Are direct flights from Medellín to São Paulo always the best option?

Direct flights are usually more convenient as they save time and avoid layovers. However, they are not always the cheapest option. Flights with one or more stops can sometimes be significantly more affordable, especially if you are flexible with your travel time.

Can flexible travel dates help on Medellín to São Paulo flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying on weekdays or during off-peak seasons often results in lower fares compared to weekends or popular holiday periods. Adjusting your departure or return by even a day or two may reveal better deals.

What extra costs should I check before booking Medellín to São Paulo flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factoring these into your total budget can help avoid surprises.

Flights From Medellín

To São Paulo

Cheap Flights from Medellín to São Paulo

Browse current best options from Medellín. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Medellín

RatePunk searches hundreds of travel sites at once for deals on flights to São Paulo

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Medellín to São Paulo

Explore current cheapest deals departing from Medellín to São Paulo

2026-08-06 – 2026-08-07
MDE - São Paulo
89% AI deal score
$542
$396
Round trip
2026-08-05 – 2026-08-07
MDE - São Paulo
89% AI deal score
$542
$396
Round trip
2026-08-21 – 2026-08-28
MDE - São Paulo
79% AI deal score
$491
$430
Round trip
2026-09-04 – 2026-09-11
MDE - São Paulo
73% AI deal score
$421
$434
Round trip
2026-08-14 – 2026-08-28
MDE - São Paulo
75% AI deal score
$448
$436
Round trip
2026-08-14 – 2026-08-21
MDE - São Paulo
78% AI deal score
$491
$436
Round trip
2026-08-06 – 2026-08-27
MDE - São Paulo
73% AI deal score
$431
$441
Round trip
2026-09-19 – 2026-10-15
MDE - São Paulo
72% AI deal score
$383
$441
Round trip
2026-08-05 – 2026-08-27
MDE - São Paulo
73% AI deal score
$428
$441
Round trip
2026-08-06 – 2026-08-21
MDE - São Paulo
74% AI deal score
$444
$441
Round trip

Medellín to São Paulo: Overview

Insights for flights from Medellín to São Paulo

A typical journey from Medellín to São Paulo takes about 19h 40m, including connections. Given that most itineraries on this route involve at least one stop, this duration reflects the common travel experience. Travelers should anticipate a significant journey time when planning their trip.

For those seeking cheap flights from Medellín to São Paulo, prices typically range from $507–$709, with a median of $589. Right now, fares are near the typical level for this route. Only 1% of recent fares were classified as a good price, indicating that finding significantly lower prices can be challenging.

The cheapest months to fly from Medellín to São Paulo are February and January, both with a median fare of $346. December also offers more competitive pricing, with a median fare of $405. Planning your travel during these months could result in notable savings.

Most itineraries from Medellín to São Paulo are connecting flights, as 0% of recent fares were non-stop. This means you should expect to make at least 2 connections on your journey. This route is classified as long-haul, covering a distance of 4551 km.

How much is a round trip from Medellín to São Paulo

Regular price: $437 - $610

Prices for flights from Medellín to São Paulo are currently below the regular range.

The regular price range for this route is $437 to $610. The current lowest deal is $428 with Avianca for travel from Aug 21-Aug 28.

now $428

Low $437

High $610

The cheapest time to fly from Medellín to São Paulo

The cheapest month to fly from MDE to SAO is January, with a median price of $346. The most expensive month is August, with a median price of $628. Prices are generally lower from January to December.

January

Cheapest

Flights from $346

August

Most Expensive

Flights from $628

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Medellín to São Paulo

Copa Airlines

LATAM Chile

City Connexion Airlines

Avianca

Last-minute flights going from Medellín to São Paulo

Wed, Aug 5

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$548

$478

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$449

$477

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$526

$478

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$573

$495

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$525

$496

One-way

Fri, Aug 7

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$498

$476

One-way

Biggest price drops on these dates for flights from Medellín to São Paulo

2 nights

Aug 12 - Aug 14

$541 → $435

20%

2 nights

Aug 25 - Aug 27

$521 → $436

16%

4 nights

Aug 10 - Aug 14

$543 → $460

15%

4 nights

Aug 6 - Aug 10

$573 → $495

14%

Popular Airports to fly from Medellín to São Paulo

Medellín - São Paulo route insights

💸 Price insights

Recent fares are below the typical level

Recent roundtrip fares from Medellín to São Paulo are below the typical level at $428.

