Are direct flights from San Francisco to Guayaquil always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers, but they are not always the most economical choice. Flights with one or more stops can often be more affordable. Consider your priorities, whether it's speed or cost savings, when making your decision.

Can flexible travel dates help on San Francisco to Guayaquil flights?

Yes, being flexible with your travel dates can significantly impact the price of your flight. Mid-week flights or those during off-peak seasons often have lower fares than weekend or holiday travel. Adjusting your departure or return by a few days may lead to considerable savings.

What extra costs should I check before booking San Francisco to Guayaquil flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From San Francisco

To Guayaquil

Cheap Flights from San Francisco to Guayaquil

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Prices updated 7 days ago

483 airlines compared

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Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)

Today’s best flight deals from San Francisco to Guayaquil

Explore current cheapest deals departing from San Francisco to Guayaquil

2027-02-01 – 2027-02-08
SFO - Guayaquil
73% AI deal score
$523
$556
Round trip
2027-01-19 – 2027-01-25
SFO - Guayaquil
73% AI deal score
$524
$558
Round trip
2027-01-12 – 2027-01-25
SFO - Guayaquil
73% AI deal score
$499
$559
Round trip
2027-01-19 – 2027-02-08
SFO - Guayaquil
73% AI deal score
$507
$562
Round trip
2027-01-12 – 2027-02-08
SFO - Guayaquil
73% AI deal score
$494
$563
Round trip
2027-01-12 – 2027-02-02
SFO - Guayaquil
73% AI deal score
$494
$564
Round trip
2027-01-19 – 2027-02-02
SFO - Guayaquil
73% AI deal score
$512
$564
Round trip
2027-01-12 – 2027-01-19
SFO - Guayaquil
73% AI deal score
$511
$564
Round trip
2027-01-26 – 2027-02-08
SFO - Guayaquil
73% AI deal score
$514
$564
Round trip
2027-01-26 – 2027-02-02
SFO - Guayaquil
73% AI deal score
$528
$565
Round trip

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

For travelers looking for cheap flights from San Francisco to Guayaquil, January stands out as the most affordable month, with a median fare of just $329. Other relatively cheaper months include August, with a median fare of $989, and October, where the median fare is $1058. Planning your trip around these months could lead to significant savings.

Fares for this route typically range from $887 to $1207, with a median price of $1058. Right now, current fares are near the typical level for this route. However, the share of recent fares classified as a good price is 0%, indicating that finding exceptional deals can be challenging, and new deals are infrequent — a price alert helps.

When considering how long is the flight from San Francisco to Guayaquil, a typical journey, including connections, takes approximately 13h 51m. This reflects that most itineraries connect at least once, as 0% of recent fares were for non-stop flights. Most connecting itineraries involve 3 stopovers before reaching Guayaquil.

The route from San Francisco to Guayaquil covers a substantial distance of 6217 kilometers. This classifies it as a long-haul journey, meaning you should expect a significant travel time due to the considerable distance between the two cities.

How much is a round trip from San Francisco to Guayaquil

Regular price: $456 - $971

Prices for flights from San Francisco to Guayaquil are currently within the regular range.

The regular price range for this route is between $456 and $971. The current lowest deal is $517 with Frontier Airlines for travel from Jan 19 to Jan 25.

now $517

Low $456

High $971

The cheapest time to fly from San Francisco to Guayaquil

The cheapest month to fly from San Francisco to Guayaquil is January, with a median price of $329. The most expensive month is September, with a median price of $1143. Prices are generally lower from January to October.

January

Cheapest

Flights from $329

September

Most Expensive

Flights from $1,143

Jan

Aug

Sep

Oct

Direct flights from San Francisco to Guayaquil

Frontier Airlines

JetBlue Airways

Copa Airlines

Alaska Airlines, Inc.

Last-minute flights going from San Francisco to Guayaquil

Mon, Jan 11

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, JetBlue Airways

$499

$506

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$499

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$494

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$494

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$494

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$499

$691

One-way

Biggest price drops on these dates for flights from San Francisco to Guayaquil

3 nights

Jan 22 - Jan 25

$540 → $499

4 nights

Jan 22 - Jan 26

$540 → $505

7 nights

Jan 26 - Feb 2

$525 → $503

6 nights

Jan 26 - Feb 1

$524 → $503

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

💸 Price insights

Recent fares are near the typical level

Recent fares for flights from San Francisco to Guayaquil are near the typical level.

📅 Best time to fly

January is historically the cheapest month to fly

Historically, January is the cheapest month to fly from San Francisco to Guayaquil, with a median price of $329.

