How many flights from Medellín to Guayaquil are non-stop?

In the trailing 90 days, approximately 15.6% of flights from Medellín to Guayaquil were non-stop. For flights that included a stopover, the median number of stopovers was one. This indicates that while direct options are available, connecting flights are more common for this route.

How many hours is the flight from Medellín to Guayaquil?

A direct flight from Medellín to Guayaquil typically takes 2 hours and 0 minutes. This route covers a distance of 1050 kilometers. For flights with one stop, the median duration increases to 4 hours and 55 minutes, reflecting the additional time for layovers.

How much more do direct flights from Medellín to Guayaquil cost?

Historically, direct flights from Medellín to Guayaquil have been more expensive than connecting flights. On average, direct flights cost 54% more than connecting options. The median price for a direct flight was $380, while connecting flights had a median price of $247. Direct flights accounted for approximately 13.9% of the available options in the trailing 90 days.

Flights From Medellín

To Guayaquil

Cheap Flights from Medellín to Guayaquil

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Medellín

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Fares are subject to change and may not be available for all dates. (Data last updated Sep 14, 2026.)

Today’s best flight deals from Medellín to Guayaquil

Explore current cheapest deals departing from Medellín to Guayaquil

2026-10-21 – 2026-10-26
MDE - Guayaquil
43% AI deal score
$290
$351
Round trip
2026-10-09 – 2026-10-12
MDE - Guayaquil
40% AI deal score
$181
$363
Round trip
2027-02-17 – 2027-02-21
MDE - Guayaquil
39% AI deal score
$233
$366
Round trip
2026-10-16 – 2026-10-20
MDE - Guayaquil
42% AI deal score
$294
$367
Round trip
2026-10-10 – 2026-10-14
MDE - Guayaquil
42% AI deal score
$294
$368
Round trip
2026-09-23 – 2026-09-26
MDE - Guayaquil
47% AI deal score
$426
$369
Round trip
2026-10-28 – 2026-11-02
MDE - Guayaquil
37% AI deal score
$290
$369
Round trip
2026-10-29 – 2026-11-05
MDE - Guayaquil
37% AI deal score
$282
$369
Round trip
2026-10-30 – 2026-11-02
MDE - Guayaquil
37% AI deal score
$294
$369
Round trip
2026-10-30 – 2026-11-03
MDE - Guayaquil
37% AI deal score
$293
$369
Round trip

Medellín to Guayaquil: Overview

Insights for flights from Medellín to Guayaquil

Right now, fares for flights from Medellín to Guayaquil are above the typical level. Over a 90-day period, prices typically range from $234–$335, with a median of $247. There are currently no recent fares classified as a good price for this route.

A typical journey from Medellín to Guayaquil takes 4h 55m, including connections. Most itineraries for cheap flights from Medellín to Guayaquil connect at least once, with a median of 1 stopover when not flying direct. Only 15.6% of recent fares were for non-stop flights.

The cheapest time to fly from Medellín to Guayaquil is typically in June, with a median fare of $245. Other affordable months include July and May, both with median fares of $246. New deals for this route appear almost daily, offering frequent opportunities to find competitive prices.

The route from Medellín to Guayaquil covers a distance of 1,050 km, classifying it as a short-haul flight. This distance means you can expect a relatively quick journey, even with potential connections.

How much is a round trip from Medellín to Guayaquil

Regular price: $115 - $333

Prices for flights from Medellín to Guayaquil are currently above the regular range.

Regular prices for flights from Medellín to Guayaquil typically range from $115 to $333. The current lowest deal is $366 with Avianca, for travel from Oct 14-Nov 11.

now $366

Low $115

High $333

The cheapest time to fly from Medellín to Guayaquil

The cheapest month to fly from MDE to GYE is June, with a median price of $245. The most expensive month is August, with a median price of $370. Prices are generally lower from March to November.

June

Cheapest

Flights from $245

August

Most Expensive

Flights from $370

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Medellín to Guayaquil

Avianca

Last-minute flights going from Medellín to Guayaquil

Tue, Sep 15

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

$442

$392

One-way

Fri, Sep 18

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$516

$366

One-way

Fri, Sep 18

⌛ Last-Minute

EOH - Guayaquil

Medellín (EOH) - Guayaquil (GYE)

EUjet

$357

$613

One-way

Sun, Sep 20

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

LATAM Chile

$427

$437

One-way

Mon, Sep 21

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$263

$379

One-way

Mon, Sep 21

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$463

$438

One-way

Biggest price drops on these dates for flights from Medellín to Guayaquil

1 night

Sep 18 - Sep 19

$516 → $366

29%

4 nights

Sep 17 - Sep 21

$507 → $369

27%

1 night

Sep 15 - Sep 16

$524 → $389

26%

2 nights

Sep 14 - Sep 16

$523 → $455

13%

Popular Airports to fly from Medellín to Guayaquil

Medellín - Guayaquil route insights

💸 Price insights

Recent fares are above the typical level

Recent fares for Medellín to Guayaquil are above the typical level for this route.

