Are direct flights from Quito to Panama City always the best option?

Direct flights usually offer convenience and save travel time, but they are not always the most economical choice. Flights with layovers can sometimes be cheaper, depending on the route and airline. Consider your priorities for cost versus travel duration.

Can flexible travel dates help on Quito to Panama City flights?

Yes, being flexible with your travel dates can often lead to finding more affordable flights. Prices for airfare can vary significantly between different days of the week or even within the same week. Flying during off-peak days or seasons may result in lower fares.

What extra costs should I check before booking Quito to Panama City flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Understanding these additional expenses can help you calculate the total cost of your trip.

Flights From Quito

To Panama City

Cheap Flights from Quito to Panama City

Browse current best options from Quito. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Quito

RatePunk searches hundreds of travel sites at once for deals on flights to Panama City

Prices updated 2 days ago

405 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Jul 26, 2026.)

Today’s best flight deals from Quito to Panama City

Explore current cheapest deals departing from Quito to Panama City

2026-07-24 – 2026-07-31
UIO - Panama
71% AI deal score
$430
$323
Round trip
2026-09-01 – 2026-09-08
UIO - Panama
47% AI deal score
$356
$323
Round trip
2026-07-30 – 2026-08-03
UIO - Panama
39% AI deal score
$306
$334
Round trip
2026-07-31 – 2026-08-03
UIO - Panama
39% AI deal score
$307
$334
Round trip
2026-07-31 – 2026-08-04
UIO - Panama
39% AI deal score
$305
$334
Round trip
2026-07-31 – 2026-08-05
UIO - Panama
38% AI deal score
$292
$334
Round trip
2026-07-31 – 2026-08-12
UIO - Panama
38% AI deal score
$263
$334
Round trip
2026-08-01 – 2026-08-02
UIO - Panama
40% AI deal score
$279
$334
Round trip
2026-08-01 – 2026-08-05
UIO - Panama
40% AI deal score
$274
$334
Round trip
2026-08-01 – 2026-08-06
UIO - Panama
40% AI deal score
$260
$334
Round trip

Quito to Panama City: Overview

Insights for flights from Quito to Panama City

Right now, the cheapest flights from Quito to Panama City are priced significantly below the typical level. Fares for this route typically range from $824 to $1345, with a median price of $1024 over the last 90 days. However, none of the recent fares were classified as a good price.

If you are looking for the cheapest time to fly from Quito to Panama City, you will find that November is typically the most affordable month, with a median fare of $548. February also offers competitive prices, with a median of $553, followed closely by December at a median of $560.

Most itineraries for this route connect at least once, as 0% of recent fares were for non-stop flights. When connecting, the typical number of stopovers is 3, indicating that direct flights from Quito to Panama City are not common.

A typical journey from Quito to Panama City takes approximately 21h 47m, including connections. This duration reflects the prevalence of itineraries with multiple stopovers, as direct flights are not a significant part of the market for this route.

The distance between Quito and Panama City is 3480 kilometers, classifying this as a medium-haul flight. This distance typically involves a longer travel time, especially with connecting itineraries.

How much is a round trip from Quito to Panama City

Regular price: $344 - $426

Prices for flights from Quito to Panama are currently below the regular range.

The regular price range for flights from Quito to Panama is typically between $344 and $426. The current lowest deal is $323 on Kayak, for travel from Jul 28-Aug 1.

now $323

Low $344

High $426

The cheapest time to fly from Quito to Panama City

The cheapest month to fly from UIO to ECP is November, with a median price of $548. The most expensive month is April, with a median price of $1265. Prices are generally lower from January to December.

