Are direct flights from Quito to Panama City always the best option?

Direct flights offer convenience and save time, but they are not always the most budget-friendly choice. Flights with layovers can often be cheaper, though they will extend your travel duration. Your preference for convenience versus cost will determine the best option for your trip.

Can flexible travel dates help on Quito to Panama City flights?

Yes, being flexible with your travel dates can significantly impact flight prices. Flying on weekdays or during off-peak seasons often results in lower fares compared to weekends or holidays. Adjusting your departure or return by a few days may reveal more affordable options.

What extra costs should I check before booking Quito to Panama City flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may charge for carry-on bags or checked luggage, which can add to the total price. Understanding these fees beforehand helps avoid surprises.

Flights From Quito

To Panama City

Cheap Flights from Quito to Panama City

Browse current best options from Quito. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Quito

RatePunk searches hundreds of travel sites at once for deals on flights to Panama City

Prices updated 7 days ago

482 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Oct 26, 2026.)

Today’s best flight deals from Quito to Panama City

Explore current cheapest deals departing from Quito to Panama City

2026-11-01 – 2026-11-10
UIO - Panama City
40% AI deal score
$560
$1,489
Round trip
2026-12-07 – 2027-01-06
UIO - Panama City
39% AI deal score
$512
$1,739
Round trip
2026-12-28 – 2027-01-06
UIO - Panama City
39% AI deal score
$578
$1,742
Round trip
2026-12-17 – 2027-01-06
UIO - Panama City
39% AI deal score
$518
$1,802
Round trip
2026-12-23 – 2027-01-06
UIO - Panama City
39% AI deal score
$550
$1,831
Round trip
2026-12-20 – 2027-01-06
UIO - Panama City
39% AI deal score
$531
$1,834
Round trip
2026-12-21 – 2027-01-06
UIO - Panama City
39% AI deal score
$538
$1,835
Round trip
2026-12-29 – 2027-01-06
UIO - Panama City
39% AI deal score
$579
$1,841
Round trip
2026-11-11 – 2026-11-14
UIO - Panama City
39% AI deal score
$552
$1,899
Round trip
2026-11-09 – 2026-11-14
UIO - Panama City
39% AI deal score
$546
$1,901
Round trip

Quito to Panama City: Overview

Insights for flights from Quito to Panama City

Right now, the cheapest flights from Quito to Panama City typically range from $824 to $1345, with a median fare of $1024. Current fares are below the typical level for this route. New deals for this route are infrequent, so setting up a price alert can be beneficial to catch the best offers.

For travelers wondering when is the cheapest time to fly from Quito to Panama City, the data indicates that November is typically the most affordable month, with a median fare of $548. Following closely are February, with a median of $553, and December, where the median fare is $560.

When flying from Quito to Panama City, most itineraries connect at least once, as direct flights make up 0% of recent fares. For connecting itineraries, the typical number of stopovers is 3.

A typical journey from Quito to Panama City takes approximately 21h 47m, including connections. This duration accounts for itineraries with one or more stops, which are common on this route.

The distance between Quito and Panama City is 3480 kilometers, classifying this as a medium-haul route. This distance typically involves a longer travel time and often includes connecting flights.

How much is a round trip from Quito to Panama City

Regular price: $475 - $640

Prices for flights from Quito to Panama City are currently above the regular range.

The regular price range for this route is typically between $475 and $640. The current lowest deal is $1489 with United Airlines, for travel from Nov 1-Nov 10.

now $1,489

Low $475

High $640

The cheapest time to fly from Quito to Panama City

The cheapest month to fly from UIO to ECP is February, with a median price of $710. The most expensive month is December, with a median price of $1916. Prices are generally lower from February to November.

