing for this route.

When is the cheapest time to fly from Cartagena to Santiago de Chile? The most affordable times to travel are typically in December, with a median fare of $264. Other cost-effective months include November, where the median fare is $296, and August, with a median of $333. Planning your trip during these months could lead to significant savings.

A typical journey from Cartagena to Santiago de Chile takes about 12h 30m, including connections. Given that most itineraries connect at least once, this duration accounts for layovers. Only a very small share of recent fares, about 0.1%, were for non-stop flights, meaning most travelers should expect to make at least one stopover.

The route from Cartagena to Santiago de Chile covers a distance of 4900 km, classifying it as a long-haul journey. This considerable distance means that travelers should anticipate a longer travel day, typically involving connecting flights to reach their destination.

How much is a round trip from Cartagena to Santiago de Chile

Regular price: $320 - $610

Prices from Cartagena to Santiago de Chile are currently below the regular range.

The regular price range for flights from Cartagena to Santiago de Chile is $320 to $610. The current lowest deal is $307 with B&H Airlines, for travel from Nov 5-Nov 16.

now $307

Low $320

High $610

The cheapest time to fly from Cartagena to Santiago de Chile

The cheapest month to fly from Cartagena to Santiago is December, with a median price of $264. The most expensive month is September, with a median price of $496. Prices are generally lower from April to December.

December

Cheapest

Flights from $264

September

Most Expensive

Flights from $496

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Cartagena to Santiago de Chile

Avianca

Last-minute flights going from Cartagena to Santiago de Chile

Thu, Aug 27

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$674

$657

One-way

Fri, Aug 28

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$679

$606

One-way

Fri, Aug 28

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$693

$666

One-way

Mon, Sep 7

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$418

One-way

Thu, Sep 10

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$377

$396

One-way

Thu, Sep 10

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$366

$396

One-way

Biggest price drops on these dates for flights from Cartagena to Santiago de Chile

4 nights

Sep 4 - Sep 8

$573 → $461

20%

4 nights

Sep 17 - Sep 21

$443 → $336

24%

6 nights

Sep 18 - Sep 24

$412 → $307

25%

2 nights

Dec 5 - Dec 7

$432 → $330

24%

Popular Airports to fly from Cartagena to Santiago de Chile

Cartagena - Santiago de Chile route insights

💸 Price insights

Recent fares are near the typical level

Recent fares from Cartagena to Santiago de Chile are near the typical level, with a median of $394.

📅 Best time to fly

Fly in December for the lowest prices

Historically, December offers the lowest median prices at $264, followed by November at $296.

⏱️ Flight duration

Flights typically take 12h 30m

The median flight duration from Cartagena to Santiago de Chile is 12 hours and 30 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Direct flights make up 0.1% of routes, with connecting flights typically having 1 stopover.

🏆 Airline highlight

Avianca offers direct flights

Avianca is one airline that has historically offered direct flights on this route.

🎯 Booking tip

Deals are frequent on this route

Historically, deals for flights from Cartagena to Santiago de Chile appear frequently.

Cartagena main airports to depart from

Rafael Núñez International (CTG)

Cheapest

Rafael Núñez International Airport is the cheapest option for flights from Cartagena to Santiago de Chile.

📍 ~10 km from city center (reachable by car)

💸 Flights from ~$366

Santiago de Chile main airports to arrive at

Comodoro Arturo Merino Benítez International (SCL)

Cheapest

Comodoro Arturo Merino Benítez International Airport is a key arrival point for flights to Santiago de Chile.

📍 ~15 km from Santiago de Chile city center (reachable by car)

💸 Flights from ~$366

Airports nearby Santiago de Chile used as alternative

Governor Francisco Gabrielli International (MDZ)

Consider this major international airport in Argentina for frequent connections, despite requiring an international border crossing.

📍 ~180 km from Santiago de Chile (reachable by car)

💸 Flights from ~$466

Business & First Class Flight Deals to Santiago de Chile

Discover luxury on the budget with premium cabin class on flights from Cartagena to Santiago de Chile.