📅 Best time to fly

Fly in February for the best prices

Historically, February is the cheapest month to fly from Medellín to São Paulo, with a median price of $346.

⏱️ Flight duration

Long-haul flights with 2+ stopovers

Flights from Medellín to São Paulo typically take 19h 40m, with a median of 2 stopovers.

✈️ Airlines & availability

Connecting flights only

There are no direct flights available. Connecting flights are offered by multiple airlines.

🏆 Airline highlight

Avianca offers a recent deal

Avianca recently offered a roundtrip fare for $428 from Medellín to São Paulo.

🎯 Booking tip

Deals are frequent on this route

Deals on flights from Medellín to São Paulo are frequent, appearing often in the last 30 days.

Medellín main airports to depart from

José María Córdova International (MDE)

Cheapest

José María Córdova International is the primary airport for flights from Medellín to São Paulo.

📍 ~18 km from Medellín city center (reachable by car).

💸 Flights from ~$410

São Paulo main airports to arrive at

São Paulo–Guarulhos International (GRU)

Cheapest

São Paulo–Guarulhos International is a key arrival airport for flights from Medellín to São Paulo.

📍 ~20 km from São Paulo city center (reachable by car)

💸 Flights from ~$472

Airports nearby São Paulo used as alternative

Rio de Janeiro–Galeão International (GIG)

Cheapest

This major international hub offers an extensive route network and high frequency of connecting flights.

📍 ~350 km from São Paulo (reachable by connecting flight or car)

💸 Flights from ~$493

Business & First Class Flight Deals to São Paulo

91% AI deal score

$1,698

$888

Save $810

Frequently Asked Questions About Flights to São Paulo

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can often reveal better deals. Also, looking into flights with layovers may sometimes present lower fares than direct options.

Booking flights in advance, often several months out, can sometimes secure better prices. However, prices can fluctuate, so monitoring fares over time may help you identify a good booking window. Weekday bookings might also offer different pricing compared to weekend bookings.

Comparing nearby airports at both your origin and destination can sometimes lead to more affordable flight options. Even if an airport is a bit further, the potential savings on airfare might outweigh the additional ground transportation costs. It's often worth checking all available options.

Related routes

More routes from Medellín

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Flights to São Paulo from other cities

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Medellín to São Paulo: Overview

Insights for flights from Medellín to São Paulo

How much is a round trip from Medellín to São Paulo

Regular price: $437 - $610

Prices for flights from Medellín to São Paulo are currently below the regular range.

The regular price range for this route is $437 to $610. The current lowest deal is $428 with Avianca for travel from Aug 21-Aug 28.

now $428

Low $437

High $610

The cheapest time to fly from Medellín to São Paulo

January

Cheapest

Flights from $346

August

Most Expensive

Flights from $628

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Medellín to São Paulo

Copa Airlines

LATAM Chile

City Connexion Airlines

Avianca

Last-minute flights going from Medellín to São Paulo

Wed, Aug 5

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$548

$478

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$449

$477

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$526

$478

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$573

$495

One-way

Thu, Aug 6

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$525

$496

One-way

Fri, Aug 7

⌛ Last-Minute

MDE - São Paulo

Medellín (MDE) - São Paulo (GRU)

Copa Airlines

$498

$476

One-way

Biggest price drops on these dates for flights from Medellín to São Paulo

2 nights

Aug 12 - Aug 14

$541 → $435

20%

2 nights

Aug 25 - Aug 27

$521 → $436

16%

4 nights

Aug 10 - Aug 14

$543 → $460

15%

4 nights

Aug 6 - Aug 10

$573 → $495

14%

Popular Airports to fly from Medellín to São Paulo