Cheap Flights from Des Moines to San Antonio
Browse current best options from Des Moines. Become a member to unlock all deals and get alerts when new deals appear.
Deals from
Des Moines
RatePunk searches hundreds of travel sites at once for deals on flights to San Antonio
Prices updated 7 days ago
482 airlines compared
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Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)
Today’s best flight deals from Des Moines to San Antonio
Explore current cheapest deals departing from Des Moines to San Antonio
2026-12-14 – 2027-01-07
DSM - San Antonio
44% AI deal score
$285
$287
Round trip
2026-11-16 – 2026-12-09
DSM - San Antonio
43% AI deal score
$285
$297
Round trip
2026-11-16 – 2026-12-02
DSM - San Antonio
44% AI deal score
$292
$297
Round trip
2027-02-04 – 2027-02-24
DSM - San Antonio
43% AI deal score
$281
$305
Round trip
2026-12-14 – 2026-12-24
DSM - San Antonio
45% AI deal score
$312
$312
Round trip
2027-01-21 – 2027-02-03
DSM - San Antonio
43% AI deal score
$275
$313
Round trip
2027-01-07 – 2027-02-03
DSM - San Antonio
42% AI deal score
$259
$314
Round trip
2026-11-16 – 2026-11-25
DSM - San Antonio
44% AI deal score
$317
$314
Round trip
2027-01-10 – 2027-02-03
DSM - San Antonio
43% AI deal score
$259
$317
Round trip
2027-01-11 – 2027-02-03
DSM - San Antonio
43% AI deal score
$260
$324
Round trip
