Are direct flights from Rome to Greenville always the best option?

Direct flights are often the most convenient, saving time and avoiding potential connection issues. However, they are not always the cheapest option. Flights with one or more layovers can sometimes be significantly more affordable, depending on the route and airline.

Can flexible travel dates help on Rome to Greenville flights?

Yes, being flexible with your travel dates can often lead to finding more budget-friendly flights. Prices can vary significantly between different days of the week or even different weeks. Adjusting your departure or return by a few days may result in noticeable savings.

What extra costs should I check before booking Rome to Greenville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Low-cost carriers, in particular, may charge for amenities that are included with standard fares on other airlines. Understanding these fees upfront can help you budget accurately.

Flights From Rome

To Greenville

Cheap Flights from Rome to Greenville

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Greenville

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Rome to Greenville

Explore current cheapest deals departing from Rome to Greenville

2026-10-01 – 2026-10-10
ROM - Greenville
86% AI deal score
877 €
701 €
Round trip
2026-09-23 – 2026-10-22
ROM - Greenville
78% AI deal score
813 €
720 €
Round trip
2026-09-23 – 2026-10-20
ROM - Greenville
79% AI deal score
813 €
720 €
Round trip
2026-09-23 – 2026-10-13
ROM - Greenville
79% AI deal score
814 €
723 €
Round trip
2026-09-23 – 2026-10-19
ROM - Greenville
78% AI deal score
813 €
734 €
Round trip
2026-09-24 – 2026-10-22
ROM - Greenville
77% AI deal score
813 €
748 €
Round trip
2026-09-23 – 2026-10-06
ROM - Greenville
78% AI deal score
827 €
748 €
Round trip
2026-09-24 – 2026-10-20
ROM - Greenville
77% AI deal score
813 €
749 €
Round trip
2026-09-24 – 2026-10-13
ROM - Greenville
77% AI deal score
816 €
751 €
Round trip
2026-09-21 – 2026-10-20
ROM - Greenville
78% AI deal score
813 €
754 €
Round trip

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

Flights from Rome to Greenville typically range from $891–$1483, with a median price of $1294. Right now, fares for this route are below the typical level, and only 3% of recent fares have been classified as a good price. If you are looking for cheap flights from Rome to Greenville, setting up a price alert can be helpful as deals are infrequent.

The journey from Rome to Greenville is a long-haul route, covering a distance of 7839 km. This significant distance means you should expect a longer travel time and typically more complex itineraries.

A typical journey from Rome to Greenville takes about 44h 40m, including connections. Since most itineraries connect at least once, this duration accounts for the layovers involved in traveling this route.

When considering the cheapest time to fly from Rome to Greenville, April stands out with a median fare of $1029. Other favorable months include July, with median fares around $1241, and August, where the median price is $1271. Planning your trip during these months could lead to more economical travel options.

For flights from Rome to Greenville, most itineraries connect at least once, as 0% of recent fares were non-stop. When connections are necessary, the typical number of stopovers is 2, indicating that direct flights from Rome to Greenville are not available on this route.

How much is a round trip from Rome to Greenville

Regular price: €948 - €1,829

Prices are currently below the regular range.

The regular price range for flights from Rome to Greenville is typically between 948 EUR and 1829 EUR. The current lowest deal is 719 EUR with United Airlines, for travel from Dec 3-Dec 10.

now 719 €

Low 948 €

High 1,829 €

The cheapest time to fly from Rome to Greenville

The cheapest month to fly from Rome to Greenville is April, with a median price of $1029. The most expensive month is June, with a median price of $1342. Prices are generally lower from April to August.

April

Cheapest

Flights from 1,029 €

June

Most Expensive

Flights from 1,342 €

Apr

May

Jun

Jul

Aug

Direct flights from Rome to Greenville

United Airlines

Deutsche Luft Hansa

American Airlines

JetBlue Airways

Last-minute flights going from Rome to Greenville

Mon, Jul 27

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Lufthansa

1,029 €

1,194 €

One-way

Thu, Jul 30

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM

990 €

1,076 €

One-way

Sun, Aug 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

United Airlines

982 €

866 €

One-way

Tue, Aug 18

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

1,044 €

879 €

One-way

Fri, Aug 21

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

British Airways

1,033 €

815 €

One-way

Mon, Aug 24

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

1,033 €

736 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

6 nights

Aug 24 - Aug 30

1,033 € → 736 €

29%

7 nights

Sep 8 - Sep 15

981 € → 716 €

27%

6 nights

Aug 21 - Aug 27

1,033 € → 815 €

21%

3 nights

Oct 3 - Oct 6

943 € → 737 €

22%

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are below the typical level at $719.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly from Rome to Greenville, with a median price of $1029.

