Are direct flights from Denver to Greenville always the best option?

Direct flights are often the most convenient choice, saving time and avoiding layovers. However, they are not always the cheapest option. Flights with one or more connections may sometimes offer lower fares, depending on the route and demand.

Can flexible travel dates help on Denver to Greenville flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying on weekdays or during off-peak seasons often results in more affordable fares compared to weekends or popular holiday periods. Adjusting your departure or return by a few days may reveal better deals.

What extra costs should I check before booking Denver to Greenville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. These additional fees can add to the total cost of your trip.

Flights From Denver

To Greenville

Cheap Flights from Denver to Greenville

Browse current best options from Denver. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Denver

RatePunk searches hundreds of travel sites at once for deals on flights to Greenville

Prices updated 7 days ago

482 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)

Today’s best flight deals from Denver to Greenville

Explore current cheapest deals departing from Denver to Greenville

2027-01-06 – 2027-01-11
DEN - Greenville
77% AI deal score
$304
$218
Round trip
2027-01-06 – 2027-01-25
DEN - Greenville
70% AI deal score
$263
$221
Round trip
2027-01-06 – 2027-02-01
DEN - Greenville
70% AI deal score
$262
$221
Round trip
2027-01-13 – 2027-02-08
DEN - Greenville
70% AI deal score
$262
$222
Round trip
2027-01-13 – 2027-01-25
DEN - Greenville
71% AI deal score
$273
$222
Round trip
2027-01-13 – 2027-02-01
DEN - Greenville
70% AI deal score
$263
$222
Round trip
2027-01-27 – 2027-02-08
DEN - Greenville
75% AI deal score
$279
$222
Round trip
2027-01-27 – 2027-02-01
DEN - Greenville
78% AI deal score
$312
$222
Round trip
2027-02-03 – 2027-02-08
DEN - Greenville
79% AI deal score
$330
$222
Round trip
2027-01-07 – 2027-01-11
DEN - Greenville
75% AI deal score
$304
$230
Round trip

Denver to Greenville: Overview

Insights for flights from Denver to Greenville

For travelers looking for cheap flights from Denver to Greenville, the most affordable month to fly is typically March, with a median fare of $397. Other cost-effective options include August and June, both showing a median fare of $409. Planning your trip around these months can help secure better prices for your journey.

Right now, fares for flights from Denver to Greenville typically range from $409–$484, with a median price of $419. Current fares are significantly below the typical level, indicating a favorable time to consider booking. Approximately 6% of recent fares have been classified as a good price, suggesting that while deals exist, they are not exceedingly common.

Most itineraries for this route involve connections, as only 16% of recent fares were for non-stop flights. For the majority of journeys, you can expect to make 2 connections. This means that while direct flights from Denver to Greenville are available, they represent a smaller portion of the overall flight options.

A typical journey from Denver to Greenville, including connections, takes about 6h 59m. If you find a direct flight, the non-stop travel time is approximately 3h 8m. Given that most itineraries involve stopovers, the overall travel duration tends to be longer than the direct flight time.

The distance between Denver and Greenville is 2053 km, classifying this as a medium-haul route. This distance typically involves several hours of flight time, often with at least one stop, making it a significant journey across the country.

How much is a round trip from Denver to Greenville

Regular price: $274 - $415

Prices for flights from Denver to Greenville are currently below the regular range.

The regular price range for flights from Denver to Greenville is typically between $274 and $415. The current lowest deal is $220 with Frontier Airlines for travel from Feb 3-Feb 5.

now $220

Low $274

High $415

The cheapest time to fly from Denver to Greenville

The cheapest month to fly from Denver to Greenville is January, with a median price of $269. The most expensive month is December, with a median price of $480. Prices are generally lower from January to November.

January

Cheapest

Flights from $269

December

Most Expensive

Flights from $480

Jan

Feb

Mar

Oct

Nov

Dec

Direct flights from Denver to Greenville

Frontier Airlines

Breeze Airways

Last-minute flights going from Denver to Greenville

Fri, Oct 30

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$425

$934

One-way

Mon, Nov 2

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$373

$777

One-way

Fri, Nov 6

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

United Airlines

$257

$549

One-way

Fri, Nov 6

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$339

$676

One-way

Mon, Nov 9

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines

$381

$424

One-way

Mon, Nov 9

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$337

$648

One-way

Biggest price drops on these dates for flights from Denver to Greenville

2 nights

Nov 14 - Nov 16

$382 → $294

23%

5 nights

Jan 27 - Feb 1

$313 → $227

27%

4 nights

Jan 28 - Feb 1

$313 → $231

26%

9 nights

Jan 23 - Feb 1

$293 → $229

22%

Popular Airports to fly from Denver to Greenville

Denver - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares for flights from Denver to Greenville are below the typical level at $220.

