Cheap Flights from Des Moines to San Antonio
Browse current best options from Des Moines. Become a member to unlock all deals and get alerts when new deals appear.
Deals from
Des Moines
RatePunk searches hundreds of travel sites at once for deals on flights to San Antonio
Prices updated 13 days ago
406 airlines compared
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Fares are subject to change and may not be available for all dates. (Data last updated Aug 2, 2026.)
Today’s best flight deals from Des Moines to San Antonio
Explore current cheapest deals departing from Des Moines to San Antonio
2026-08-30 – 2026-09-09
DSM - San Antonio
73% AI deal score
$337
$257
Round trip
2026-08-30 – 2026-09-01
DSM - San Antonio
76% AI deal score
$402
$257
Round trip
2026-08-30 – 2026-09-23
DSM - San Antonio
67% AI deal score
$304
$258
Round trip
2026-08-30 – 2026-09-10
DSM - San Antonio
72% AI deal score
$332
$258
Round trip
2026-08-30 – 2026-09-13
DSM - San Antonio
72% AI deal score
$324
$259
Round trip
2026-08-30 – 2026-09-29
DSM - San Antonio
66% AI deal score
$304
$260
Round trip
2026-09-28 – 2026-10-04
DSM - San Antonio
71% AI deal score
$329
$263
Round trip
2026-11-06 – 2026-11-08
DSM - San Antonio
73% AI deal score
$352
$264
Round trip
2026-10-28 – 2026-10-29
DSM - San Antonio
78% AI deal score
$379
$268
Round trip
2026-10-09 – 2026-10-11
DSM - San Antonio
73% AI deal score
$377
$272
Round trip
