Are direct flights from Florence to Knoxville always the best option?

Direct flights are often convenient and save time, but they are not always the cheapest option. Flights with layovers can sometimes be more affordable, especially for longer distances. Consider your budget and time constraints when making your choice.

Can flexible travel dates help on Florence to Knoxville flights?

Being flexible with your travel dates can significantly impact the price of your flight. Flying on weekdays or during off-peak seasons usually offers more competitive fares. Even shifting your departure or return by a day or two may result in savings.

What extra costs should I check before booking Florence to Knoxville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget.

Flights From Florence

To Knoxville

Cheap Flights from Florence to Knoxville

Browse current best options from Florence. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Florence

RatePunk searches hundreds of travel sites at once for deals on flights to Knoxville

Prices updated 1 day ago

461 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 14, 2026.)

Today’s best flight deals from Florence to Knoxville

Explore current cheapest deals departing from Florence to Knoxville

2026-10-14 – 2026-10-20
FLR - Knoxville
92% AI deal score
970 €
661 €
Round trip
2026-12-02 – 2026-12-11
FLR - Knoxville
86% AI deal score
1,024 €
779 €
Round trip
2026-12-09 – 2026-12-11
FLR - Knoxville
87% AI deal score
1,111 €
780 €
Round trip
2026-11-18 – 2026-12-04
FLR - Knoxville
76% AI deal score
860 €
783 €
Round trip
2026-12-02 – 2026-12-04
FLR - Knoxville
87% AI deal score
1,104 €
784 €
Round trip
2026-11-10 – 2026-12-04
FLR - Knoxville
76% AI deal score
855 €
787 €
Round trip
2026-11-03 – 2026-11-11
FLR - Knoxville
77% AI deal score
871 €
791 €
Round trip
2026-11-18 – 2026-12-11
FLR - Knoxville
76% AI deal score
859 €
792 €
Round trip
2026-10-21 – 2026-11-04
FLR - Knoxville
77% AI deal score
915 €
813 €
Round trip
2026-11-12 – 2026-12-04
FLR - Knoxville
75% AI deal score
855 €
818 €
Round trip

Florence to Knoxville: Overview

Insights for flights from Florence to Knoxville

For those looking for cheap flights from Florence to Knoxville, fares typically range from $1057–$1203, with a median of $1127. Right now, current fares are significantly below the typical level, with about 29% of recent fares classified as a good price. Deals are infrequent, so setting a price alert could be beneficial.

When considering the cheapest time to fly from Florence to Knoxville, April stands out with a median fare of $1104. Following closely, June offers a median fare of $1136, and May presents options with a median of $1149.

A typical journey from Florence to Knoxville takes approximately 56h 19m, including connections. Most itineraries on this route connect at least once, with the median number of stopovers for connecting flights being 2.

Flights from Florence to Knoxville cover a substantial distance of 7716 km, classifying this as a long-haul route. This means you can expect an extended travel experience across continents.

How much is a round trip from Florence to Knoxville

Regular price: €781 - €1,491

Prices are currently below the regular range.

The regular price range for flights from Florence to Knoxville is 781 EUR to 1491 EUR. The current lowest deal is 640 EUR with Vueling Airlines, for travel from Jan 20-Feb 5.

now 640 €

Low 781 €

High 1,491 €

The cheapest time to fly from Florence to Knoxville

The cheapest month to fly from Florence to Knoxville is April, with a median price of $1104. Prices are generally lower from April to June. The most expensive month is July, with a median price of $1338.

