Are direct flights from Knoxville to Madrid always the best option?

Direct flights usually offer convenience by reducing travel time and avoiding layovers. However, they are not always the most budget-friendly option. Flights with connections can sometimes be significantly cheaper, depending on the route and timing.

Can flexible travel dates help on Knoxville to Madrid flights?

Yes, being flexible with your travel dates can often lead to finding more affordable flights. Prices can vary significantly between different days of the week or even within the same month. Adjusting your departure or return by a few days may result in savings.

What extra costs should I check before booking Knoxville to Madrid flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes or for certain payment methods. Understanding these can help you calculate the true total cost.

Flights From Knoxville

To Madrid

Cheap Flights from Knoxville to Madrid

Browse current best options from Knoxville. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Knoxville

RatePunk searches hundreds of travel sites at once for deals on flights to Madrid

Prices updated 2 days ago

461 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 14, 2026.)

Today’s best flight deals from Knoxville to Madrid

Explore current cheapest deals departing from Knoxville to Madrid

2026-10-13 – 2026-10-22
TYS - Madrid
77% AI deal score
$661
$699
Round trip
2026-11-10 – 2026-11-17
TYS - Madrid
77% AI deal score
$703
$702
Round trip
2026-11-15 – 2026-11-24
TYS - Madrid
77% AI deal score
$692
$702
Round trip
2026-11-11 – 2026-11-24
TYS - Madrid
77% AI deal score
$683
$702
Round trip
2026-12-01 – 2026-12-08
TYS - Madrid
77% AI deal score
$665
$702
Round trip
2026-12-01 – 2026-12-14
TYS - Madrid
76% AI deal score
$638
$702
Round trip
2026-10-25 – 2026-11-07
TYS - Madrid
76% AI deal score
$651
$702
Round trip
2026-10-28 – 2026-11-13
TYS - Madrid
76% AI deal score
$644
$702
Round trip
2026-10-06 – 2026-10-15
TYS - Madrid
77% AI deal score
$664
$702
Round trip
2027-02-16 – 2027-02-24
TYS - Madrid
77% AI deal score
$702
$707
Round trip

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

Flights from Knoxville to Madrid typically range from $645–$856, with a median price of $749. Right now, fares are near the typical level for this route. Currently, 0% of recent fares are classified as a good price, indicating that finding exceptionally low fares might require some flexibility.

If you are looking for cheap flights from Knoxville to Madrid, the data indicates that February is typically the most affordable month to fly, with a median fare of $351. Other cost-effective options include August, with a median fare of $574, and July, where the median fare is $581. Planning your trip during these months could lead to significant savings.

A typical journey from Knoxville to Madrid takes approximately 20h 0m, including connections. This is because most itineraries connect at least once, with the median number of stopovers for connecting flights being 2. There are currently no direct flights from Knoxville to Madrid, so all travelers should anticipate at least one stop.

The route from Knoxville to Madrid covers a distance of 6800 km, classifying it as a long-haul journey. This substantial distance means that flights will involve a considerable amount of travel time. New deals for this route appear almost daily, suggesting frequent opportunities to find suitable fares.

How much is a round trip from Knoxville to Madrid

Regular price: $627 - $1,411

Prices for flights from Knoxville to Madrid are currently within the regular range.

The regular price range for flights from Knoxville to Madrid is between $627 and $1411. The current lowest deal is $653 with Deutsche Luft Hansa for travel from Jan 10-Jan 17.

now $653

Low $627

High $1,411

The cheapest time to fly from Knoxville to Madrid

The cheapest month to fly from TYS to MAD is February, with a median price of $351. The most expensive month is September, with a median price of $795. Prices are generally lower from January to August.

February

Cheapest

Flights from $351

September

Most Expensive

Flights from $795

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Knoxville to Madrid

United Airlines

Allegiant Air

Iberia Airlines

KLM

Last-minute flights going from Knoxville to Madrid

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$830

$976

One-way

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$875

$990

One-way

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

KLM

$875

$1,009

One-way

Tue, Sep 22

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$762

$815

One-way

Wed, Sep 23

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$827

$816

One-way

Sat, Sep 26

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$825

$702

One-way

Biggest price drops on these dates for flights from Knoxville to Madrid

7 nights

Sep 27 - Oct 4

$819 → $711

13%

7 nights

Jan 10 - Jan 17

$760 → $653

14%

6 nights

Sep 28 - Oct 4

$812 → $711

12%

7 nights

Sep 28 - Oct 5

$812 → $711

12%

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

💸 Price insights

Recent fares are near the typical level

Recent fares from Knoxville to Madrid are near the typical level of $749.

