Are direct flights from Medellín to São Paulo always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers, which can be appealing. However, flights with one or more stops are often more budget-friendly. The 'best' option depends on your priorities regarding cost versus travel time and comfort.

Can flexible travel dates help on Medellín to São Paulo flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Mid-week flights or those during off-peak seasons often have lower fares than weekend or holiday travel. Adjusting your departure or return by even a few days may result in considerable savings.

What extra costs should I check before booking Medellín to São Paulo flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Medellín

To São Paulo

Cheap Flights from Medellín to São Paulo

Browse current best options from Medellín. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Medellín

RatePunk searches hundreds of travel sites at once for deals on flights to São Paulo

Prices updated today

485 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Nov 2, 2026.)

Today’s best flight deals from Medellín to São Paulo

Explore current cheapest deals departing from Medellín to São Paulo

2027-03-07 – 2027-03-25
MDE - São Paulo
69% AI deal score
$372
$458
Round trip
2027-03-07 – 2027-04-06
MDE - São Paulo
68% AI deal score
$371
$458
Round trip
2027-03-07 – 2027-03-18
MDE - São Paulo
69% AI deal score
$375
$458
Round trip
2027-03-07 – 2027-03-11
MDE - São Paulo
69% AI deal score
$389
$458
Round trip
2027-03-07 – 2027-03-16
MDE - São Paulo
69% AI deal score
$384
$458
Round trip
2027-04-01 – 2027-04-15
MDE - São Paulo
69% AI deal score
$397
$460
Round trip
2027-04-04 – 2027-04-15
MDE - São Paulo
69% AI deal score
$404
$460
Round trip
2027-04-01 – 2027-04-20
MDE - São Paulo
69% AI deal score
$392
$460
Round trip
2027-04-08 – 2027-04-20
MDE - São Paulo
70% AI deal score
$413
$461
Round trip
2027-04-04 – 2027-04-20
MDE - São Paulo
69% AI deal score
$398
$461
Round trip

Medellín to São Paulo: Overview

Insights for flights from Medellín to São Paulo

A typical journey from Medellín to São Paulo takes about 13h 10m, including connections. Given that most itineraries involve at least one stop, this duration reflects the overall travel time for this long-haul route. You can expect to spend a significant portion of your travel day in transit, with the median connecting flight time also being 13h 10m.

If you are looking for cheap flights from Medellín to São Paulo, right now fares are above the typical level. Prices for this route typically range from $574–$894, with a median of $692. Currently, 0% of recent fares are classified as a good price, indicating that finding a particularly low fare might require some flexibility or waiting for new deals to emerge. New deals for this route show up several times a week.

The cheapest months to fly from Medellín to São Paulo are July, with a median fare of $455, and December, with a median fare of $488. March also offers more competitive pricing, with a median fare of $551. Planning your trip during these months could result in significant savings compared to other times of the year.

Most itineraries for flights from Medellín to São Paulo connect at least once. In fact, 0% of recent fares were for direct flights from Medellín to São Paulo. For the vast majority of journeys, you should anticipate at least 2 stopovers, which contributes to the overall travel time for this route. This indicates that non-stop options are not available or are extremely rare for this particular long-haul journey.

The distance between Medellín and São Paulo is 4551 km, classifying this as a long-haul route. This considerable distance means that even direct flights, if available, would involve a substantial amount of time in the air. The long-haul classification also implies that itineraries will often include connections, further extending the total travel duration.

How much is a round trip from Medellín to São Paulo

Regular price: $421 - $598

Prices for flights from Medellín to São Paulo are currently within the regular range.

Regular prices for flights from Medellín to São Paulo typically range from 421 USD to 598 USD. The current lowest deal is 507 USD with LATAM Chile, for travel from Nov 28-Nov 30.

now $507

Low $421

High $598

The cheapest time to fly from Medellín to São Paulo

The cheapest month to fly from MDE to SAO is July, with a median price of $455. The most expensive month is February, with a median price of $784. Prices are generally lower from March to December.

