Are direct flights from Panama City to Madrid always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, connecting flights can sometimes be more affordable, even with the added travel duration. The 'best' option often depends on your priorities regarding cost versus convenience.

Can flexible travel dates help on Panama City to Madrid flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying during off-peak seasons or on weekdays often results in lower fares. Even shifting your departure or return by a day or two may lead to savings.

What extra costs should I check before booking Panama City to Madrid flights?

Always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Being aware of these additional expenses can help you budget accurately.

Flights From Panama City

To Madrid

Cheap Flights from Panama City to Madrid

Browse current best options from Panama City. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Panama City

RatePunk searches hundreds of travel sites at once for deals on flights to Madrid

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Panama City to Madrid

Explore current cheapest deals departing from Panama City to Madrid

2026-10-14 – 2026-10-21
ECP - Madrid
82% AI deal score
$852
$715
Round trip
2026-10-06 – 2026-10-13
ECP - Madrid
82% AI deal score
$842
$715
Round trip
2026-10-07 – 2026-10-14
ECP - Madrid
82% AI deal score
$844
$715
Round trip
2026-11-09 – 2026-11-26
ECP - Madrid
82% AI deal score
$873
$746
Round trip
2027-01-13 – 2027-01-20
ECP - Madrid
83% AI deal score
$918
$747
Round trip
2027-01-12 – 2027-01-19
ECP - Madrid
83% AI deal score
$909
$748
Round trip
2026-10-16 – 2026-10-23
ECP - Madrid
81% AI deal score
$855
$748
Round trip
2026-10-01 – 2026-10-15
ECP - Madrid
80% AI deal score
$813
$764
Round trip
2026-11-01 – 2026-11-12
ECP - Madrid
82% AI deal score
$855
$767
Round trip
2026-10-08 – 2026-10-15
ECP - Madrid
80% AI deal score
$848
$775
Round trip

Panama City to Madrid: Overview

Insights for flights from Panama City to Madrid

Most itineraries for cheap flights from Panama City to Madrid connect at least once, with 0% of recent fares being non-stop. For connecting itineraries, the median number of stopovers is 3. This means you should expect a journey with multiple stops when planning your trip.

When considering the cheapest time to fly from Panama City to Madrid, you'll find that August is typically the most affordable month, with a median fare of $345. September also offers competitive prices, with a median fare of $486. Following these, December presents a median fare of $773, making it another relatively cheaper option.

Fares from Panama City to Madrid typically range from $1089–$1745, with a median of $1303. Right now, current fares are below the typical level for this route. However, the share of recent fares classified as a good price is 0%, indicating that finding significantly discounted tickets may be challenging.

A typical journey from Panama City to Madrid takes approximately 34h 16m, including connections. Given that most itineraries involve at least one stopover, this duration reflects the time spent in transit and during layovers. This route is classified as long-haul, covering a substantial distance of 7268 km.

How much is a round trip from Panama City to Madrid

Regular price: $700 - $1,171

Prices are currently within the regular range.

The regular price range for flights from Panama City to Madrid is $700 to $1171. The current lowest deal is $710 with Air France for travel from Oct 14-Oct 21.

now $710

Low $700

High $1,171

The cheapest time to fly from Panama City to Madrid

The cheapest month to fly from ECP to MAD is August, with a median price of $345. The most expensive month is March, with a median price of $2003. Prices are generally lower from April to December.

August

Cheapest

Flights from $345

March

Most Expensive

Flights from $2,003

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Panama City to Madrid

United Airlines

KLM

Air France

Air Canada

Last-minute flights going from Panama City to Madrid

Sun, Jul 26

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

United Airlines

$1,059

$1,579

One-way

Tue, Jul 28

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

United Airlines

$1,061

$1,111

One-way

Tue, Jul 28

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

WestJet, Air Canada

$1,222

$2,867

One-way

Wed, Jul 29

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

WestJet, Air Canada

$1,213

$2,989

One-way

Thu, Jul 30

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

United Airlines

$1,061

$1,161

One-way

Sat, Aug 1

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

KLM, Iberia Airlines

$872

$1,807

One-way

Biggest price drops on these dates for flights from Panama City to Madrid

7 nights

Dec 10 - Dec 17

$1,064 → $862

19%

7 nights

Jan 13 - Jan 20

$909 → $719

21%

7 nights

Jan 12 - Jan 19

$905 → $720

20%

7 nights

Oct 14 - Oct 21

$848 → $710

16%

Popular Airports to fly from Panama City to Madrid

Panama City - Madrid route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Panama City to Madrid are below the typical level, with a median of $1303.