April

Cheapest

Flights from 1,104 €

July

Most Expensive

Flights from 1,338 €

Apr

May

Jun

Jul

Direct flights from Florence to Knoxville

Allegiant Air

Vueling Airlines

French Bee

Iberia Airlines

Last-minute flights going from Florence to Knoxville

Sun, Sep 27

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

KLM, Allegiant Air

1,104 €

1,908 €

One-way

Tue, Oct 6

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Vueling Airlines, Aer Lingus

1,032 €

1,691 €

One-way

Thu, Oct 8

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Alitalia, Allegiant Air

918 €

1,194 €

One-way

Wed, Oct 14

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Deutsche Luft Hansa

970 €

661 €

One-way

Tue, Oct 27

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Vueling Airlines, French Bee, Allegiant Air

928 €

912 €

One-way

Tue, Oct 27

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Vueling Airlines, French Bee, Allegiant Air

902 €

934 €

One-way

Biggest price drops on these dates for flights from Florence to Knoxville

2 nights

Dec 2 - Dec 4

1,107 € → 784 €

29%

6 nights

Oct 14 - Oct 20

970 € → 661 €

32%

16 nights

Jan 20 - Feb 5

898 € → 640 €

29%

19 nights

Jan 20 - Feb 8

897 € → 650 €

28%

Popular Airports to fly from Florence to Knoxville

Florence - Knoxville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Florence to Knoxville are below the typical level, with deals around $640.

📅 Best time to fly

April is historically the cheapest month

Historically, April is the cheapest month to fly from Florence to Knoxville, with a median price of $1104.

⏱️ Flight duration

Connecting flights average 56h 19m

Flights from Florence to Knoxville typically involve 2 stopovers, with an average duration of 56h 19m.

✈️ Airlines & availability

No direct flights available

There are no direct flights available from Florence to Knoxville; all routes include stopovers.

🏆 Airline highlight

Vueling Airlines offers a recent deal

Vueling Airlines recently offered a deal for $640 from Florence to Knoxville.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Florence to Knoxville are rare, so book when you see a good price.

Florence main airports to depart from

Florence (FLR)

Cheapest

Florence Airport is a convenient departure point for flights to Knoxville.

📍 ~6 km from Florence city center (reachable by car)

💸 Flights from ~€657

Knoxville main airports to arrive at

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport is a convenient arrival airport for your trip to Knoxville from Florence.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~€656

Airports nearby Knoxville used as alternative

Hartsfield–Jackson Atlanta International (ATL)

Cheapest

Consider Atlanta for unparalleled direct flight options and potential cost savings, despite the longer drive.

📍 ~250 km from Knoxville (reachable by car, ~3.5 to 4 hours drive)

💸 Flights from ~€544

Business & First Class Flight Deals to Knoxville

Discover luxury on the budget with premium cabin class on flights from Florence to Knoxville.

Elite

Best Elite deals to Knoxville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FLR

Elite

Oct 30

Knoxville, United States

74% AI deal score

$3,418

Iberia Airlines, +1

Business Class

From FLR

Elite

Sep 21

Knoxville, United States

74% AI deal score

$3,468

Iberia Airlines, +1

Business Class

From FLR

Elite

Nov 11

Knoxville, United States

73% AI deal score

$3,632

Iberia Airlines, +1

Business Class

From FLR

Elite

Sep 21

Knoxville, United States

73% AI deal score

$3,739

Iberia Airlines, +1

Business Class

From FLR

Elite

Dec 17

Knoxville, United States

72% AI deal score

$8,292

Air France, +1

Business Class

From FLR

Elite

Dec 26

Knoxville, United States

72% AI deal score

$8,292

Air France, +1

Business Class

From FLR

Elite

Dec 17

Knoxville, United States

72% AI deal score

$8,292

Air France, +1

Business Class

From FLR

Elite

Dec 18

Knoxville, United States

72% AI deal score

$8,292

Air France, +1

Business Class

From FLR

Elite

Dec 20

Knoxville, United States

72% AI deal score

$8,292

Air France, +1

Business Class

From FLR

Elite

Dec 18

Knoxville, United States

72% AI deal score

$8,292

Air France, +1

Business Class

From FLR

Elite

Dec 18

Knoxville, United States

72% AI deal score

$8,295

Air France, +1

Business Class

From FLR

Elite

Dec 20

Knoxville, United States

72% AI deal score

$8,295

Air France, +1

Business Class

Frequently Asked Questions About Flights to Knoxville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking flights in advance, often several months out, can sometimes lead to lower prices. However, prices can fluctuate, so monitoring fares over time may help you decide the optimal booking moment. Mid-week bookings are sometimes associated with better deals.