July

Cheapest

Flights from $455

February

Most Expensive

Flights from $784

Feb

Mar

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Medellín to São Paulo

Copa Airlines

B&H Airlines

Sky Airline

Maersk Air

Last-minute flights going from Medellín to São Paulo

Wed, Oct 28

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$459

$550

One-way

Sun, Nov 1

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$566

$541

One-way

Sun, Nov 1

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Avianca

$497

$648

One-way

Thu, Nov 5

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$542

$541

One-way

Fri, Nov 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$540

$560

One-way

Sun, Nov 8

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$440

$525

One-way

Biggest price drops on these dates for flights from Medellín to São Paulo

5 nights

Nov 1 - Nov 6

$566 → $542

3 nights

Nov 5 - Nov 8

$542 → $542

5 nights

Feb 4 - Feb 9

$518 → $522

7 nights

Feb 4 - Feb 11

$512 → $517

Popular Airports to fly from Medellín to São Paulo

Medellín - São Paulo route insights

💸 Price insights

Recent fares are above the typical level

Recent fares for Medellín to São Paulo are above the typical level for this route.

📅 Best time to fly

Fly in July for prices around $455

Historically, July is the cheapest month to fly, with median prices around $455.

⏱️ Flight duration

Connecting flights average 13h 10m

Flights from Medellín to São Paulo typically involve connections, with a median duration of 13h 10m.

✈️ Airlines & availability

Connecting flights are dominant

This route is connecting-dominant; 0% of recent flights were direct.

🏆 Airline highlight

LATAM Chile offers a deal for $507

LATAM Chile recently offered a roundtrip for $507 from Medellín to São Paulo.

🎯 Booking tip

Deals appear regularly

Deals for flights from Medellín to São Paulo appear regularly, about every 30 days.

Medellín main airports to depart from

José María Córdova International (MDE)

Cheapest

José María Córdova International Airport is a good option for flights from Medellín to São Paulo.

📍 Located ~20 km from Medellín city center, accessible by car.

💸 Flights from ~$466

Olaya Herrera (EOH)

Olaya Herrera Airport is an alternative for your journey from Medellín to São Paulo.

📍 Located ~3 km from Medellín city center, accessible by car.

💸 Flights from ~$593

São Paulo main airports to arrive at

São Paulo–Guarulhos International (GRU)

Cheapest

São Paulo–Guarulhos International is a good option for flights from Medellín to São Paulo.

📍 ~21 km from São Paulo city center (reachable by car)

💸 Flights from ~$468

Airports nearby São Paulo used as alternative

Rio de Janeiro–Galeão International (GIG)

Cheapest

Consider this major international hub for high airline variety, though travel to São Paulo requires 5-6 hours.

📍 ~360 km from São Paulo (reachable by car)

💸 Flights from ~$434

Business & First Class Flight Deals to São Paulo

Discover luxury on the budget with premium cabin class on flights from Medellín to São Paulo.

