Are direct flights from Des Moines to San Antonio always the best option?

Direct flights are often more convenient and reduce travel time, but they are not always the cheapest option. Flights with one or more layovers can sometimes be significantly more affordable. Consider your priorities for cost versus convenience when choosing.

Can flexible travel dates help on Des Moines to San Antonio flights?

Yes, being flexible with your travel dates can often lead to finding cheaper flights. Prices can vary significantly depending on the day of the week or specific dates. Adjusting your departure or return by a day or two may result in notable savings.

What extra costs should I check before booking Des Moines to San Antonio flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Des Moines

To San Antonio

Cheap Flights from Des Moines to San Antonio

Browse current best options from Des Moines. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Des Moines

RatePunk searches hundreds of travel sites at once for deals on flights to San Antonio

Prices updated today

462 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 15, 2026.)

Today’s best flight deals from Des Moines to San Antonio

Explore current cheapest deals departing from Des Moines to San Antonio

2026-11-09 – 2026-12-03
DSM - San Antonio
49% AI deal score
$291
$262
Round trip
2026-11-02 – 2026-11-12
DSM - San Antonio
48% AI deal score
$304
$275
Round trip
2026-11-02 – 2026-11-05
DSM - San Antonio
67% AI deal score
$346
$279
Round trip
2026-10-30 – 2026-11-05
DSM - San Antonio
72% AI deal score
$356
$279
Round trip
2026-10-26 – 2026-11-03
DSM - San Antonio
66% AI deal score
$341
$285
Round trip
2026-11-13 – 2026-12-03
DSM - San Antonio
45% AI deal score
$294
$286
Round trip
2026-10-30 – 2026-11-12
DSM - San Antonio
48% AI deal score
$318
$291
Round trip
2026-10-05 – 2026-10-22
DSM - San Antonio
46% AI deal score
$308
$293
Round trip
2026-11-16 – 2026-12-03
DSM - San Antonio
44% AI deal score
$298
$299
Round trip
2026-11-09 – 2026-12-06
DSM - San Antonio
44% AI deal score
$291
$299
Round trip

Des Moines to San Antonio: Overview

Insights for flights from Des Moines to San Antonio

Fares for cheap flights from Des Moines to San Antonio typically range from $343 to $415, with a median price of $397. Right now, current fares are near the typical level, and about 2% of recent fares were classified as a good price. New deals appear almost daily, offering frequent opportunities to find competitive prices.

When considering the cheapest time to fly from Des Moines to San Antonio, October stands out with a median fare of $343. April also offers more affordable options, with a median fare of $363. Travelers can also find competitive prices in November, where the median fare is $397.

Most itineraries for this route connect at least once, with 0% of recent fares being non-stop. For connecting flights, the typical number of stopovers is 2. This means you should expect to make at least two stops on your journey.

A typical journey from Des Moines to San Antonio takes about 5h 3m, including connections. This duration accounts for the layovers and transfers often involved in itineraries for this route. The overall travel time reflects the need for connecting flights.

The distance between Des Moines and San Antonio is approximately 1403 kilometers. This classifies the route as a short-haul journey, meaning it is a relatively short flight that typically involves travel within the same region or to nearby regions.

How much is a round trip from Des Moines to San Antonio

Regular price: $254 - $577

Prices are currently within the regular range.

The regular price range for flights from Des Moines to San Antonio is $254-$577. The current lowest deal is $270 with Frontier Airlines for travel from Nov 9-Dec 3.

now $270

Low $254

High $577

The cheapest time to fly from Des Moines to San Antonio

The cheapest month to fly from DSM to SAT is May, with a median price of $288. The most expensive month is July, with a median price of $458. Prices are generally lower from May to December.

May

Cheapest

Flights from $288

July

Most Expensive

Flights from $458

Jan

May

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to San Antonio

Frontier Airlines

United Airlines

Allegiant Air

Southwest Airlines

Last-minute flights going from Des Moines to San Antonio

Sun, Sep 20

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$512

$914

One-way

Mon, Sep 21

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$396

$1,210

One-way

Tue, Sep 22

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$406

$702

One-way

Thu, Sep 24

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$375

$702

One-way

Fri, Sep 25

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Frontier Airlines

$417

$403

One-way

Fri, Sep 25

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Allegiant Air

$414

$474

One-way

Biggest price drops on these dates for flights from Des Moines to San Antonio

7 nights

Oct 17 - Oct 24

$359 → $268

25%

3 nights

Oct 19 - Oct 22

$375 → $302

19%

3 nights

Oct 27 - Oct 30

$374 → $305

18%

5 nights

Dec 16 - Dec 21

$365 → $305

17%

Popular Airports to fly from Des Moines to San Antonio

Des Moines - San Antonio route insights

💸 Price insights

Recent fares near the typical level

Recent fares from Des Moines to San Antonio are near the typical level of $397.

