Are direct flights from San Francisco to Guayaquil always the best option?

Direct flights offer convenience and save travel time, but they are not always the most budget-friendly choice. Flights with layovers can often be less expensive, though they extend your journey. Consider your priorities for cost versus travel duration.

Can flexible travel dates help on San Francisco to Guayaquil flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Mid-week flights or traveling during off-peak seasons often present more affordable fares. Adjusting your departure or return by a few days may result in considerable savings.

What extra costs should I check before booking San Francisco to Guayaquil flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. These additional fees can affect the total price of your trip.

Flights From San Francisco

To Guayaquil

Cheap Flights from San Francisco to Guayaquil

Browse current best options from San Francisco. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

San Francisco

RatePunk searches hundreds of travel sites at once for deals on flights to Guayaquil

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from San Francisco to Guayaquil

Explore current cheapest deals departing from San Francisco to Guayaquil

2026-10-07 – 2026-10-18
SFO - Guayaquil
81% AI deal score
$652
$555
Round trip
2027-01-07 – 2027-01-25
SFO - Guayaquil
79% AI deal score
$598
$556
Round trip
2026-10-15 – 2026-10-25
SFO - Guayaquil
77% AI deal score
$665
$578
Round trip
2027-01-27 – 2027-02-06
SFO - Guayaquil
75% AI deal score
$630
$579
Round trip
2026-08-12 – 2026-08-18
SFO - Guayaquil
80% AI deal score
$659
$582
Round trip
2026-08-18 – 2026-08-24
SFO - Guayaquil
79% AI deal score
$651
$587
Round trip
2026-08-14 – 2026-08-20
SFO - Guayaquil
79% AI deal score
$651
$596
Round trip
2026-09-06 – 2026-09-10
SFO - Guayaquil
73% AI deal score
$609
$619
Round trip
2026-09-11 – 2026-09-22
SFO - Guayaquil
72% AI deal score
$559
$625
Round trip
2026-09-06 – 2026-09-22
SFO - Guayaquil
72% AI deal score
$552
$626
Round trip

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

For travelers planning cheap flights from San Francisco to Guayaquil, the cheapest month to fly is April, with a median fare of $233. This is followed by December, where the median fare is $257, and May, with a median fare of $299. These months offer the most favorable pricing for this route.

Fares for flights from San Francisco to Guayaquil typically range from $283–$324, with a median of $315. Right now, current fares are significantly below the typical level for this route, indicating a favorable time to consider booking. New deals for this route show up several times a week, suggesting regular opportunities to find good prices.

Most itineraries for this route connect at least once, as 0% of recent fares from San Francisco to Guayaquil were for direct flights. For connecting itineraries, the typical number of connections is 1. This means you should expect at least one stop on your journey.

A typical journey from San Francisco to Guayaquil, including connections, takes approximately 13h 51m. This duration accounts for the common connecting itineraries on this long-haul route. The overall travel time can vary depending on the specific layovers and airlines chosen.

The distance between San Francisco and Guayaquil is 6217 km, classifying this as a long-haul route. This distance typically involves significant travel time and often requires connecting flights to reach the destination.

How much is a round trip from San Francisco to Guayaquil

Regular price: $519 - $981

Prices for flights from San Francisco to Guayaquil are currently within the regular range.

Regular prices for flights from San Francisco to Guayaquil typically range from $519 to $981. The current lowest deal is $532 on Kayak for travel from Jan 11-Jan 18.

now $532

Low $519

High $981

The cheapest time to fly from San Francisco to Guayaquil

The cheapest month to fly from SFO to GYE is April, with a median price of $233. The most expensive month is January, with a median price of $385. Prices are generally lower from March to December.

April

Cheapest

Flights from $233

January

Most Expensive

Flights from $385

Jan

Mar

Apr

May

Jun

Oct

Dec

Direct flights from San Francisco to Guayaquil

Copa Airlines

Frontier Airlines

JetBlue Airways

Avianca

Last-minute flights going from San Francisco to Guayaquil

Sun, Jul 26

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$953

$754

One-way

Sun, Jul 26

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$947

$754

One-way

Mon, Jul 27

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$953

$650

One-way

Mon, Jul 27

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$951

$650

One-way

Mon, Aug 17

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Copa Airlines

$635

$599

One-way

Tue, Aug 18

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines

$659

$625

One-way

Biggest price drops on these dates for flights from San Francisco to Guayaquil

3 nights

Jul 27 - Jul 30

$953 → $650

32%

2 nights

Jul 27 - Jul 29

$951 → $650

32%

3 nights

Jul 26 - Jul 29

$953 → $754

21%

4 nights

Jul 26 - Jul 30

$947 → $754

20%

Popular Airports to fly from San Francisco to Guayaquil

San Francisco - Guayaquil route insights

💸 Price insights

Recent fares are near the typical level

Recent fares from San Francisco to Guayaquil are near the typical level at $532.