February

Cheapest

Flights from $710

December

Most Expensive

Flights from $1,916

Feb

Oct

Nov

Dec

Direct flights from Quito to Panama City

WestJet

Avianca

United Airlines

Copa Airlines

Last-minute flights going from Quito to Panama City

Sat, Nov 7

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

Avianca, WestJet

$487

$2,047

One-way

Mon, Nov 9

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

Copa Airlines, WestJet

$473

$1,981

One-way

Tue, Nov 10

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

Avianca, WestJet

$460

$1,974

One-way

Thu, Nov 12

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

Avianca, WestJet

$453

$1,972

One-way

Sat, Nov 14

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

LATAM Chile, Air Canada, WestJet

$456

$1,952

One-way

Tue, Nov 17

⌛ Last-Minute

UIO - Panama City

Quito (UIO) - Panama City (ECP)

Avianca, WestJet

$456

$1,974

One-way

Biggest price drops on these dates for flights from Quito to Panama City

21 nights

Dec 16 - Jan 6

$518 → $1,735

235%

23 nights

Dec 14 - Jan 6

$518 → $1,736

235%

30 nights

Dec 17 - Jan 16

$512 → $1,737

239%

30 nights

Dec 7 - Jan 6

$508 → $1,737

242%

Popular Airports to fly from Quito to Panama City

Quito - Panama City route insights

💸 Price insights

Recent fares are above the typical level.

Recent fares for flights from Quito to Panama City are above the typical level.

📅 Best time to fly

November, February, and December are historically cheapest.

Historically, November ($548), February ($553), and December ($560) offer the lowest median prices.

⏱️ Flight duration

Connecting flights typically take 21h 47m.

Flights from Quito to Panama City typically involve connections, with a median duration of 21h 47m.

✈️ Airlines & availability

Connecting flights are dominant on this route.

This route is dominated by connecting flights, with a median of 3 stopovers.

🏆 Airline highlight

WestJet offers 22 direct deals.

WestJet has 22 direct deals, followed by Avianca with 18 direct deals.

🎯 Booking tip

Deals are rare for this route.

Deals for flights from Quito to Panama City are rare, appearing infrequently.

Quito main airports to depart from

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International is a convenient option for flights from Quito to Panama City.

📍 ~14 km from city center (reachable by car)

💸 Flights from ~$700

Panama City main airports to arrive at

Northwest Florida Beaches International (ECP)

Cheapest

Northwest Florida Beaches International Airport is a good arrival choice for Panama City.

📍 ~26 km from Panama City (reachable by car)

💸 Flights from ~$730

Airports nearby Panama City used as alternative

Destin–Fort Walton Beach (VPS)

Destin–Fort Walton Beach is a useful alternative arrival airport, serving the same general coastal region.

📍 ~90 km from Panama City (reachable by car, though traffic can be heavy).

💸 Flights from ~$723

Business & First Class Flight Deals to Panama City

Discover luxury on the budget with premium cabin class on flights from Quito to Panama City.

Elite

Best Elite deals to Panama City

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From UIO

Elite

Oct 24

Panama City, United States

68% AI deal score

$4,067

LATAM Chile, +1

Business Class

From UIO

Elite

Oct 25

Panama City, United States

68% AI deal score

$4,190

LATAM Chile, +1

Business Class

From UIO

Elite

Nov 12

Panama City, United States

66% AI deal score

$4,631

LATAM Chile, +1

Business Class

From UIO

Elite

Oct 29

Panama, Panama

40% AI deal score

$980

Frequently Asked Questions About Flights to Panama City

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you discover better deals. Looking into flights with layovers may sometimes offer lower fares than direct routes.

Booking flights in advance, often several weeks or months before your intended travel date, can sometimes result in lower prices. Prices may fluctuate, so monitoring fares over time can help you identify a good booking window. Avoiding peak travel seasons can also lead to more economical options.

Comparing nearby airports at both your origin and destination can sometimes uncover alternative flight options or better prices. While it may add to your travel time, the potential savings could be significant. Always consider the total cost and convenience when evaluating this option.

Related routes

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Flights to Panama City from other cities

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Quito to Panama City: Overview

Insights for flights from Quito to Panama City

When flying from Quito to Panama City, most itineraries connect at least once, as direct flights make up 0% of recent fares. For connecting itineraries, the typical number of stopovers is 3.

A typical journey from Quito to Panama City takes approximately 21h 47m, including connections. This duration accounts for itineraries with one or more stops, which are common on this route.

How much is a round trip from Quito to Panama City

Regular price: $475 - $640

Prices for flights from Quito to Panama City are currently above the regular range.

The regular price range for this route is typically between $475 and $640. The current lowest deal is $1489 with United Airlines, for travel from Nov 1-Nov 10.

now $1,489

Low $475

High $640

The cheapest time to fly from Quito to Panama City

February

Cheapest

Flights from $710

December

Most Expensive

Flights from $1,916

Feb

Oct

Nov

Dec