Are direct flights from Rome to Des Moines always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers. However, they are not always the most budget-friendly choice. Flights with one or more stops can often be more affordable, though they may extend your overall travel duration. Consider your priorities for cost versus convenience.

Can flexible travel dates help on Rome to Des Moines flights?

Yes, being flexible with your travel dates can often lead to finding cheaper flights. Prices for airfare can vary significantly depending on the day of the week or the season. Adjusting your departure or return by a few days may result in noticeable savings.

What extra costs should I check before booking Rome to Des Moines flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Rome

To Des Moines

Cheap Flights from Rome to Des Moines

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Des Moines

Prices updated 1 day ago

462 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 15, 2026.)

Today’s best flight deals from Rome to Des Moines

Explore current cheapest deals departing from Rome to Des Moines

2026-09-25 – 2026-09-29
ROM - Des Moines
92% AI deal score
1,060 €
699 €
Round trip
2026-11-18 – 2026-11-23
ROM - Des Moines
87% AI deal score
921 €
730 €
Round trip
2026-10-13 – 2026-10-19
ROM - Des Moines
90% AI deal score
955 €
743 €
Round trip
2026-11-05 – 2026-11-16
ROM - Des Moines
79% AI deal score
861 €
762 €
Round trip
2026-11-05 – 2026-11-09
ROM - Des Moines
86% AI deal score
945 €
769 €
Round trip
2026-11-04 – 2026-11-16
ROM - Des Moines
78% AI deal score
857 €
778 €
Round trip
2026-11-05 – 2026-11-23
ROM - Des Moines
78% AI deal score
850 €
783 €
Round trip
2026-11-04 – 2026-11-09
ROM - Des Moines
80% AI deal score
919 €
784 €
Round trip
2026-11-04 – 2026-11-23
ROM - Des Moines
77% AI deal score
846 €
799 €
Round trip
2026-10-20 – 2026-11-16
ROM - Des Moines
78% AI deal score
880 €
802 €
Round trip

Rome to Des Moines: Overview

Insights for flights from Rome to Des Moines

For cheap flights from Rome to Des Moines, fares typically range from $1075–$1944, with a median of $1150. Right now, fares are below the typical level, and about 8% of recent fares were classified as a good price. Deals are infrequent, so setting up a price alert can be beneficial.

When is the cheapest time to fly from Rome to Des Moines? The most affordable month to fly is May, with a median fare of $1015. This is followed by April, where the median fare is $1036, and June, with a median of $1124.

Most itineraries from Rome to Des Moines connect at least once. In fact, 0% of recent fares were for non-stop flights. For connecting itineraries, the typical number of stopovers is 2.

How long is the flight from Rome to Des Moines? A typical journey, including connections, takes approximately 56h 30m. This route covers a substantial distance of 8139 km, classifying it as a long-haul flight.

How much is a round trip from Rome to Des Moines

Regular price: €897 - €1,384

Prices for flights from Rome to Des Moines are currently below the regular range.

The regular price range for flights from Rome to Des Moines is typically between 897 EUR and 1384 EUR. Currently, the lowest deal found is 699 EUR with Deutsche Luft Hansa for travel from Sep 25-Sep 29.

now 699 €

Low 897 €

High 1,384 €

The cheapest time to fly from Rome to Des Moines

The cheapest month to fly from Rome to Des Moines is May, with a median price of $1015. The most expensive month is October, with a median price of $1786. Prices are generally lower from April to July.

May

Cheapest

Flights from 1,015 €

October

Most Expensive

Flights from 1,786 €

Apr

May

Jun

Jul

Aug

Oct

Direct flights from Rome to Des Moines

Allegiant Air

TAP Portugal

Aer Lingus

Aero Services Executive

Last-minute flights going from Rome to Des Moines

Fri, Sep 18

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

KLM

1,067 €

963 €

One-way

Thu, Sep 24

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

KLM

1,065 €

694 €

One-way

Thu, Sep 24

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

WestJet, Allegiant Air

878 €

843 €

One-way

Thu, Sep 24

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

WestJet, Allegiant Air

878 €

855 €

One-way

Fri, Sep 25

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

Deutsche Luft Hansa

1,059 €

698 €

One-way

Tue, Sep 29

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

United Airlines

1,006 €

1,213 €

One-way

Biggest price drops on these dates for flights from Rome to Des Moines

4 nights

Sep 24 - Sep 28

1,065 € → 694 €

35%

4 nights

Sep 25 - Sep 29

1,059 € → 698 €

34%

6 nights

Oct 13 - Oct 19

954 € → 745 €

22%

5 nights

Nov 18 - Nov 23

920 € → 736 €

20%

Popular Airports to fly from Rome to Des Moines

Rome - Des Moines route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Des Moines are below the typical level at $699.

📅 Best time to fly

Fly in May for the best prices

Historically, May offers the lowest median prices at $1015 for flights to Des Moines.

⏱️ Flight duration

Expect a long-haul flight

Flights from Rome to Des Moines typically take 56h 30m, with 2 stopovers.

✈️ Airlines & availability

Connecting flights only

There are no direct flights available; connecting flights are dominant on this route.

🏆 Airline highlight

Deutsche Luft Hansa offers a deal

Deutsche Luft Hansa recently offered a deal for $699 from Rome to Des Moines.

🎯 Booking tip

Deals are rare on this route

Deals on flights from Rome to Des Moines are historically rare, so book when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a good option for flights from Rome to Des Moines.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€640

Ciampino–G. B. Pastine International (CIA)

Ciampino–G. B. Pastine International is an alternative departure airport for your trip to Des Moines.

📍 ~14 km from Rome city center (reachable by car or train).

💸 Flights from ~€662

Des Moines main airports to arrive at

Des Moines International (DSM)

Cheapest

Des Moines International Airport is a convenient arrival choice for reaching Des Moines and surrounding areas.

📍 ~8 km from city center (reachable by car)

💸 Flights from ~€634

Airports nearby Des Moines used as alternative

Eppley Airfield (OMA)

Cheapest

Consider Eppley Airfield for its higher flight frequency and diverse cabin class options, including Business and First.

📍 ~170 km from Des Moines (approximately a 2-hour drive, requires crossing state lines into Nebraska)

💸 Flights from ~€696

Business & First Class Flight Deals to Des Moines

Discover luxury on the budget with premium cabin class on flights from Rome to Des Moines.

Elite

Best Elite deals to Des Moines

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Oct 16

Des Moines, United States

74% AI deal score

$2,886

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Des Moines, United States

74% AI deal score

$2,886

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 16

Des Moines, United States

74% AI deal score

$2,886

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Des Moines, United States

74% AI deal score

$2,886

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 16

Des Moines, United States

74% AI deal score

$2,921

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Des Moines, United States

74% AI deal score

$2,921

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 16

Des Moines, United States

74% AI deal score

$2,921

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Des Moines, United States

74% AI deal score

$2,921

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 16

Des Moines, United States

74% AI deal score

$2,964

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 13

Des Moines, United States

74% AI deal score

$2,964

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 15

Des Moines, United States

74% AI deal score

$2,974

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 15

Des Moines, United States

74% AI deal score

$2,974

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Des Moines

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can often reveal better deals. Looking into flights with layovers instead of direct routes may also present cheaper options.

Booking flights in advance, often several months before your intended departure, can sometimes lead to lower prices. However, prices can fluctuate, so monitoring fares over time may help you identify a good booking window. Mid-week bookings are also sometimes more affordable than weekend bookings.

Comparing nearby airports at both your origin and destination can sometimes uncover more economical flight options. While it may require additional travel time to and from these airports, the savings on airfare can sometimes be significant. Always factor in the cost and convenience of ground transportation.

Rome to Des Moines: Overview

Insights for flights from Rome to Des Moines

Most itineraries from Rome to Des Moines connect at least once. In fact, 0% of recent fares were for non-stop flights. For connecting itineraries, the typical number of stopovers is 2.

How much is a round trip from Rome to Des Moines

Regular price: €897 - €1,384

Prices for flights from Rome to Des Moines are currently below the regular range.

now 699 €

Low 897 €

High 1,384 €

The cheapest time to fly from Rome to Des Moines

May

Cheapest

Flights from 1,015 €

October

Most Expensive

Flights from 1,786 €

Apr

May

Jun

Jul

Aug

Oct

Direct flights from Rome to Des Moines

Allegiant Air

TAP Portugal

Aer Lingus

Aero Services Executive

Last-minute flights going from Rome to Des Moines

Fri, Sep 18

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

KLM

1,067 €

963 €

One-way

Thu, Sep 24

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

KLM

1,065 €

694 €

One-way

Thu, Sep 24

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

WestJet, Allegiant Air

878 €

843 €

One-way

Thu, Sep 24

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

WestJet, Allegiant Air

878 €

855 €

One-way

Fri, Sep 25

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

Deutsche Luft Hansa

1,059 €

698 €

One-way

Tue, Sep 29

⌛ Last-Minute

FCO - Des Moines

Rome (FCO) - Des Moines (DSM)

United Airlines

1,006 €

1,213 €

One-way

Biggest price drops on these dates for flights from Rome to Des Moines

4 nights

Sep 24 - Sep 28

1,065 € → 694 €

35%

4 nights

Sep 25 - Sep 29

1,059 € → 698 €

34%

6 nights

Oct 13 - Oct 19

954 € → 745 €

22%

5 nights

Nov 18 - Nov 23

920 € → 736 €

20%

Popular Airports to fly from Rome to Des Moines

Rome - Des Moines route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Des Moines are below the typical level at $699.

📅 Best time to fly

Fly in May for the best prices

Historically, May offers the lowest median prices at $1015 for flights to Des Moines.

⏱️ Flight duration

Expect a long-haul flight

Flights from Rome to Des Moines typically take 56h 30m, with 2 stopovers.

✈️ Airlines & availability

Connecting flights only

There are no direct flights available; connecting flights are dominant on this route.

🏆 Airline highlight

Deutsche Luft Hansa offers a deal

Deutsche Luft Hansa recently offered a deal for $699 from Rome to Des Moines.

🎯 Booking tip

Deals are rare on this route

Deals on flights from Rome to Des Moines are historically rare, so book when you see a good price.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a good option for flights from Rome to Des Moines.

📍 ~24 km from Rome city center (reachable by car or train).

💸 Flights from ~€640

Ciampino–G. B. Pastine International (CIA)

Ciampino–G. B. Pastine International is an alternative departure airport for your trip to Des Moines.

📍 ~14 km from Rome city center (reachable by car or train).

💸 Flights from ~€662

Des Moines main airports to arrive at

Des Moines International (DSM)

Cheapest

Des Moines International Airport is a convenient arrival choice for reaching Des Moines and surrounding areas.

📍 ~8 km from city center (reachable by car)

💸 Flights from ~€634

Airports nearby Des Moines used as alternative

Eppley Airfield (OMA)

Cheapest

Consider Eppley Airfield for its higher flight frequency and diverse cabin class options, including Business and First.

📍 ~170 km from Des Moines (approximately a 2-hour drive, requires crossing state lines into Nebraska)

💸 Flights from ~€696

Des Moines, United States

74% AI deal score

$2,974

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Des Moines

Cheap Flights from Rome to Des Moines

Today’s best flight deals from Rome to Des Moines

Rome to Des Moines: Overview

Insights for flights from Rome to Des Moines

How much is a round trip from Rome to Des Moines

The cheapest time to fly from Rome to Des Moines

Direct flights from Rome to Des Moines

Last-minute flights going from Rome to Des Moines

Biggest price drops on these dates for flights from Rome to Des Moines

Popular Airports to fly from Rome to Des Moines

Rome - Des Moines route insights

Recent fares are below the typical level

Fly in May for the best prices

Expect a long-haul flight

Connecting flights only

Deutsche Luft Hansa offers a deal

Deals are rare on this route

Rome main airports to depart from

Des Moines main airports to arrive at

Airports nearby Des Moines used as alternative

Business & First Class Flight Deals to Des Moines

Best Elite deals to Des Moines

Oct 16

Oct 13

Oct 16

Oct 13

Oct 16

Oct 13

Oct 16

Oct 13

Oct 16

Oct 13

Oct 15

Oct 15

Frequently Asked Questions About Flights to Des Moines

How can I find cheap flights from Rome to Des Moines?

When should I book flights from Rome to Des Moines?

Should I compare nearby airports for flights from Rome to Des Moines?

Are direct flights from Rome to Des Moines always the best option?

Can flexible travel dates help on Rome to Des Moines flights?

What extra costs should I check before booking Rome to Des Moines flights?

Related routes

More routes from Rome

Flights to Des Moines from other cities

Rome to Des Moines: Overview

Insights for flights from Rome to Des Moines

How much is a round trip from Rome to Des Moines

The cheapest time to fly from Rome to Des Moines

Direct flights from Rome to Des Moines

Last-minute flights going from Rome to Des Moines

Biggest price drops on these dates for flights from Rome to Des Moines

Popular Airports to fly from Rome to Des Moines

Rome - Des Moines route insights

Recent fares are below the typical level

Fly in May for the best prices

Expect a long-haul flight

Connecting flights only

Deutsche Luft Hansa offers a deal

Deals are rare on this route

Rome main airports to depart from

Des Moines main airports to arrive at

Airports nearby Des Moines used as alternative

Business & First Class Flight Deals to Des Moines

Best Elite deals to Des Moines

Oct 16

Oct 13

Oct 16

Oct 13

Oct 16

Oct 13

Oct 16

Oct 13

Oct 16

Oct 13

Oct 15

Oct 15

Frequently Asked Questions About Flights to Des Moines

How can I find cheap flights from Rome to Des Moines?

When should I book flights from Rome to Des Moines?

Should I compare nearby airports for flights from Rome to Des Moines?