Are direct flights from Rome to Greenville always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers, but they are not always the most budget-friendly choice. Flights with one or more connections can sometimes be significantly cheaper. Consider your priorities for cost versus travel duration when making your decision.

Can flexible travel dates help on Rome to Greenville flights?

Yes, being flexible with your travel dates can often lead to finding more affordable flight options. Prices can vary considerably even within the same week, so adjusting your departure or return by a few days may result in savings. Tools that show a calendar view of prices can be very useful.

What extra costs should I check before booking Rome to Greenville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Being aware of these additional fees can help you calculate the true total cost of your journey.

Flights From Rome

To Greenville

Cheap Flights from Rome to Greenville

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Greenville

Prices updated 1 day ago

462 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 15, 2026.)

Today’s best flight deals from Rome to Greenville

Explore current cheapest deals departing from Rome to Greenville

2026-10-22 – 2026-10-29
ROM - Greenville
91% AI deal score
887 €
649 €
Round trip
2026-10-14 – 2026-10-19
ROM - Greenville
91% AI deal score
922 €
654 €
Round trip
2026-10-14 – 2026-10-20
ROM - Greenville
91% AI deal score
897 €
657 €
Round trip
2026-10-31 – 2026-11-10
ROM - Greenville
80% AI deal score
849 €
763 €
Round trip
2027-02-25 – 2027-03-06
ROM - Greenville
81% AI deal score
865 €
767 €
Round trip
2026-11-21 – 2026-11-30
ROM - Greenville
78% AI deal score
844 €
783 €
Round trip
2026-11-04 – 2026-11-30
ROM - Greenville
75% AI deal score
813 €
801 €
Round trip
2026-10-02 – 2026-10-18
ROM - Greenville
74% AI deal score
840 €
952 €
Round trip
2026-10-24 – 2026-10-26
ROM - Greenville
75% AI deal score
936 €
960 €
Round trip
2026-09-25 – 2026-09-27
ROM - Greenville
77% AI deal score
1,023 €
969 €
Round trip

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

For flights from Rome to Greenville, fares typically range from $891–$1483, with a median of $1294. Right now, fares are below the typical level, and only 3% of recent fares were classified as a good price. New deals for this route are infrequent, so setting up a price alert can be beneficial.

When considering cheap flights from Rome to Greenville, the most affordable month to fly is April, with a median fare of $1029. Other relatively cheaper months include July, with a median of $1241, and August, where the median fare is $1271.

A typical journey from Rome to Greenville takes approximately 44h 40m, including connections. This is a long-haul route, covering a distance of 7839 km. Most itineraries on this route connect at least once, with the median number of stopovers for connecting flights being 2. There are currently no direct flights from Rome to Greenville.

How much is a round trip from Rome to Greenville

Regular price: €766 - €1,295

Prices for flights from Rome to Greenville are currently below the regular range.

The regular price range for flights from Rome to Greenville is typically between 766 EUR and 1295 EUR. The current lowest deal is 649 EUR with Deutsche Luft Hansa, for travel from Oct 22-Oct 29.

now 649 €

Low 766 €

High 1,295 €

The cheapest time to fly from Rome to Greenville

The cheapest month to fly from Rome to Greenville is April, with a median price of $1029. The most expensive month is June, with a median price of $1342. Generally, prices are lower from April to August.

April

Cheapest

Flights from 1,029 €

June

Most Expensive

Flights from 1,342 €

Apr

May

Jun

Jul

Aug

Direct flights from Rome to Greenville

Breeze Airways

Norse Atlantic UK

Aero Services Executive

KLM

Last-minute flights going from Rome to Greenville

Mon, Sep 28

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Norse Atlantic Airways, JetBlue Airways, Breeze Airways

833 €

1,094 €

One-way

Wed, Oct 14

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Air France

901 €

656 €

One-way

Sun, Nov 1

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

909 €

1,041 €

One-way

Sun, Nov 1

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

908 €

1,041 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

909 €

1,041 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

910 €

1,489 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

6 nights

Oct 14 - Oct 20

897 € → 657 €

27%

30 nights

Dec 12 - Jan 11

941 € → 725 €

23%

13 nights

Dec 1 - Dec 14

949 € → 744 €

22%

9 nights

Feb 25 - Mar 6

865 € → 767 €

11%

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are currently below the typical level at $649.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly from Rome to Greenville, with a median price of $1029.

⏱️ Flight duration

Typical flight time is 44h 40m

The typical flight duration from Rome to Greenville is 44 hours and 40 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant on this route, typically with 2 stopovers.

🏆 Airline highlight

Deutsche Luft Hansa offers a deal

Deutsche Luft Hansa has a recent deal for $649 from Rome to Greenville.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Rome to Greenville are rare, so consider booking when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient departure point for flights from Rome to Greenville.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€639

Ciampino–G. B. Pastine International (CIA)

Ciampino–G. B. Pastine International offers another option for your journey from Rome to Greenville.

📍 ~14 km from Rome city center (reachable by car or bus).

💸 Flights from ~€746

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival option for flights from Rome to Greenville.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~€639

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International is a major international hub with extensive direct flight options, a good alternative for Greenville.

📍 ~150 km from Greenville (reachable by car, but expect heavy traffic).

💸 Flights from ~€635

Business & First Class Flight Deals to Greenville

Discover luxury on the budget with premium cabin class on flights from Rome to Greenville.