📅 Best time to fly

Fly in February for the best prices

Historically, February is the cheapest month to fly, with a median price of $351.

⏱️ Flight duration

Connecting flights take 20h 0m

Flights from Knoxville to Madrid typically take 20h 0m, with 2 stopovers.

✈️ Airlines & availability

Deals are frequent for this route

Deals for flights from Knoxville to Madrid are frequent, appearing multiple times a week.

🏆 Airline highlight

Deutsche Luft Hansa offers a recent deal

A recent deal for $653 was found on Deutsche Luft Hansa for January 10-17.

🎯 Booking tip

Consider connecting flights for this route

This route is connecting-dominant, so consider flights with stopovers for more options.

Knoxville main airports to depart from

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport (TYS) is a convenient departure point for flights from Knoxville to Madrid.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~$719

Madrid main airports to arrive at

Adolfo Suárez Madrid–Barajas (MAD)

Cheapest

Adolfo Suárez Madrid–Barajas Airport is a key arrival point for flights from Knoxville to Madrid.

📍 ~14 km from Madrid city center (reachable by car, metro, and bus).

💸 Flights from ~$718

Airports nearby Madrid used as alternative

Valencia (VLC)

Valencia Airport offers excellent high-speed rail connectivity from Madrid, making it a reliable alternative for travelers.

📍 ~300 km from Madrid (reachable by high-speed train)

💸 Flights from ~$774

Business & First Class Flight Deals to Madrid

Discover luxury on the budget with premium cabin class on flights from Knoxville to Madrid.

Elite

Best Elite deals to Madrid

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,135

$6,377

Save $1,758

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,089

$6,377

Save $1,712

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,089

$6,382

Save $1,707

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,117

$6,386

Save $1,731

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,310

$6,386

Save $1,924

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,100

$6,386

Save $1,714

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,166

$6,386

Save $1,780

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,071

$6,386

Save $1,685

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,134

$6,386

Save $1,748

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,197

$6,386

Save $1,811

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,089

$6,386

Save $1,703

Aeroméxico

Business Class

From TYS

Elite

Oct 31

Madrid, Spain

82% AI deal score

$8,089

$6,386

Save $1,703

Aeroméxico

Business Class

Frequently Asked Questions About Flights to Madrid

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking flights in advance, often several months out, can sometimes lead to lower prices. However, prices can fluctuate, so monitoring fares over time may help you identify an optimal booking window. Mid-week bookings are also sometimes associated with better deals.

Comparing nearby airports can sometimes provide more flight options or different pricing. While it may add to your ground travel, the potential savings on airfare could make it a worthwhile consideration. Always factor in the total cost and convenience.

Related routes

More routes from Knoxville

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Flights to Madrid from other cities

Flights from Destin to Madrid Flights from Jerez de la Frontera to Madrid Flights from Quito to Madrid Flights from Valencia to Madrid Flights from Valledupar to Madrid Flights from Venice to Madrid Flights from Vienna to Madrid Flights from Vigo to Madrid Flights from Vilnius to Madrid Flights from Vitória, Espírito Santo to Madrid Flights from Warsaw to Madrid Flights from Washington, D.C. to Madrid

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

How much is a round trip from Knoxville to Madrid

Regular price: $627 - $1,411

Prices for flights from Knoxville to Madrid are currently within the regular range.

The regular price range for flights from Knoxville to Madrid is between $627 and $1411. The current lowest deal is $653 with Deutsche Luft Hansa for travel from Jan 10-Jan 17.

now $653

Low $627

High $1,411

The cheapest time to fly from Knoxville to Madrid

February

Cheapest

Flights from $351

September

Most Expensive

Flights from $795

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Knoxville to Madrid

United Airlines

Allegiant Air

Iberia Airlines

KLM

Last-minute flights going from Knoxville to Madrid

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$830

$976

One-way

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$875

$990

One-way

Tue, Sep 15

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

KLM

$875

$1,009

One-way

Tue, Sep 22

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$762

$815

One-way

Wed, Sep 23

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$827

$816

One-way

Sat, Sep 26

⌛ Last-Minute

TYS - Madrid

Knoxville (TYS) - Madrid (MAD)

United Airlines

$825

$702

One-way

Biggest price drops on these dates for flights from Knoxville to Madrid

7 nights

Sep 27 - Oct 4

$819 → $711

13%

7 nights

Jan 10 - Jan 17

$760 → $653

14%

6 nights

Sep 28 - Oct 4

$812 → $711

12%

7 nights

Sep 28 - Oct 5

$812 → $711

12%

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

💸 Price insights

Recent fares are near the typical level

Recent fares from Knoxville to Madrid are near the typical level of $749.