November

Cheapest

Flights from $548

April

Most Expensive

Flights from $1,265

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Quito to Panama City

Copa Airlines

Last-minute flights going from Quito to Panama City

Tue, Jul 28

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

United Airlines

$686

$1,448

One-way

Sat, Aug 1

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

United Airlines

$605

$1,230

One-way

Wed, Aug 5

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$261

$334

One-way

Thu, Aug 6

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$433

$324

One-way

Thu, Aug 6

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$430

$358

One-way

Fri, Aug 7

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$279

$334

One-way

Biggest price drops on these dates for flights from Quito to Panama City

3 nights

Aug 6 - Aug 9

$433 → $324

25%

4 nights

Aug 6 - Aug 10

$430 → $358

17%

4 nights

Aug 13 - Aug 17

$389 → $324

17%

2 nights

Aug 22 - Aug 24

$378 → $334

12%

Popular Airports to fly from Quito to Panama City

Quito - Panama City route insights

💸 Price insights

Recent fares are below the typical level

Recent fares from Quito to Panama City are below the typical level, with deals around $323.

📅 Best time to fly

November is historically cheapest

Historically, November is the cheapest month to fly from Quito to Panama City, with a median price of $548.

⏱️ Flight duration

Connecting flights average 21h 47m

Flights from Quito to Panama City typically take 21h 47m, with 3 stopovers common.

✈️ Airlines & availability

Connecting flights are dominant

Connecting flights are dominant on this route, with no direct flights available in recent data.

🏆 Airline highlight

Copa Airlines offers connecting flights

Copa Airlines offers connecting flights from Quito to Panama City, with deals available.

🎯 Booking tip

Deals appear regularly

Deals for flights from Quito to Panama City appear regularly, making it a good route for savings.

Quito main airports to depart from

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International Airport is a good option for flights from Quito to Panama City.

📍 ~15 km from Quito (reachable by car)

💸 Flights from ~$345

Panama City main airports to arrive at

Northwest Florida Beaches International (ECP)

Cheapest

Northwest Florida Beaches International Airport is a convenient arrival airport for Panama City.

📍 ~20 km from city center (reachable by car)

💸 Flights from ~$896

Airports nearby Panama City used as alternative

Destin–Fort Walton Beach (VPS)

Destin–Fort Walton Beach is a useful alternative arrival airport with frequent flight options.

📍 ~100 km from Panama City (traffic on Highway 98 can significantly impact travel time).

💸 Flights from ~$606

Business & First Class Flight Deals to Panama City

Discover luxury on the budget with premium cabin class on flights from Quito to Panama City.

Panama City, United States

66% AI deal score

$5,222

Frequently Asked Questions About Flights to Panama City

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking platforms can often reveal better deals. Setting up price alerts may also help you catch drops in fares.

Booking in advance, often several months before your intended travel date, can sometimes result in lower prices. However, last-minute deals can occasionally appear, so it may be beneficial to monitor prices if your schedule allows for flexibility. Mid-week bookings are also sometimes associated with better fares.

Comparing flights to and from nearby airports can sometimes offer more options or different prices. While it may add to your ground travel, the potential savings on airfare could be significant. Always factor in the cost and time of additional transportation.

Related routes

More routes from Quito

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Flights to Panama City from other cities

Flights from Amsterdam to Panama City Flights from Barcelona to Panama City Flights from Bogotá to Panama City Flights from Frankfurt to Panama City Flights from Guayaquil to Panama City Flights from Hong Kong to Panama City Flights from Lisbon to Panama City Flights from Madrid to Panama City Flights from Medellín to Panama City Flights from Munich to Panama City Flights from Paris to Panama City Flights from Reykjavik to Panama City

Quito to Panama City: Overview

Insights for flights from Quito to Panama City

How much is a round trip from Quito to Panama City

Regular price: $344 - $426

Prices for flights from Quito to Panama are currently below the regular range.

The regular price range for flights from Quito to Panama is typically between $344 and $426. The current lowest deal is $323 on Kayak, for travel from Jul 28-Aug 1.

now $323

Low $344

High $426

The cheapest time to fly from Quito to Panama City

November

Cheapest

Flights from $548

April

Most Expensive

Flights from $1,265

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec