Are direct flights from Des Moines to Rome always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, they are not always the most budget-friendly choice. Flights with one or more connections can often be cheaper, so it's worth comparing.

Can flexible travel dates help on Des Moines to Rome flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying on weekdays or during off-peak seasons usually results in lower fares compared to weekends or major holidays. Adjusting your departure or return by a few days may reveal better deals.

What extra costs should I check before booking Des Moines to Rome flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget.

Flights From Des Moines

To Rome

Cheap Flights from Des Moines to Rome

Browse current best options from Des Moines. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Des Moines

RatePunk searches hundreds of travel sites at once for deals on flights to Rome

Prices updated today

462 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 15, 2026.)

Today’s best flight deals from Des Moines to Rome

Explore current cheapest deals departing from Des Moines to Rome

2026-11-11 – 2026-11-18
DSM - Rome
90% AI deal score
$776
$586
Round trip
2026-10-25 – 2026-11-10
DSM - Rome
88% AI deal score
$820
$587
Round trip
2026-11-08 – 2026-11-17
DSM - Rome
85% AI deal score
$755
$601
Round trip
2027-01-12 – 2027-01-20
DSM - Rome
85% AI deal score
$754
$601
Round trip
2027-01-12 – 2027-01-21
DSM - Rome
85% AI deal score
$749
$601
Round trip
2027-01-12 – 2027-01-22
DSM - Rome
80% AI deal score
$744
$601
Round trip
2027-01-12 – 2027-01-26
DSM - Rome
85% AI deal score
$746
$601
Round trip
2027-01-10 – 2027-01-20
DSM - Rome
80% AI deal score
$744
$607
Round trip
2027-01-10 – 2027-01-21
DSM - Rome
80% AI deal score
$742
$607
Round trip
2027-01-10 – 2027-01-22
DSM - Rome
80% AI deal score
$743
$607
Round trip

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

Flights from Des Moines to Rome typically range from $800 to $1365, with a median fare of $1020. Right now, fares for this route are near the typical level. Finding cheap flights from Des Moines to Rome can be challenging, as currently 0% of recent fares were classified as a good price.

If you are looking for the cheapest time to fly from Des Moines to Rome, consider traveling in January, when the median fare is $658. Other affordable months include March, with a median fare of $669, and April, where the median fare is $674.

A typical journey from Des Moines to Rome takes about 45h 2m, including connections. This is a long-haul route, covering a distance of 8139 km. Given that most itineraries connect at least once, the overall travel time reflects the need for layovers.

For flights from Des Moines to Rome, most itineraries connect at least once. There are no direct flights from Des Moines to Rome, as 0% of recent fares were non-stop. When connecting, the median number of stopovers is 2.

How much is a round trip from Des Moines to Rome

Regular price: $653 - $1,588

Prices are currently below the regular range for flights from Des Moines to Rome.

The regular price range for flights from Des Moines to Rome is between $653 and $1588. The current lowest deal is $596 with KLM, for travel from Nov 11-Nov 18.

now $596

Low $653

High $1,588

The cheapest time to fly from Des Moines to Rome

The cheapest month to fly from Des Moines to Rome is January, with a median price of $658. The most expensive month is June, with a median price of $2487. Prices are generally lower from January to September.

January

Cheapest

Flights from $658

June

Most Expensive

Flights from $2,487

Jan

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to Rome

United Airlines

Allegiant Air

Icelandair

Air Canada

Last-minute flights going from Des Moines to Rome

Sun, Sep 20

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$911

$695

One-way

Mon, Sep 21

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$921

$695

One-way

Wed, Sep 23

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

United Airlines

$948

$787

One-way

Fri, Sep 25

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

United Airlines

$956

$902

One-way

Mon, Sep 28

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$896

$695

One-way

Tue, Sep 29

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$916

$755

One-way

Biggest price drops on these dates for flights from Des Moines to Rome

7 nights

Mar 15 - Mar 22

$1,135 → $806

29%

11 nights

Mar 29 - Apr 9

$1,159 → $909

22%

8 nights

Mar 1 - Mar 9

$967 → $767

21%

7 nights

Oct 15 - Oct 22

$1,045 → $861

18%

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Des Moines to Rome are $596, which is below the typical level.

📅 Best time to fly

January, March, and April are cheapest

Historically, January ($658), March ($669), and April ($674) offer the lowest median prices.

⏱️ Flight duration

Long-haul flights average 45h 2m

Flights from Des Moines to Rome are long-haul, with a median duration of 45 hours 2 minutes.

✈️ Airlines & availability

Connecting flights are dominant

This route is connecting dominant, with a median of 2 stopovers on connecting flights.

