Are direct flights from San Francisco to Guayaquil always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, flights with connections can sometimes be more budget-friendly. Weighing the cost savings against the added travel time and potential for delays is often a good approach.

Can flexible travel dates help on San Francisco to Guayaquil flights?

Yes, being flexible with your travel dates can often lead to finding more affordable flight options. Prices can vary significantly depending on the day of the week or season. Adjusting your departure or return by a few days may result in noticeable savings.

What extra costs should I check before booking San Francisco to Guayaquil flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Understanding these additional fees can help you calculate the total cost of your trip.

Flights From San Francisco

To Guayaquil

Cheap Flights from San Francisco to Guayaquil

Browse current best options from San Francisco. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

San Francisco

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Prices updated 1 day ago

462 airlines compared

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Fares are subject to change and may not be available for all dates. (Data last updated Sep 15, 2026.)

Today’s best flight deals from San Francisco to Guayaquil

Explore current cheapest deals departing from San Francisco to Guayaquil

2026-10-10 – 2026-10-19
SFO - Guayaquil
78% AI deal score
$641
$544
Round trip
2026-10-19 – 2026-10-22
SFO - Guayaquil
84% AI deal score
$697
$544
Round trip
2026-11-12 – 2026-11-21
SFO - Guayaquil
75% AI deal score
$491
$552
Round trip
2026-10-10 – 2026-10-24
SFO - Guayaquil
80% AI deal score
$628
$555
Round trip
2026-10-20 – 2026-10-26
SFO - Guayaquil
81% AI deal score
$666
$568
Round trip
2026-10-10 – 2026-10-26
SFO - Guayaquil
79% AI deal score
$619
$568
Round trip
2026-10-10 – 2026-10-27
SFO - Guayaquil
79% AI deal score
$616
$569
Round trip
2026-10-20 – 2026-10-27
SFO - Guayaquil
81% AI deal score
$666
$569
Round trip
2026-10-10 – 2026-10-15
SFO - Guayaquil
82% AI deal score
$686
$569
Round trip
2026-10-10 – 2026-11-07
SFO - Guayaquil
79% AI deal score
$613
$569
Round trip

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

For cheap flights from San Francisco to Guayaquil, prices typically range from $283–$324, with a median of $315. Right now, current fares are significantly below the typical level. This indicates a favorable time for booking, with recent deals showing strong value for travelers.

When is the cheapest time to fly from San Francisco to Guayaquil? The most affordable month to fly is typically April, with a median fare of $233. Other cost-effective months include December, where the median fare is $257, and May, with a median of $299.

Most itineraries for this route connect at least once, as 0% of recent fares were for non-stop flights. When connections are necessary, the typical number of stopovers is 1. This means you should expect to make at least one stop on your journey.

How long is the flight from San Francisco to Guayaquil? A typical journey, including connections, takes approximately 13h 51m. This duration reflects the long-haul nature of the route, accounting for the necessary stopovers between the two cities.

The distance between San Francisco and Guayaquil is 6,217 kilometers. This classifies the route as a long-haul journey, indicating a significant travel distance that typically involves extended flight times and often requires connections.

How much is a round trip from San Francisco to Guayaquil

Regular price: $431 - $735

Prices for flights from San Francisco to Guayaquil are currently within the regular range.

The regular price range for flights from San Francisco to Guayaquil is between $431 and $735. The current lowest deal is $549 with Copa Airlines for travel from Nov 12-Nov 21.

now $549

Low $431

High $735

The cheapest time to fly from San Francisco to Guayaquil

The cheapest month to fly from San Francisco to Guayaquil is April, with a median price of $233. The most expensive month is January, with a median price of $385. Prices are generally lower from March to December.

April

Cheapest

Flights from $233

January

Most Expensive

Flights from $385

Jan

Mar

Apr

May

Jun

Oct

Dec

Direct flights from San Francisco to Guayaquil

Copa Airlines

JetBlue Airways

Frontier Airlines

Avianca

Last-minute flights going from San Francisco to Guayaquil

Wed, Oct 7

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines

$629

$625

One-way

Wed, Oct 7

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Avianca

$641

$678

One-way

Thu, Oct 8

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Copa Airlines

$702

$614

One-way

Sat, Oct 10

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

$641

$544

One-way

Sat, Oct 10

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

JetBlue Airways

$628

$552

One-way

Sat, Oct 10

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

JetBlue Airways

$616

$570

One-way

Biggest price drops on these dates for flights from San Francisco to Guayaquil

2 nights

Oct 13 - Oct 15

$705 → $576

18%

2 nights

Oct 20 - Oct 22

$702 → $576

18%

4 nights

Oct 20 - Oct 24

$696 → $586

16%

7 nights

Oct 13 - Oct 20

$667 → $571

14%

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from San Francisco to Guayaquil are below the typical level for this route.