Elite

Best Elite deals to Santiago de Chile

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From CTG

Elite

Nov 13

Santiago de Chile, Chile

94% AI deal score

$2,630

$1,338

Save $1,292

Copa Airlines

Business Class

From CTG

Elite

Nov 13

Santiago de Chile, Chile

94% AI deal score

$2,664

$1,338

Save $1,326

Copa Airlines

Business Class

From CTG

Elite

Nov 13

Santiago de Chile, Chile

94% AI deal score

$2,661

$1,338

Save $1,323

Copa Airlines

Business Class

From CTG

Elite

Nov 12

Santiago de Chile, Chile

94% AI deal score

$2,653

$1,338

Save $1,315

Copa Airlines

Business Class

From CTG

Elite

Nov 12

Santiago de Chile, Chile

94% AI deal score

$2,631

$1,338

Save $1,293

Copa Airlines

Business Class

From CTG

Elite

Oct 04

Santiago de Chile, Chile

94% AI deal score

$1,585

$894

Save $691

LATAM Chile

Business Class

From CTG

Elite

Oct 14

Santiago de Chile, Chile

94% AI deal score

$1,601

$894

Save $707

LATAM Chile

Business Class

From CTG

Elite

Sep 28

Santiago de Chile, Chile

94% AI deal score

$1,686

$894

Save $792

LATAM Chile

Business Class

From CTG

Elite

Sep 16

Santiago de Chile, Chile

94% AI deal score

$1,690

$915

Save $775

LATAM Chile

Business Class

From CTG

Elite

Sep 16

Santiago de Chile, Chile

94% AI deal score

$1,678

$915

Save $763

LATAM Chile

Business Class

From CTG

Elite

Sep 11

Santiago de Chile, Chile

93% AI deal score

$3,283

$1,296

Save $1,987

Avianca

Business Class

From CTG

Elite

Sep 02

Santiago de Chile, Chile

93% AI deal score

$3,280

$1,329

Save $1,951

Copa Airlines

Business Class

Frequently Asked Questions About Flights to Santiago de Chile

Historically, the lowest prices for flights from Cartagena to Santiago de Chile are found when booking between 14 and 27 days in advance. During this period, the average price was around $372. Booking 7-13 days out saw average prices of $380, while booking 60+ days in advance had an average price of $386. Prices tended to be higher for bookings made 28-59 days out, with an average of $631.

Across the trailing quarter, a good price for a flight from Cartagena to Santiago de Chile was considered to be $369 or less. The median price for this route was $394. Approximately 75% of fares were found at $433 or below during the same period, indicating that prices tend to be higher for a significant portion of bookings.

Historically, December has been the cheapest month to fly from Cartagena to Santiago de Chile, with a median price of $264. November also offered favorable prices, with a median of $296. The annual median price for this route was $394, suggesting that flying in these months can lead to significant savings compared to the yearly average.

Related routes

More routes from Cartagena

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Flights to Santiago de Chile from other cities

Cartagena to Santiago de Chile: Overview

Insights for flights from Cartagena to Santiago de Chile

How much is a round trip from Cartagena to Santiago de Chile

Regular price: $320 - $610

Prices from Cartagena to Santiago de Chile are currently below the regular range.

The regular price range for flights from Cartagena to Santiago de Chile is $320 to $610. The current lowest deal is $307 with B&H Airlines, for travel from Nov 5-Nov 16.

now $307

Low $320

High $610

The cheapest time to fly from Cartagena to Santiago de Chile

December

Cheapest

Flights from $264

September

Most Expensive

Flights from $496

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Cartagena to Santiago de Chile

Avianca

Last-minute flights going from Cartagena to Santiago de Chile

Thu, Aug 27

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$674

$657

One-way

Fri, Aug 28

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$679

$606

One-way

Fri, Aug 28

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$693

$666

One-way

Mon, Sep 7

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$418

One-way

Thu, Sep 10

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$377

$396

One-way

Thu, Sep 10

⌛ Last-Minute

CTG - Santiago de Chile

Cartagena (CTG) - Santiago de Chile (SCL)

B&H Airlines

$366

$396

One-way

Biggest price drops on these dates for flights from Cartagena to Santiago de Chile

4 nights

Sep 4 - Sep 8

$573 → $461

20%

4 nights

Sep 17 - Sep 21

$443 → $336

24%

6 nights

Sep 18 - Sep 24

$412 → $307

25%

2 nights

Dec 5 - Dec 7

$432 → $330

24%

Popular Airports to fly from Cartagena to Santiago de Chile

Cartagena - Santiago de Chile route insights

💸 Price insights

Recent fares are near the typical level

Recent fares from Cartagena to Santiago de Chile are near the typical level, with a median of $394.

📅 Best time to fly

Fly in December for the lowest prices

Historically, December offers the lowest median prices at $264, followed by November at $296.