🏆 Airline highlight

KLM offers a recent deal

KLM recently offered a deal for $596 from Des Moines to Rome via kiwi for November 11-18.

🎯 Booking tip

Deals are frequent on this route

Deals for flights from Des Moines to Rome are classified as frequent, appearing often.

Des Moines main airports to depart from

Des Moines International (DSM)

Cheapest

Des Moines International is a good choice for flights from Des Moines to Rome.

📍 ~8 km from Des Moines (reachable by car)

💸 Flights from ~$728

Rome main airports to arrive at

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient option for flights from Des Moines to Rome.

📍 ~24 km from Rome city center (reachable by car, train, or bus).

💸 Flights from ~$728

Airports nearby Rome used as alternative

Naples International (NAP)

Cheapest

Rome, Italy

91% AI deal score

$7,252

$4,854

Save $2,398

United Airlines

Business Class

From DSM

Elite

Nov 13

Rome, Italy

91% AI deal score

$2,631

$1,862

Save $769

United Airlines

Business Class

From DSM

Elite

Oct 12

Rome, Italy

81% AI deal score

$7,830

$6,554

Save $1,276

Aeroméxico, +1

Business Class

From DSM

Elite

Oct 12

Rome, Italy

81% AI deal score

$7,946

$6,554

Save $1,392

Aeroméxico, +1

Business Class

From DSM

Elite

Oct 12

Rome, Italy

81% AI deal score

$7,864

$6,554

Save $1,310

Aeroméxico, +1

Business Class

From DSM

Elite

Oct 12

Rome, Italy

81% AI deal score

$7,946

$6,554

Save $1,392

Aeroméxico, +1

Business Class

From DSM

Elite

Oct 12

Rome, Italy

81% AI deal score

$7,946

$6,554

Save $1,392

Aeroméxico, +1

Business Class

From DSM

Elite

Oct 12

Rome, Italy

81% AI deal score

$7,946

$6,671

Save $1,275

Aeroméxico, +1

Business Class

From DSM

Elite

Oct 29

Rome, Italy

81% AI deal score

$8,295

$7,162

Save $1,133

Alaska Airlines, Inc., +1

Business Class

From DSM

Elite

Oct 30

Rome, Italy

81% AI deal score

$8,424

$7,162

Save $1,262

Alaska Airlines, Inc., +1

Business Class

From DSM

Elite

Oct 12

Rome, Italy

80% AI deal score

$7,946

$6,827

Save $1,119

Aeroméxico, +1

Business Class

Frequently Asked Questions About Flights to Rome

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking flights in advance, often several months ahead, may help secure better prices. However, prices can fluctuate, so monitoring fares is usually a good strategy. Last-minute deals are less common for international routes.

Comparing nearby airports at both your origin and destination can sometimes lead to more affordable flight options. While it may add to travel time, the savings on airfare can be significant. Always factor in ground transportation costs and convenience.

Related routes

More routes from Des Moines

Flights from Des Moines to Amsterdam Flights from Des Moines to Athens Flights from Des Moines to Bangkok Flights from Des Moines to Beijing Flights from Des Moines to Chicago Flights from Des Moines to Copenhagen Flights from Des Moines to Denver Flights from Des Moines to San Antonio Flights from Des Moines to Seattle Flights from Des Moines to Syracuse Flights from Des Moines to Toronto Flights from Des Moines to Zürich

Flights to Rome from other cities

Flights from Basel to Rome Flights from Bergerac to Rome Flights from Detroit to Rome Flights from Donostia / San Sebastián to Rome Flights from Dortmund to Rome Flights from Dubai to Rome Flights from Dublin to Rome Flights from Düsseldorf to Rome Flights from Edinburgh to Rome Flights from Eindhoven to Rome Flights from Panama City to Rome Flights from Vail to Rome

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

How much is a round trip from Des Moines to Rome

Regular price: $653 - $1,588

Prices are currently below the regular range for flights from Des Moines to Rome.

