Are direct flights from Guayaquil to Panama City always the best option?

Direct flights offer convenience by minimizing travel time and avoiding layovers. However, connecting flights can sometimes be more economical, especially if you are open to longer travel durations. Consider your priorities for cost versus convenience when making your choice.

Can flexible travel dates help on Guayaquil to Panama City flights?

Yes, having flexible travel dates can significantly increase your chances of finding cheaper flights. Prices for flights can vary greatly depending on the day of the week or even the time of day. Adjusting your departure or return by a day or two may lead to savings.

What extra costs should I check before booking Guayaquil to Panama City flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Being aware of these additional fees can help you budget accurately for your trip.

Flights From Guayaquil

To Panama City

Cheap Flights from Guayaquil to Panama City

Browse current best options from Guayaquil. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Guayaquil

RatePunk searches hundreds of travel sites at once for deals on flights to Panama City

Prices updated 4 days ago

476 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 12, 2026.)

Today’s best flight deals from Guayaquil to Panama City

Explore current cheapest deals departing from Guayaquil to Panama City

2027-02-06 – 2027-02-09
GYE - Panama City
70% AI deal score
$668
$1,027
Round trip
2026-11-26 – 2026-11-30
GYE - Panama City
68% AI deal score
$521
$1,156
Round trip
2026-11-18 – 2026-11-23
GYE - Panama City
49% AI deal score
$516
$1,622
Round trip
2026-11-13 – 2026-11-23
GYE - Panama City
49% AI deal score
$479
$1,624
Round trip
2026-10-28 – 2026-11-23
GYE - Panama City
46% AI deal score
$462
$1,638
Round trip
2026-10-25 – 2026-11-23
GYE - Panama City
45% AI deal score
$463
$1,690
Round trip
2026-11-18 – 2026-11-24
GYE - Panama City
48% AI deal score
$503
$1,757
Round trip
2026-10-26 – 2026-11-23
GYE - Panama City
44% AI deal score
$460
$1,769
Round trip
2026-10-28 – 2026-11-11
GYE - Panama City
45% AI deal score
$483
$1,796
Round trip
2026-10-28 – 2026-11-01
GYE - Panama City
44% AI deal score
$558
$1,829
Round trip

Guayaquil to Panama City: Overview

Insights for flights from Guayaquil to Panama City

For cheap flights from Guayaquil to Panama City, fares right now are significantly below the typical level. Prices for this route typically range from $897 to $1554, with a median of $1120. Currently, 0% of recent fares are classified as a good price, indicating that finding exceptional value may require careful timing.

When is the cheapest time to fly from Guayaquil to Panama City? The most affordable month to fly is typically August, with a median fare of $607. Other cost-effective options include March, with a median fare of $847, and September, where the median fare is $891. Planning your trip during these months could lead to more favorable pricing.

A typical journey from Guayaquil to Panama City takes approximately 23h 53m, including connections. This is a route where most itineraries connect at least once. For connecting flights, the median number of stopovers is 3, which significantly contributes to the overall travel time.

The distance between Guayaquil and Panama City is 3670 kilometers, classifying this as a medium-haul route. This distance typically involves a longer travel duration, especially given that direct flights are not common on this route. Deals for this route are infrequent, so setting up a price alert can be beneficial.

How much is a round trip from Guayaquil to Panama City

Regular price: $518 - $1,391

Prices for flights from Guayaquil to Panama City are currently within the regular range.

The regular price range for this route is between $518 and $1391. The current lowest deal is $896 with United Airlines for travel from Feb 1-Feb 10.

now $896

Low $518

High $1,391

The cheapest time to fly from Guayaquil to Panama City

The cheapest month to fly from GYE to ECP is February, with a median price of $1027. The most expensive month is October, with a median price of $1831. Prices are generally lower from February to December.

February

Cheapest

Flights from $1,027

October

Most Expensive

Flights from $1,831

Feb

Oct

Nov

Dec

Direct flights from Guayaquil to Panama City

WestJet

Avianca

Air Canada

United Airlines

Last-minute flights going from Guayaquil to Panama City

Mon, Oct 12

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$740

$5,777

One-way

Thu, Oct 22

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$489

$1,848

One-way

Mon, Oct 26

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$463

$1,626

One-way

Mon, Oct 26

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$473

$1,746

One-way

Mon, Oct 26

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$463

$1,948

One-way

Tue, Oct 27

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$460

$1,626

One-way

Biggest price drops on these dates for flights from Guayaquil to Panama City

3 nights

Feb 6 - Feb 9

$668 → $1,027

54%

4 nights

Nov 26 - Nov 30

$521 → $1,156

122%

5 nights

Nov 18 - Nov 23

$516 → $1,624

214%

10 nights

Nov 13 - Nov 23

$479 → $1,624

239%

Popular Airports to fly from Guayaquil to Panama City

Guayaquil - Panama City route insights

💸 Price insights

Recent fares are below the typical level

Recent fares for this route are below the typical level, with deals from $896.