📅 Best time to fly

April is historically cheapest at $233

Historically, April is the cheapest month to fly from San Francisco to Guayaquil, at $233.

⏱️ Flight duration

Typical flight time is 13h 51m

The typical flight duration from San Francisco to Guayaquil is 13 hours 51 minutes with one stop.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant for this route, with a median of 1 stopover.

🏆 Airline highlight

Copa Airlines offers 48 deals

Copa Airlines has 48 deals, making it a frequent option for this route.

🎯 Booking tip

Deals appear regularly

Deals for flights from San Francisco to Guayaquil appear regularly, offering frequent opportunities.

San Francisco main airports to depart from

San Francisco International (SFO)

Cheapest

San Francisco International is a convenient option for flights from San Francisco to Guayaquil.

📍 ~18 km from city center (reachable by car or train)

💸 Flights from ~$503

Guayaquil main airports to arrive at

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International Airport is the primary gateway for flights to Guayaquil.

📍 ~5 km from city center (reachable by car)

💸 Flights from ~$503

Airports nearby Guayaquil used as alternative

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International is a primary international hub for Ecuador, offering extensive route networks and frequent flights.

📍 ~270 km from Guayaquil (significant road travel time, approx. 7-8 hours, or fly between cities; high altitude may affect some travelers).

💸 Flights from ~$593

Business & First Class Flight Deals to Guayaquil

Discover luxury on the budget with premium cabin class on flights from San Francisco to Guayaquil.

Elite

Best Elite deals to Guayaquil

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From SFO

Elite

Oct 13

Guayaquil, Ecuador

96% AI deal score

$4,598

$1,219

Save $3,379

United Airlines

Business Class

From SFO

Elite

Feb 04

Guayaquil, Ecuador

95% AI deal score

$4,314

$1,388

Save $2,926

United Airlines

Business Class

From SFO

Elite

Dec 09

Guayaquil, Ecuador

94% AI deal score

$4,672

$1,642

Save $3,030

United Airlines

Business Class

From SFO

Elite

Oct 21

Guayaquil, Ecuador

94% AI deal score

$4,446

$2,200

Save $2,246

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Oct 21

Guayaquil, Ecuador

94% AI deal score

$4,457

$2,233

Save $2,224

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Sep 26

Guayaquil, Ecuador

94% AI deal score

$4,666

$2,267

Save $2,399

Aeroméxico, +1

Business Class

From SFO

Elite

Sep 25

Guayaquil, Ecuador

94% AI deal score

$4,705

$2,267

Save $2,438

Aeroméxico, +1

Business Class

From SFO

Elite

Oct 18

Guayaquil, Ecuador

94% AI deal score

$4,446

$2,271

Save $2,175

Aeroméxico, +1

Business Class

From SFO

Elite

Oct 21

Guayaquil, Ecuador

94% AI deal score

$4,509

$2,293

Save $2,216

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Oct 21

Guayaquil, Ecuador

94% AI deal score

$4,791

$2,448

Save $2,343

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Feb 07

Guayaquil, Ecuador

93% AI deal score

$4,304

$1,662

Save $2,642

United Airlines

Business Class

From SFO

Elite

Mar 02

Guayaquil, Ecuador

93% AI deal score

$4,266

$1,671

Save $2,595

United Airlines

Business Class

Frequently Asked Questions About Flights to Guayaquil

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across various airlines and booking sites can often reveal better deals. Setting up price alerts may also notify you when fares drop.

Booking in advance can often secure better prices, though the ideal booking window can vary. Prices may fluctuate, so monitoring fares over time can help you decide when to purchase your tickets. Weekday bookings might sometimes offer different pricing compared to weekends.

Comparing flights from nearby airports can sometimes provide more options or different pricing. While it may add to your travel time, checking alternative departure or arrival points could potentially lead to savings. Always factor in ground transportation costs and convenience.

Related routes

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Flights to Guayaquil from other cities

Flights from Aruba to Guayaquil Flights from Bogotá to Guayaquil Flights from Caracas to Guayaquil Flights from Fort Lauderdale to Guayaquil Flights from Houston to Guayaquil Flights from La Paz to Guayaquil Flights from Lima to Guayaquil Flights from Los Angeles to Guayaquil Flights from Medellín to Guayaquil Flights from Mexico City to Guayaquil Flights from Quito to Guayaquil Flights from Singapore to Guayaquil

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

How much is a round trip from San Francisco to Guayaquil

Regular price: $431 - $735

Prices for flights from San Francisco to Guayaquil are currently within the regular range.

