Are direct flights from Des Moines to Rome always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers, but they are not always the most budget-friendly choice. Flights with one or more connections can often be less expensive. Consider your priorities for cost versus travel duration.

Can flexible travel dates help on Des Moines to Rome flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Mid-week flights or traveling during off-peak seasons often present lower fares compared to weekends or popular holiday periods. Adjusting your departure or return by a few days may yield savings.

What extra costs should I check before booking Des Moines to Rome flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Des Moines

To Rome

Cheap Flights from Des Moines to Rome

Browse current best options from Des Moines. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Des Moines

RatePunk searches hundreds of travel sites at once for deals on flights to Rome

Prices updated 7 days ago

482 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)

Today’s best flight deals from Des Moines to Rome

Explore current cheapest deals departing from Des Moines to Rome

2026-11-18 – 2026-11-26
DSM - Rome
80% AI deal score
$760
$714
Round trip
2026-12-11 – 2026-12-18
DSM - Rome
81% AI deal score
$812
$724
Round trip
2026-12-10 – 2026-12-17
DSM - Rome
81% AI deal score
$812
$733
Round trip
2026-12-05 – 2026-12-13
DSM - Rome
78% AI deal score
$785
$737
Round trip
2026-11-09 – 2026-11-19
DSM - Rome
75% AI deal score
$765
$758
Round trip
2026-11-09 – 2026-12-03
DSM - Rome
74% AI deal score
$746
$767
Round trip
2026-11-16 – 2026-11-19
DSM - Rome
77% AI deal score
$833
$775
Round trip
2026-11-16 – 2026-12-03
DSM - Rome
74% AI deal score
$735
$784
Round trip
2026-11-09 – 2026-11-12
DSM - Rome
77% AI deal score
$881
$823
Round trip
2026-11-23 – 2026-12-03
DSM - Rome
74% AI deal score
$749
$870
Round trip

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

For flights from Des Moines to Rome, fares typically range from $795–$1723, with a median of $1176. Right now, fares are below the typical level, and about 12% of recent fares were classified as a good price. New deals for this route show up several times a week, suggesting a regular cadence of price fluctuations.

When is the cheapest time to fly from Des Moines to Rome? The data indicates that February is typically the most affordable month, with a median fare of $774. Following closely, January also offers competitive prices, with a median of $779. Travelers can also find relatively lower fares in August, where the median price is around $867.

A typical journey from Des Moines to Rome takes about 13h 1m, including connections. This is a long-haul route, covering a substantial distance of 8139 kilometers. Since there are no direct flights from Des Moines to Rome, most itineraries connect at least once, with the median number of stopovers being 3.

How much is a round trip from Des Moines to Rome

Regular price: $648 - $1,631

Prices for flights from Des Moines to Rome are currently within the regular range.

The regular price range for flights from Des Moines to Rome is between $648 and $1631. The current lowest deal is $751 with Air Canada, for travel from Dec 5-Dec 13.

now $751

Low $648

High $1,631

The cheapest time to fly from Des Moines to Rome

The cheapest month to fly from Des Moines to Rome is February, with a median price of $774. The most expensive month is December, with a median price of $1751. Prices are generally lower from January to November.

February

Cheapest

Flights from $774

December

Most Expensive

Flights from $1,751

Jan

Feb

Jun

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to Rome

United Airlines

Allegiant Air

TAP Portugal

Icelandair

Last-minute flights going from Des Moines to Rome

Sun, Nov 8

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Aer Lingus

$758

$981

One-way

Sun, Nov 8

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Aer Lingus

$778

$986

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$765

$751

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$771

$756

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$746

$774

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$881

$826

One-way

Biggest price drops on these dates for flights from Des Moines to Rome

7 nights

Apr 7 - Apr 14

$1,052 → $937

11%

7 nights

Dec 3 - Dec 10

$812 → $717

12%

7 nights

Dec 7 - Dec 14

$812 → $720

11%

7 nights

Dec 1 - Dec 8

$812 → $728

10%

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

💸 Price insights

Recent fares are below the typical level.

Recent fares from Des Moines to Rome are below the typical level of $1176.

📅 Best time to fly

Fly in February for the best prices.

Historically, February has offered the lowest median price at $774 for Des Moines to Rome.

⏱️ Flight duration

Connecting flights take 13h 1m.

The typical connecting flight from Des Moines to Rome has a median duration of 13h 1m.

✈️ Airlines & availability

Connecting flights are dominant for this route.

This route primarily features connecting flights, with 0% direct flights historically available.

🏆 Airline highlight

Air Canada offers a recent deal.

A recent deal from Des Moines to Rome was found on Air Canada for $751 via skyscanner.

🎯 Booking tip

Deals appear regularly.

Deals for flights from Des Moines to Rome are classified as appearing regularly.

Des Moines main airports to depart from

Des Moines International (DSM)

Cheapest

Des Moines International is a convenient option for flights from Des Moines to Rome.

📍 ~8 km from Des Moines city center (reachable by car)

💸 Flights from ~$745

Rome main airports to arrive at

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient arrival choice for flights from Des Moines to Rome.

📍 ~24 km from Rome city center (reachable by car, bus, or train).

💸 Flights from ~$754

Airports nearby Rome used as alternative

Naples International (NAP)

Naples International is a major international hub with significant capacity for long-haul and European routes.

📍 ~187 km from Rome (reachable by high-speed rail)

💸 Flights from ~$857

Business & First Class Flight Deals to Rome

Discover luxury on the budget with premium cabin class on flights from Des Moines to Rome.

Elite

Best Elite deals to Rome

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From DSM

Elite

Nov 30

Rome, Italy

94% AI deal score

$7,009

$3,683

Save $3,326

Aer Lingus

Business Class

From DSM

Elite

Nov 26

Rome, Italy

94% AI deal score

$7,009

$3,794

Save $3,215

Iberia Airlines

Business Class

From DSM

Elite

Dec 17

Rome, Italy

91% AI deal score

$7,237

$4,655

Save $2,582

Aer Lingus

Business Class

From DSM

Elite

Dec 23

Rome, Italy

89% AI deal score

$7,321

$4,636

Save $2,685

From DSM

Elite

Dec 24

Rome, Italy

89% AI deal score

$7,314

$4,636

Save $2,678

From DSM

Elite

Jan 01

Rome, Italy

86% AI deal score

$6,202

$4,745

Save $1,457

From DSM

Elite

Dec 22

Rome, Italy

85% AI deal score

$7,359

$5,345

Save $2,014

From DSM

Elite

Jan 09

Rome, Italy

81% AI deal score

$6,216

$5,340

Save $876

Aer Lingus

Business Class

From DSM

Elite

Dec 12

Rome, Italy

81% AI deal score

$7,295

$5,998

Save $1,297

Aer Lingus

Business Class

From DSM

Elite

Dec 22

Rome, Italy

80% AI deal score

$7,320

$5,410

Save $1,910

From DSM

Elite

Jan 18

Rome, Italy

80% AI deal score

$6,285

$5,605

Save $680

Aer Lingus

Business Class

From DSM

Elite

Jan 16

Rome, Italy

78% AI deal score

$6,290

$5,345

Save $945

Frequently Asked Questions About Flights to Rome

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can also help you identify better deals. Setting up price alerts may notify you when fares drop for your desired route.

Booking flights in advance, often several months before your intended departure, may lead to better prices. However, last-minute deals can sometimes appear, so it's wise to monitor fare trends. Prices can fluctuate, so there isn't one single best time to book.

Comparing nearby airports at both your origin and destination can sometimes uncover more economical flight options. While it may add to your travel time, the potential savings on airfare can be significant. Always factor in the cost and convenience of ground transportation.