⏱️ Flight duration

Flights are typically 13h 51m long

Flights from San Francisco to Guayaquil typically take 13 hours and 51 minutes, including layovers.

✈️ Airlines & availability

Connecting flights are dominant on this route

Connecting flights are dominant on this route, with a median of 3 stopovers for connecting itineraries.

🏆 Airline highlight

Frontier Airlines offers a deal for $517

A recent deal from Frontier Airlines offers a flight for $517, departing on January 19 and returning on January 25.

🎯 Booking tip

Deals on this route are rare

Deals for flights from San Francisco to Guayaquil are rare, based on recent 30-day trends.

San Francisco main airports to depart from

San Francisco International (SFO)

Cheapest

San Francisco International Airport is a convenient option for flights from San Francisco to Guayaquil.

📍 ~18 km from city center (reachable by car or train)

💸 Flights from ~$613

Guayaquil main airports to arrive at

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International Airport is the primary airport serving Guayaquil, Ecuador.

📍 ~5 km from Guayaquil (reachable by car)

💸 Flights from ~$625

Airports nearby Guayaquil used as alternative

Mariscal Sucre International (UIO)

Cheapest

This airport is the primary international hub for Ecuador, offering the most extensive route network.

📍 ~270 km from Guayaquil (reachable by car, approx. 7-8 hours drive, or by connecting flight)

💸 Flights from ~$638

Business & First Class Flight Deals to Guayaquil

Discover luxury on the budget with premium cabin class on flights from San Francisco to Guayaquil.

Elite

Best Elite deals to Guayaquil

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From SFO

Elite

Dec 07

Guayaquil, Ecuador

94% AI deal score

$4,332

$2,127

Save $2,205

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 07

Guayaquil, Ecuador

94% AI deal score

$4,334

$2,132

Save $2,202

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 07

Guayaquil, Ecuador

94% AI deal score

$4,275

$2,134

Save $2,141

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 07

Guayaquil, Ecuador

94% AI deal score

$4,314

$2,137

Save $2,177

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 07

Guayaquil, Ecuador

94% AI deal score

$4,556

$2,249

Save $2,307

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 09

Guayaquil, Ecuador

94% AI deal score

$4,457

$2,251

Save $2,206

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 08

Guayaquil, Ecuador

94% AI deal score

$4,363

$2,251

Save $2,112

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 08

Guayaquil, Ecuador

94% AI deal score

$4,573

$2,368

Save $2,205

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 05

Guayaquil, Ecuador

93% AI deal score

$4,314

$2,247

Save $2,067

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 09

Guayaquil, Ecuador

93% AI deal score

$4,339

$2,247

Save $2,092

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 08

Guayaquil, Ecuador

93% AI deal score

$4,335

$2,247

Save $2,088

Alaska Airlines, Inc., +1

Business Class

From SFO

Elite

Dec 05

Guayaquil, Ecuador

93% AI deal score

$4,335

$2,251

Save $2,084

Alaska Airlines, Inc., +1

Business Class

Frequently Asked Questions About Flights to Guayaquil

To find more affordable flights, consider being flexible with your travel dates and times. Using flight comparison sites can help you compare options from various providers. Looking into flights with layovers may also present lower prices than direct routes.

Booking flights in advance often provides more competitive prices, though the ideal booking window can vary. Generally, purchasing tickets several weeks or months before your intended departure may result in better deals. Prices can fluctuate, so monitoring fares is often helpful.

Comparing nearby airports at both your origin and destination can sometimes uncover more affordable flight options. While it may add to your ground travel, the savings on airfare could be significant. Always factor in the cost and convenience of transportation to and from alternative airports.

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Flights to Guayaquil from other cities

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San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

How much is a round trip from San Francisco to Guayaquil

Regular price: $456 - $971

Prices for flights from San Francisco to Guayaquil are currently within the regular range.

The regular price range for this route is between $456 and $971. The current lowest deal is $517 with Frontier Airlines for travel from Jan 19 to Jan 25.

now $517

Low $456

High $971

The cheapest time to fly from San Francisco to Guayaquil

January

Cheapest

Flights from $329

September

Most Expensive

Flights from $1,143

Jan

Aug

Sep

Oct

Direct flights from San Francisco to Guayaquil

Frontier Airlines

JetBlue Airways

Copa Airlines

Alaska Airlines, Inc.

