Are direct flights from Denver to Greenville always the best option?

Direct flights often offer convenience and save travel time, but they are not always the cheapest option. Flights with layovers can sometimes be more affordable, especially if you are flexible with your schedule. Consider your priorities, such as cost versus travel duration, when making your choice.

Can flexible travel dates help on Denver to Greenville flights?

Yes, being flexible with your travel dates can significantly impact the price of your flight. Traveling during off-peak seasons or on weekdays often results in lower fares compared to weekends or holidays. Adjusting your departure or return by a few days may reveal more budget-friendly options.

What extra costs should I check before booking Denver to Greenville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factoring these into your total budget can help avoid surprises.

Flights From Denver

To Greenville

Cheap Flights from Denver to Greenville

Browse current best options from Denver. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Denver

RatePunk searches hundreds of travel sites at once for deals on flights to Greenville

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Denver to Greenville

Explore current cheapest deals departing from Denver to Greenville

2026-08-26 – 2026-08-31
DEN - Greenville
82% AI deal score
$408
$220
Round trip
2026-08-19 – 2026-08-25
DEN - Greenville
82% AI deal score
$400
$231
Round trip
2026-08-27 – 2026-08-31
DEN - Greenville
82% AI deal score
$421
$232
Round trip
2026-09-17 – 2026-09-21
DEN - Greenville
79% AI deal score
$385
$246
Round trip
2026-08-27 – 2026-08-30
DEN - Greenville
80% AI deal score
$421
$264
Round trip
2026-08-18 – 2026-08-24
DEN - Greenville
79% AI deal score
$402
$266
Round trip
2026-08-18 – 2026-08-31
DEN - Greenville
76% AI deal score
$356
$266
Round trip
2026-08-25 – 2026-08-31
DEN - Greenville
79% AI deal score
$396
$266
Round trip
2026-08-18 – 2026-08-21
DEN - Greenville
80% AI deal score
$429
$267
Round trip
2026-09-21 – 2026-09-28
DEN - Greenville
77% AI deal score
$370
$267
Round trip

Denver to Greenville: Overview

Insights for flights from Denver to Greenville

March is typically the cheapest month to fly from Denver to Greenville, with a median fare of $397. Other affordable times to consider are August and June, both with median fares of $409. Planning your trip around these months can help you find more economical options for your journey.

For those seeking cheap flights from Denver to Greenville, fares typically range from $409–$484, with a median of $419. Right now, current fares are significantly below the typical level. Only 6% of recent fares were classified as a good price, indicating that finding deals can sometimes be challenging on this route. New deals show up several times a week, so consistent monitoring can be beneficial.

Most itineraries for flights from Denver to Greenville connect at least once, with only 16% of recent fares being non-stop. When connections are involved, the typical number of stopovers is 2. This means you should expect a journey that includes at least one stop on most flights.

A typical journey from Denver to Greenville takes approximately 6h 59m, including connections. For direct flights from Denver to Greenville, the non-stop flight time is 3h 8m. However, since most itineraries involve connections, the overall travel duration is generally longer.

The distance between Denver and Greenville is 2053 km, classifying this as a medium-haul route. This distance typically translates to a flight experience that is longer than a short regional hop but shorter than an intercontinental journey.

How much is a round trip from Denver to Greenville

Regular price: $327 - $445

Prices for flights from Denver to Greenville are currently below the regular range.

The regular price range for flights from Denver to Greenville is $327 to $445. The current lowest deal is $220 with Frontier Airlines for travel from Aug 26-Aug 31.

now $220

Low $327

High $445

The cheapest time to fly from Denver to Greenville

The cheapest month to fly from Denver to Greenville is December, with a median price of $328. The most expensive month is October, with a median price of $502. Prices are generally lower from January to December.

December

Cheapest

Flights from $328

October

Most Expensive

Flights from $502

Jan

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Denver to Greenville

United Airlines

Last-minute flights going from Denver to Greenville

Sat, Aug 1

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

American Airlines

$638

$497

One-way

Mon, Aug 3

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Southwest Airlines

$522

$438

One-way

Wed, Aug 5

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

American Airlines

$436

$358

One-way

Wed, Aug 5

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

United Airlines

$291

$368

One-way

Wed, Aug 5

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

United Airlines

$492

$388

One-way

Wed, Aug 5

⌛ Last-Minute

DEN - Greenville

Denver (DEN) - Greenville (GSP)

Southwest Airlines

$496

$438

One-way

Biggest price drops on these dates for flights from Denver to Greenville

5 nights

Aug 26 - Aug 31

$408 → $220

46%

4 nights

Aug 27 - Aug 31

$417 → $232

44%

6 nights

Aug 19 - Aug 25

$400 → $231

42%

3 nights

Aug 18 - Aug 21

$425 → $267

37%

Popular Airports to fly from Denver to Greenville

Denver - Greenville route insights

💸 Price insights

Recent fares are below the typical level at $220.

Recent fares from Denver to Greenville are below the typical level, with deals as low as $220.

📅 Best time to fly

Historically, December is the cheapest month to fly at $328.

Historically, December offers the lowest median prices at $328 for flights from Denver to Greenville.

⏱️ Flight duration

Direct flights take 3h 8m; connecting flights average 6h 59m.

Direct flights from Denver to Greenville typically take 3h 8m, while connecting flights average 6h 59m.

✈️ Airlines & availability

United Airlines offers direct flights; 16% of recent flights are direct.

United Airlines has offered direct flights. Historically, 16% of flights on this route have been direct.

🏆 Airline highlight

Frontier Airlines had a recent deal for $220.

Frontier Airlines offered a recent deal from Denver to Greenville for $220.

🎯 Booking tip

Good deals appear regularly for this route.

Deals for flights from Denver to Greenville appear regularly, offering opportunities for savings.

Denver main airports to depart from

Denver International (DEN)

Cheapest

Denver International Airport is a good option for flights from Denver to Greenville.

📍 ~30 km from city center (reachable by car or train)

💸 Flights from ~$244

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival choice for flights from Denver.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~$218

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International offers extensive direct flight options globally, serving as a major international hub.

📍 ~150 km from Greenville (reachable by car, though heavy I-85 traffic can increase travel time).

💸 Flights from ~$206

Business & First Class Flight Deals to Greenville

85% AI deal score

$1,434

$814

Save $620

Frequently Asked Questions About Flights to Greenville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you identify better deals. Setting up price alerts may notify you when fares drop for your desired route.

Booking flights in advance, often several weeks or months before your trip, can sometimes result in lower prices. However, prices can fluctuate, so monitoring fares over time may help you decide the optimal booking moment. Mid-week bookings are also sometimes associated with better deals.

Comparing nearby airports at both your origin and destination can sometimes uncover more economical flight options. While it may add to your ground travel time, the potential savings on airfare can be significant. Always factor in the cost and convenience of transportation to and from alternative airports.

Denver to Greenville: Overview

Insights for flights from Denver to Greenville

How much is a round trip from Denver to Greenville

Regular price: $327 - $445

Prices for flights from Denver to Greenville are currently below the regular range.

The regular price range for flights from Denver to Greenville is $327 to $445. The current lowest deal is $220 with Frontier Airlines for travel from Aug 26-Aug 31.

now $220

Low $327

High $445

The cheapest time to fly from Denver to Greenville

December

Cheapest

Flights from $328

October

Most Expensive

Flights from $502

Jan

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec