Are direct flights from Knoxville to Madrid always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers. However, they are not always the most budget-friendly choice. Flights with connections can sometimes be more affordable, especially if you are willing to accept a longer journey.

Can flexible travel dates help on Knoxville to Madrid flights?

Yes, being flexible with your travel dates can often lead to finding cheaper flights. Prices for airfare can vary significantly depending on the day of the week or season. Adjusting your departure or return by a few days may unlock better deals.

What extra costs should I check before booking Knoxville to Madrid flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. These additional expenses can impact the overall cost of your trip.

Flights From Knoxville

To Madrid

Cheap Flights from Knoxville to Madrid

Browse current best options from Knoxville. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Knoxville

RatePunk searches hundreds of travel sites at once for deals on flights to Madrid

Prices updated 2 days ago

458 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 7, 2026.)

Today’s best flight deals from Knoxville to Madrid

Explore current cheapest deals departing from Knoxville to Madrid

2026-10-13 – 2026-10-20
TYS - Madrid
77% AI deal score
$681
$719
Round trip
2026-12-01 – 2026-12-09
TYS - Madrid
76% AI deal score
$664
$719
Round trip
2026-12-01 – 2026-12-11
TYS - Madrid
76% AI deal score
$660
$719
Round trip
2026-09-30 – 2026-10-07
TYS - Madrid
79% AI deal score
$777
$719
Round trip
2026-10-05 – 2026-10-21
TYS - Madrid
76% AI deal score
$645
$722
Round trip
2026-11-04 – 2026-11-11
TYS - Madrid
77% AI deal score
$706
$731
Round trip
2026-11-17 – 2026-11-24
TYS - Madrid
77% AI deal score
$706
$731
Round trip
2026-11-17 – 2026-11-25
TYS - Madrid
77% AI deal score
$693
$731
Round trip
2026-09-28 – 2026-10-14
TYS - Madrid
77% AI deal score
$729
$731
Round trip
2026-09-28 – 2026-10-07
TYS - Madrid
78% AI deal score
$750
$731
Round trip

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

Flights from Knoxville to Madrid typically range from $645–$856, with a median price of $749. Right now, fares are near the typical level for this route. Currently, 0% of recent fares are classified as a good price, indicating that finding exceptionally low fares might require some flexibility.

If you are looking for cheap flights from Knoxville to Madrid, the data indicates that February is typically the most affordable month to fly, with a median fare of $351. Other cost-effective options include August, with a median fare of $574, and July, where the median fare is $581. Planning your trip during these months could lead to significant savings.

A typical journey from Knoxville to Madrid takes approximately 20h 0m, including connections. This is because most itineraries connect at least once, with the median number of stopovers for connecting flights being 2. There are currently no direct flights from Knoxville to Madrid, so all travelers should anticipate at least one stop.

The route from Knoxville to Madrid covers a distance of 6800 km, classifying it as a long-haul journey. This substantial distance means that flights will involve a considerable amount of travel time. New deals for this route appear almost daily, suggesting frequent opportunities to find suitable fares.

How much is a round trip from Knoxville to Madrid

Regular price: $555 - $1,493

Prices for flights from Knoxville to Madrid are currently within the regular range.

The regular price range for this route is between $555 and $1493. The current lowest deal is $720 with United Airlines for travel from Dec 1-Dec 9.

now $720

Low $555

High $1,493

The cheapest time to fly from Knoxville to Madrid

The cheapest month to fly from TYS to MAD is February, with a median price of $351. The most expensive month is September, with a median price of $795. Prices are generally lower from January to August.

February

Cheapest

Flights from $351

September

Most Expensive

Flights from $795

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Knoxville to Madrid

United Airlines

Allegiant Air

Iberia Airlines

KLM

Last-minute flights going from Knoxville to Madrid

Wed, Sep 2

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

Lufthansa

$788

$1,043

One-way

Tue, Sep 8

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$838

$990

One-way

Sun, Sep 13

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

Allegiant Air

$893

$904

One-way

Mon, Sep 14

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$812

$1,040

One-way

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$791

$990

One-way

Wed, Sep 16

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$786

$990

One-way

Biggest price drops on these dates for flights from Knoxville to Madrid

5 nights

Mar 8 - Mar 13

$880 → $814

4 nights

Mar 10 - Mar 14

$891 → $825

10 nights

Mar 5 - Mar 15

$884 → $838

4 nights

Jan 17 - Jan 21

$799 → $759

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

💸 Price insights

Recent fares are near the typical level.

Recent fares for Knoxville to Madrid are near the typical level, with a median of $749.

📅 Best time to fly

February is historically the cheapest month to fly.

Historically, February is the cheapest month to fly from Knoxville to Madrid, with a median price of $351.

⏱️ Flight duration

Flights typically take 20h 0m.

The median flight duration from Knoxville to Madrid is 20h 0m, with typically 2 stopovers.

✈️ Airlines & availability

Connecting flights are dominant on this route.

This route is connecting-dominant, with a median of 2 stopovers when connecting.

🏆 Airline highlight

United Airlines offers frequent deals.

United Airlines has 36 direct deals, making it a frequent option for this route.

🎯 Booking tip

Deals appear frequently for this route.

Deals for flights from Knoxville to Madrid appear frequently, with many options in the next 30 days.

Knoxville main airports to depart from

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport (TYS) is a convenient departure point for flights from Knoxville to Madrid.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~$719

Madrid main airports to arrive at

Adolfo Suárez Madrid–Barajas (MAD)

Cheapest

Adolfo Suárez Madrid–Barajas Airport is a key arrival point for flights from Knoxville to Madrid.

📍 ~14 km from Madrid city center (reachable by car, metro, and bus).

💸 Flights from ~$718

Airports nearby Madrid used as alternative

Valencia (VLC)

Valencia Airport offers excellent high-speed rail connectivity from Madrid, making it a reliable alternative for travelers.

📍 ~300 km from Madrid (reachable by high-speed train)

💸 Flights from ~$774

Business & First Class Flight Deals to Madrid

Discover luxury on the budget with premium cabin class on flights from Knoxville to Madrid.

Elite

Best Elite deals to Madrid

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From TYS

Elite

Dec 24

Madrid, Spain

92% AI deal score

$8,464

$4,646

Save $3,818

United Airlines, +1

Business Class

From TYS

Elite

Dec 24

Madrid, Spain

92% AI deal score

$8,448

$4,646

Save $3,802

United Airlines, +1

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

80% AI deal score

$8,752

$7,544

Save $1,208

Aeroméxico

Business Class

From TYS

Elite

Dec 09

Madrid, Spain

80% AI deal score

$8,809

$7,554

Save $1,255

Aer Lingus

Business Class

From TYS

Elite

Dec 29

Madrid, Spain

80% AI deal score

$8,967

$7,581

Save $1,386

Aer Lingus

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

79% AI deal score

$8,330

$7,517

Save $813

Aeroméxico

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

79% AI deal score

$8,255

$7,517

Save $738

Aeroméxico

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

79% AI deal score

$8,330

$7,517

Save $813

Aeroméxico

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

79% AI deal score

$8,330

$7,517

Save $813

Aeroméxico

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

79% AI deal score

$8,554

$7,542

Save $1,012

Aeroméxico

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

79% AI deal score

$8,297

$7,544

Save $753

Aeroméxico

Business Class

From TYS

Elite

Dec 15

Madrid, Spain

79% AI deal score

$8,330

$7,544

Save $786

Aeroméxico

Business Class

Frequently Asked Questions About Flights to Madrid

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking flights in advance, often several months out, can sometimes lead to lower prices. However, prices can fluctuate, so monitoring fares over time may help you identify an optimal booking window. Mid-week bookings are also sometimes associated with better deals.

Comparing nearby airports can sometimes provide additional flight options and potentially lower fares. While it may add to travel time, the savings could be significant. Always factor in the cost and convenience of ground transportation to and from alternative airports.

Related routes

More routes from Knoxville

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Flights to Madrid from other cities

Flights from Destin to Madrid Flights from Jerez de la Frontera to Madrid Flights from Quito to Madrid Flights from Valencia to Madrid Flights from Valledupar to Madrid Flights from Venice to Madrid Flights from Vienna to Madrid Flights from Vigo to Madrid Flights from Vilnius to Madrid Flights from Vitória, Espírito Santo to Madrid Flights from Warsaw to Madrid Flights from Washington, D.C. to Madrid

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

How much is a round trip from Knoxville to Madrid

Regular price: $555 - $1,493

Prices for flights from Knoxville to Madrid are currently within the regular range.

The regular price range for this route is between $555 and $1493. The current lowest deal is $720 with United Airlines for travel from Dec 1-Dec 9.

now $720

Low $555

High $1,493

The cheapest time to fly from Knoxville to Madrid

February

Cheapest

Flights from $351

September

Most Expensive

Flights from $795

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Knoxville to Madrid

United Airlines

Allegiant Air

Iberia Airlines

KLM

Last-minute flights going from Knoxville to Madrid

Wed, Sep 2

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

Lufthansa

$788

$1,043

One-way

Tue, Sep 8

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$838

$990

One-way

Sun, Sep 13

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

Allegiant Air

$893

$904

One-way

Mon, Sep 14

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$812

$1,040

One-way

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$791

$990

One-way

Wed, Sep 16

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$786

$990

One-way

Biggest price drops on these dates for flights from Knoxville to Madrid

5 nights

Mar 8 - Mar 13

$880 → $814

4 nights

Mar 10 - Mar 14

$891 → $825

10 nights

Mar 5 - Mar 15

$884 → $838

4 nights

Jan 17 - Jan 21

$799 → $759

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

💸 Price insights

Recent fares are near the typical level.