Related routes

More routes from Des Moines

Flights from Des Moines to Amsterdam Flights from Des Moines to Athens Flights from Des Moines to Bangkok Flights from Des Moines to Beijing Flights from Des Moines to Chicago Flights from Des Moines to Copenhagen Flights from Des Moines to Denver Flights from Des Moines to San Antonio Flights from Des Moines to Seattle Flights from Des Moines to Syracuse Flights from Des Moines to Toronto Flights from Des Moines to Zürich

Flights to Rome from other cities

Flights from Basel to Rome Flights from Bergerac to Rome Flights from Detroit to Rome Flights from Donostia / San Sebastián to Rome Flights from Dortmund to Rome Flights from Dubai to Rome Flights from Dublin to Rome Flights from Düsseldorf to Rome Flights from Edinburgh to Rome Flights from Eindhoven to Rome Flights from Panama City to Rome Flights from Vail to Rome

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

How much is a round trip from Des Moines to Rome

Regular price: $648 - $1,631

Prices for flights from Des Moines to Rome are currently within the regular range.

The regular price range for flights from Des Moines to Rome is between $648 and $1631. The current lowest deal is $751 with Air Canada, for travel from Dec 5-Dec 13.

now $751

Low $648

High $1,631

The cheapest time to fly from Des Moines to Rome

February

Cheapest

Flights from $774

December

Most Expensive

Flights from $1,751

Jan

Feb

Jun

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to Rome

United Airlines

Allegiant Air

TAP Portugal

Icelandair

Last-minute flights going from Des Moines to Rome

Sun, Nov 8

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Aer Lingus

$758

$981

One-way

Sun, Nov 8

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Aer Lingus

$778

$986

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$765

$751

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$771

$756

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$746

$774

One-way

Mon, Nov 9

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

Allegiant Air, TAP Portugal

$881

$826

One-way

Biggest price drops on these dates for flights from Des Moines to Rome

7 nights

Apr 7 - Apr 14

$1,052 → $937

11%

7 nights

Dec 3 - Dec 10

$812 → $717

12%

7 nights

Dec 7 - Dec 14

$812 → $720

11%

7 nights

Dec 1 - Dec 8

$812 → $728

10%

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

💸 Price insights

Recent fares are below the typical level.

Recent fares from Des Moines to Rome are below the typical level of $1176.

📅 Best time to fly

Fly in February for the best prices.

Historically, February has offered the lowest median price at $774 for Des Moines to Rome.

⏱️ Flight duration

Connecting flights take 13h 1m.

The typical connecting flight from Des Moines to Rome has a median duration of 13h 1m.

✈️ Airlines & availability

Connecting flights are dominant for this route.

This route primarily features connecting flights, with 0% direct flights historically available.

🏆 Airline highlight

Air Canada offers a recent deal.

A recent deal from Des Moines to Rome was found on Air Canada for $751 via skyscanner.

🎯 Booking tip

Deals appear regularly.

Deals for flights from Des Moines to Rome are classified as appearing regularly.

Des Moines main airports to depart from

Des Moines International (DSM)

Cheapest

Des Moines International is a convenient option for flights from Des Moines to Rome.

📍 ~8 km from Des Moines city center (reachable by car)

💸 Flights from ~$745

Rome main airports to arrive at

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient arrival choice for flights from Des Moines to Rome.

📍 ~24 km from Rome city center (reachable by car, bus, or train).

💸 Flights from ~$754

Airports nearby Rome used as alternative

Naples International (NAP)

Naples International is a major international hub with significant capacity for long-haul and European routes.

📍 ~187 km from Rome (reachable by high-speed rail)

💸 Flights from ~$857

Business & First Class Flight Deals to Rome

Discover luxury on the budget with premium cabin class on flights from Des Moines to Rome.