📅 Best time to fly

October offers the lowest median price

Historically, October is the cheapest month to fly, with a median price of $343.

⏱️ Flight duration

Typically 5h 3m with connecting flights

The typical flight duration from Des Moines to San Antonio with connecting flights is 5h 3m.

✈️ Airlines & availability

Connecting flights are dominant

There are no direct flights available; connecting flights are the only option for this route.

🏆 Airline highlight

Frontier Airlines has frequent deals

Frontier Airlines has 45 deals, making it a frequent option for this route.

🎯 Booking tip

Deals are frequent for this route

Deals for flights from Des Moines to San Antonio are frequent, appearing every 30 days.

Des Moines main airports to depart from

Des Moines International (DSM)

Cheapest

Des Moines International Airport offers flights to San Antonio, providing a convenient departure point.

📍 ~8 km from Des Moines (reachable by car)

💸 Flights from ~$273

San Antonio main airports to arrive at

San Antonio International (SAT)

Cheapest

San Antonio International Airport is a convenient arrival choice for flights from Des Moines to San Antonio.

📍 ~12 km from San Antonio city center (reachable by car)

💸 Flights from ~$273

Airports nearby San Antonio used as alternative

Austin–Bergstrom International (AUS)

Cheapest

Austin–Bergstrom International is a major international hub with an extensive flight network, offering many flight options.

📍 ~120 km from San Antonio (reachable by car, though heavy traffic on I-35 can increase travel time).

💸 Flights from ~$110

Business & First Class Flight Deals to San Antonio

WestJet, +1

Business Class

From DSM

Elite

Dec 02

San Antonio, United States

46% AI deal score

$2,635

WestJet, +1

Business Class

From DSM

Elite

Dec 29

San Antonio, United States

46% AI deal score

$3,002

WestJet, +1

Business Class

From DSM

Elite

Dec 01

San Antonio, United States

45% AI deal score

$2,738

WestJet, +1

Business Class

From DSM

Elite

Nov 28

San Antonio, United States

45% AI deal score

$2,741

WestJet, +1

Business Class

Frequently Asked Questions About Flights to San Antonio

To find more affordable flights, consider comparing prices across different airlines and booking sites. Being flexible with your travel dates and times can often reveal better deals. Looking into flights with layovers may also present lower-cost options.

Booking flights in advance, often several weeks or months before your intended departure, can sometimes result in better prices. However, last-minute deals can occasionally appear, so it's useful to monitor price trends. Mid-week bookings may also offer more favorable rates.

Comparing nearby airports can sometimes uncover more economical flight options or different schedules. While it may add to your ground travel time, the potential savings on airfare can be significant. Always factor in the additional cost and time of transportation to and from alternative airports.

Related routes

More routes from Des Moines

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Flights to San Antonio from other cities

Flights from Detroit to San Antonio Flights from El Paso to San Antonio Flights from Hong Kong to San Antonio Flights from Houston to San Antonio Flights from Indianapolis to San Antonio Flights from Istanbul to San Antonio Flights from Kansas City to San Antonio Flights from Las Vegas to San Antonio Flights from Los Angeles to San Antonio Flights from Miami to San Antonio Flights from New Orleans to San Antonio Flights from Sioux Falls to San Antonio

Des Moines to San Antonio: Overview

Insights for flights from Des Moines to San Antonio

How much is a round trip from Des Moines to San Antonio

Regular price: $254 - $577

Prices are currently within the regular range.

The regular price range for flights from Des Moines to San Antonio is $254-$577. The current lowest deal is $270 with Frontier Airlines for travel from Nov 9-Dec 3.

now $270

Low $254

High $577

The cheapest time to fly from Des Moines to San Antonio

The cheapest month to fly from DSM to SAT is May, with a median price of $288. The most expensive month is July, with a median price of $458. Prices are generally lower from May to December.

May

Cheapest

Flights from $288

July

Most Expensive

Flights from $458

Jan

May

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to San Antonio

Frontier Airlines

United Airlines

Allegiant Air

Southwest Airlines

Last-minute flights going from Des Moines to San Antonio

Sun, Sep 20

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$512

$914

One-way

Mon, Sep 21

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$396

$1,210

One-way

Tue, Sep 22

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$406

$702

One-way

Thu, Sep 24

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$375

$702

One-way

Fri, Sep 25

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Frontier Airlines

$417

$403

One-way

Fri, Sep 25

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Allegiant Air

$414

$474

One-way

Biggest price drops on these dates for flights from Des Moines to San Antonio

7 nights

Oct 17 - Oct 24

$359 → $268

25%

3 nights

Oct 19 - Oct 22

$375 → $302

19%

3 nights

Oct 27 - Oct 30

$374 → $305

18%

5 nights

Dec 16 - Dec 21

$365 → $305

17%

Popular Airports to fly from Des Moines to San Antonio