FlightsFrom Southampton

To Knoxville

Cheap Flights from Southampton to Knoxville

Browse current best options from Southampton. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Southampton

RatePunk searches hundreds of travel sites at once for deals on flights to Knoxville

Prices updated today

485 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Nov 2, 2026.)

Today’s best flight deals from Southampton to Knoxville

Explore current cheapest deals departing from Southampton to Knoxville