Comparing nearby airports at both your origin and destination can sometimes uncover more economical flight options. While it might add to your ground travel, the potential savings on airfare can be significant. Always factor in the total cost and travel time.

Related routes

More routes from Florence

Flights from Florence to Amsterdam Flights from Florence to Barcelona Flights from Florence to Bologna Flights from Florence to Boston Flights from Florence to Budapest Flights from Florence to Copenhagen Flights from Florence to Dayton Flights from Florence to Edinburgh Flights from Florence to Frankfurt Flights from Florence to Fuerteventura Flights from Florence to Venice Flights from Florence to Vienna

Flights to Knoxville from other cities

Flights from Atlanta to Knoxville Flights from Bangkok to Knoxville Flights from Chicago to Knoxville Flights from Hong Kong to Knoxville Flights from Houston to Knoxville Flights from Madrid to Knoxville Flights from Milan to Knoxville Flights from Nashville to Knoxville Flights from Rome to Knoxville Flights from San Francisco to Knoxville Flights from Southampton to Knoxville Flights from Venice to Knoxville

Florence to Knoxville: Overview

Insights for flights from Florence to Knoxville

Flights from Florence to Knoxville cover a substantial distance of 7716 km, classifying this as a long-haul route. This means you can expect an extended travel experience across continents.

How much is a round trip from Florence to Knoxville

Regular price: €781 - €1,491

Prices are currently below the regular range.

The regular price range for flights from Florence to Knoxville is 781 EUR to 1491 EUR. The current lowest deal is 640 EUR with Vueling Airlines, for travel from Jan 20-Feb 5.

now 640 €

Low 781 €

High 1,491 €

The cheapest time to fly from Florence to Knoxville

April

Cheapest

Flights from 1,104 €

July

Most Expensive

Flights from 1,338 €

Apr

May

Jun

Jul

Direct flights from Florence to Knoxville

Allegiant Air

Vueling Airlines

French Bee

Iberia Airlines

Last-minute flights going from Florence to Knoxville

Sun, Sep 27

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

KLM, Allegiant Air

1,104 €

1,908 €

One-way

Tue, Oct 6

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Vueling Airlines, Aer Lingus

1,032 €

1,691 €

One-way

Thu, Oct 8

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Alitalia, Allegiant Air

918 €

1,194 €

One-way

Wed, Oct 14

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Deutsche Luft Hansa

970 €

661 €

One-way

Tue, Oct 27

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Vueling Airlines, French Bee, Allegiant Air

928 €

912 €

One-way

Tue, Oct 27

⌛ Last-Minute

FLR - Knoxville

Florence (FLR) - Knoxville (TYS)

Vueling Airlines, French Bee, Allegiant Air

902 €

934 €

One-way

Biggest price drops on these dates for flights from Florence to Knoxville

2 nights

Dec 2 - Dec 4

1,107 € → 784 €

29%

6 nights

Oct 14 - Oct 20

970 € → 661 €

32%

16 nights

Jan 20 - Feb 5

898 € → 640 €

29%

19 nights

Jan 20 - Feb 8

897 € → 650 €

28%

Popular Airports to fly from Florence to Knoxville

Florence - Knoxville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Florence to Knoxville are below the typical level, with deals around $640.

📅 Best time to fly

April is historically the cheapest month

Historically, April is the cheapest month to fly from Florence to Knoxville, with a median price of $1104.

⏱️ Flight duration

Connecting flights average 56h 19m

Flights from Florence to Knoxville typically involve 2 stopovers, with an average duration of 56h 19m.

