From Panama City
Cheap Flights from Panama City
Browse current best options from Panama City. Become a member to unlock all deals and get alerts when new deals appear.
Deals from
Panama City
RatePunk searches hundreds of travel sites at once for deals on flights from Panama City
Prices updated 5 days ago
402 airlines compared
80%+ AI score for best value
Fares are subject to change and may not be available for all dates. (Data last updated Jul 12, 2026.)
All Deals
⌛ Last-Minute
🔥 Trending
🌎 Long-Haul
🏖 Beach
🏙️ City Break
🌄 Nature
🎢 Family
🧘 Wellness
💖 Romantic
🏛 Culture
🎉 Party
🌍 Hidden Gems
Today’s best flight deals from Panama City
Explore current cheapest deals departing from Panama City
One-way
Sort by: Cheapest
ECP
Austin
United States • Nov 2026
$103
$77
One-way
ECP
Houston
United States • Aug 2026
$107
$80
One-way
ECP
Houston
United States • Dec 2026
$125
$81
One-way
ECP
Atlanta
United States • Sep 2026
$186
$93
One-way
ECP
New York
United States • Sep 2026
$192
$94
One-way
ECP
Nashville
United States • Sep 2026
$79
$99
One-way
ECP
Indianapolis
United States • Oct 2026
$224
$100
One-way
ECP
Washington, D.C.
United States • Sep 2026
$222
$100
One-way
ECP
Detroit
United States • Sep 2026
$205
$101
One-way
ECP
Philadelphia
United States • Aug 2026
$102
$102
One-way
Unlock all 500+ flight deals from Panama City and get alerts when great deals appear
Flights from Panama City: Overview
Insights for flights from Panama City
Most popular airlines from Panama City
Deutsche Luft Hansa
Southwest Airlines
United Airlines
American Airlines
American Eagle Airlines
PSA Airlines
Midwest Airlines
SkyWest Airlines
Last-minute flights going from Panama City soon
Wed, Jul 15
ECP - Tokyo
Panama City (ECP) - Tokyo (HND)
Deutsche Luft Hansa
$1,496
$1,428
One-way
Mon, Jul 20
ECP - Kahului
Panama City (ECP) - Kahului (OGG)
United Airlines
$899
$867
One-way
Thu, Jul 16
ECP - Lansing
Panama City (ECP) - Lansing (LAN)
American Airlines
$516
$404
One-way
Fri, Jul 17
ECP - Charlottesville
Panama City (ECP) - Charlottesville (CHO)
American Airlines
$568
$419
One-way
Sun, Jul 12
ECP - Riyadh
Panama City (ECP) - Riyadh (RUH)
Qatar Airways
$1,700
$1,792
One-way
Mon, Jul 13
ECP - Hagåtña
Panama City (ECP) - Hagåtña (GUM)
United Airlines
$2,640
$2,604
One-way
Most popular destinations to fly from Panama City
Seoul
South Korea • Sep 2026
from
$831
Dubrovnik
Croatia • Jul 2026
from
$965
Nairobi
Kenya • Sep 2026
from
$1,164
Honolulu
United States • Sep 2026
from
$493
Venice
Italy • Oct 2026
from
$760
Rome
Italy • Dec 2026
from
$774
Biggest price drops on international destinations from Panama City
ECP - Frankfurt
$1,136 → $750
ECP - Tallinn
$1,128 → $745
ECP - Seoul
$1,177 → $831
ECP - Billund
$1,185 → $883
Popular Airports from Panama City
Panama City airport insights
🎯 Booking tip
Watch fares to Houston
Flights from Panama City to Houston start at $80.
📅 Cheapest travel period
Jan, Sep
Flights from ECP tend to be cheaper in January and September.
⏱️ Best time to book
8+ months in advance
Booking 8+ months in advance from ECP is often cheaper than booking closer to departure.
✈️ Airlines to watch
Southwest Airlines, Deutsche Luft Hansa, United Airlines, American Airlines
Major US carriers and low-cost airlines offer diverse flight options from Panama City.
💸 Cheapest deals found
From ~$77 direct / ~$160 roundtrip
The cheapest flights from ECP are to destinations within the United States, including Houston and Austin.
🗓️ Best days to catch a deal
Wed - Sat - Thu
The cheapest days to fly from ECP are Wednesday, Saturday, and Thursday, with fares from $99.
Panama City main airports to depart from
Northwest Florida Beaches International (ECP)
This airport is useful for travelers seeking flights from the Panama City area.