Elite

Best Elite deals to Greenville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Dec 01

Greenville, United States

75% AI deal score

$2,673

Iberia Airlines, +1

Business Class

From FCO

Elite

Nov 30

Greenville, United States

75% AI deal score

$2,703

Iberia Airlines, +1

Business Class

From FCO

Elite

Nov 12

Greenville, United States

75% AI deal score

$2,709

Iberia Airlines, +1

Business Class

From FCO

Elite

Dec 02

Greenville, United States

75% AI deal score

$2,778

Iberia Airlines, +1

Business Class

From FCO

Elite

Dec 03

Greenville, United States

75% AI deal score

$2,781

Iberia Airlines, +1

Business Class

From FCO

Elite

Nov 09

Greenville, United States

75% AI deal score

$2,786

Iberia Airlines, +1

Business Class

From FCO

Elite

Nov 14

Greenville, United States

75% AI deal score

$2,910

Iberia Airlines, +1

Business Class

From FCO

Elite

Oct 15

Greenville, United States

74% AI deal score

$2,919

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 14

Greenville, United States

74% AI deal score

$2,944

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 20

Greenville, United States

74% AI deal score

$2,957

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 15

Greenville, United States

74% AI deal score

$2,969

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 15

Greenville, United States

74% AI deal score

$2,969

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Greenville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you identify better deals. Sometimes, flying on weekdays or during off-peak seasons may result in lower fares.

Booking flights in advance often provides more competitive prices, though last-minute deals can sometimes appear. It's usually beneficial to monitor price trends for your desired travel period. Many travelers find that booking a few months before departure can offer a good balance.

Comparing nearby airports at both your origin and destination can sometimes reveal more economical flight options. While it might add to your ground travel time, the potential savings on airfare can be significant. Always factor in the cost and convenience of transportation to and from alternative airports.

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

Regular price: €766 - €1,295

Prices for flights from Rome to Greenville are currently below the regular range.

The regular price range for flights from Rome to Greenville is typically between 766 EUR and 1295 EUR. The current lowest deal is 649 EUR with Deutsche Luft Hansa, for travel from Oct 22-Oct 29.

now 649 €

Low 766 €

High 1,295 €

The cheapest time to fly from Rome to Greenville

April

Cheapest

Flights from 1,029 €

June

Most Expensive

Flights from 1,342 €

Apr

May

Jun

Jul

Aug

Direct flights from Rome to Greenville

Breeze Airways

Norse Atlantic UK

Aero Services Executive

KLM

Last-minute flights going from Rome to Greenville

Mon, Sep 28

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Norse Atlantic Airways, JetBlue Airways, Breeze Airways

833 €

1,094 €

One-way

Wed, Oct 14

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Air France

901 €

656 €

One-way

Sun, Nov 1

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

909 €

1,041 €

One-way

Sun, Nov 1

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

908 €

1,041 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

909 €

1,041 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

910 €

1,489 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

6 nights

Oct 14 - Oct 20

897 € → 657 €

27%

30 nights

Dec 12 - Jan 11

941 € → 725 €

23%

13 nights

Dec 1 - Dec 14

949 € → 744 €

22%

9 nights

Feb 25 - Mar 6

865 € → 767 €

11%

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are currently below the typical level at $649.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly from Rome to Greenville, with a median price of $1029.

⏱️ Flight duration

Typical flight time is 44h 40m

The typical flight duration from Rome to Greenville is 44 hours and 40 minutes.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant on this route, typically with 2 stopovers.

🏆 Airline highlight

Deutsche Luft Hansa offers a deal

Deutsche Luft Hansa has a recent deal for $649 from Rome to Greenville.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Rome to Greenville are rare, so consider booking when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient departure point for flights from Rome to Greenville.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€639

Ciampino–G. B. Pastine International (CIA)

Ciampino–G. B. Pastine International offers another option for your journey from Rome to Greenville.

📍 ~14 km from Rome city center (reachable by car or bus).

💸 Flights from ~€746

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival option for flights from Rome to Greenville.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~€639

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International is a major international hub with extensive direct flight options, a good alternative for Greenville.

📍 ~150 km from Greenville (reachable by car, but expect heavy traffic).

💸 Flights from ~€635

Greenville, United States

74% AI deal score

$2,969

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Greenville

Cheap Flights from Rome to Greenville

Today’s best flight deals from Rome to Greenville

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Typical flight time is 44h 40m

Connecting flights are dominant

Deutsche Luft Hansa offers a deal

Deals are rare for this route

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Dec 01

Nov 30

Nov 12

Dec 02

Dec 03

Nov 09

Nov 14

Oct 15

Oct 14

Oct 20

Oct 15

Oct 15

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?

Are direct flights from Rome to Greenville always the best option?

Can flexible travel dates help on Rome to Greenville flights?

What extra costs should I check before booking Rome to Greenville flights?

Related routes

More routes from Rome

Flights to Greenville from other cities

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Typical flight time is 44h 40m

Connecting flights are dominant

Deutsche Luft Hansa offers a deal

Deals are rare for this route

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Dec 01

Nov 30

Nov 12

Dec 02

Dec 03

Nov 09

Nov 14

Oct 15

Oct 14

Oct 20

Oct 15

Oct 15

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?