Elite

Best Elite deals to São Paulo

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From MDE

Elite

Feb 28

São Paulo, Brazil

92% AI deal score

$1,305

$806

Save $499

LATAM Chile

Business Class

From MDE

Elite

Feb 25

São Paulo, Brazil

92% AI deal score

$1,304

$806

Save $498

LATAM Chile

Business Class

From MDE

Elite

Mar 02

São Paulo, Brazil

92% AI deal score

$1,274

$806

Save $468

LATAM Chile

Business Class

From MDE

Elite

Feb 23

São Paulo, Brazil

92% AI deal score

$1,304

$806

Save $498

LATAM Chile

Business Class

From MDE

Elite

Feb 22

São Paulo, Brazil

92% AI deal score

$1,302

$806

Save $496

LATAM Chile

Business Class

From MDE

Elite

Feb 26

São Paulo, Brazil

92% AI deal score

$1,304

$806

Save $498

LATAM Chile

Business Class

From MDE

Elite

Mar 01

São Paulo, Brazil

92% AI deal score

$1,287

$806

Save $481

LATAM Chile

Business Class

From MDE

Elite

Feb 25

São Paulo, Brazil

92% AI deal score

$1,304

$813

Save $491

LATAM Chile

Business Class

From MDE

Elite

Feb 28

São Paulo, Brazil

92% AI deal score

$1,305

$813

Save $492

LATAM Chile

Business Class

From MDE

Elite

Mar 02

São Paulo, Brazil

92% AI deal score

$1,290

$813

Save $477

LATAM Chile

Business Class

From MDE

Elite

Feb 23

São Paulo, Brazil

92% AI deal score

$1,303

$813

Save $490

LATAM Chile

Business Class

From MDE

Elite

Feb 26

São Paulo, Brazil

92% AI deal score

$1,303

$813

Save $490

LATAM Chile

Business Class

Frequently Asked Questions About Flights to São Paulo

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking flights in advance often provides more options and potentially lower prices, though last-minute deals can sometimes appear. Monitoring price trends for your desired travel period may help you decide the optimal booking time. Prices can fluctuate based on various factors.

Comparing nearby airports at both your origin and destination can sometimes lead to more economical flight options. While it may add to travel time, the savings on airfare can be significant. Always factor in the cost and convenience of ground transportation to and from these alternative airports.

Related routes

More routes from Medellín

Flights from Medellín to Aruba Flights from Medellín to Asunción Flights from Medellín to Barcelona Flights from Medellín to Bogotá Flights from Medellín to Cali Flights from Medellín to Cusco Flights from Medellín to Guatemala City Flights from Medellín to Panama City Flights from Medellín to Quito Flights from Medellín to Salta Flights from Medellín to San Andrés Flights from Medellín to Santo Domingo

Flights to São Paulo from other cities

Flights from Maringá to São Paulo Flights from Mendoza to São Paulo Flights from Mexico City to São Paulo Flights from Miami to São Paulo Flights from Montevideo to São Paulo Flights from Natal to São Paulo Flights from Navegantes to São Paulo Flights from Palmas to São Paulo Flights from Paramaribo to São Paulo Flights from Porto Alegre to São Paulo Flights from Recife to São Paulo Flights from Ribeirão Preto to São Paulo

Medellín to São Paulo: Overview

Insights for flights from Medellín to São Paulo

How much is a round trip from Medellín to São Paulo

Regular price: $421 - $598

Prices for flights from Medellín to São Paulo are currently within the regular range.

Regular prices for flights from Medellín to São Paulo typically range from 421 USD to 598 USD. The current lowest deal is 507 USD with LATAM Chile, for travel from Nov 28-Nov 30.

now $507

Low $421

High $598

The cheapest time to fly from Medellín to São Paulo

The cheapest month to fly from MDE to SAO is July, with a median price of $455. The most expensive month is February, with a median price of $784. Prices are generally lower from March to December.

July

Cheapest

Flights from $455

February

Most Expensive

Flights from $784

Feb

Mar

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Medellín to São Paulo

Copa Airlines

B&H Airlines

Sky Airline

Maersk Air

Last-minute flights going from Medellín to São Paulo

Wed, Oct 28

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$459

$550

One-way

Sun, Nov 1

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$566

$541

One-way

Sun, Nov 1

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Avianca

$497

$648

One-way

Thu, Nov 5

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$542

$541

One-way

Fri, Nov 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$540

$560

One-way

Sun, Nov 8

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

City Connexion Airlines

$440

$525

One-way

Biggest price drops on these dates for flights from Medellín to São Paulo

5 nights

Nov 1 - Nov 6

$566 → $542

3 nights

Nov 5 - Nov 8

$542 → $542

5 nights

Feb 4 - Feb 9

$518 → $522

7 nights

Feb 4 - Feb 11

$512 → $517

Popular Airports to fly from Medellín to São Paulo

Medellín - São Paulo route insights

💸 Price insights

Recent fares are above the typical level

Recent fares for Medellín to São Paulo are above the typical level for this route.

📅 Best time to fly

Fly in July for prices around $455

Historically, July is the cheapest month to fly, with median prices around $455.

⏱️ Flight duration

Connecting flights average 13h 10m

Flights from Medellín to São Paulo typically involve connections, with a median duration of 13h 10m.

✈️ Airlines & availability

Connecting flights are dominant

This route is connecting-dominant; 0% of recent flights were direct.