📍 ~26 km from Panama City (reachable by car)
💸 Flights from ~$161
Airports nearby Panama City used as alternative
Destin–Fort Walton Beach (VPS)
Destin–Fort Walton Beach is a close alternative, serving the same coastal region with robust flight schedules.
📍 ~90 km from Panama City (reachable by car)
💸 Flights from ~$59
Pensacola International (PNS)
Pensacola International offers more frequent daily departures and First Class options not always available at ECP.
📍 ~151 km from Panama City (reachable by car)
💸 Flights from ~$95
Tallahassee International (TLH)
Tallahassee International provides consistent service to major hubs and different scheduling windows due to its timezone.
📍 ~128 km from Panama City (reachable by car)
💸 Flights from ~$77
Mobile Regional (MOB)
Mobile Regional provides additional options for travelers heading west, including premium cabin classes.
📍 ~255 km from Panama City (reachable by car)
💸 Flights from ~$249
Hartsfield–Jackson Atlanta International (ATL)
Hartsfield–Jackson Atlanta International is a major hub, often cheaper for international or long-haul domestic routes.
📍 ~404 km from Panama City (reachable by car)
💸 Flights from ~$45
Business & First Class Flight Deals from Panama City
Discover luxury on the budget with premium cabin class on flights from Panama City.
Elite
Best Elite deals from Panama City
Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.
From ECP
Elite
Chicago
United States • Aug 2026
92% AI deal score
$869
$519
Save $350
United Airlines
Business Class
From ECP
Elite
San Francisco
United States • Aug 2026
86% AI deal score
$1,228
$861
Save $367
Delta
Business Class
From ECP
Elite
Seattle
United States • Nov 2026
86% AI deal score
$1,387
$771
Save $616
Delta
Business Class
From ECP
Elite
San Francisco
United States • Aug 2026
86% AI deal score
$1,229
$861
Save $368
Delta
Business Class
From ECP
Elite
Seattle
United States • Nov 2026
86% AI deal score
$1,389
$771
Save $618
Delta
Business Class
From ECP
Elite
Las Vegas
United States • Oct 2026
84% AI deal score
$1,333
$969
Save $364
Delta
Business Class
From ECP
Elite
Honolulu
United States • Mar 2027
84% AI deal score
$5,109
$3,206
Save $1,903
United Airlines
Business Class
From ECP
Elite
Las Vegas
United States • Oct 2026
84% AI deal score
$1,335
$969
Save $366
Delta
Business Class
From ECP
Elite
San Diego
United States • Sep 2026
82% AI deal score
$1,084
$837
Save $247
Delta
Business Class
From ECP
Elite
San Diego
United States • Sep 2026
82% AI deal score
$1,088
$837
Save $251
Delta
Business Class
From ECP
Elite
Aruba
Aruba • Jul 2026
80% AI deal score
$1,732
$1,278
Save $454
American
Business Class
From ECP
Elite
Philadelphia
United States • Oct 2026
78% AI deal score
$819
$593
Save $226
Delta
Business Class
From ECP
Elite
Boston
United States • Oct 2026
78% AI deal score
$923
$711
Save $212
Delta
Business Class
From ECP
Elite
Fort Lauderdale
United States • Oct 2026
75% AI deal score
$677
$512
Save $165
American
Business Class
From ECP
Elite
Fort Lauderdale
United States • Oct 2026
75% AI deal score
$677
$512
Save $165
American
Business Class
From ECP
Elite
Willemstad
Curaçao • Aug 2026
75% AI deal score
$1,492
$1,298
Save $194
American
Business Class
From ECP
Elite
New Orleans
United States • Aug 2026
72% AI deal score
$724
$527
Save $197
Delta
Business Class
From ECP
Elite
New Orleans
United States • Aug 2026
72% AI deal score
$724
$527
Save $197
Delta
Business Class
From ECP
Elite
Bogotá
Colombia • Sep 2026
70% AI deal score
$1,078
$999
Save $79
United
Business Class
From ECP
Elite
Washington, D.C.
United States • Oct 2026
69% AI deal score
$622
$506
Save $116
American
Business Class
From ECP
Elite
Washington, D.C.
United States • Oct 2026
69% AI deal score
$622
$506
Save $116
American
Business Class
From ECP
Elite
New York
United States • Jan 2027
66% AI deal score
$719
$649
Save $70
Delta
Business Class
From ECP
Elite
Chicago
United States • Nov 2026
65% AI deal score
$612
$519
Save $93
United
Business Class