📅 Best time to fly

Fly in February for the best prices

Historically, February is the cheapest month to fly, with a median price of $351.

⏱️ Flight duration

Connecting flights take 20h 0m

Flights from Knoxville to Madrid typically take 20h 0m, with 2 stopovers.

✈️ Airlines & availability

Deals are frequent for this route

Deals for flights from Knoxville to Madrid are frequent, appearing multiple times a week.

🏆 Airline highlight

Deutsche Luft Hansa offers a recent deal

A recent deal for $653 was found on Deutsche Luft Hansa for January 10-17.

🎯 Booking tip

Consider connecting flights for this route

This route is connecting-dominant, so consider flights with stopovers for more options.

Knoxville main airports to depart from

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport (TYS) is a convenient departure point for flights from Knoxville to Madrid.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~$719

Madrid main airports to arrive at

Adolfo Suárez Madrid–Barajas (MAD)

Cheapest

Adolfo Suárez Madrid–Barajas Airport is a key arrival point for flights from Knoxville to Madrid.

📍 ~14 km from Madrid city center (reachable by car, metro, and bus).

💸 Flights from ~$718

Airports nearby Madrid used as alternative

Valencia (VLC)

Valencia Airport offers excellent high-speed rail connectivity from Madrid, making it a reliable alternative for travelers.

Madrid, Spain

82% AI deal score

$8,089

$6,386

Save $1,703

Aeroméxico

Business Class

Frequently Asked Questions About Flights to Madrid

Cheap Flights from Knoxville to Madrid

Today’s best flight deals from Knoxville to Madrid

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

How much is a round trip from Knoxville to Madrid

The cheapest time to fly from Knoxville to Madrid

Direct flights from Knoxville to Madrid

Last-minute flights going from Knoxville to Madrid

Biggest price drops on these dates for flights from Knoxville to Madrid

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

Recent fares are near the typical level

Fly in February for the best prices

Connecting flights take 20h 0m

Deals are frequent for this route

Deutsche Luft Hansa offers a recent deal

Consider connecting flights for this route

Knoxville main airports to depart from

Madrid main airports to arrive at

Airports nearby Madrid used as alternative

Business & First Class Flight Deals to Madrid

Best Elite deals to Madrid

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Frequently Asked Questions About Flights to Madrid

How can I find cheap flights from Knoxville to Madrid?

When should I book flights from Knoxville to Madrid?

Should I compare nearby airports for flights from Knoxville to Madrid?

Are direct flights from Knoxville to Madrid always the best option?

Can flexible travel dates help on Knoxville to Madrid flights?

What extra costs should I check before booking Knoxville to Madrid flights?

Related routes

More routes from Knoxville

Flights to Madrid from other cities

Knoxville to Madrid: Overview

Insights for flights from Knoxville to Madrid

How much is a round trip from Knoxville to Madrid

The cheapest time to fly from Knoxville to Madrid

Direct flights from Knoxville to Madrid

Last-minute flights going from Knoxville to Madrid

Biggest price drops on these dates for flights from Knoxville to Madrid

Popular Airports to fly from Knoxville to Madrid

Knoxville - Madrid route insights

Recent fares are near the typical level

Fly in February for the best prices

Connecting flights take 20h 0m

Deals are frequent for this route

Deutsche Luft Hansa offers a recent deal

Consider connecting flights for this route

Knoxville main airports to depart from

Madrid main airports to arrive at

Airports nearby Madrid used as alternative

Business & First Class Flight Deals to Madrid

Best Elite deals to Madrid

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Oct 31

Frequently Asked Questions About Flights to Madrid

How can I find cheap flights from Knoxville to Madrid?

When should I book flights from Knoxville to Madrid?

Should I compare nearby airports for flights from Knoxville to Madrid?