⏱️ Flight duration

Typically 44h 40m with 2 stopovers

Flights from Rome to Greenville typically take 44h 40m, with a median of 2 stopovers.

✈️ Airlines & availability

Connecting flights only

There are no direct flights from Rome to Greenville; all routes require connecting flights.

🏆 Airline highlight

United Airlines offers deals

United Airlines has offered 6 deals for flights from Rome to Greenville recently.

🎯 Booking tip

Deals are rare

Deals for flights from Rome to Greenville are rare, so book when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport for a convenient and potentially cheaper option to Greenville.

📍 ~20 km from Rome city center (reachable by car or train)

💸 Flights from ~$761

Ciampino–G. B. Pastine International (CIA)

Consider Ciampino–G. B. Pastine International for your journey from Rome to Greenville.

📍 ~15 km from Rome city center (reachable by car or bus)

💸 Flights from ~$1043

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival point for flights from Rome to Greenville.

📍 ~18 km from city center (reachable by car)

💸 Flights from ~$761

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International offers significantly more direct flight options and competitive pricing for your journey.

📍 ~160 km from Greenville (reachable by car)

💸 Flights from ~$673

Business & First Class Flight Deals to Greenville

Discover luxury on the budget with premium cabin class on flights from Rome to Greenville.

Elite

Best Elite deals to Greenville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Jul 13

Greenville, United States

78% AI deal score

$5,560

$5,064

Save $496

From FCO

Elite

Jul 08

Greenville, United States

76% AI deal score

$5,334

$5,203

Save $131

From FCO

Elite

Jul 08

Greenville, United States

75% AI deal score

$5,203

From FCO

Elite

Jul 08

Greenville, United States

75% AI deal score

$5,230

$5,203

Save $27

From FCO

Elite

Jul 08

Greenville, United States

75% AI deal score

$5,226

$5,203

Save $23

From FCO

Elite

Jul 07

Greenville, United States

75% AI deal score

$5,333

From FCO

Elite

Jul 10

Greenville, United States

75% AI deal score

$5,579

$5,564

Save $15

From FCO

Elite

Jul 09

Greenville, United States

75% AI deal score

$2,635

From FCO

Elite

Jul 09

Greenville, United States

75% AI deal score

$2,659

From FCO

Elite

Sep 25

Greenville, United States

75% AI deal score

$2,661

From FCO

Elite

Sep 25

Greenville, United States

75% AI deal score

$2,661

From FCO

Elite

Sep 22

Greenville, United States

75% AI deal score

$2,661

Frequently Asked Questions About Flights to Greenville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can often reveal better deals. Looking into flights with layovers instead of direct routes may also present cheaper options.

Booking flights in advance, often several months out, can sometimes lead to lower prices. However, prices can fluctuate, so monitoring fares over time may help you identify a good booking window. Weekday bookings might also offer different pricing compared to weekend bookings.

Comparing nearby airports at both your origin and destination can sometimes uncover more economical flight options. While it may add to your ground travel time, the potential savings on airfare can be significant. Always factor in the cost and convenience of transportation to and from alternative airports.

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

Regular price: €948 - €1,829

Prices are currently below the regular range.

The regular price range for flights from Rome to Greenville is typically between 948 EUR and 1829 EUR. The current lowest deal is 719 EUR with United Airlines, for travel from Dec 3-Dec 10.