⏱️ Flight duration

Flights typically take 12h 30m

The median flight duration from Cartagena to Santiago de Chile is 12 hours and 30 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Direct flights make up 0.1% of routes, with connecting flights typically having 1 stopover.

🏆 Airline highlight

Avianca offers direct flights

Avianca is one airline that has historically offered direct flights on this route.

🎯 Booking tip

Deals are frequent on this route

Historically, deals for flights from Cartagena to Santiago de Chile appear frequently.

Cartagena main airports to depart from

Rafael Núñez International (CTG)

Cheapest

Rafael Núñez International Airport is the cheapest option for flights from Cartagena to Santiago de Chile.

📍 ~10 km from city center (reachable by car)

💸 Flights from ~$366

Santiago de Chile main airports to arrive at

Comodoro Arturo Merino Benítez International (SCL)

Cheapest

Comodoro Arturo Merino Benítez International Airport is a key arrival point for flights to Santiago de Chile.

📍 ~15 km from Santiago de Chile city center (reachable by car)

💸 Flights from ~$366

Airports nearby Santiago de Chile used as alternative

Governor Francisco Gabrielli International (MDZ)

Consider this major international airport in Argentina for frequent connections, despite requiring an international border crossing.

Santiago de Chile, Chile

93% AI deal score

$3,280

$1,329

Save $1,951

Copa Airlines

Business Class

Frequently Asked Questions About Flights to Santiago de Chile

Cheap Flights from Cartagena to Santiago de Chile

Today’s best flight deals from Cartagena to Santiago de Chile

Cartagena to Santiago de Chile: Overview

Insights for flights from Cartagena to Santiago de Chile

How much is a round trip from Cartagena to Santiago de Chile

The cheapest time to fly from Cartagena to Santiago de Chile

Direct flights from Cartagena to Santiago de Chile

Last-minute flights going from Cartagena to Santiago de Chile

Biggest price drops on these dates for flights from Cartagena to Santiago de Chile

Popular Airports to fly from Cartagena to Santiago de Chile

Cartagena - Santiago de Chile route insights

Recent fares are near the typical level

Fly in December for the lowest prices

Flights typically take 12h 30m

Connecting flights are dominant

Avianca offers direct flights

Deals are frequent on this route

Cartagena main airports to depart from

Santiago de Chile main airports to arrive at

Airports nearby Santiago de Chile used as alternative

Business & First Class Flight Deals to Santiago de Chile

Best Elite deals to Santiago de Chile

Nov 13

Nov 13

Nov 13

Nov 12

Nov 12

Oct 04

Oct 14

Sep 28

Sep 16

Sep 16

Sep 11

Sep 02

Frequently Asked Questions About Flights to Santiago de Chile

How early should I book Cartagena to Santiago de Chile flights to get the cheapest price?

What's a cheap fare from Cartagena to Santiago de Chile?

What's the best month to fly from Cartagena to Santiago de Chile?

Are there direct flights from Cartagena to Santiago de Chile?

How long does it take to fly from Cartagena to Santiago de Chile?

Should I set a price alert for Cartagena to Santiago de Chile flights?

Related routes

More routes from Cartagena

Flights to Santiago de Chile from other cities

Cartagena to Santiago de Chile: Overview

Insights for flights from Cartagena to Santiago de Chile

How much is a round trip from Cartagena to Santiago de Chile

The cheapest time to fly from Cartagena to Santiago de Chile

Direct flights from Cartagena to Santiago de Chile

Last-minute flights going from Cartagena to Santiago de Chile

Biggest price drops on these dates for flights from Cartagena to Santiago de Chile

Popular Airports to fly from Cartagena to Santiago de Chile

Cartagena - Santiago de Chile route insights

Recent fares are near the typical level

Fly in December for the lowest prices

Flights typically take 12h 30m

Connecting flights are dominant

Avianca offers direct flights

Deals are frequent on this route

Cartagena main airports to depart from

Santiago de Chile main airports to arrive at

Airports nearby Santiago de Chile used as alternative

Business & First Class Flight Deals to Santiago de Chile

Best Elite deals to Santiago de Chile

Nov 13

Nov 13

Nov 13

Nov 12

Nov 12

Oct 04

Oct 14

Sep 28

Sep 16

Sep 16

Sep 11

Sep 02

Frequently Asked Questions About Flights to Santiago de Chile

How early should I book Cartagena to Santiago de Chile flights to get the cheapest price?

What's a cheap fare from Cartagena to Santiago de Chile?

What's the best month to fly from Cartagena to Santiago de Chile?