Are direct flights from Rome to Knoxville always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers, but they are not always the most economical choice. Flights with one or more stops can often be significantly cheaper, especially for longer international routes. Consider your budget and time constraints when deciding between direct and connecting flights.

Can flexible travel dates help on Rome to Knoxville flights?

Yes, being flexible with your travel dates can significantly impact the price of your flight. Mid-week flights or those during off-peak seasons often have lower fares than weekend or holiday travel. Adjusting your departure or return by even a few days may lead to substantial savings.

What extra costs should I check before booking Rome to Knoxville flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight meal costs. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Rome

To Knoxville

Cheap Flights from Rome to Knoxville

Browse current best options from Rome. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Rome

RatePunk searches hundreds of travel sites at once for deals on flights to Knoxville

Prices updated 1 day ago

456 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 2, 2026.)

Today’s best flight deals from Rome to Knoxville

Explore current cheapest deals departing from Rome to Knoxville

2026-11-12 – 2026-12-04
ROM - Knoxville
80% AI deal score
803 €
690 €
Round trip
2026-12-01 – 2026-12-04
ROM - Knoxville
90% AI deal score
1,016 €
690 €
Round trip
2026-10-19 – 2026-11-04
ROM - Knoxville
85% AI deal score
847 €
692 €
Round trip
2026-10-27 – 2026-11-04
ROM - Knoxville
85% AI deal score
879 €
695 €
Round trip
2026-10-28 – 2026-11-04
ROM - Knoxville
86% AI deal score
904 €
695 €
Round trip
2026-10-20 – 2026-11-04
ROM - Knoxville
80% AI deal score
850 €
706 €
Round trip
2026-11-10 – 2026-12-04
ROM - Knoxville
79% AI deal score
802 €
711 €
Round trip
2026-10-26 – 2026-11-04
ROM - Knoxville
80% AI deal score
879 €
718 €
Round trip
2026-09-10 – 2026-09-14
ROM - Knoxville
91% AI deal score
1,034 €
726 €
Round trip
2026-10-22 – 2026-11-04
ROM - Knoxville
79% AI deal score
859 €
731 €
Round trip

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

Right now, if you are looking for cheap flights from Rome to Knoxville, fares are significantly below the typical level. Prices for this route typically range from $978–$1331, with a median of $1056. Currently, about 20% of recent fares are considered a good price for this long-haul journey. New deals for this route are infrequent, so setting up a price alert can be beneficial.

When is the cheapest time to fly from Rome to Knoxville? Based on recent data, the most affordable month to fly is May, with a median fare of $1041. Following closely are April, with a median of $1058, and June, where the median fare is $1062. These months offer the most competitive pricing for this route.

For flights from Rome to Knoxville, most itineraries connect at least once. There are no direct flights from Rome to Knoxville, meaning all journeys will include connections. When connecting, the typical number of stopovers is 2, which impacts the overall travel time.

How long is the flight from Rome to Knoxville? A typical journey, including connections, takes approximately 55h 55m. This duration reflects the fact that all itineraries involve at least one stopover, extending the total travel time significantly.

How much is a round trip from Rome to Knoxville

Regular price: €843 - €1,089

Prices are currently below the regular range.

Regular prices for flights from Rome to Knoxville typically range from 843 EUR to 1089 EUR. The current lowest deal is 649 EUR with Deutsche Luft Hansa, for travel from Mar 20-Mar 29.

now 649 €

Low 843 €

High 1,089 €

The cheapest time to fly from Rome to Knoxville

The cheapest month to fly from Rome to Knoxville is May, with a median price of $1041. The most expensive month is June, with a median price of $1062. Prices are generally lower from April to May.

May

Cheapest

Flights from 1,041 €

June

Most Expensive

Flights from 1,062 €

Apr

May

Jun

Direct flights from Rome to Knoxville

Allegiant Air

Aer Lingus

TAP Portugal

Aero Services Executive

Last-minute flights going from Rome to Knoxville

Tue, Sep 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,075 €

1,635 €

One-way

Tue, Sep 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,019 €

1,635 €

One-way

Wed, Sep 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,059 €

1,629 €

One-way

Wed, Sep 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,059 €

1,629 €

One-way

Wed, Sep 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,222 €

1,629 €

One-way

Thu, Sep 3

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,135 €

1,629 €

One-way

Biggest price drops on these dates for flights from Rome to Knoxville

4 nights

Sep 10 - Sep 14

1,030 € → 723 €

30%

4 nights

Sep 12 - Sep 16

1,013 € → 738 €

27%

7 nights

Oct 8 - Oct 15

901 € → 728 €

19%

6 nights

Sep 24 - Sep 30

878 € → 736 €

16%

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Knoxville are below the typical level at $649.

📅 Best time to fly

Fly in May for the best prices

Historically, May offers the lowest median price at $1041 for this route.