Elite

Best Elite deals to Rome

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From DSM

Elite

Nov 30

Rome, Italy

94% AI deal score

$7,009

$3,683

Save $3,326

Aer Lingus

Business Class

From DSM

Elite

Nov 26

Rome, Italy

94% AI deal score

$7,009

$3,794

Save $3,215

Iberia Airlines

Business Class

From DSM

Elite

Dec 17

Rome, Italy

91% AI deal score

$7,237

$4,655

Save $2,582

Aer Lingus

Business Class

From DSM

Elite

Dec 23

Rome, Italy

89% AI deal score

$7,321

$4,636

Save $2,685

From DSM

Elite

Dec 24

Rome, Italy

89% AI deal score

$7,314

$4,636

Save $2,678

From DSM

Elite

Jan 01

Rome, Italy

86% AI deal score

$6,202

$4,745

Save $1,457

From DSM

Elite

Dec 22

Rome, Italy

85% AI deal score

$7,359

$5,345

Save $2,014

From DSM

Elite

Jan 09

Rome, Italy

81% AI deal score

$6,216

$5,340

Save $876

Aer Lingus

Business Class

From DSM

Elite

Dec 12

Rome, Italy

81% AI deal score

$7,295

$5,998

Save $1,297

Aer Lingus

Business Class

From DSM

Elite

Dec 22

Rome, Italy

80% AI deal score

$7,320

$5,410

Save $1,910

From DSM

Elite

Jan 18

Rome, Italy

80% AI deal score

$6,285

$5,605

Save $680

Aer Lingus

Business Class

From DSM

Elite

Jan 16

Rome, Italy

78% AI deal score

$6,290

$5,345

Save $945

Frequently Asked Questions About Flights to Rome

Cheap Flights from Des Moines to Rome

Today’s best flight deals from Des Moines to Rome

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

How much is a round trip from Des Moines to Rome

The cheapest time to fly from Des Moines to Rome

Direct flights from Des Moines to Rome

Last-minute flights going from Des Moines to Rome

Biggest price drops on these dates for flights from Des Moines to Rome

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

Recent fares are below the typical level.

Fly in February for the best prices.

Connecting flights take 13h 1m.

Connecting flights are dominant for this route.

Air Canada offers a recent deal.

Deals appear regularly.

Des Moines main airports to depart from

Rome main airports to arrive at

Airports nearby Rome used as alternative

Business & First Class Flight Deals to Rome

Best Elite deals to Rome

Nov 30

Nov 26

Dec 17

Dec 23

Dec 24

Jan 01

Dec 22

Jan 09

Dec 12

Dec 22

Jan 18

Jan 16

Frequently Asked Questions About Flights to Rome

How can I find cheap flights from Des Moines to Rome?

When should I book flights from Des Moines to Rome?

Should I compare nearby airports for flights from Des Moines to Rome?

Are direct flights from Des Moines to Rome always the best option?

Can flexible travel dates help on Des Moines to Rome flights?

What extra costs should I check before booking Des Moines to Rome flights?

Related routes

More routes from Des Moines

Flights to Rome from other cities

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

How much is a round trip from Des Moines to Rome

The cheapest time to fly from Des Moines to Rome

Direct flights from Des Moines to Rome

Last-minute flights going from Des Moines to Rome

Biggest price drops on these dates for flights from Des Moines to Rome

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

Recent fares are below the typical level.

Fly in February for the best prices.

Connecting flights take 13h 1m.

Connecting flights are dominant for this route.

Air Canada offers a recent deal.

Deals appear regularly.

Des Moines main airports to depart from

Rome main airports to arrive at

Airports nearby Rome used as alternative

Business & First Class Flight Deals to Rome

Best Elite deals to Rome

Nov 30

Nov 26

Dec 17

Dec 23

Dec 24

Jan 01

Dec 22

Jan 09

Dec 12

Dec 22

Jan 18

Jan 16

Frequently Asked Questions About Flights to Rome

How can I find cheap flights from Des Moines to Rome?

When should I book flights from Des Moines to Rome?

Should I compare nearby airports for flights from Des Moines to Rome?