The regular price range for flights from Des Moines to Rome is between $653 and $1588. The current lowest deal is $596 with KLM, for travel from Nov 11-Nov 18.

now $596

Low $653

High $1,588

The cheapest time to fly from Des Moines to Rome

January

Cheapest

Flights from $658

June

Most Expensive

Flights from $2,487

Jan

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Des Moines to Rome

United Airlines

Allegiant Air

Icelandair

Air Canada

Last-minute flights going from Des Moines to Rome

Sun, Sep 20

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$911

$695

One-way

Mon, Sep 21

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$921

$695

One-way

Wed, Sep 23

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

United Airlines

$948

$787

One-way

Fri, Sep 25

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

United Airlines

$956

$902

One-way

Mon, Sep 28

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$896

$695

One-way

Tue, Sep 29

⌛ Last-Minute

DSM - Rome

Des Moines (DSM) - Rome (FCO)

$916

$755

One-way

Biggest price drops on these dates for flights from Des Moines to Rome

7 nights

Mar 15 - Mar 22

$1,135 → $806

29%

11 nights

Mar 29 - Apr 9

$1,159 → $909

22%

8 nights

Mar 1 - Mar 9

$967 → $767

21%

7 nights

Oct 15 - Oct 22

$1,045 → $861

18%

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Des Moines to Rome are $596, which is below the typical level.

📅 Best time to fly

January, March, and April are cheapest

Historically, January ($658), March ($669), and April ($674) offer the lowest median prices.

⏱️ Flight duration

Long-haul flights average 45h 2m

Flights from Des Moines to Rome are long-haul, with a median duration of 45 hours 2 minutes.

✈️ Airlines & availability

Connecting flights are dominant

This route is connecting dominant, with a median of 2 stopovers on connecting flights.

🏆 Airline highlight

KLM offers a recent deal

KLM recently offered a deal for $596 from Des Moines to Rome via kiwi for November 11-18.

🎯 Booking tip

Deals are frequent on this route

Deals for flights from Des Moines to Rome are classified as frequent, appearing often.

Des Moines main airports to depart from

Des Moines International (DSM)

Cheapest

Des Moines International is a good choice for flights from Des Moines to Rome.

📍 ~8 km from Des Moines (reachable by car)

💸 Flights from ~$728

Rome main airports to arrive at

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a convenient option for flights from Des Moines to Rome.

📍 ~24 km from Rome city center (reachable by car, train, or bus).

💸 Flights from ~$728

Airports nearby Rome used as alternative

Naples International (NAP)

Cheapest

Naples International is a major international hub with significant capacity for long-haul and European routes.

Rome, Italy

80% AI deal score

$7,946

$6,827

Save $1,119

Aeroméxico, +1

Business Class

Frequently Asked Questions About Flights to Rome

Cheap Flights from Des Moines to Rome

Today’s best flight deals from Des Moines to Rome

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

How much is a round trip from Des Moines to Rome

The cheapest time to fly from Des Moines to Rome

Direct flights from Des Moines to Rome

Last-minute flights going from Des Moines to Rome

Biggest price drops on these dates for flights from Des Moines to Rome

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

Recent fares are below the typical level

January, March, and April are cheapest

Long-haul flights average 45h 2m

Connecting flights are dominant

KLM offers a recent deal

Deals are frequent on this route

Des Moines main airports to depart from

Rome main airports to arrive at

Airports nearby Rome used as alternative

Business & First Class Flight Deals to Rome

Best Elite deals to Rome

Dec 06

Nov 22

Nov 13

Oct 12

Oct 12

Oct 12

Oct 12

Oct 12

Oct 12

Oct 29

Oct 30

Oct 12

Frequently Asked Questions About Flights to Rome

How can I find cheap flights from Des Moines to Rome?

When should I book flights from Des Moines to Rome?

Should I compare nearby airports for flights from Des Moines to Rome?

Are direct flights from Des Moines to Rome always the best option?

Can flexible travel dates help on Des Moines to Rome flights?

What extra costs should I check before booking Des Moines to Rome flights?

Related routes

More routes from Des Moines

Flights to Rome from other cities

Des Moines to Rome: Overview

Insights for flights from Des Moines to Rome

How much is a round trip from Des Moines to Rome

The cheapest time to fly from Des Moines to Rome

Direct flights from Des Moines to Rome

Last-minute flights going from Des Moines to Rome

Biggest price drops on these dates for flights from Des Moines to Rome

Popular Airports to fly from Des Moines to Rome

Des Moines - Rome route insights

Recent fares are below the typical level

January, March, and April are cheapest

Long-haul flights average 45h 2m

Connecting flights are dominant

KLM offers a recent deal

Deals are frequent on this route

Des Moines main airports to depart from

Rome main airports to arrive at

Airports nearby Rome used as alternative

Business & First Class Flight Deals to Rome

Best Elite deals to Rome

Dec 06

Nov 22

Nov 13

Oct 12

Oct 12

Oct 12

Oct 12

Oct 12

Oct 12

Oct 29

Oct 30

Oct 12

Frequently Asked Questions About Flights to Rome

How can I find cheap flights from Des Moines to Rome?

When should I book flights from Des Moines to Rome?

Should I compare nearby airports for flights from Des Moines to Rome?