Are direct flights from Rome to Knoxville always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, flights with one or more connections can often be more economical. Weigh the trade-off between cost savings and travel duration when making your choice.

Can flexible travel dates help on Rome to Knoxville flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying on weekdays or during off-peak seasons often results in lower fares. Adjusting your departure or return by a few days may unlock better deals.

What extra costs should I check before booking Rome to Knoxville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget.

Flights From Rome

To Knoxville

Cheap Flights from Rome to Knoxville

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Knoxville

Prices updated 7 days ago

483 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)

Today’s best flight deals from Rome to Knoxville

Explore current cheapest deals departing from Rome to Knoxville

2026-12-15 – 2027-01-11
ROM - Knoxville
80% AI deal score
914 €
747 €
Round trip
2026-11-23 – 2026-11-26
ROM - Knoxville
80% AI deal score
919 €
759 €
Round trip
2026-12-11 – 2027-01-08
ROM - Knoxville
79% AI deal score
912 €
767 €
Round trip
2026-11-12 – 2026-11-26
ROM - Knoxville
77% AI deal score
833 €
774 €
Round trip
2026-12-15 – 2027-01-08
ROM - Knoxville
79% AI deal score
914 €
778 €
Round trip
2026-12-09 – 2027-01-08
ROM - Knoxville
79% AI deal score
912 €
779 €
Round trip
2026-12-10 – 2027-01-08
ROM - Knoxville
80% AI deal score
912 €
790 €
Round trip
2026-11-24 – 2026-11-26
ROM - Knoxville
80% AI deal score
926 €
794 €
Round trip
2027-01-06 – 2027-02-01
ROM - Knoxville
74% AI deal score
783 €
797 €
Round trip
2026-11-04 – 2026-11-12
ROM - Knoxville
78% AI deal score
902 €
801 €
Round trip

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

The journey from Rome to Knoxville covers a substantial distance of 7903 km, classifying it as a long-haul flight. This means you should anticipate a significant travel time, often involving multiple connections, to reach your destination.

For travelers seeking cheap flights from Rome to Knoxville, fares typically range from $920 to $1757, with a median price of $1238. Right now, current fares are below the typical level for this route. Only 7% of recent fares were classified as a good price, indicating that finding exceptionally low prices can be challenging. Deals are infrequent, so setting up a price alert could be beneficial.

When considering when is the cheapest time to fly from Rome to Knoxville, October stands out as the most affordable month, with a median fare of $1238.

There are no direct flights from Rome to Knoxville; most itineraries connect at least once. In fact, when connecting, the median number of stopovers is 2, which significantly extends the overall travel duration.

A typical journey from Rome to Knoxville takes approximately 19h 4m including connections. This extended travel time is due to the long-haul nature of the route and the necessity of at least two stopovers for most itineraries.

How much is a round trip from Rome to Knoxville

Regular price: €749 - €1,649

Prices for flights from Rome to Knoxville are currently below the regular range.

Regular prices for this route typically range from 749 EUR to 1649 EUR. The current lowest deal is 684 EUR with Aero Services Executive for travel from Jan 21 to Jan 25.

now 684 €

Low 749 €

High 1,649 €

The cheapest time to fly from Rome to Knoxville

Flights from Rome to Knoxville are generally lower from October to November. The cheapest month to fly is November, with a median price of $1043. The most expensive month is December, with a median price of $1171.

November

Cheapest

Flights from 1,043 €

December

Most Expensive

Flights from 1,171 €

Oct

Nov

Dec

Direct flights from Rome to Knoxville

Allegiant Air

TAP Portugal

Aero Services Executive

Aer Lingus

Last-minute flights going from Rome to Knoxville

Sun, Nov 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,159 €

2,092 €

One-way

Sun, Nov 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,157 €

2,120 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,138 €

1,873 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,126 €

2,078 €

One-way

Tue, Nov 3

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,096 €

1,877 €

One-way

Wed, Nov 4

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,062 €

1,864 €

One-way

Biggest price drops on these dates for flights from Rome to Knoxville

27 nights

Dec 15 - Jan 11

912 € → 728 €

20%

4 nights

Jan 21 - Jan 25

862 € → 717 €

17%

4 nights

Jan 28 - Feb 1

864 € → 739 €

14%

11 nights

Jan 28 - Feb 8

803 € → 728 €

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

💸 Price insights

Recent fares are below the typical level.