📅 Best time to fly

Fly in August for the best prices

Historically, August is the cheapest month to fly, with a median price of $607.

⏱️ Flight duration

Connecting flights take 23h 53m

Flights from Guayaquil to Panama City typically involve connections, with a median duration of 23h 53m.

✈️ Airlines & availability

Connecting flights are dominant

This route is connecting-dominant, with a median of 3 stopovers on connecting flights.

🏆 Airline highlight

United Airlines offers a deal from $896

United Airlines has offered recent deals for this route, with a flight from $896.

🎯 Booking tip

Deals are rare for this route

Deals for flights from Guayaquil to Panama City are historically rare.

Guayaquil main airports to depart from

José Joaquín de Olmedo International (GYE)

Cheapest

José Joaquín de Olmedo International is a good option for flights from Guayaquil to Panama City.

📍 ~5 km from city center (reachable by car)

💸 Flights from ~$1,723

Panama City main airports to arrive at

Northwest Florida Beaches International (ECP)

Cheapest

Arrive at Northwest Florida Beaches International to access Panama City and surrounding areas.

📍 ~26 km from Panama City (reachable by car)

💸 Flights from ~$995

Airports nearby Panama City used as alternative

Destin–Fort Walton Beach (VPS)

Destin–Fort Walton Beach can be a useful alternative, serving the same general coastal region as Panama City.

📍 ~90 km from Panama City (traffic can be heavy during peak tourist seasons).

💸 Flights from ~$650

Business & First Class Flight Deals to Panama City

Discover luxury on the budget with premium cabin class on flights from Guayaquil to Panama City.

Elite

Best Elite deals to Panama City

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From GYE

Elite

Sep 02

Panama, Panama

38% AI deal score

$1,156

Frequently Asked Questions About Flights to Panama City

To find more affordable flights, consider being flexible with your travel dates and times. Using flight comparison sites can help you compare prices from various airlines and online travel agencies. Look out for deals and promotions that may be available for your desired route.

Booking in advance often provides more options and potentially better prices. However, last-minute deals can sometimes appear, so it's worth monitoring prices if your travel dates are flexible. Generally, booking a few months before your trip may offer a good balance.

Comparing nearby airports can sometimes uncover different flight options or prices. While it may add to your ground travel time, the potential savings could be significant. It's always a good idea to check if alternative airports in the region serve your destination.

Related routes

More routes from Guayaquil

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Flights to Panama City from other cities

Flights from Amsterdam to Panama City Flights from Frankfurt to Panama City Flights from Hong Kong to Panama City Flights from Medellín to Panama City Flights from Munich to Panama City Flights from Paris to Panama City Flights from Quito to Panama City Flights from Rome to Panama City Flights from San Juan to Panama City Flights from San Miguel de Tucumán to Panama City Flights from Santiago de Chile to Panama City

Guayaquil to Panama City: Overview

Insights for flights from Guayaquil to Panama City

How much is a round trip from Guayaquil to Panama City

Regular price: $518 - $1,391

Prices for flights from Guayaquil to Panama City are currently within the regular range.

The regular price range for this route is between $518 and $1391. The current lowest deal is $896 with United Airlines for travel from Feb 1-Feb 10.

now $896

Low $518

High $1,391

The cheapest time to fly from Guayaquil to Panama City

February

Cheapest

Flights from $1,027

October

Most Expensive

Flights from $1,831

Feb

Oct

Nov

Dec

Direct flights from Guayaquil to Panama City

WestJet

Avianca

Air Canada

United Airlines

Last-minute flights going from Guayaquil to Panama City

Mon, Oct 12

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$740

$5,777

One-way

Thu, Oct 22

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$489

$1,848

One-way

Mon, Oct 26

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$463

$1,626

One-way

Mon, Oct 26

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$473

$1,746

One-way

Mon, Oct 26

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$463

$1,948

One-way

Tue, Oct 27

⌛ Last-Minute

GYE - Panama City

Guayaquil (GYE) - Panama City (ECP)

Avianca, WestJet

$460

$1,626

One-way

Biggest price drops on these dates for flights from Guayaquil to Panama City

3 nights

Feb 6 - Feb 9

$668 → $1,027

54%

4 nights

Nov 26 - Nov 30

$521 → $1,156

122%

5 nights

Nov 18 - Nov 23

$516 → $1,624

214%

10 nights

Nov 13 - Nov 23

$479 → $1,624

239%

Popular Airports to fly from Guayaquil to Panama City