🏆 Airline highlight

LATAM Chile offers a deal for $507

LATAM Chile recently offered a roundtrip for $507 from Medellín to São Paulo.

🎯 Booking tip

Deals appear regularly

Deals for flights from Medellín to São Paulo appear regularly, about every 30 days.

Medellín main airports to depart from

José María Córdova International (MDE)

Cheapest

José María Córdova International Airport is a good option for flights from Medellín to São Paulo.

📍 Located ~20 km from Medellín city center, accessible by car.

💸 Flights from ~$466

Olaya Herrera (EOH)

Olaya Herrera Airport is an alternative for your journey from Medellín to São Paulo.

📍 Located ~3 km from Medellín city center, accessible by car.

💸 Flights from ~$593

São Paulo main airports to arrive at

São Paulo–Guarulhos International (GRU)

Cheapest

São Paulo–Guarulhos International is a good option for flights from Medellín to São Paulo.

📍 ~21 km from São Paulo city center (reachable by car)

💸 Flights from ~$468

Airports nearby São Paulo used as alternative

Rio de Janeiro–Galeão International (GIG)

Cheapest

Consider this major international hub for high airline variety, though travel to São Paulo requires 5-6 hours.

São Paulo, Brazil

92% AI deal score

$1,303

$813

Save $490

LATAM Chile

Business Class

Frequently Asked Questions About Flights to São Paulo

Cheap Flights from Medellín to São Paulo

Today’s best flight deals from Medellín to São Paulo

Medellín to São Paulo: Overview

Insights for flights from Medellín to São Paulo

How much is a round trip from Medellín to São Paulo

The cheapest time to fly from Medellín to São Paulo

Direct flights from Medellín to São Paulo

Last-minute flights going from Medellín to São Paulo

Biggest price drops on these dates for flights from Medellín to São Paulo

Popular Airports to fly from Medellín to São Paulo

Medellín - São Paulo route insights

Recent fares are above the typical level

Fly in July for prices around $455

Connecting flights average 13h 10m

Connecting flights are dominant

LATAM Chile offers a deal for $507

Deals appear regularly

Medellín main airports to depart from

São Paulo main airports to arrive at

Airports nearby São Paulo used as alternative

Business & First Class Flight Deals to São Paulo

Best Elite deals to São Paulo

Feb 28

Feb 25

Mar 02

Feb 23

Feb 22

Feb 26

Mar 01

Feb 25

Feb 28

Mar 02

Feb 23

Feb 26

Frequently Asked Questions About Flights to São Paulo

How can I find cheap flights from Medellín to São Paulo?

When should I book flights from Medellín to São Paulo?

Should I compare nearby airports for flights from Medellín to São Paulo?

Are direct flights from Medellín to São Paulo always the best option?

Can flexible travel dates help on Medellín to São Paulo flights?

What extra costs should I check before booking Medellín to São Paulo flights?

Related routes

More routes from Medellín

Flights to São Paulo from other cities

Medellín to São Paulo: Overview

Insights for flights from Medellín to São Paulo

How much is a round trip from Medellín to São Paulo

The cheapest time to fly from Medellín to São Paulo

Direct flights from Medellín to São Paulo

Last-minute flights going from Medellín to São Paulo

Biggest price drops on these dates for flights from Medellín to São Paulo

Popular Airports to fly from Medellín to São Paulo

Medellín - São Paulo route insights

Recent fares are above the typical level

Fly in July for prices around $455

Connecting flights average 13h 10m

Connecting flights are dominant

LATAM Chile offers a deal for $507

Deals appear regularly

Medellín main airports to depart from

São Paulo main airports to arrive at

Airports nearby São Paulo used as alternative

Business & First Class Flight Deals to São Paulo

Best Elite deals to São Paulo

Feb 28

Feb 25

Mar 02

Feb 23

Feb 22

Feb 26

Mar 01

Feb 25

Feb 28

Mar 02

Feb 23

Feb 26

Frequently Asked Questions About Flights to São Paulo

How can I find cheap flights from Medellín to São Paulo?

When should I book flights from Medellín to São Paulo?

Should I compare nearby airports for flights from Medellín to São Paulo?