Last-minute flights going from San Francisco to Guayaquil

Mon, Jan 11

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, JetBlue Airways

$499

$506

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$499

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$494

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$494

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$494

$690

One-way

Tue, Jan 12

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines, Copa Airlines

$499

$691

One-way

Biggest price drops on these dates for flights from San Francisco to Guayaquil

3 nights

Jan 22 - Jan 25

$540 → $499

4 nights

Jan 22 - Jan 26

$540 → $505

7 nights

Jan 26 - Feb 2

$525 → $503

6 nights

Jan 26 - Feb 1

$524 → $503

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

💸 Price insights

Recent fares are near the typical level

Recent fares for flights from San Francisco to Guayaquil are near the typical level.

📅 Best time to fly

January is historically the cheapest month to fly

Historically, January is the cheapest month to fly from San Francisco to Guayaquil, with a median price of $329.

⏱️ Flight duration

Flights are typically 13h 51m long

Flights from San Francisco to Guayaquil typically take 13 hours and 51 minutes, including layovers.

✈️ Airlines & availability

Connecting flights are dominant on this route

Connecting flights are dominant on this route, with a median of 3 stopovers for connecting itineraries.

🏆 Airline highlight

Frontier Airlines offers a deal for $517

A recent deal from Frontier Airlines offers a flight for $517, departing on January 19 and returning on January 25.

🎯 Booking tip

Deals on this route are rare

Deals for flights from San Francisco to Guayaquil are rare, based on recent 30-day trends.

San Francisco main airports to depart from

San Francisco International (SFO)

Cheapest

San Francisco International Airport is a convenient option for flights from San Francisco to Guayaquil.

📍 ~18 km from city center (reachable by car or train)

💸 Flights from ~$613

Guayaquil main airports to arrive at

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International Airport is the primary airport serving Guayaquil, Ecuador.

📍 ~5 km from Guayaquil (reachable by car)

💸 Flights from ~$625

Airports nearby Guayaquil used as alternative

Mariscal Sucre International (UIO)

Cheapest

This airport is the primary international hub for Ecuador, offering the most extensive route network.

Guayaquil, Ecuador

93% AI deal score

$4,335

$2,251

Save $2,084

Alaska Airlines, Inc., +1

Business Class

Frequently Asked Questions About Flights to Guayaquil

Cheap Flights from San Francisco to Guayaquil

Today’s best flight deals from San Francisco to Guayaquil

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

How much is a round trip from San Francisco to Guayaquil

The cheapest time to fly from San Francisco to Guayaquil

Direct flights from San Francisco to Guayaquil

Last-minute flights going from San Francisco to Guayaquil

Biggest price drops on these dates for flights from San Francisco to Guayaquil

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

Recent fares are near the typical level

January is historically the cheapest month to fly

Flights are typically 13h 51m long

Connecting flights are dominant on this route

Frontier Airlines offers a deal for $517

Deals on this route are rare

San Francisco main airports to depart from

Guayaquil main airports to arrive at

Airports nearby Guayaquil used as alternative

Business & First Class Flight Deals to Guayaquil

Best Elite deals to Guayaquil

Dec 07

Dec 07

Dec 07

Dec 07

Dec 07

Dec 09

Dec 08

Dec 08

Dec 05

Dec 09

Dec 08

Dec 05

Frequently Asked Questions About Flights to Guayaquil

How can I find cheap flights from San Francisco to Guayaquil?

When should I book flights from San Francisco to Guayaquil?

Should I compare nearby airports for flights from San Francisco to Guayaquil?

Are direct flights from San Francisco to Guayaquil always the best option?

Can flexible travel dates help on San Francisco to Guayaquil flights?

What extra costs should I check before booking San Francisco to Guayaquil flights?

Related routes

More routes from San Francisco

Flights to Guayaquil from other cities

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

How much is a round trip from San Francisco to Guayaquil

The cheapest time to fly from San Francisco to Guayaquil

Direct flights from San Francisco to Guayaquil

Last-minute flights going from San Francisco to Guayaquil

Biggest price drops on these dates for flights from San Francisco to Guayaquil

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

Recent fares are near the typical level

January is historically the cheapest month to fly

Flights are typically 13h 51m long

Connecting flights are dominant on this route

Frontier Airlines offers a deal for $517

Deals on this route are rare

San Francisco main airports to depart from

Guayaquil main airports to arrive at

Airports nearby Guayaquil used as alternative

Business & First Class Flight Deals to Guayaquil

Best Elite deals to Guayaquil

Dec 07

Dec 07

Dec 07

Dec 07

Dec 07

Dec 09

Dec 08

Dec 08

Dec 05

Dec 09

Dec 08

Dec 05

Frequently Asked Questions About Flights to Guayaquil

How can I find cheap flights from San Francisco to Guayaquil?

When should I book flights from San Francisco to Guayaquil?

Should I compare nearby airports for flights from San Francisco to Guayaquil?