Are direct flights from Santiago de Chile to Panama City always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, connecting flights can often be more affordable, especially if you are willing to accept a longer journey. Evaluate your priorities for cost versus travel time.

Can flexible travel dates help on Santiago de Chile to Panama City flights?

Being flexible with your travel dates can significantly impact the price of your flight. Mid-week flights or those during off-peak seasons are often less expensive. Adjusting your departure or return by a few days may lead to considerable savings.

What extra costs should I check before booking Santiago de Chile to Panama City flights?

Always review potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Factor these into your total travel budget to avoid surprises.

Flights From Santiago de Chile

To Panama City

Cheap Flights from Santiago de Chile to Panama City

Browse current best options from Santiago de Chile. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Santiago de Chile

RatePunk searches hundreds of travel sites at once for deals on flights to Panama City

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Santiago de Chile to Panama City

Explore current cheapest deals departing from Santiago de Chile to Panama City

2026-08-19 – 2026-08-26
SCL - Panama
69% AI deal score
$544
$580
Round trip
2026-08-15 – 2026-08-22
SCL - Panama
67% AI deal score
$558
$620
Round trip
2026-08-17 – 2026-08-24
SCL - Panama
67% AI deal score
$558
$620
Round trip
2026-08-18 – 2026-08-25
SCL - Panama
67% AI deal score
$558
$620
Round trip
2026-08-18 – 2026-08-28
SCL - Panama
67% AI deal score
$517
$620
Round trip
2026-08-18 – 2026-08-29
SCL - Panama
67% AI deal score
$512
$620
Round trip
2026-08-20 – 2026-08-26
SCL - Panama
67% AI deal score
$559
$620
Round trip
2026-08-21 – 2026-08-29
SCL - Panama
67% AI deal score
$536
$620
Round trip
2026-08-22 – 2026-08-26
SCL - Panama
67% AI deal score
$577
$620
Round trip
2026-08-24 – 2026-08-29
SCL - Panama
67% AI deal score
$570
$620
Round trip

Santiago de Chile to Panama City: Overview

Insights for flights from Santiago de Chile to Panama City

For cheap flights from Santiago de Chile to Panama City, fares typically range from $839–$1617, with a median of $1095. Right now, fares are below the typical level, though the share of recent fares classified as a good price is 0%.

When is the cheapest time to fly from Santiago de Chile to Panama City? The most affordable months to fly are February, with a median fare of $737, followed by November at $740, and October at $772.

A typical journey from Santiago de Chile to Panama City takes 27h 36m, including connections. Most itineraries connect at least once, with the median number of stopovers for connecting flights being 2.

This route covers a considerable distance of 7262 km, categorizing it as a long-haul journey. New deals for this route appear almost daily, indicating frequent opportunities for travelers.

How much is a round trip from Santiago de Chile to Panama City

Regular price: $349 - $767

Prices for flights from Santiago de Chile to Panama are currently within the regular range.

The regular price range for flights from Santiago de Chile to Panama is between $349 and $767. The current lowest deal is $501 with Kayak, for travel from Oct 28-Nov 8.

now $501

Low $349

High $767

The cheapest time to fly from Santiago de Chile to Panama City

The cheapest month to fly from SCL to ECP is February, with a median price of $737. The most expensive month is May, with a median price of $1214. Prices are generally lower from January to November.

February

Cheapest

Flights from $737

May

Most Expensive

Flights from $1,214

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Santiago de Chile to Panama City

United Airlines

Avianca

WestJet

B&H Airlines

Last-minute flights going from Santiago de Chile to Panama City

Mon, Aug 10

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$897

$1,349

One-way

Fri, Aug 14

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$878

$1,598

One-way

Sat, Aug 15

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$875

$1,448

One-way

Sun, Aug 16

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$877

$1,456

One-way

Sun, Aug 16

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$820

$1,589

One-way

Mon, Aug 17

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$879

$1,389

One-way

Biggest price drops on these dates for flights from Santiago de Chile to Panama City

4 nights

Sep 24 - Sep 28

$806 → $620

23%

3 nights

Sep 25 - Sep 28

$806 → $620

23%

5 nights

Sep 22 - Sep 27

$805 → $620

23%

6 nights

Sep 30 - Oct 6

$785 → $620

21%

Popular Airports to fly from Santiago de Chile to Panama City

Santiago de Chile - Panama City route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Santiago de Chile to Panama City are below the typical level at $1095.

📅 Best time to fly

February is historically cheapest

Historically, February is the cheapest month to fly, with a median price of $737.