Recent fares for Knoxville to Madrid are near the typical level, with a median of $749.

📅 Best time to fly

February is historically the cheapest month to fly.

Historically, February is the cheapest month to fly from Knoxville to Madrid, with a median price of $351.

⏱️ Flight duration

Flights typically take 20h 0m.

The median flight duration from Knoxville to Madrid is 20h 0m, with typically 2 stopovers.

✈️ Airlines & availability

Connecting flights are dominant on this route.

This route is connecting-dominant, with a median of 2 stopovers when connecting.

🏆 Airline highlight

United Airlines offers frequent deals.

United Airlines has 36 direct deals, making it a frequent option for this route.

🎯 Booking tip

Deals appear frequently for this route.

Deals for flights from Knoxville to Madrid appear frequently, with many options in the next 30 days.

Knoxville main airports to depart from

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport (TYS) is a convenient departure point for flights from Knoxville to Madrid.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~$719

Madrid main airports to arrive at

Adolfo Suárez Madrid–Barajas (MAD)

Cheapest

Adolfo Suárez Madrid–Barajas Airport is a key arrival point for flights from Knoxville to Madrid.

📍 ~14 km from Madrid city center (reachable by car, metro, and bus).

💸 Flights from ~$718

Airports nearby Madrid used as alternative

Valencia (VLC)

Valencia Airport offers excellent high-speed rail connectivity from Madrid, making it a reliable alternative for travelers.

Madrid, Spain

79% AI deal score

$8,330

$7,544

Save $786

Aeroméxico

Business Class

Frequently Asked Questions About Flights to Madrid

Cheap Flights from Knoxville to Madrid

Today’s best flight deals from Knoxville to Madrid

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

How much is a round trip from Knoxville to Madrid

The cheapest time to fly from Knoxville to Madrid

Direct flights from Knoxville to Madrid

Last-minute flights going from Knoxville to Madrid

Biggest price drops on these dates for flights from Knoxville to Madrid

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

Recent fares are near the typical level.

February is historically the cheapest month to fly.

Flights typically take 20h 0m.

Connecting flights are dominant on this route.

United Airlines offers frequent deals.

Deals appear frequently for this route.

Knoxville main airports to depart from

Madrid main airports to arrive at

Airports nearby Madrid used as alternative

Business & First Class Flight Deals to Madrid

Best Elite deals to Madrid

Dec 24

Dec 24

Dec 15

Dec 09

Dec 29

Dec 15

Dec 15

Dec 15

Dec 15

Dec 15

Dec 15

Dec 15

Frequently Asked Questions About Flights to Madrid

How can I find cheap flights from Knoxville to Madrid?

When should I book flights from Knoxville to Madrid?

Should I compare nearby airports for flights from Knoxville to Madrid?

Are direct flights from Knoxville to Madrid always the best option?

Can flexible travel dates help on Knoxville to Madrid flights?

What extra costs should I check before booking Knoxville to Madrid flights?

Related routes

More routes from Knoxville

Flights to Madrid from other cities

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

How much is a round trip from Knoxville to Madrid

The cheapest time to fly from Knoxville to Madrid

Direct flights from Knoxville to Madrid

Last-minute flights going from Knoxville to Madrid

Biggest price drops on these dates for flights from Knoxville to Madrid

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

Recent fares are near the typical level.

February is historically the cheapest month to fly.

Flights typically take 20h 0m.

Connecting flights are dominant on this route.

United Airlines offers frequent deals.

Deals appear frequently for this route.

Knoxville main airports to depart from

Madrid main airports to arrive at

Airports nearby Madrid used as alternative

Business & First Class Flight Deals to Madrid

Best Elite deals to Madrid

Dec 24

Dec 24

Dec 15

Dec 09

Dec 29

Dec 15

Dec 15

Dec 15

Dec 15

Dec 15

Dec 15

Dec 15

Frequently Asked Questions About Flights to Madrid

How can I find cheap flights from Knoxville to Madrid?

When should I book flights from Knoxville to Madrid?

Should I compare nearby airports for flights from Knoxville to Madrid?