Are direct flights from Rome to Greenville always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers, but they are not always the most economical choice. Flights with one or more stops can sometimes be significantly cheaper. Weigh the trade-off between cost savings and travel duration to decide what suits your needs.

Can flexible travel dates help on Rome to Greenville flights?

Being flexible with your travel dates can often lead to finding more affordable flights. Prices can vary significantly depending on the day of the week or time of year. Adjusting your departure or return by a few days may unlock better deals.

What extra costs should I check before booking Rome to Greenville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Rome

To Greenville

Cheap Flights from Rome to Greenville

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Greenville

Prices updated 7 days ago

483 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)

Today’s best flight deals from Rome to Greenville

Explore current cheapest deals departing from Rome to Greenville

2026-11-06 – 2026-11-08
ROM - Greenville
93% AI deal score
1,064 €
687 €
Round trip
2026-11-18 – 2026-12-10
ROM - Greenville
73% AI deal score
847 €
883 €
Round trip
2026-11-18 – 2026-12-03
ROM - Greenville
73% AI deal score
852 €
904 €
Round trip
2026-11-24 – 2026-12-10
ROM - Greenville
73% AI deal score
850 €
935 €
Round trip
2026-12-17 – 2026-12-31
ROM - Greenville
76% AI deal score
969 €
938 €
Round trip
2026-11-24 – 2026-12-03
ROM - Greenville
73% AI deal score
873 €
956 €
Round trip
2026-11-21 – 2026-12-10
ROM - Greenville
74% AI deal score
847 €
979 €
Round trip
2026-11-11 – 2026-12-10
ROM - Greenville
73% AI deal score
845 €
983 €
Round trip
2026-12-16 – 2026-12-31
ROM - Greenville
75% AI deal score
958 €
994 €
Round trip
2026-11-21 – 2026-12-03
ROM - Greenville
74% AI deal score
859 €
1,004 €
Round trip

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

For flights from Rome to Greenville, fares typically range from $891–$1483, with a median of $1294. Right now, fares are below the typical level, and only 3% of recent fares were classified as a good price. This indicates that while current prices are lower than the median, finding a significantly discounted fare for this route is uncommon.

When considering cheap flights from Rome to Greenville, the cheapest time to fly is often in April, with a median fare of $1029. Other relatively inexpensive months include July, with a median of $1241, and August, where the median fare is $1271. These months present the best opportunities for more budget-friendly travel.

A typical journey from Rome to Greenville takes about 44h 40m, including connections. This extended duration reflects the nature of this route, as most itineraries connect at least once. Planning for a longer travel day is advisable given the typical journey time.

The route from Rome to Greenville covers a distance of 7839 kilometers. This classifies it as a long-haul flight, meaning you should expect a significant travel time due to the considerable distance between the two cities.

There are currently no direct flights from Rome to Greenville. Most itineraries connect at least once, with the median number of stopovers for connecting flights being 2. This means travelers should anticipate at least two stops on their journey from Rome to Greenville.

How much is a round trip from Rome to Greenville

Regular price: €902 - €1,345

Prices for flights from Rome to Greenville are currently below the regular range.

The regular price range for this route is typically between 902 EUR and 1345 EUR. The current lowest deal is 687 EUR with Deutsche Luft Hansa for travel from Nov 6-Nov 8.

now 687 €

Low 902 €

High 1,345 €

The cheapest time to fly from Rome to Greenville

The cheapest month to fly from Rome to Greenville is November, with a median price of $892. The most expensive month is October, with a median price of $1136. Prices are generally lower from October to November.

November

Cheapest

Flights from 892 €

October

Most Expensive

Flights from 1,136 €

Oct

Nov

Direct flights from Rome to Greenville

United Airlines

Breeze Airways

Aero Services Executive

JetBlue Airways

Last-minute flights going from Rome to Greenville

Sun, Nov 1

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Alitalia, JetBlue Airways, Allegiant Air

943 €

1,743 €

One-way

Wed, Nov 4

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM, JetBlue Airways, Breeze Airways

985 €

1,212 €

One-way

Thu, Nov 5

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Alitalia, JetBlue Airways, Breeze Airways

910 €

1,210 €

One-way

Sat, Nov 7

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM, JetBlue Airways, Breeze Airways

1,056 €

1,153 €

One-way

Sat, Nov 7

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM, JetBlue Airways, Breeze Airways

963 €

1,154 €

One-way

Sat, Nov 7

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Air France, JetBlue Airways, Breeze Airways

1,064 €

1,165 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

6 nights

Nov 18 - Nov 24

901 € → 757 €

16%

19 nights

Nov 18 - Dec 7

846 € → 741 €

12%

14 nights

Dec 17 - Dec 31

969 € → 935 €

5 nights

Apr 8 - Apr 13

888 € → 911 €

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are below the typical level, with a median price of $1294.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly, with a median price of $1029.

