Are direct flights from Rome to Knoxville always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers, but they are not always the most economical choice. Flights with one or more connections can often be less expensive. Consider your budget and time constraints when deciding between direct and connecting flights.

Can flexible travel dates help on Rome to Knoxville flights?

Yes, having flexible travel dates can significantly increase your chances of finding cheaper flights. Prices often vary depending on the day of the week and the season. Flying during off-peak days or seasons may result in substantial savings on your airfare.

What extra costs should I check before booking Rome to Knoxville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factoring these into your total budget helps avoid surprises.

Flights From Rome

To Knoxville

Cheap Flights from Rome to Knoxville

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Knoxville

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Rome to Knoxville

Explore current cheapest deals departing from Rome to Knoxville

2026-09-29 – 2026-10-16
ROM - Knoxville
87% AI deal score
832 €
642 €
Round trip
2026-09-29 – 2026-10-22
ROM - Knoxville
85% AI deal score
830 €
644 €
Round trip
2026-09-03 – 2026-09-14
ROM - Knoxville
86% AI deal score
847 €
657 €
Round trip
2026-10-02 – 2026-10-16
ROM - Knoxville
88% AI deal score
886 €
660 €
Round trip
2026-09-29 – 2026-10-19
ROM - Knoxville
85% AI deal score
830 €
665 €
Round trip
2026-10-07 – 2026-10-12
ROM - Knoxville
90% AI deal score
947 €
679 €
Round trip
2026-09-04 – 2026-09-14
ROM - Knoxville
85% AI deal score
849 €
685 €
Round trip
2026-09-29 – 2026-10-21
ROM - Knoxville
81% AI deal score
830 €
688 €
Round trip
2026-09-29 – 2026-10-14
ROM - Knoxville
81% AI deal score
832 €
691 €
Round trip
2026-10-02 – 2026-10-21
ROM - Knoxville
86% AI deal score
874 €
706 €
Round trip

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

The journey from Rome to Knoxville covers a substantial distance of 7903 km, classifying it as a long-haul flight. This significant distance means travelers should expect a longer travel duration and typically more complex itineraries.

For those seeking cheap flights from Rome to Knoxville, fares typically range from $978 to $1331, with a median price of $1056. Right now, current fares are significantly below the typical level. Approximately 20% of recent fares for this route were classified as a good price, indicating that competitive offers do appear, though not frequently. New deals for this route are infrequent — a price alert helps to catch them.

When considering the cheapest time to fly from Rome to Knoxville, May stands out with a median fare of $1041. Following closely, April offers a median fare of $1058, and June presents a median of $1062. These months generally offer more favorable pricing compared to other periods.

There are currently no direct flights from Rome to Knoxville, meaning all itineraries involve connections. Most itineraries for this route connect at least once, with a typical number of 2 stopovers when connecting. This is an important factor to consider when planning your travel time.

A typical journey from Rome to Knoxville, including connections, takes approximately 55h 55m. Given that all itineraries involve at least one stopover, this duration reflects the combined time of flights and layovers. Travelers should factor in this extended travel time when making plans.

How much is a round trip from Rome to Knoxville

Regular price: €806 - €1,356

Prices are currently below the regular range for flights from Rome to Knoxville.

The regular price range for flights from Rome to Knoxville is 806 EUR to 1356 EUR. The current lowest deal is 683 EUR with Iberia Airlines for travel from Oct 7-Oct 12.

now 683 €

Low 806 €

High 1,356 €

The cheapest time to fly from Rome to Knoxville

The cheapest month to fly from Rome to Knoxville is May, with a median price of $1041. The most expensive month is June, with a median price of $1062. Prices are generally lower from April to May.