📅 Best time to fly

Fly in June, July, or May for the best prices

Historically, June ($245), July ($246), and May ($246) offer the lowest median prices.

⏱️ Flight duration

Expect a median flight time of 4h 55m

Flights from Medellín to Guayaquil typically have a median duration of 4 hours and 55 minutes.

✈️ Airlines & availability

Connecting flights are more common

Only 15.6% of recent flights are direct, with connecting routes typically having 1 stopover.

🏆 Airline highlight

Avianca offers direct flights

Avianca is an airline that has offered direct flights on the Medellín to Guayaquil route.

🎯 Booking tip

Deals appear frequently on this route

Deals for flights from Medellín to Guayaquil have historically appeared with frequent cadence.

Medellín main airports to depart from

José María Córdova International (MDE)

Cheapest

José María Córdova International Airport is a key departure point for flights from Medellín to Guayaquil.

📍 ~20 km from Medellín (reachable by car)

💸 Flights from ~$358

Guayaquil main airports to arrive at

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International Airport is a great arrival choice for your trip to Guayaquil.

📍 ~5 km from city center (reachable by car)

💸 Flights from ~$353

Airports nearby Guayaquil used as alternative

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International is Ecuador's primary international hub, offering extensive routes and frequent connections to Guayaquil.

📍 ~270 km from Guayaquil (significant road travel time, approx. 7-8 hours, if not flying between cities)

💸 Flights from ~$309

Business & First Class Flight Deals to Guayaquil

$1,006

Save $451

LATAM Chile

Business Class

Frequently Asked Questions About Flights to Guayaquil

Historically, the optimal booking window for flights from Medellín to Guayaquil is typically 14-27 days before departure. Within this period, the average price observed was $255. Booking too far in advance, such as 60+ days out, typically saw average prices around $310. Conversely, booking within 0-6 days of departure also showed higher average prices, at approximately $261.

Across the trailing quarter, a good price for a flight from Medellín to Guayaquil was considered to be $234 or less. The median price for this route was $247. Prices tended to increase significantly for fares above the median, with 75% of prices observed being $335 or less.

Historically, the months of June, July, and May have shown the cheapest flights from Medellín to Guayaquil, with median prices around $245 to $246. The annual median price for this route is $247. While July is listed among the cheapest, it also represents the most expensive month when considering the overall historical data.

Related routes

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Flights to Guayaquil from other cities

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Medellín to Guayaquil: Overview

Insights for flights from Medellín to Guayaquil

How much is a round trip from Medellín to Guayaquil

Regular price: $115 - $333

Prices for flights from Medellín to Guayaquil are currently above the regular range.

Regular prices for flights from Medellín to Guayaquil typically range from $115 to $333. The current lowest deal is $366 with Avianca, for travel from Oct 14-Nov 11.

now $366

Low $115

High $333

The cheapest time to fly from Medellín to Guayaquil

The cheapest month to fly from MDE to GYE is June, with a median price of $245. The most expensive month is August, with a median price of $370. Prices are generally lower from March to November.

June

Cheapest

Flights from $245

August

Most Expensive

Flights from $370

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Medellín to Guayaquil

Avianca

Last-minute flights going from Medellín to Guayaquil

Tue, Sep 15

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

$442

$392

One-way

Fri, Sep 18

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$516

$366

One-way

Fri, Sep 18

⌛ Last-Minute

EOH - Guayaquil

Medellín (EOH) - Guayaquil (GYE)

EUjet

$357

$613

One-way

Sun, Sep 20

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

LATAM Chile

$427

$437

One-way

Mon, Sep 21

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$263

$379

One-way

Mon, Sep 21

⌛ Last-Minute

MDE - Guayaquil

Medellín (MDE) - Guayaquil (GYE)

Avianca

$463

$438

One-way

Biggest price drops on these dates for flights from Medellín to Guayaquil

1 night

Sep 18 - Sep 19

$516 → $366

29%

4 nights

Sep 17 - Sep 21

$507 → $369

27%

1 night

Sep 15 - Sep 16

$524 → $389

26%

2 nights

Sep 14 - Sep 16

$523 → $455

13%

Popular Airports to fly from Medellín to Guayaquil