Are direct flights from Des Moines to San Antonio always the best option?

Direct flights usually offer convenience and save time, but they are not always the cheapest option. Flights with layovers can sometimes be more affordable. Consider your budget and time constraints when deciding between direct and connecting flights.

Can flexible travel dates help on Des Moines to San Antonio flights?

Yes, being flexible with your travel dates can often lead to significant savings on flights. Prices can fluctuate based on the day of the week or time of year. Using a flexible date search tool may reveal cheaper travel days.

What extra costs should I check before booking Des Moines to San Antonio flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Being aware of these fees can help you budget accurately for your trip.

Flights From Des Moines

To San Antonio

Cheap Flights from Des Moines to San Antonio

Browse current best options from Des Moines. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Des Moines

RatePunk searches hundreds of travel sites at once for deals on flights to San Antonio

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Des Moines to San Antonio

Explore current cheapest deals departing from Des Moines to San Antonio

2026-08-21 – 2026-08-27
DSM - San Antonio
73% AI deal score
$367
$272
Round trip
2026-08-24 – 2026-08-30
DSM - San Antonio
73% AI deal score
$367
$273
Round trip
2026-09-21 – 2026-10-01
DSM - San Antonio
48% AI deal score
$307
$282
Round trip
2026-08-30 – 2026-09-29
DSM - San Antonio
47% AI deal score
$302
$288
Round trip
2026-08-31 – 2026-09-29
DSM - San Antonio
47% AI deal score
$302
$288
Round trip
2026-08-23 – 2026-08-26
DSM - San Antonio
73% AI deal score
$388
$290
Round trip
2026-09-21 – 2026-10-15
DSM - San Antonio
44% AI deal score
$291
$292
Round trip
2026-09-30 – 2026-10-15
DSM - San Antonio
45% AI deal score
$300
$297
Round trip
2026-09-20 – 2026-10-15
DSM - San Antonio
44% AI deal score
$290
$306
Round trip
2026-10-14 – 2026-10-15
DSM - San Antonio
67% AI deal score
$379
$306
Round trip

Des Moines to San Antonio: Overview

Insights for flights from Des Moines to San Antonio

Fares for flights from Des Moines to San Antonio typically range from $343 to $415, with a median price of $397. Right now, current fares are near the typical level for this route. Only 2% of recent fares were classified as a good price, indicating that finding significantly cheaper options can be challenging.

When you are looking for cheap flights from Des Moines to San Antonio, the cheapest time to fly is often October, with a median fare of $343. April also offers lower prices, with a median of $363. November presents another option, with a median fare of $397.

A typical journey from Des Moines to San Antonio takes about 5h 3m, including connections. Most itineraries on this route connect at least once, with a median of 2 stopovers when connecting. This means you should plan for a journey that includes at least one layover.

The distance between Des Moines and San Antonio is 1403 kilometers, classifying this as a short-haul route. New deals for this route appear almost daily, suggesting that frequent checks could help you find a suitable fare.

How much is a round trip from Des Moines to San Antonio

Regular price: $311 - $733

Prices from Des Moines to San Antonio are currently below the regular range.

The regular price range for flights from Des Moines to San Antonio is typically between $311 and $733. The current lowest deal is $272 with Frontier Airlines for travel from Aug 21-Aug 27.

now $272

Low $311

High $733

The cheapest time to fly from Des Moines to San Antonio

The cheapest month to fly from DSM to SAT is May, with a median price of $288. The most expensive month is July, with a median price of $458. Prices are generally lower from May to December.

May

Cheapest

Flights from $288

July

Most Expensive

Flights from $458

Jan

May

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to San Antonio

Frontier Airlines

Allegiant Air

United Airlines

American Airlines

Last-minute flights going from Des Moines to San Antonio

Mon, Aug 3

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$440

$454

One-way

Tue, Aug 4

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

American Airlines

$473

$484

One-way

Wed, Aug 5

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Frontier Airlines

$459

$431

One-way

Fri, Aug 7

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Allegiant Air

$447

$374

One-way

Fri, Aug 7

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

American Airlines

$450

$496

One-way

Sat, Aug 8

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Deutsche Luft Hansa

$440

$506

One-way

Biggest price drops on these dates for flights from Des Moines to San Antonio

3 nights

Aug 23 - Aug 26

$388 → $280

28%

6 nights

Aug 21 - Aug 27

$367 → $272

26%

6 nights

Aug 24 - Aug 30

$367 → $273

26%

1 night

Oct 14 - Oct 15

$380 → $304

20%

Popular Airports to fly from Des Moines to San Antonio

Des Moines - San Antonio route insights

💸 Price insights

Recent fares are near the typical level

Recent fares from Des Moines to San Antonio are near the typical level at $272.