Recent fares from Rome to Knoxville are below the typical level, with prices around $684.

📅 Best time to fly

October is historically the cheapest month to fly.

Historically, October has been the cheapest month to fly from Rome to Knoxville, with a median price of $1238.

⏱️ Flight duration

Connecting flights typically take 19h 4m.

Flights from Rome to Knoxville typically involve connections, with a median duration of 19h 4m.

✈️ Airlines & availability

Connecting flights are the only option.

There are no direct flights available; all routes from Rome to Knoxville require at least one stopover.

🏆 Airline highlight

Allegiant Air has 35 direct deals.

Allegiant Air offers 35 direct deals for flights from Rome to Knoxville, more than other airlines.

🎯 Booking tip

Deals on this route are rare.

Deals for flights from Rome to Knoxville are historically rare, appearing infrequently.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport for flights from Rome to Knoxville, often with competitive pricing.

📍 ~24 km from Rome city center (reachable by car or train)

💸 Flights from ~€760

Knoxville main airports to arrive at

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport is a convenient arrival airport for flights from Rome to Knoxville.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~€762

Airports nearby Knoxville used as alternative

Hartsfield–Jackson Atlanta International (ATL)

Cheapest

Hartsfield–Jackson Atlanta International offers unparalleled direct flight options and often provides significant cost savings.

📍 ~290 km from Knoxville (reachable by car)

💸 Flights from ~€465

Business & First Class Flight Deals to Knoxville

Discover luxury on the budget with premium cabin class on flights from Rome to Knoxville.

Elite

Best Elite deals to Knoxville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Dec 20

Knoxville, United States

68% AI deal score

$7,751

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 27

Knoxville, United States

68% AI deal score

$7,758

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 20

Knoxville, United States

68% AI deal score

$7,806

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 14

Knoxville, United States

68% AI deal score

$7,807

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 21

Knoxville, United States

68% AI deal score

$7,807

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 18

Knoxville, United States

68% AI deal score

$7,807

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 17

Knoxville, United States

68% AI deal score

$7,807

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 27

Knoxville, United States

68% AI deal score

$7,814

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 20

Knoxville, United States

68% AI deal score

$7,851

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 27

Knoxville, United States

68% AI deal score

$7,858

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 14

Knoxville, United States

68% AI deal score

$7,862

Scandinavian Airlines, +1

Business Class

From FCO

Elite

Dec 21

Knoxville, United States

68% AI deal score

$7,862

Scandinavian Airlines, +1

Business Class

Frequently Asked Questions About Flights to Knoxville

To find cheaper flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can often reveal better deals. Setting up price alerts can also notify you when fares drop for your desired route.

Booking in advance, often several months ahead, may help secure better prices. However, last-minute deals can sometimes appear, though they are less common. Monitoring price trends can help you decide the optimal booking time for your trip.

Comparing nearby airports for both your origin and destination can sometimes lead to more affordable flight options. While it may add to your ground travel, the potential savings on airfare can be significant. Always factor in the total cost and convenience.

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

When considering when is the cheapest time to fly from Rome to Knoxville, October stands out as the most affordable month, with a median fare of $1238.

How much is a round trip from Rome to Knoxville

Regular price: €749 - €1,649

Prices for flights from Rome to Knoxville are currently below the regular range.

Regular prices for this route typically range from 749 EUR to 1649 EUR. The current lowest deal is 684 EUR with Aero Services Executive for travel from Jan 21 to Jan 25.

now 684 €

Low 749 €

High 1,649 €

The cheapest time to fly from Rome to Knoxville

November

Cheapest

Flights from 1,043 €

December

Most Expensive

Flights from 1,171 €

Oct

Nov

Dec

Direct flights from Rome to Knoxville

Allegiant Air

TAP Portugal

Aero Services Executive

Aer Lingus

Last-minute flights going from Rome to Knoxville

Sun, Nov 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,159 €

2,092 €

One-way

Sun, Nov 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,157 €

2,120 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,138 €

1,873 €

One-way

Mon, Nov 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,126 €

2,078 €

One-way

Tue, Nov 3

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,096 €

1,877 €

One-way

Wed, Nov 4

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,062 €

1,864 €

One-way

Biggest price drops on these dates for flights from Rome to Knoxville

27 nights

Dec 15 - Jan 11

912 € → 728 €

20%

4 nights

Jan 21 - Jan 25

862 € → 717 €

17%

4 nights

Jan 28 - Feb 1

864 € → 739 €

14%

11 nights

Jan 28 - Feb 8

803 € → 728 €

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

💸 Price insights

Recent fares are below the typical level.