✈️ Airlines & availability

No direct flights available

There are no direct flights available from Florence to Knoxville; all routes include stopovers.

🏆 Airline highlight

Vueling Airlines offers a recent deal

Vueling Airlines recently offered a deal for $640 from Florence to Knoxville.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Florence to Knoxville are rare, so book when you see a good price.

Florence main airports to depart from

Florence (FLR)

Cheapest

Florence Airport is a convenient departure point for flights to Knoxville.

📍 ~6 km from Florence city center (reachable by car)

💸 Flights from ~€657

Knoxville main airports to arrive at

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport is a convenient arrival airport for your trip to Knoxville from Florence.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~€656

Airports nearby Knoxville used as alternative

Hartsfield–Jackson Atlanta International (ATL)

Cheapest

Consider Atlanta for unparalleled direct flight options and potential cost savings, despite the longer drive.

📍 ~250 km from Knoxville (reachable by car, ~3.5 to 4 hours drive)

💸 Flights from ~€544

Knoxville, United States

72% AI deal score

$8,295

Air France, +1

Business Class

Frequently Asked Questions About Flights to Knoxville

Cheap Flights from Florence to Knoxville

Today’s best flight deals from Florence to Knoxville

Florence to Knoxville: Overview

Insights for flights from Florence to Knoxville

How much is a round trip from Florence to Knoxville

The cheapest time to fly from Florence to Knoxville

Direct flights from Florence to Knoxville

Last-minute flights going from Florence to Knoxville

Biggest price drops on these dates for flights from Florence to Knoxville

Popular Airports to fly from Florence to Knoxville

Florence - Knoxville route insights

Recent fares are below the typical level

April is historically the cheapest month

Connecting flights average 56h 19m

No direct flights available

Vueling Airlines offers a recent deal

Deals are rare for this route

Florence main airports to depart from

Knoxville main airports to arrive at

Airports nearby Knoxville used as alternative

Business & First Class Flight Deals to Knoxville

Best Elite deals to Knoxville

Oct 30

Sep 21

Nov 11

Sep 21

Dec 17

Dec 26

Dec 17

Dec 18

Dec 20

Dec 18

Dec 18

Dec 20

Frequently Asked Questions About Flights to Knoxville

How can I find cheap flights from Florence to Knoxville?

When should I book flights from Florence to Knoxville?

Should I compare nearby airports for flights from Florence to Knoxville?

Are direct flights from Florence to Knoxville always the best option?

Can flexible travel dates help on Florence to Knoxville flights?

What extra costs should I check before booking Florence to Knoxville flights?

Related routes

More routes from Florence

Flights to Knoxville from other cities

Florence to Knoxville: Overview

Insights for flights from Florence to Knoxville

How much is a round trip from Florence to Knoxville

The cheapest time to fly from Florence to Knoxville

Direct flights from Florence to Knoxville

Last-minute flights going from Florence to Knoxville

Biggest price drops on these dates for flights from Florence to Knoxville

Popular Airports to fly from Florence to Knoxville

Florence - Knoxville route insights

Recent fares are below the typical level

April is historically the cheapest month

Connecting flights average 56h 19m

No direct flights available

Vueling Airlines offers a recent deal

Deals are rare for this route

Florence main airports to depart from

Knoxville main airports to arrive at

Airports nearby Knoxville used as alternative

Business & First Class Flight Deals to Knoxville

Best Elite deals to Knoxville

Oct 30

Sep 21

Nov 11

Sep 21

Dec 17

Dec 26

Dec 17

Dec 18

Dec 20

Dec 18

Dec 18

Dec 20

Frequently Asked Questions About Flights to Knoxville

How can I find cheap flights from Florence to Knoxville?

When should I book flights from Florence to Knoxville?

Should I compare nearby airports for flights from Florence to Knoxville?