⏱️ Flight duration

Connecting flights take 27h 36m

Flights from Santiago de Chile to Panama City typically involve connections, with a median duration of 27h 36m.

✈️ Airlines & availability

Connecting flights are dominant

This route is dominated by connecting flights, with a median of 2 stopovers.

🏆 Airline highlight

United Airlines offers 25 deals

United Airlines has offered 25 deals on this route recently, making it a frequent provider.

🎯 Booking tip

Deals are frequent on this route

Deals for flights from Santiago de Chile to Panama City are frequent, appearing often.

Santiago de Chile main airports to depart from

Comodoro Arturo Merino Benítez International (SCL)

Cheapest

Fly from Santiago de Chile to Panama City with competitive prices from Comodoro Arturo Merino Benítez International Airport.

📍 ~15 km from city center (reachable by car)

💸 Flights from ~$610

Panama City main airports to arrive at

Northwest Florida Beaches International (ECP)

Cheapest

Northwest Florida Beaches International Airport is a good arrival choice for flights to Panama City.

📍 ~25 km from Panama City (reachable by car)

💸 Flights from ~$878

Airports nearby Panama City used as alternative

Destin–Fort Walton Beach (VPS)

Destin–Fort Walton Beach Airport can be a useful alternative due to its proximity and frequent flight options.

📍 ~100 km from Panama City (traffic on Highway 98 can impact travel time).

💸 Flights from ~$705

Business & First Class Flight Deals to Panama City

Discover luxury on the budget with premium cabin class on flights from Santiago de Chile to Panama City.

Elite

Best Elite deals to Panama City

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From SCL

Elite

Jul 19

Panama City, United States

69% AI deal score

$7,932

From SCL

Elite

Jul 20

Panama City, United States

69% AI deal score

$8,007

From SCL

Elite

Jul 13

Panama City, United States

67% AI deal score

$9,396

From SCL

Elite

Jul 14

Panama City, United States

67% AI deal score

$6,734

Frequently Asked Questions About Flights to Panama City

To find more affordable flights, consider being flexible with your travel dates and times. Using flight comparison sites can help you compare options from various airlines and online travel agencies. Look out for deals and promotions that may be available.

Booking in advance can often lead to better prices, especially for international routes. However, last-minute deals can sometimes appear, though they are less predictable. Monitoring price trends over several weeks may help you decide the optimal booking time.

Comparing nearby airports can sometimes reveal more economical flight options or different travel itineraries. While it may add to your ground transportation, the potential savings could be significant. Always check the total cost and convenience when considering this.

Related routes

More routes from Santiago de Chile

Flights to Panama City from other cities

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Santiago de Chile to Panama City: Overview

Insights for flights from Santiago de Chile to Panama City

This route covers a considerable distance of 7262 km, categorizing it as a long-haul journey. New deals for this route appear almost daily, indicating frequent opportunities for travelers.

How much is a round trip from Santiago de Chile to Panama City

Regular price: $349 - $767

Prices for flights from Santiago de Chile to Panama are currently within the regular range.

The regular price range for flights from Santiago de Chile to Panama is between $349 and $767. The current lowest deal is $501 with Kayak, for travel from Oct 28-Nov 8.

now $501

Low $349

High $767

The cheapest time to fly from Santiago de Chile to Panama City

The cheapest month to fly from SCL to ECP is February, with a median price of $737. The most expensive month is May, with a median price of $1214. Prices are generally lower from January to November.

February

Cheapest

Flights from $737

May

Most Expensive

Flights from $1,214

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Santiago de Chile to Panama City

United Airlines

Avianca

WestJet

B&H Airlines

Last-minute flights going from Santiago de Chile to Panama City

Mon, Aug 10

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$897

$1,349

One-way

Fri, Aug 14

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$878

$1,598

One-way

Sat, Aug 15

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$875

$1,448

One-way

Sun, Aug 16

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$877

$1,456

One-way

Sun, Aug 16

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$820

$1,589

One-way

Mon, Aug 17

⌛ Last-Minute

SCL - Panama City

Santiago de Chile (SCL) - Panama City (ECP)

United Airlines

$879

$1,389

One-way

Biggest price drops on these dates for flights from Santiago de Chile to Panama City

4 nights

Sep 24 - Sep 28

$806 → $620

23%

3 nights

Sep 25 - Sep 28

$806 → $620

23%

5 nights

Sep 22 - Sep 27

$805 → $620

23%

6 nights

Sep 30 - Oct 6

$785 → $620

21%

Popular Airports to fly from Santiago de Chile to Panama City