📅 Best time to fly

Fly in May for the best prices

Historically, May has the cheapest median price at $288. July is typically the most expensive.

⏱️ Flight duration

Connecting flights average 5h 3m

The typical flight duration with connections from Des Moines to San Antonio is 5h 3m.

✈️ Airlines & availability

Connecting flights are typical for this route

Connecting flights are common, with a median of 2 stopovers for this route.

🏆 Airline highlight

Frontier Airlines offers frequent deals

Frontier Airlines has 30 recent direct deals, making it a frequent option for this route.

🎯 Booking tip

Deals appear frequently

Deals for flights from Des Moines to San Antonio appear frequently, typically within 30 days.

Des Moines main airports to depart from

Des Moines International (DSM)

Cheapest

Des Moines International Airport (DSM) is a convenient option for flights from Des Moines to San Antonio.

📍 ~8 km from city center (reachable by car)

💸 Flights from ~$262

San Antonio main airports to arrive at

San Antonio International (SAT)

Cheapest

San Antonio International Airport is a convenient arrival choice for flights from Des Moines to San Antonio.

📍 ~12 km from San Antonio city center (reachable by car)

💸 Flights from ~$262

Airports nearby San Antonio used as alternative

Austin–Bergstrom International (AUS)

Cheapest

Austin–Bergstrom International is a major international hub with an extensive flight network, offering many flight options.

📍 ~120 km from San Antonio (reachable by car, but heavy traffic on I-35 can increase travel time).

💸 Flights from ~$97

Business & First Class Flight Deals to San Antonio

45% AI deal score

$2,804

Frequently Asked Questions About Flights to San Antonio

Finding affordable flights often involves comparing prices from various airlines and booking sites. Consider being flexible with your travel dates, as prices can vary significantly. Setting up price alerts may also help you catch good deals as they become available.

Booking flights in advance can often lead to better prices, though the ideal booking window can vary. It's generally a good idea to monitor prices over time. Avoiding peak travel seasons may also help you find more economical options.

Comparing nearby airports can sometimes uncover more flight options or better prices. While it might add to your travel time, the potential savings could be worthwhile. Always factor in ground transportation costs and convenience when considering alternative airports.

Related routes

More routes from Des Moines

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Flights to San Antonio from other cities

Flights from Detroit to San Antonio Flights from El Paso to San Antonio Flights from Hong Kong to San Antonio Flights from Houston to San Antonio Flights from Indianapolis to San Antonio Flights from Istanbul to San Antonio Flights from Kansas City to San Antonio Flights from Las Vegas to San Antonio Flights from Los Angeles to San Antonio Flights from Miami to San Antonio Flights from New Orleans to San Antonio Flights from Sioux Falls to San Antonio

Des Moines to San Antonio: Overview

Insights for flights from Des Moines to San Antonio

How much is a round trip from Des Moines to San Antonio

Regular price: $311 - $733

Prices from Des Moines to San Antonio are currently below the regular range.

The regular price range for flights from Des Moines to San Antonio is typically between $311 and $733. The current lowest deal is $272 with Frontier Airlines for travel from Aug 21-Aug 27.

now $272

Low $311

High $733

The cheapest time to fly from Des Moines to San Antonio

The cheapest month to fly from DSM to SAT is May, with a median price of $288. The most expensive month is July, with a median price of $458. Prices are generally lower from May to December.

May

Cheapest

Flights from $288

July

Most Expensive

Flights from $458

Jan

May

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to San Antonio

Frontier Airlines

Allegiant Air

United Airlines

American Airlines

Last-minute flights going from Des Moines to San Antonio

Mon, Aug 3

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

United Airlines

$440

$454

One-way

Tue, Aug 4

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

American Airlines

$473

$484

One-way

Wed, Aug 5

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Frontier Airlines

$459

$431

One-way

Fri, Aug 7

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Allegiant Air

$447

$374

One-way

Fri, Aug 7

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

American Airlines

$450

$496

One-way

Sat, Aug 8

⌛ Last-Minute

DSM - San Antonio

Des Moines (DSM) - San Antonio (SAT)

Deutsche Luft Hansa

$440

$506

One-way

Biggest price drops on these dates for flights from Des Moines to San Antonio

3 nights

Aug 23 - Aug 26

$388 → $280

28%

6 nights

Aug 21 - Aug 27

$367 → $272

26%

6 nights

Aug 24 - Aug 30

$367 → $273

26%

1 night

Oct 14 - Oct 15

$380 → $304

20%

Popular Airports to fly from Des Moines to San Antonio