now 719 €

Low 948 €

High 1,829 €

The cheapest time to fly from Rome to Greenville

April

Cheapest

Flights from 1,029 €

June

Most Expensive

Flights from 1,342 €

Apr

May

Jun

Jul

Aug

Direct flights from Rome to Greenville

United Airlines

Deutsche Luft Hansa

American Airlines

JetBlue Airways

Last-minute flights going from Rome to Greenville

Mon, Jul 27

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Lufthansa

1,029 €

1,194 €

One-way

Thu, Jul 30

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM

990 €

1,076 €

One-way

Sun, Aug 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

United Airlines

982 €

866 €

One-way

Tue, Aug 18

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

1,044 €

879 €

One-way

Fri, Aug 21

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

British Airways

1,033 €

815 €

One-way

Mon, Aug 24

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Deutsche Luft Hansa

1,033 €

736 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

6 nights

Aug 24 - Aug 30

1,033 € → 736 €

29%

7 nights

Sep 8 - Sep 15

981 € → 716 €

27%

6 nights

Aug 21 - Aug 27

1,033 € → 815 €

21%

3 nights

Oct 3 - Oct 6

943 € → 737 €

22%

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are below the typical level at $719.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly from Rome to Greenville, with a median price of $1029.

⏱️ Flight duration

Typically 44h 40m with 2 stopovers

Flights from Rome to Greenville typically take 44h 40m, with a median of 2 stopovers.

✈️ Airlines & availability

Connecting flights only

There are no direct flights from Rome to Greenville; all routes require connecting flights.

🏆 Airline highlight

United Airlines offers deals

United Airlines has offered 6 deals for flights from Rome to Greenville recently.

🎯 Booking tip

Deals are rare

Deals for flights from Rome to Greenville are rare, so book when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport for a convenient and potentially cheaper option to Greenville.

📍 ~20 km from Rome city center (reachable by car or train)

💸 Flights from ~$761

Ciampino–G. B. Pastine International (CIA)

Consider Ciampino–G. B. Pastine International for your journey from Rome to Greenville.

📍 ~15 km from Rome city center (reachable by car or bus)

💸 Flights from ~$1043

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival point for flights from Rome to Greenville.

📍 ~18 km from city center (reachable by car)

💸 Flights from ~$761

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International offers significantly more direct flight options and competitive pricing for your journey.

📍 ~160 km from Greenville (reachable by car)

💸 Flights from ~$673

Business & First Class Flight Deals to Greenville

Discover luxury on the budget with premium cabin class on flights from Rome to Greenville.

Elite

Best Elite deals to Greenville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Jul 13

Greenville, United States

78% AI deal score

$5,560

$5,064

Save $496

From FCO

Elite

Jul 08

Greenville, United States

76% AI deal score

$5,334

$5,203

Save $131

From FCO

Elite

Jul 08

Greenville, United States

75% AI deal score

$5,203

From FCO

Elite

Jul 08

Greenville, United States

75% AI deal score

$5,230

$5,203

Save $27

From FCO

Elite

Jul 08

Greenville, United States

75% AI deal score

$5,226

$5,203

Save $23

From FCO

Elite

Jul 07

Greenville, United States

75% AI deal score

$5,333

From FCO

Elite

Jul 10

Greenville, United States

75% AI deal score

$5,579

$5,564

Save $15

From FCO

Elite

Jul 09

Greenville, United States

75% AI deal score

$2,635

From FCO

Elite

Jul 09

Greenville, United States

75% AI deal score

$2,659

From FCO

Elite

Sep 25

Greenville, United States

75% AI deal score

$2,661

From FCO

Elite

Sep 25

Greenville, United States

75% AI deal score

$2,661

From FCO

Elite

Sep 22

Greenville, United States

75% AI deal score

$2,661

Frequently Asked Questions About Flights to Greenville

Cheap Flights from Rome to Greenville

Today’s best flight deals from Rome to Greenville

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Typically 44h 40m with 2 stopovers

Connecting flights only

United Airlines offers deals

Deals are rare

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Jul 13

Jul 08

Jul 08

Jul 08

Jul 08

Jul 07

Jul 10

Jul 09

Jul 09

Sep 25

Sep 25

Sep 22

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?

Are direct flights from Rome to Greenville always the best option?

Can flexible travel dates help on Rome to Greenville flights?

What extra costs should I check before booking Rome to Greenville flights?

Related routes

More routes from Rome

Flights to Greenville from other cities

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Typically 44h 40m with 2 stopovers

Connecting flights only

United Airlines offers deals

Deals are rare

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Jul 13

Jul 08

Jul 08

Jul 08

Jul 08

Jul 07

Jul 10

Jul 09

Jul 09

Sep 25

Sep 25

Sep 22

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?