Are direct flights from Rome to Greenville always the best option?

Direct flights are often convenient and save travel time, but they are not always the most economical choice. Flights with one or more layovers can sometimes be significantly cheaper. Consider your priorities for cost versus convenience when making your decision.

Can flexible travel dates help on Rome to Greenville flights?

Absolutely, being flexible with your travel dates can often lead to finding more affordable flights. Prices can vary significantly depending on the day of the week or season. Shifting your travel by a few days may unlock better deals.

What extra costs should I check before booking Rome to Greenville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Being aware of these additional fees can help you budget accurately.

Flights From Rome

To Greenville

Cheap Flights from Rome to Greenville

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Greenville

Prices updated 2 days ago

457 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 7, 2026.)

Today’s best flight deals from Rome to Greenville

Explore current cheapest deals departing from Rome to Greenville

2026-11-17 – 2026-12-07
ROM - Greenville
87% AI deal score
830 €
625 €
Round trip
2026-12-01 – 2026-12-07
ROM - Greenville
90% AI deal score
998 €
631 €
Round trip
2026-11-18 – 2026-12-07
ROM - Greenville
87% AI deal score
830 €
638 €
Round trip
2026-12-02 – 2026-12-07
ROM - Greenville
91% AI deal score
1,020 €
646 €
Round trip
2026-11-19 – 2026-11-29
ROM - Greenville
90% AI deal score
838 €
650 €
Round trip
2026-12-14 – 2027-01-11
ROM - Greenville
88% AI deal score
949 €
712 €
Round trip
2026-09-17 – 2026-09-21
ROM - Greenville
90% AI deal score
1,016 €
730 €
Round trip
2026-10-02 – 2026-10-04
ROM - Greenville
89% AI deal score
948 €
730 €
Round trip
2026-10-10 – 2026-10-18
ROM - Greenville
85% AI deal score
982 €
745 €
Round trip
2026-12-22 – 2026-12-29
ROM - Greenville
89% AI deal score
1,035 €
794 €
Round trip

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

For flights from Rome to Greenville, fares typically range from $891–$1483, with a median of $1294. Right now, fares are below the typical level, and only 3% of recent fares were classified as a good price. New deals for this route are infrequent, so setting up a price alert can be beneficial.

When considering cheap flights from Rome to Greenville, the most affordable month to fly is April, with a median fare of $1029. Other relatively cheaper months include July, with a median of $1241, and August, where the median fare is $1271.

A typical journey from Rome to Greenville takes approximately 44h 40m, including connections. This is a long-haul route, covering a distance of 7839 km. Most itineraries on this route connect at least once, with the median number of stopovers for connecting flights being 2. There are currently no direct flights from Rome to Greenville.

How much is a round trip from Rome to Greenville

Regular price: €727 - €1,352

Prices for flights from Rome to Greenville are currently below the regular range.

The regular price range for this route is 727 EUR to 1352 EUR. The current lowest deal is 642 EUR with Aero Services Executive, for travel from Nov 18-Dec 7.

now 642 €

Low 727 €

High 1,352 €

The cheapest time to fly from Rome to Greenville

The cheapest month to fly from Rome to Greenville is April, with a median price of $1029. The most expensive month is June, with a median price of $1342. Generally, prices are lower from April to August.

April

Cheapest

Flights from 1,029 €

June

Most Expensive

Flights from 1,342 €

Apr

May

Jun

Jul

Aug

Direct flights from Rome to Greenville

Breeze Airways

Norse Atlantic UK

Aero Services Executive

KLM

Last-minute flights going from Rome to Greenville

Fri, Sep 4

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Brussels Airlines

1,009 €

1,039 €

One-way

Fri, Sep 11

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM

1,015 €

870 €

One-way

Mon, Sep 14

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Transavia France

967 €

970 €

One-way

Wed, Sep 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

WestJet

809 €

956 €

One-way

Wed, Sep 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

WestJet

798 €

973 €

One-way

Wed, Sep 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

WestJet

798 €

982 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

4 nights

Sep 17 - Sep 21

1,016 € → 730 €

28%

7 nights

Dec 22 - Dec 29

1,035 € → 794 €

23%

8 nights

Oct 10 - Oct 18

982 € → 745 €

24%

8 nights

Dec 21 - Dec 29

1,014 € → 795 €

22%

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are below the typical level, with a median of $1294.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly from Rome to Greenville, with a median price of $1029.

⏱️ Flight duration

Connecting flights take 44h 40m

Flights from Rome to Greenville typically involve 2 stopovers, with a median duration of 44h 40m.

✈️ Airlines & availability

Connecting flights only

No direct flights are available on this route; all flights include at least one stopover.

🏆 Airline highlight

Aero Services Executive has a recent deal for $642

Aero Services Executive offered a recent deal for $642 from Rome to Greenville.

🎯 Booking tip

Deals are rare

Deals on flights from Rome to Greenville are rare, so book when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient departure point for flights from Rome to Greenville.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€639

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival option for flights from Rome to Greenville.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~€639

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International is a major international hub with extensive direct flight options, a good alternative for Greenville.

📍 ~150 km from Greenville (reachable by car, but expect heavy traffic).

💸 Flights from ~€635

Business & First Class Flight Deals to Greenville

Discover luxury on the budget with premium cabin class on flights from Rome to Greenville.