⏱️ Flight duration

Connecting flights average 55h 55m

Flights from Rome to Knoxville typically involve 2 stopovers, averaging 55h 55m.

✈️ Airlines & availability

Connecting flights are dominant

Direct flights are not available for this route; connecting flights are dominant.

🏆 Airline highlight

Deutsche Luft Hansa has a recent deal

A recent deal for $649 from Rome to Knoxville was found on Deutsche Luft Hansa.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Rome to Knoxville are historically rare.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport for flights from Rome to Knoxville, often with competitive pricing.

📍 ~24 km from Rome city center (reachable by car or train)

💸 Flights from ~€650

Ciampino–G. B. Pastine International (CIA)

Consider Ciampino–G. B. Pastine International for your journey from Rome to Knoxville.

📍 ~14 km from Rome city center (reachable by car or train)

💸 Flights from ~€1,053

Knoxville main airports to arrive at

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport (TYS) is a convenient arrival choice for flights from Rome to Knoxville.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~€649

Airports nearby Knoxville used as alternative

Hartsfield–Jackson Atlanta International (ATL)

Cheapest

Hartsfield–Jackson Atlanta International often provides significant cost savings on international and domestic routes.

📍 ~250 km from Knoxville (reachable by car)

💸 Flights from ~€550

Business & First Class Flight Deals to Knoxville

Discover luxury on the budget with premium cabin class on flights from Rome to Knoxville.

Elite

Best Elite deals to Knoxville

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From FCO

Elite

Oct 23

Knoxville, United States

74% AI deal score

$2,657

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 18

Knoxville, United States

74% AI deal score

$2,855

Condor Flugdienst, +1

Business Class

From FCO

Elite

Sep 30

Knoxville, United States

74% AI deal score

$2,866

Condor Flugdienst, +1

Business Class

From FCO

Elite

Sep 29

Knoxville, United States

74% AI deal score

$2,949

Iberia Airlines, +1

Business Class

From FCO

Elite

Oct 23

Knoxville, United States

74% AI deal score

$3,129

Condor Flugdienst, +1

Business Class

From FCO

Elite

Oct 18

Knoxville, United States

73% AI deal score

$3,163

Condor Flugdienst, +1

Business Class

From FCO

Elite

Sep 30

Knoxville, United States

73% AI deal score

$3,174

Condor Flugdienst, +1

Business Class

From FCO

Elite

Sep 08

Knoxville, United States

73% AI deal score

$3,210

Air Transat, +1

Business Class

From FCO

Elite

Oct 18

Knoxville, United States

73% AI deal score

$3,215

Condor Flugdienst, +1

Business Class

From FCO

Elite

Sep 30

Knoxville, United States

73% AI deal score

$3,225

Condor Flugdienst, +1

Business Class

From FCO

Elite

Sep 12

Knoxville, United States

73% AI deal score

$3,228

Air Transat, +1

Business Class

From FCO

Elite

Oct 18

Knoxville, United States

73% AI deal score

$3,231

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Knoxville

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you identify better deals. Looking into flights with layovers may sometimes present lower fares than direct routes.

Booking flights in advance, often several months before your intended travel date, can sometimes result in better prices. However, last-minute deals can occasionally appear, so monitoring prices is usually a good strategy. Prices can fluctuate, so there isn't one universal best time.

Yes, comparing nearby airports for both your origin and destination can often uncover more flight options and potentially lower prices. Sometimes, flying into or out of a smaller airport a short distance away may offer significant savings. Always factor in the cost and time of ground transportation to these alternative airports.

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

How much is a round trip from Rome to Knoxville

Regular price: €843 - €1,089

Prices are currently below the regular range.

Regular prices for flights from Rome to Knoxville typically range from 843 EUR to 1089 EUR. The current lowest deal is 649 EUR with Deutsche Luft Hansa, for travel from Mar 20-Mar 29.

now 649 €

Low 843 €

High 1,089 €

The cheapest time to fly from Rome to Knoxville

The cheapest month to fly from Rome to Knoxville is May, with a median price of $1041. The most expensive month is June, with a median price of $1062. Prices are generally lower from April to May.

May

Cheapest

Flights from 1,041 €

June

Most Expensive

Flights from 1,062 €

Apr

May

Jun

Direct flights from Rome to Knoxville

Allegiant Air

Aer Lingus

TAP Portugal

Aero Services Executive

Last-minute flights going from Rome to Knoxville

Tue, Sep 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,075 €

1,635 €

One-way

Tue, Sep 1

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,019 €

1,635 €

One-way

Wed, Sep 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,059 €

1,629 €

One-way

Wed, Sep 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,059 €

1,629 €

One-way

Wed, Sep 2

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,222 €

1,629 €

One-way

Thu, Sep 3

⌛ Last-Minute

FCO - Knoxville

Rome (FCO) - Knoxville (TYS)

Aer Lingus

1,135 €

1,629 €

One-way

Biggest price drops on these dates for flights from Rome to Knoxville

4 nights

Sep 10 - Sep 14

1,030 € → 723 €

30%

4 nights

Sep 12 - Sep 16

1,013 € → 738 €

27%

7 nights

Oct 8 - Oct 15

901 € → 728 €

19%

6 nights

Sep 24 - Sep 30

878 € → 736 €

16%

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Rome to Knoxville are below the typical level at $649.