📅 Best time to fly

April is historically cheapest

Historically, April is the cheapest month to fly from San Francisco to Guayaquil, with a median price of $233.

⏱️ Flight duration

Connecting flights take 13h 51m

The typical flight duration from San Francisco to Guayaquil is 13h 51m, with 1 stopover.

✈️ Airlines & availability

Connecting flights only

There are no direct flights. Connecting flights are available from Copa Airlines, Frontier Airlines, JetBlue Airways, and Avianca.

🏆 Airline highlight

Copa Airlines has 18 deals

Copa Airlines has 18 deals for connecting flights from San Francisco to Guayaquil.

🎯 Booking tip

Deals are regular

Deals for flights from San Francisco to Guayaquil are available on a regular basis.

San Francisco main airports to depart from

San Francisco International (SFO)

Cheapest

San Francisco International is a good option for flights from San Francisco to Guayaquil.

📍 ~20 km from San Francisco (reachable by car)

💸 Flights from ~$543

Guayaquil main airports to arrive at

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International Airport is a good choice for direct access to Guayaquil.

📍 ~5 km from city center (reachable by car)

💸 Flights from ~$543

Airports nearby Guayaquil used as alternative

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International is the primary international hub for Ecuador, offering extensive flight connections to Guayaquil.

📍 ~270 km from Guayaquil (reachable by car, approx. 7-8 hours travel time).

💸 Flights from ~$579

Business & First Class Flight Deals to Guayaquil

91% AI deal score

$4,402

$2,031

Save $2,371

Frequently Asked Questions About Flights to Guayaquil

To find more affordable flights, consider being flexible with your travel dates and times. Using flight comparison sites can help you survey various options. Looking into different airlines, including budget carriers, may also reveal better deals.

Booking in advance often provides more options and potentially lower prices, especially for international routes. However, last-minute deals can sometimes appear, though they are less predictable. Monitoring price trends can help you decide on an optimal booking time.

Comparing nearby airports at both your origin and destination can sometimes lead to more economical flight options. While it may add to your ground travel, the potential savings on airfare can be significant. Always factor in the total cost and convenience.

Related routes

More routes from San Francisco

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Flights to Guayaquil from other cities

Flights from Aruba to Guayaquil Flights from Bogotá to Guayaquil Flights from Caracas to Guayaquil Flights from Fort Lauderdale to Guayaquil Flights from Houston to Guayaquil Flights from La Paz to Guayaquil Flights from Lima to Guayaquil Flights from Los Angeles to Guayaquil Flights from Medellín to Guayaquil Flights from Mexico City to Guayaquil Flights from Quito to Guayaquil Flights from Singapore to Guayaquil

San Francisco to Guayaquil: Overview

Insights for flights from San Francisco to Guayaquil

How much is a round trip from San Francisco to Guayaquil

Regular price: $519 - $981

Prices for flights from San Francisco to Guayaquil are currently within the regular range.

Regular prices for flights from San Francisco to Guayaquil typically range from $519 to $981. The current lowest deal is $532 on Kayak for travel from Jan 11-Jan 18.

now $532

Low $519

High $981

The cheapest time to fly from San Francisco to Guayaquil

The cheapest month to fly from SFO to GYE is April, with a median price of $233. The most expensive month is January, with a median price of $385. Prices are generally lower from March to December.

April

Cheapest

Flights from $233

January

Most Expensive

Flights from $385

Jan

Mar

Apr

May

Jun

Oct

Dec

Direct flights from San Francisco to Guayaquil

Copa Airlines

Frontier Airlines

JetBlue Airways

Avianca

Last-minute flights going from San Francisco to Guayaquil

Sun, Jul 26

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$953

$754

One-way

Sun, Jul 26

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$947

$754

One-way

Mon, Jul 27

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$953

$650

One-way

Mon, Jul 27

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

American Airlines

$951

$650

One-way

Mon, Aug 17

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Copa Airlines

$635

$599

One-way

Tue, Aug 18

⌛ Last-Minute

SFO - Guayaquil

San Francisco (SFO) - Guayaquil (GYE)

Frontier Airlines

$659

$625

One-way

Biggest price drops on these dates for flights from San Francisco to Guayaquil

3 nights

Jul 27 - Jul 30

$953 → $650

32%

2 nights

Jul 27 - Jul 29

$951 → $650

32%

3 nights

Jul 26 - Jul 29

$953 → $754

21%

4 nights

Jul 26 - Jul 30

$947 → $754

20%

Popular Airports to fly from San Francisco to Guayaquil