Elite

Best Elite deals to Greenville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Nov 19

Greenville, United States

81% AI deal score

$2,559

$2,146

Save $413

United Airlines

Business Class

From FCO

Elite

Dec 07

Greenville, United States

75% AI deal score

$2,882

Iberia Airlines, +1

Business Class

From FCO

Elite

Oct 13

Greenville, United States

74% AI deal score

$2,831

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 24

Greenville, United States

74% AI deal score

$2,870

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 11

Greenville, United States

74% AI deal score

$3,024

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Greenville, United States

74% AI deal score

$3,026

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 15

Greenville, United States

74% AI deal score

$3,035

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 14

Greenville, United States

74% AI deal score

$3,061

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 24

Greenville, United States

74% AI deal score

$3,065

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 04

Greenville, United States

73% AI deal score

$3,115

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 23

Greenville, United States

73% AI deal score

$3,151

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Greenville, United States

73% AI deal score

$3,152

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Greenville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices from various airlines and online travel agencies can often reveal better deals. Also, looking into flights with layovers instead of direct routes may sometimes offer savings.

Booking flights in advance, often several months out, can sometimes result in lower prices. However, prices can fluctuate, so monitoring fares over time may help you identify a good booking window. Mid-week bookings might also occasionally offer better rates than weekend bookings.

Yes, comparing nearby airports for both your origin and destination can sometimes lead to more affordable flight options. While it may require additional ground transportation, the potential savings on airfare can be significant. Always factor in the total cost and travel time.

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

Regular price: €727 - €1,352

Prices for flights from Rome to Greenville are currently below the regular range.

The regular price range for this route is 727 EUR to 1352 EUR. The current lowest deal is 642 EUR with Aero Services Executive, for travel from Nov 18-Dec 7.

now 642 €

Low 727 €

High 1,352 €

The cheapest time to fly from Rome to Greenville

April

Cheapest

Flights from 1,029 €

June

Most Expensive

Flights from 1,342 €

Apr

May

Jun

Jul

Aug

Direct flights from Rome to Greenville

Breeze Airways

Norse Atlantic UK

Aero Services Executive

KLM

Last-minute flights going from Rome to Greenville

Fri, Sep 4

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Brussels Airlines

1,009 €

1,039 €

One-way

Fri, Sep 11

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM

1,015 €

870 €

One-way

Mon, Sep 14

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Transavia France

967 €

970 €

One-way

Wed, Sep 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

WestJet

809 €

956 €

One-way

Wed, Sep 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

WestJet

798 €

973 €

One-way

Wed, Sep 16

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

WestJet

798 €

982 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

4 nights

Sep 17 - Sep 21

1,016 € → 730 €

28%

7 nights

Dec 22 - Dec 29

1,035 € → 794 €

23%

8 nights

Oct 10 - Oct 18

982 € → 745 €

24%

8 nights

Dec 21 - Dec 29

1,014 € → 795 €

22%

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are below the typical level, with a median of $1294.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly from Rome to Greenville, with a median price of $1029.

⏱️ Flight duration

Connecting flights take 44h 40m

Flights from Rome to Greenville typically involve 2 stopovers, with a median duration of 44h 40m.

✈️ Airlines & availability

Connecting flights only

No direct flights are available on this route; all flights include at least one stopover.

🏆 Airline highlight

Aero Services Executive has a recent deal for $642

Aero Services Executive offered a recent deal for $642 from Rome to Greenville.

🎯 Booking tip

Deals are rare

Deals on flights from Rome to Greenville are rare, so book when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient departure point for flights from Rome to Greenville.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€639

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival option for flights from Rome to Greenville.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~€639

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International is a major international hub with extensive direct flight options, a good alternative for Greenville.

📍 ~150 km from Greenville (reachable by car, but expect heavy traffic).

💸 Flights from ~€635

Business & First Class Flight Deals to Greenville

Discover luxury on the budget with premium cabin class on flights from Rome to Greenville.

Elite

Best Elite deals to Greenville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Nov 19

Greenville, United States

81% AI deal score

$2,559

$2,146

Save $413

United Airlines

Business Class

From FCO

Elite

Dec 07

Greenville, United States

75% AI deal score

$2,882

Iberia Airlines, +1

Business Class

From FCO

Elite

Oct 13

Greenville, United States

74% AI deal score

$2,831

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 24

Greenville, United States

74% AI deal score

$2,870

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 11

Greenville, United States

74% AI deal score

$3,024

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Greenville, United States

74% AI deal score

$3,026

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 15

Greenville, United States

74% AI deal score

$3,035

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 14

Greenville, United States

74% AI deal score

$3,061

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 24

Greenville, United States

74% AI deal score

$3,065

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 04

Greenville, United States

73% AI deal score

$3,115

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 23

Greenville, United States

73% AI deal score

$3,151

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Greenville, United States

73% AI deal score

$3,152

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Greenville

Cheap Flights from Rome to Greenville

Today’s best flight deals from Rome to Greenville

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Connecting flights take 44h 40m

Connecting flights only

Aero Services Executive has a recent deal for $642

Deals are rare

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Nov 19

Dec 07

Oct 13

Oct 24

Oct 11

Oct 13

Oct 15

Oct 14

Oct 24

Oct 04

Oct 23

Oct 13

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?

Are direct flights from Rome to Greenville always the best option?

Can flexible travel dates help on Rome to Greenville flights?

What extra costs should I check before booking Rome to Greenville flights?

Related routes

More routes from Rome

Flights to Greenville from other cities

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Connecting flights take 44h 40m

Connecting flights only

Aero Services Executive has a recent deal for $642

Deals are rare

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Nov 19

Dec 07

Oct 13

Oct 24

Oct 11

Oct 13

Oct 15

Oct 14

Oct 24

Oct 04

Oct 23

Oct 13

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?