📅 Best time to fly

August is historically cheapest at $345

Historically, August is the cheapest month to fly from Panama City to Madrid, with a median price of $345.

⏱️ Flight duration

Connecting flights average 34h 16m

Flights from Panama City to Madrid typically involve connections, with a median flight time of 34h 16m.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant for this route, with a median of 3 stopovers in recent bookings.

🏆 Airline highlight

Air France offers a recent deal at $710

Air France recently offered a deal for $710 from Panama City to Madrid for Oct 14-Oct 21.

🎯 Booking tip

Deals are frequent on this route

Deals on flights from Panama City to Madrid are frequent, appearing often in the last 30 days.

Panama City main airports to depart from

Northwest Florida Beaches International (ECP)

Cheapest

Northwest Florida Beaches International (ECP) is a good option for flights from Panama City to Madrid.

📍 ~25 km from Panama City (reachable by car)

💸 Flights from ~$748

Madrid main airports to arrive at

Adolfo Suárez Madrid–Barajas (MAD)

Cheapest

Adolfo Suárez Madrid–Barajas Airport is a key arrival point for reaching Madrid and surrounding areas.

📍 ~12 km from Madrid city center (reachable by car, metro, bus, train).

💸 Flights from ~$744

Airports nearby Madrid used as alternative

Valencia (VLC)

Valencia Airport offers a wide range of European and domestic connections, making it a practical alternative.

📍 ~300 km from Madrid (reachable by high-speed rail)

💸 Flights from ~$930

Business & First Class Flight Deals to Madrid

75% AI deal score

$3,692

Frequently Asked Questions About Flights to Madrid

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking in advance is often recommended, especially for international routes. Prices may fluctuate, so monitoring fares over several weeks can help you identify a good booking window. Weekday bookings sometimes offer better rates than weekend bookings.

Comparing nearby airports can sometimes lead to more economical flight options. While it may add to your travel time, the potential savings on airfare can be significant. Always factor in the cost and convenience of ground transportation to and from alternative airports.

Related routes

More routes from Panama City

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Flights to Madrid from other cities

Flights from Bergerac to Madrid Flights from Edinburgh to Madrid Flights from Eindhoven to Madrid Flights from El Paso to Madrid Flights from Erie to Madrid Flights from Eugene to Madrid Flights from Faro to Madrid Flights from Fernando de Noronha to Madrid Flights from Fort-de-France to Madrid Flights from Fresno to Madrid Flights from Friedrichshafen to Madrid Flights from Karlsruhe to Madrid

Panama City to Madrid: Overview

Insights for flights from Panama City to Madrid

How much is a round trip from Panama City to Madrid

Regular price: $700 - $1,171

Prices are currently within the regular range.

The regular price range for flights from Panama City to Madrid is $700 to $1171. The current lowest deal is $710 with Air France for travel from Oct 14-Oct 21.

now $710

Low $700

High $1,171

The cheapest time to fly from Panama City to Madrid

The cheapest month to fly from ECP to MAD is August, with a median price of $345. The most expensive month is March, with a median price of $2003. Prices are generally lower from April to December.

August

Cheapest

Flights from $345

March

Most Expensive

Flights from $2,003

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Panama City to Madrid

United Airlines

KLM

Air France

Air Canada

Last-minute flights going from Panama City to Madrid

Sun, Jul 26

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

United Airlines

$1,059

$1,579

One-way

Tue, Jul 28

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

United Airlines

$1,061

$1,111

One-way

Tue, Jul 28

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

WestJet, Air Canada

$1,222

$2,867

One-way

Wed, Jul 29

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

WestJet, Air Canada

$1,213

$2,989

One-way

Thu, Jul 30

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

United Airlines

$1,061

$1,161

One-way

Sat, Aug 1

⌛ Last-Minute

ECP - Madrid

Panama City (ECP) - Madrid (MAD)

KLM, Iberia Airlines

$872

$1,807

One-way

Biggest price drops on these dates for flights from Panama City to Madrid

7 nights

Dec 10 - Dec 17

$1,064 → $862

19%

7 nights

Jan 13 - Jan 20

$909 → $719

21%

7 nights

Jan 12 - Jan 19

$905 → $720

20%

7 nights

Oct 14 - Oct 21

$848 → $710

16%

Popular Airports to fly from Panama City to Madrid