Recent fares from Rome to Knoxville are below the typical level, with prices around $684.

📅 Best time to fly

October is historically the cheapest month to fly.

Historically, October has been the cheapest month to fly from Rome to Knoxville, with a median price of $1238.

⏱️ Flight duration

Connecting flights typically take 19h 4m.

Flights from Rome to Knoxville typically involve connections, with a median duration of 19h 4m.

✈️ Airlines & availability

Connecting flights are the only option.

There are no direct flights available; all routes from Rome to Knoxville require at least one stopover.

🏆 Airline highlight

Allegiant Air has 35 direct deals.

Allegiant Air offers 35 direct deals for flights from Rome to Knoxville, more than other airlines.

🎯 Booking tip

Deals on this route are rare.

Deals for flights from Rome to Knoxville are historically rare, appearing infrequently.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport for flights from Rome to Knoxville, often with competitive pricing.

📍 ~24 km from Rome city center (reachable by car or train)

💸 Flights from ~€760

Knoxville main airports to arrive at

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport is a convenient arrival airport for flights from Rome to Knoxville.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~€762

Airports nearby Knoxville used as alternative

Hartsfield–Jackson Atlanta International (ATL)

Cheapest

Hartsfield–Jackson Atlanta International offers unparalleled direct flight options and often provides significant cost savings.

📍 ~290 km from Knoxville (reachable by car)

💸 Flights from ~€465

Knoxville, United States

68% AI deal score

$7,862

Scandinavian Airlines, +1

Business Class

Frequently Asked Questions About Flights to Knoxville

Cheap Flights from Rome to Knoxville

Today’s best flight deals from Rome to Knoxville

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

How much is a round trip from Rome to Knoxville

The cheapest time to fly from Rome to Knoxville

Direct flights from Rome to Knoxville

Last-minute flights going from Rome to Knoxville

Biggest price drops on these dates for flights from Rome to Knoxville

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

Recent fares are below the typical level.

October is historically the cheapest month to fly.

Connecting flights typically take 19h 4m.

Connecting flights are the only option.

Allegiant Air has 35 direct deals.

Deals on this route are rare.

Rome main airports to depart from

Knoxville main airports to arrive at

Airports nearby Knoxville used as alternative

Business & First Class Flight Deals to Knoxville

Best Elite deals to Knoxville

Dec 20

Dec 27

Dec 20

Dec 14

Dec 21

Dec 18

Dec 17

Dec 27

Dec 20

Dec 27

Dec 14

Dec 21

Frequently Asked Questions About Flights to Knoxville

How can I find cheap flights from Rome to Knoxville?

When should I book flights from Rome to Knoxville?

Should I compare nearby airports for flights from Rome to Knoxville?

Are direct flights from Rome to Knoxville always the best option?

Can flexible travel dates help on Rome to Knoxville flights?

What extra costs should I check before booking Rome to Knoxville flights?

Related routes

More routes from Rome

Flights to Knoxville from other cities

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

How much is a round trip from Rome to Knoxville

The cheapest time to fly from Rome to Knoxville

Direct flights from Rome to Knoxville

Last-minute flights going from Rome to Knoxville

Biggest price drops on these dates for flights from Rome to Knoxville

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

Recent fares are below the typical level.

October is historically the cheapest month to fly.

Connecting flights typically take 19h 4m.

Connecting flights are the only option.

Allegiant Air has 35 direct deals.

Deals on this route are rare.

Rome main airports to depart from

Knoxville main airports to arrive at

Airports nearby Knoxville used as alternative

Business & First Class Flight Deals to Knoxville

Best Elite deals to Knoxville

Dec 20

Dec 27

Dec 20

Dec 14

Dec 21

Dec 18

Dec 17

Dec 27

Dec 20

Dec 27

Dec 14

Dec 21

Frequently Asked Questions About Flights to Knoxville

How can I find cheap flights from Rome to Knoxville?

When should I book flights from Rome to Knoxville?

Should I compare nearby airports for flights from Rome to Knoxville?