📅 Best time to fly

March, August, and June offer lower median prices

Historically, March ($397), August ($409), and June ($409) have offered lower median prices.

⏱️ Flight duration

Direct flights take 3h 8m

Direct flights from Denver to Greenville typically take 3 hours and 8 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights make up 84% of routes, with a median of 2 stopovers.

🏆 Airline highlight

United Airlines offers direct flights

United Airlines has offered direct flights on this route, with 1 direct deal found recently.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Denver to Greenville are historically rare.

Denver main airports to depart from

Denver International (DEN)

Cheapest

Denver International Airport is a convenient choice for flights from Denver to Greenville.

📍 ~30 km from city center (reachable by car or train)

💸 Flights from ~$263

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival choice for flights from Denver to Greenville.

📍 ~17 km from city center (reachable by car)

💸 Flights from ~$207

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International is a major international hub with extensive direct flight options globally.

📍 ~135 km from Greenville (reachable by car, but heavy traffic on I-85 can significantly increase travel time).

💸 Flights from ~$246

Business & First Class Flight Deals to Greenville

Discover luxury on the budget with premium cabin class on flights from Denver to Greenville.

Elite

Best Elite deals to Greenville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From DEN

Elite

Nov 26

Greenville, United States

39% AI deal score

$4,992

Air Canada, +1

Business Class

From DEN

Elite

Nov 26

Greenville, United States

39% AI deal score

$5,081

Air Canada, +1

Business Class

From DEN

Elite

Nov 26

Greenville, United States

39% AI deal score

$5,248

Air Canada, +1

Business Class

From DEN

Elite

Dec 31

Greenville, United States

39% AI deal score

$5,337

Air Canada, +1

Business Class

From DEN

Elite

Dec 29

Greenville, United States

39% AI deal score

$5,357

Air Canada, +1

Business Class

From DEN

Elite

Dec 31

Greenville, United States

39% AI deal score

$5,359

Air Canada, +1

Business Class

From DEN

Elite

Dec 31

Greenville, United States

39% AI deal score

$5,441

Air Canada, +1

Business Class

From DEN

Elite

Nov 26

Greenville, United States

38% AI deal score

$5,293

Air Canada, +1

Business Class

From DEN

Elite

Dec 29

Greenville, United States

38% AI deal score

$5,316

Air Canada, +1

Business Class

From DEN

Elite

Dec 31

Greenville, United States

38% AI deal score

$5,317

Air Canada, +1

Business Class

From DEN

Elite

Dec 29

Greenville, United States

38% AI deal score

$5,336

Air Canada, +1

Business Class

From DEN

Elite

Dec 20

Greenville, United States

38% AI deal score

$5,336

Air Canada, +1

Business Class

Frequently Asked Questions About Flights to Greenville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can often reveal better deals. Setting up price alerts may also notify you when fares drop.

Booking flights in advance, often several weeks or months before your intended travel date, may result in lower prices. However, prices can fluctuate, so monitoring fares over time can be beneficial. Last-minute bookings usually carry a higher cost.

Comparing nearby airports can sometimes offer more flight options or potentially lower fares. While it may require additional travel to and from these airports, the savings could be significant. Always factor in the total cost and convenience when considering this option.

Related routes

More routes from Denver

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Flights to Greenville from other cities

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Denver to Greenville: Overview

Insights for flights from Denver to Greenville

How much is a round trip from Denver to Greenville

Regular price: $274 - $415

Prices for flights from Denver to Greenville are currently below the regular range.