The regular price range for flights from San Francisco to Guayaquil is between $431 and $735. The current lowest deal is $549 with Copa Airlines for travel from Nov 12-Nov 21.

now $549

Low $431

High $735

The cheapest time to fly from San Francisco to Guayaquil

April

Cheapest

Flights from $233

January

Most Expensive

Flights from $385

Jan

Mar

Apr

May

Jun

Oct

Dec

Direct flights from San Francisco to Guayaquil

Copa Airlines

JetBlue Airways

Frontier Airlines

Avianca

Last-minute flights going from San Francisco to Guayaquil

Wed, Oct 7

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines

$629

$625

One-way

Wed, Oct 7

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Avianca

$641

$678

One-way

Thu, Oct 8

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Copa Airlines

$702

$614

One-way

Sat, Oct 10

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

$641

$544

One-way

Sat, Oct 10

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

JetBlue Airways

$628

$552

One-way

Sat, Oct 10

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

JetBlue Airways

$616

$570

One-way

Biggest price drops on these dates for flights from San Francisco to Guayaquil

2 nights

Oct 13 - Oct 15

$705 → $576

18%

2 nights

Oct 20 - Oct 22

$702 → $576

18%

4 nights

Oct 20 - Oct 24

$696 → $586

16%

7 nights

Oct 13 - Oct 20

$667 → $571

14%

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from San Francisco to Guayaquil are below the typical level for this route.

📅 Best time to fly

April is historically cheapest at $233

Historically, April is the cheapest month to fly from San Francisco to Guayaquil, at $233.

⏱️ Flight duration

Typical flight time is 13h 51m

The typical flight duration from San Francisco to Guayaquil is 13 hours 51 minutes with one stop.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant for this route, with a median of 1 stopover.

🏆 Airline highlight

Copa Airlines offers 48 deals

Copa Airlines has 48 deals, making it a frequent option for this route.

🎯 Booking tip

Deals appear regularly

Deals for flights from San Francisco to Guayaquil appear regularly, offering frequent opportunities.

San Francisco main airports to depart from

San Francisco International (SFO)

Cheapest

San Francisco International is a convenient option for flights from San Francisco to Guayaquil.

📍 ~18 km from city center (reachable by car or train)

💸 Flights from ~$503

Guayaquil main airports to arrive at

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International Airport is the primary gateway for flights to Guayaquil.

📍 ~5 km from city center (reachable by car)

💸 Flights from ~$503

Airports nearby Guayaquil used as alternative

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International is a primary international hub for Ecuador, offering extensive route networks and frequent flights.

Guayaquil, Ecuador

93% AI deal score

$4,266

$1,671

Save $2,595

United Airlines

Business Class

Frequently Asked Questions About Flights to Guayaquil

Cheap Flights from San Francisco to Guayaquil

Today’s best flight deals from San Francisco to Guayaquil

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

How much is a round trip from San Francisco to Guayaquil

The cheapest time to fly from San Francisco to Guayaquil

Direct flights from San Francisco to Guayaquil

Last-minute flights going from San Francisco to Guayaquil

Biggest price drops on these dates for flights from San Francisco to Guayaquil

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

Recent fares are below the typical level

April is historically cheapest at $233

Typical flight time is 13h 51m

Connecting flights are dominant

Copa Airlines offers 48 deals

Deals appear regularly

San Francisco main airports to depart from

Guayaquil main airports to arrive at

Airports nearby Guayaquil used as alternative

Business & First Class Flight Deals to Guayaquil

Best Elite deals to Guayaquil

Oct 13

Feb 04

Dec 09

Oct 21

Oct 21

Sep 26

Sep 25

Oct 18

Oct 21

Oct 21

Feb 07

Mar 02

Frequently Asked Questions About Flights to Guayaquil

How can I find cheap flights from San Francisco to Guayaquil?

When should I book flights from San Francisco to Guayaquil?

Should I compare nearby airports for flights from San Francisco to Guayaquil?

Are direct flights from San Francisco to Guayaquil always the best option?

Can flexible travel dates help on San Francisco to Guayaquil flights?

What extra costs should I check before booking San Francisco to Guayaquil flights?

Related routes

More routes from San Francisco

Flights to Guayaquil from other cities

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

How much is a round trip from San Francisco to Guayaquil

The cheapest time to fly from San Francisco to Guayaquil

Direct flights from San Francisco to Guayaquil

Last-minute flights going from San Francisco to Guayaquil

Biggest price drops on these dates for flights from San Francisco to Guayaquil

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

Recent fares are below the typical level

April is historically cheapest at $233

Typical flight time is 13h 51m

Connecting flights are dominant

Copa Airlines offers 48 deals

Deals appear regularly

San Francisco main airports to depart from

Guayaquil main airports to arrive at

Airports nearby Guayaquil used as alternative

Business & First Class Flight Deals to Guayaquil

Best Elite deals to Guayaquil

Oct 13

Feb 04

Dec 09

Oct 21

Oct 21

Sep 26

Sep 25

Oct 18

Oct 21

Oct 21

Feb 07

Mar 02

Frequently Asked Questions About Flights to Guayaquil

How can I find cheap flights from San Francisco to Guayaquil?

When should I book flights from San Francisco to Guayaquil?

Should I compare nearby airports for flights from San Francisco to Guayaquil?