May

Cheapest

Flights from 1,041 €

June

Most Expensive

Flights from 1,062 €

Apr

May

Jun

Direct flights from Rome to Knoxville

Allegiant Air

Iberia Airlines

KLM

Ryanair

Last-minute flights going from Rome to Knoxville

Fri, Aug 7

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Deutsche Luft Hansa

1,196 €

879 €

One-way

Sat, Aug 8

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Deutsche Luft Hansa

1,183 €

891 €

One-way

Sun, Aug 9

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

United Airlines

1,162 €

1,219 €

One-way

Mon, Aug 24

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Iberia Airlines

1,046 €

886 €

One-way

Sat, Aug 29

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

KLM, Iberia Airlines

1,058 €

1,407 €

One-way

Sat, Aug 29

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

KLM, Iberia Airlines

954 €

1,442 €

One-way

Biggest price drops on these dates for flights from Rome to Knoxville

4 nights

Aug 7 - Aug 11

1,196 € → 879 €

26%

4 nights

Aug 8 - Aug 12

1,183 € → 891 €

25%

4 nights

Nov 26 - Nov 30

952 € → 695 €

27%

4 nights

Oct 7 - Oct 11

961 € → 721 €

25%

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Knoxville are below the typical level at $683.

📅 Best time to fly

Fly in May for the best prices

Historically, May has offered the lowest median prices at $1041 for this route.

⏱️ Flight duration

Expect long-haul flights

Flights from Rome to Knoxville typically take 55h 55m, with 2 stopovers.

✈️ Airlines & availability

Connecting flights are dominant

There are no direct flights available; connecting flights are the only option.

🏆 Airline highlight

Iberia Airlines offers a recent deal

Iberia Airlines recently offered a deal for $683 from Rome to Knoxville.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Rome to Knoxville are historically rare.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Leonardo da Vinci–Fiumicino Airport is a good option for flights from Rome to Knoxville.

📍 ~25 km from Rome city center (reachable by car or train)

💸 Flights from ~$771

Ciampino–G. B. Pastine International (CIA)

Ciampino–G. B. Pastine International is an alternative for flights from Rome to Knoxville.

📍 ~15 km from Rome city center (reachable by car or train)

💸 Flights from ~$1073

Knoxville main airports to arrive at

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport is a convenient arrival point for flights from Rome to Knoxville.

📍 ~20 km from Knoxville (reachable by car)

💸 Flights from ~$771

Airports nearby Knoxville used as alternative

Nashville International (BNA)

Cheapest

Nashville International is a major international hub with significantly more direct flight options and competitive pricing.

📍 ~240 km from Knoxville (reachable by car)

💸 Flights from ~$578

Business & First Class Flight Deals to Knoxville

Discover luxury on the budget with premium cabin class on flights from Rome to Knoxville.

Elite

Best Elite deals to Knoxville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Jul 01

Knoxville, United States

75% AI deal score

Knoxville, United States

73% AI deal score

$3,162

From FCO

Elite

Aug 18

Knoxville, United States

73% AI deal score

$3,162

Frequently Asked Questions About Flights to Knoxville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can often reveal better deals. Looking into flights with layovers instead of direct routes may also present cheaper options.

Booking in advance, often several months before your intended departure, can sometimes result in lower fares. However, prices can fluctuate, so monitoring flight prices over a period may help you identify optimal booking times. Avoiding peak travel seasons can also lead to savings.

Comparing nearby airports at both your origin and destination can sometimes uncover more affordable flight options. While it may involve extra travel time to and from these airports, the potential savings on airfare can be significant. Always factor in the cost and convenience of ground transportation.

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

How much is a round trip from Rome to Knoxville

Regular price: €806 - €1,356

Prices are currently below the regular range for flights from Rome to Knoxville.

The regular price range for flights from Rome to Knoxville is 806 EUR to 1356 EUR. The current lowest deal is 683 EUR with Iberia Airlines for travel from Oct 7-Oct 12.

now 683 €

Low 806 €

High 1,356 €

The cheapest time to fly from Rome to Knoxville

The cheapest month to fly from Rome to Knoxville is May, with a median price of $1041. The most expensive month is June, with a median price of $1062. Prices are generally lower from April to May.

May

Cheapest

Flights from 1,041 €

June

Most Expensive

Flights from 1,062 €

Apr

May

Jun