⏱️ Flight duration

Flights typically take 44h 40m

Flights from Rome to Greenville typically take 44h 40m, with 2 stopovers being common.

✈️ Airlines & availability

Connecting flights only

There are no direct flights available; connecting flights are dominant for this route.

🏆 Airline highlight

Deutsche Luft Hansa offers a deal at $687

Deutsche Luft Hansa has a deal for $687 from November 6-8, 2026.

🎯 Booking tip

Deals are rare

Deals on flights from Rome to Greenville are rare, so consider booking when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport, the cheapest option for flights from Rome to Greenville.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€677

Ciampino–G. B. Pastine International (CIA)

Depart from Ciampino–G. B. Pastine International for your trip from Rome to Greenville.

📍 ~14 km from Rome city center (reachable by car or train).

💸 Flights from ~€1,566

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival choice for flights from Rome.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~€760

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International offers extensive direct flight options globally, making it a strong alternative for international travel.

📍 ~150 km from Greenville (reachable by car, but expect heavy traffic on I-85).

💸 Flights from ~€670

Business & First Class Flight Deals to Greenville

Discover luxury on the budget with premium cabin class on flights from Rome to Greenville.

Elite

Best Elite deals to Greenville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Dec 02

Greenville, United States

70% AI deal score

$6,092

Icelandair, +1

Business Class

From FCO

Elite

Dec 02

Greenville, United States

70% AI deal score

$6,385

Icelandair, +1

Business Class

From FCO

Elite

Dec 06

Greenville, United States

70% AI deal score

$6,466

Icelandair, +1

Business Class

From FCO

Elite

Dec 02

Greenville, United States

70% AI deal score

$6,559

Icelandair, +1

Business Class

From FCO

Elite

Dec 05

Greenville, United States

70% AI deal score

$6,575

Icelandair, +1

Business Class

From FCO

Elite

Dec 02

Greenville, United States

70% AI deal score

$6,637

Icelandair, +1

Business Class

From FCO

Elite

Dec 02

Greenville, United States

70% AI deal score

$6,668

Icelandair, +1

Business Class

From FCO

Elite

Dec 02

Greenville, United States

70% AI deal score

$6,739

Icelandair, +1

Business Class

From FCO

Elite

Dec 02

Greenville, United States

70% AI deal score

$6,770

Icelandair, +1

Business Class

From FCO

Elite

Dec 30

Greenville, United States

70% AI deal score

$6,786

Icelandair, +1

Business Class

From FCO

Elite

Dec 30

Greenville, United States

70% AI deal score

$6,869

Icelandair, +1

Business Class

From FCO

Elite

Dec 06

Greenville, United States

69% AI deal score

$6,759

Icelandair, +1

Business Class

Frequently Asked Questions About Flights to Greenville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across various airlines and booking sites can also help you identify better deals. Setting up price alerts may notify you when fares drop for your desired route.

Booking flights in advance, often several months before your trip, may result in lower prices. However, prices can fluctuate, so it's often beneficial to monitor fare trends. Avoiding peak travel seasons can also lead to more economical options.

Comparing nearby airports for both your origin and destination can sometimes uncover more affordable flight options. While it may add to your ground travel time, the potential savings on airfare can be significant. Always factor in the total cost and convenience when considering this approach.

Related routes

More routes from Rome

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Flights to Greenville from other cities

Flights from Denver to Greenville Flights from Jacksonville to Greenville Flights from Madrid to Greenville Flights from Milan to Greenville Flights from Milwaukee to Greenville Flights from Vienna to Greenville

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

Regular price: €902 - €1,345

Prices for flights from Rome to Greenville are currently below the regular range.