The regular price range for flights from Denver to Greenville is typically between $274 and $415. The current lowest deal is $220 with Frontier Airlines for travel from Feb 3-Feb 5.

now $220

Low $274

High $415

The cheapest time to fly from Denver to Greenville

January

Cheapest

Flights from $269

December

Most Expensive

Flights from $480

Jan

Feb

Mar

Oct

Nov

Dec

Direct flights from Denver to Greenville

Frontier Airlines

Breeze Airways

Last-minute flights going from Denver to Greenville

Fri, Oct 30

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$425

$934

One-way

Mon, Nov 2

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$373

$777

One-way

Fri, Nov 6

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

United Airlines

$257

$549

One-way

Fri, Nov 6

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$339

$676

One-way

Mon, Nov 9

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines

$381

$424

One-way

Mon, Nov 9

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$337

$648

One-way

Biggest price drops on these dates for flights from Denver to Greenville

2 nights

Nov 14 - Nov 16

$382 → $294

23%

5 nights

Jan 27 - Feb 1

$313 → $227

27%

4 nights

Jan 28 - Feb 1

$313 → $231

26%

9 nights

Jan 23 - Feb 1

$293 → $229

22%

Popular Airports to fly from Denver to Greenville

Denver - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares for flights from Denver to Greenville are below the typical level at $220.

📅 Best time to fly

March, August, and June offer lower median prices

Historically, March ($397), August ($409), and June ($409) have offered lower median prices.

⏱️ Flight duration

Direct flights take 3h 8m

Direct flights from Denver to Greenville typically take 3 hours and 8 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights make up 84% of routes, with a median of 2 stopovers.

🏆 Airline highlight

United Airlines offers direct flights

United Airlines has offered direct flights on this route, with 1 direct deal found recently.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Denver to Greenville are historically rare.

Denver main airports to depart from

Denver International (DEN)

Cheapest

Denver International Airport is a convenient choice for flights from Denver to Greenville.

📍 ~30 km from city center (reachable by car or train)

💸 Flights from ~$263

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival choice for flights from Denver to Greenville.

📍 ~17 km from city center (reachable by car)

💸 Flights from ~$207

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International is a major international hub with extensive direct flight options globally.

📍 ~135 km from Greenville (reachable by car, but heavy traffic on I-85 can significantly increase travel time).

💸 Flights from ~$246

Greenville, United States

38% AI deal score

$5,336

Air Canada, +1

Business Class

Frequently Asked Questions About Flights to Greenville

Cheap Flights from Denver to Greenville

Today’s best flight deals from Denver to Greenville

Denver to Greenville: Overview

Insights for flights from Denver to Greenville

How much is a round trip from Denver to Greenville

The cheapest time to fly from Denver to Greenville

Direct flights from Denver to Greenville

Last-minute flights going from Denver to Greenville

Biggest price drops on these dates for flights from Denver to Greenville

Popular Airports to fly from Denver to Greenville

Denver - Greenville route insights

Recent fares are below the typical level

March, August, and June offer lower median prices

Direct flights take 3h 8m

Connecting flights are dominant

United Airlines offers direct flights

Deals are rare for this route

Denver main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Nov 26

Nov 26

Nov 26

Dec 31

Dec 29

Dec 31

Dec 31

Nov 26

Dec 29

Dec 31

Dec 29

Dec 20

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Denver to Greenville?

When should I book flights from Denver to Greenville?

Should I compare nearby airports for flights from Denver to Greenville?

Are direct flights from Denver to Greenville always the best option?

Can flexible travel dates help on Denver to Greenville flights?

What extra costs should I check before booking Denver to Greenville flights?

Related routes

More routes from Denver

Flights to Greenville from other cities

Denver to Greenville: Overview

Insights for flights from Denver to Greenville

How much is a round trip from Denver to Greenville

The cheapest time to fly from Denver to Greenville

Direct flights from Denver to Greenville

Last-minute flights going from Denver to Greenville

Biggest price drops on these dates for flights from Denver to Greenville

Popular Airports to fly from Denver to Greenville

Denver - Greenville route insights

Recent fares are below the typical level

March, August, and June offer lower median prices

Direct flights take 3h 8m

Connecting flights are dominant

United Airlines offers direct flights

Deals are rare for this route

Denver main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Nov 26

Nov 26

Nov 26

Dec 31

Dec 29

Dec 31

Dec 31

Nov 26

Dec 29

Dec 31

Dec 29

Dec 20

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Denver to Greenville?

When should I book flights from Denver to Greenville?

Should I compare nearby airports for flights from Denver to Greenville?