📅 Best time to fly

Fly in May for the best prices

Historically, May offers the lowest median price at $1041 for this route.

⏱️ Flight duration

Connecting flights average 55h 55m

Flights from Rome to Knoxville typically involve 2 stopovers, averaging 55h 55m.

✈️ Airlines & availability

Connecting flights are dominant

Direct flights are not available for this route; connecting flights are dominant.

🏆 Airline highlight

Deutsche Luft Hansa has a recent deal

A recent deal for $649 from Rome to Knoxville was found on Deutsche Luft Hansa.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Rome to Knoxville are historically rare.

Rome main airports to depart from

Leonardo da Vinci–Fiumicino Airport (FCO)

Cheapest

Fly from Leonardo da Vinci–Fiumicino Airport for flights from Rome to Knoxville, often with competitive pricing.

📍 ~24 km from Rome city center (reachable by car or train)

💸 Flights from ~€650

Ciampino–G. B. Pastine International (CIA)

Consider Ciampino–G. B. Pastine International for your journey from Rome to Knoxville.

📍 ~14 km from Rome city center (reachable by car or train)

💸 Flights from ~€1,053

Knoxville main airports to arrive at

McGhee Tyson (TYS)

Cheapest

McGhee Tyson Airport (TYS) is a convenient arrival choice for flights from Rome to Knoxville.

📍 ~18 km from Knoxville (reachable by car)

💸 Flights from ~€649

Airports nearby Knoxville used as alternative

Hartsfield–Jackson Atlanta International (ATL)

Cheapest

Hartsfield–Jackson Atlanta International often provides significant cost savings on international and domestic routes.

📍 ~250 km from Knoxville (reachable by car)

💸 Flights from ~€550

Knoxville, United States

73% AI deal score

$3,231

Condor Flugdienst, +1

Business Class

Frequently Asked Questions About Flights to Knoxville

Cheap Flights from Rome to Knoxville

Today’s best flight deals from Rome to Knoxville

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

How much is a round trip from Rome to Knoxville

The cheapest time to fly from Rome to Knoxville

Direct flights from Rome to Knoxville

Last-minute flights going from Rome to Knoxville

Biggest price drops on these dates for flights from Rome to Knoxville

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

Recent fares are below the typical level

Fly in May for the best prices

Connecting flights average 55h 55m

Connecting flights are dominant

Deutsche Luft Hansa has a recent deal

Deals are rare for this route

Rome main airports to depart from

Knoxville main airports to arrive at

Airports nearby Knoxville used as alternative

Business & First Class Flight Deals to Knoxville

Best Elite deals to Knoxville

Oct 23

Oct 18

Sep 30

Sep 29

Oct 23

Oct 18

Sep 30

Sep 08

Oct 18

Sep 30

Sep 12

Oct 18

Frequently Asked Questions About Flights to Knoxville

How can I find cheap flights from Rome to Knoxville?

When should I book flights from Rome to Knoxville?

Should I compare nearby airports for flights from Rome to Knoxville?

Are direct flights from Rome to Knoxville always the best option?

Can flexible travel dates help on Rome to Knoxville flights?

What extra costs should I check before booking Rome to Knoxville flights?

Related routes

More routes from Rome

Flights to Knoxville from other cities

Rome to Knoxville: Overview

Insights for flights from Rome to Knoxville

How much is a round trip from Rome to Knoxville

The cheapest time to fly from Rome to Knoxville

Direct flights from Rome to Knoxville

Last-minute flights going from Rome to Knoxville

Biggest price drops on these dates for flights from Rome to Knoxville

Popular Airports to fly from Rome to Knoxville

Rome - Knoxville route insights

Recent fares are below the typical level

Fly in May for the best prices

Connecting flights average 55h 55m

Connecting flights are dominant

Deutsche Luft Hansa has a recent deal

Deals are rare for this route

Rome main airports to depart from

Knoxville main airports to arrive at

Airports nearby Knoxville used as alternative

Business & First Class Flight Deals to Knoxville

Best Elite deals to Knoxville

Oct 23

Oct 18

Sep 30

Sep 29

Oct 23

Oct 18

Sep 30

Sep 08

Oct 18

Sep 30

Sep 12

Oct 18

Frequently Asked Questions About Flights to Knoxville

How can I find cheap flights from Rome to Knoxville?

When should I book flights from Rome to Knoxville?

Should I compare nearby airports for flights from Rome to Knoxville?