The regular price range for this route is typically between 902 EUR and 1345 EUR. The current lowest deal is 687 EUR with Deutsche Luft Hansa for travel from Nov 6-Nov 8.

now 687 €

Low 902 €

High 1,345 €

The cheapest time to fly from Rome to Greenville

November

Cheapest

Flights from 892 €

October

Most Expensive

Flights from 1,136 €

Oct

Nov

Direct flights from Rome to Greenville

United Airlines

Breeze Airways

Aero Services Executive

JetBlue Airways

Last-minute flights going from Rome to Greenville

Sun, Nov 1

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Alitalia, JetBlue Airways, Allegiant Air

943 €

1,743 €

One-way

Wed, Nov 4

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM, JetBlue Airways, Breeze Airways

985 €

1,212 €

One-way

Thu, Nov 5

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Alitalia, JetBlue Airways, Breeze Airways

910 €

1,210 €

One-way

Sat, Nov 7

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM, JetBlue Airways, Breeze Airways

1,056 €

1,153 €

One-way

Sat, Nov 7

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

KLM, JetBlue Airways, Breeze Airways

963 €

1,154 €

One-way

Sat, Nov 7

⌛ Last-Minute

FCO - Greenville

Rome (FCO) - Greenville (GSP)

Air France, JetBlue Airways, Breeze Airways

1,064 €

1,165 €

One-way

Biggest price drops on these dates for flights from Rome to Greenville

6 nights

Nov 18 - Nov 24

901 € → 757 €

16%

19 nights

Nov 18 - Dec 7

846 € → 741 €

12%

14 nights

Dec 17 - Dec 31

969 € → 935 €

5 nights

Apr 8 - Apr 13

888 € → 911 €

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Greenville are below the typical level, with a median price of $1294.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly, with a median price of $1029.

⏱️ Flight duration

Flights typically take 44h 40m

Flights from Rome to Greenville typically take 44h 40m, with 2 stopovers being common.

✈️ Airlines & availability

Connecting flights only

There are no direct flights available; connecting flights are dominant for this route.

🏆 Airline highlight

Deutsche Luft Hansa offers a deal at $687

Deutsche Luft Hansa has a deal for $687 from November 6-8, 2026.

🎯 Booking tip

Deals are rare

Deals on flights from Rome to Greenville are rare, so consider booking when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport, the cheapest option for flights from Rome to Greenville.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€677

Ciampino–G. B. Pastine International (CIA)

Depart from Ciampino–G. B. Pastine International for your trip from Rome to Greenville.

📍 ~14 km from Rome city center (reachable by car or train).

💸 Flights from ~€1,566

Greenville main airports to arrive at

Greenville–Spartanburg International (GSP)

Cheapest

Greenville–Spartanburg International Airport is a convenient arrival choice for flights from Rome.

📍 ~17 km from Greenville (reachable by car)

💸 Flights from ~€760

Airports nearby Greenville used as alternative

Charlotte Douglas International (CLT)

Charlotte Douglas International offers extensive direct flight options globally, making it a strong alternative for international travel.

📍 ~150 km from Greenville (reachable by car, but expect heavy traffic on I-85).

💸 Flights from ~€670

Greenville, United States

69% AI deal score

$6,759

Icelandair, +1

Business Class

Frequently Asked Questions About Flights to Greenville

Cheap Flights from Rome to Greenville

Today’s best flight deals from Rome to Greenville

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Flights typically take 44h 40m

Connecting flights only

Deutsche Luft Hansa offers a deal at $687

Deals are rare

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Dec 02

Dec 02

Dec 06

Dec 02

Dec 05

Dec 02

Dec 02

Dec 02

Dec 02

Dec 30

Dec 30

Dec 06

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?

Are direct flights from Rome to Greenville always the best option?

Can flexible travel dates help on Rome to Greenville flights?

What extra costs should I check before booking Rome to Greenville flights?

Related routes

More routes from Rome

Flights to Greenville from other cities

Rome to Greenville: Overview

Insights for flights from Rome to Greenville

How much is a round trip from Rome to Greenville

The cheapest time to fly from Rome to Greenville

Direct flights from Rome to Greenville

Last-minute flights going from Rome to Greenville

Biggest price drops on these dates for flights from Rome to Greenville

Popular Airports to fly from Rome to Greenville

Rome - Greenville route insights

Recent fares are below the typical level

April is historically cheapest

Flights typically take 44h 40m

Connecting flights only

Deutsche Luft Hansa offers a deal at $687

Deals are rare

Rome main airports to depart from

Greenville main airports to arrive at

Airports nearby Greenville used as alternative

Business & First Class Flight Deals to Greenville

Best Elite deals to Greenville

Dec 02

Dec 02

Dec 06

Dec 02

Dec 05

Dec 02

Dec 02

Dec 02

Dec 02

Dec 30

Dec 30

Dec 06

Frequently Asked Questions About Flights to Greenville

How can I find cheap flights from Rome to Greenville?

When should I book flights from Rome to Greenville?

Should I compare nearby airports for flights from Rome to Greenville?