Are direct flights from Denver to Greenville always the best option?

Direct flights offer convenience and save time by avoiding layovers. However, connecting flights can sometimes be more affordable, especially if you are willing to accept a longer travel duration. The 'best' option often depends on your priorities regarding cost versus travel time.

Can flexible travel dates help on Denver to Greenville flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying a day or two earlier or later can sometimes result in substantial savings. Weekday travel often presents more budget-friendly options compared to weekend travel.

What extra costs should I check before booking Denver to Greenville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Understanding these additional expenses can help you budget accurately for your trip.

Flights From Denver

To Greenville

Cheap Flights from Denver to Greenville

Browse current best options from Denver. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Denver

RatePunk searches hundreds of travel sites at once for deals on flights to Greenville

Prices updated today

462 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 15, 2026.)

Today’s best flight deals from Denver to Greenville

Explore current cheapest deals departing from Denver to Greenville

2026-11-03 – 2026-11-16
DEN - Greenville
75% AI deal score
$321
$253
Round trip
2026-11-03 – 2026-11-09
DEN - Greenville
77% AI deal score
$353
$253
Round trip
2026-11-10 – 2026-11-16
DEN - Greenville
78% AI deal score
$358
$253
Round trip
2026-11-14 – 2026-11-16
DEN - Greenville
78% AI deal score
$373
$254
Round trip
2026-11-04 – 2026-11-09
DEN - Greenville
78% AI deal score
$364
$254
Round trip
2026-10-27 – 2026-11-09
DEN - Greenville
75% AI deal score
$325
$254
Round trip
2026-11-04 – 2026-11-16
DEN - Greenville
71% AI deal score
$321
$255
Round trip
2026-10-27 – 2026-11-16
DEN - Greenville
70% AI deal score
$311
$255
Round trip
2026-11-07 – 2026-11-09
DEN - Greenville
78% AI deal score
$372
$259
Round trip
2026-11-07 – 2026-11-13
DEN - Greenville
77% AI deal score
$355
$259
Round trip

Denver to Greenville: Overview

Insights for flights from Denver to Greenville

For those seeking cheap flights from Denver to Greenville, the most affordable month to fly is typically March, with a median fare of $397. Other cost-effective options include August and June, both showing median fares of $409. Planning your trip around these months can help secure better prices for your journey.

Right now, fares for flights from Denver to Greenville typically range from $409–$484, with a median price of $419. Current fares are significantly below the typical level, indicating a favorable time to consider booking. Approximately 6% of recent fares have been classified as a good price, suggesting that while deals appear regularly, finding the absolute lowest prices requires some flexibility.

Most itineraries from Denver to Greenville involve connections, with only 16% of recent fares being non-stop. For the majority of flights that are not direct, travelers can expect to make 2 stopovers. This means that while direct options are available, connecting flights are a common part of the travel experience on this route.

A typical journey from Denver to Greenville, including connections, takes approximately 6h 59m. For the less frequent direct flights from Denver to Greenville, the travel time is considerably shorter, at around 3h 8m. When planning your trip, factor in the additional time for connecting itineraries, as these represent the majority of available flights.

How much is a round trip from Denver to Greenville

Regular price: $296 - $442

Prices for flights from Denver to Greenville are currently below the regular range.

The regular price range for this route is $296 to $442. The current lowest deal is $252 with Frontier Airlines, for travel from Nov 4-Nov 9.

now $252

Low $296

High $442

The cheapest time to fly from Denver to Greenville

The cheapest month to fly from Denver to Greenville is December, with a median price of $328. The most expensive month is October, with a median price of $502. Prices are generally lower from January to December.

December

Cheapest

Flights from $328

October

Most Expensive

Flights from $502

Jan

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Denver to Greenville

United Airlines

Last-minute flights going from Denver to Greenville

Sat, Sep 26

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

United Airlines

$257

$418

One-way

Thu, Oct 1

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines

$379

$374

One-way

Sat, Oct 3

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines

$364

$279

One-way

Sat, Oct 3

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines

$391

$306

One-way

Sat, Oct 3

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

United Airlines

$212

$449

One-way

Mon, Oct 5

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Frontier Airlines, Breeze Airways

$311

$341

One-way

Biggest price drops on these dates for flights from Denver to Greenville

5 nights

Nov 4 - Nov 9

$364 → $272

25%

3 nights

Oct 3 - Oct 6

$391 → $307

22%

6 nights

Nov 3 - Nov 9

$353 → $270

23%

7 nights

Oct 3 - Oct 10

$364 → $281

23%

Popular Airports to fly from Denver to Greenville

Denver - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares for Denver to Greenville are below the typical level at $252.

📅 Best time to fly

March, August, and June offer lower median prices

Historically, March ($397), August ($409), and June ($409) show the lowest median prices.

⏱️ Flight duration

Direct flights take 3h 8m; connecting flights average 6h 59m

Direct flights from Denver to Greenville typically take 3h 8m, while connecting flights average 6h 59m.

✈️ Airlines & availability

Connecting flights are dominant for this route

Only 16% of flights are direct, with most connecting flights having 2 stopovers.

🏆 Airline highlight

United Airlines offers direct flights

United Airlines is a provider of direct flights on the Denver to Greenville route.

🎯 Booking tip

Deals appear regularly for this route

Deals for flights from Denver to Greenville appear regularly, offering opportunities to save.

Denver main airports to depart from

Denver International (DEN)

Cheapest

Denver International is a key departure point for flights from Denver to Greenville.

📍 ~30 km from city center (reachable by car or train)

💸 Flights from ~$272

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival option for flights from Denver.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~$270

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

This major international hub offers extensive direct flight options, ideal for global connections.

📍 ~150 km from Greenville (reachable by car, but expect heavy traffic on I-85).

💸 Flights from ~$183

Business & First Class Flight Deals to Greenville

$889

Save $410

United Airlines

Business Class

Frequently Asked Questions About Flights to Greenville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you identify better deals. Sometimes, flying on weekdays or during off-peak seasons may offer lower fares.

Booking flights in advance often provides more competitive prices, especially for popular routes. However, prices can fluctuate, so it's useful to monitor fare trends. Setting up price alerts can notify you when prices drop for your desired travel period.

Comparing nearby airports at both your origin and destination can sometimes reveal more economical flight options. While it might involve additional ground transportation, the savings on airfare could be significant. Always factor in the total cost and convenience when considering this approach.

Denver to Greenville: Overview

Insights for flights from Denver to Greenville

How much is a round trip from Denver to Greenville

Regular price: $296 - $442

Prices for flights from Denver to Greenville are currently below the regular range.

The regular price range for this route is $296 to $442. The current lowest deal is $252 with Frontier Airlines, for travel from Nov 4-Nov 9.

now $252

Low $296

High $442

The cheapest time to fly from Denver to Greenville

December

Cheapest

Flights from $328

October

Most Expensive

Flights from $502

Jan

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec