Are direct flights from Quito to Panama City always the best option?

Direct flights offer convenience by reducing travel time and avoiding layovers. However, they are not always the cheapest option. Flights with connections can sometimes be more affordable, so it's worth comparing both types of itineraries.

Can flexible travel dates help on Quito to Panama City flights?

Yes, being flexible with your travel dates can often lead to finding cheaper flights. Prices can vary significantly depending on the day of the week or season. Adjusting your departure or return by a few days may result in notable savings.

What extra costs should I check before booking Quito to Panama City flights?

Before booking, always check for potential extra costs such as baggage fees, seat selection charges, and in-flight services. Some airlines may also charge for printing boarding passes at the airport. Being aware of these additional fees can help you budget accurately.

Flights From Quito

To Panama City

Cheap Flights from Quito to Panama City

Browse current best options from Quito. Become a member to unlock all deals and get alerts when new deals appear.

Deals from

Quito

RatePunk searches hundreds of travel sites at once for deals on flights to Panama City

Prices updated 2 days ago

461 airlines compared

80%+ AI score for best value

Fares are subject to change and may not be available for all dates. (Data last updated Sep 14, 2026.)

Today’s best flight deals from Quito to Panama City

Explore current cheapest deals departing from Quito to Panama City

2026-09-19 – 2026-09-21
UIO - Panama
76% AI deal score
$525
$316
Round trip
2026-09-30 – 2026-10-04
UIO - Panama
50% AI deal score
$390
$327
Round trip
2027-02-20 – 2027-03-07
UIO - Panama
41% AI deal score
$309
$327
Round trip
2026-09-19 – 2026-09-26
UIO - Panama
41% AI deal score
$286
$346
Round trip
2026-09-19 – 2026-09-27
UIO - Panama
40% AI deal score
$266
$346
Round trip
2026-09-20 – 2026-09-22
UIO - Panama
42% AI deal score
$325
$346
Round trip
2026-09-21 – 2026-09-27
UIO - Panama
40% AI deal score
$276
$346
Round trip
2026-09-21 – 2026-10-05
UIO - Panama
40% AI deal score
$243
$346
Round trip
2026-09-22 – 2026-09-27
UIO - Panama
40% AI deal score
$279
$346
Round trip
2026-09-23 – 2026-09-30
UIO - Panama
40% AI deal score
$259
$346
Round trip

Quito to Panama City: Overview

Insights for flights from Quito to Panama City

Right now, fares for cheap flights from Quito to Panama City are significantly below the typical level. Prices for this route typically range from $824 to $1345, with a median of $1024 over the last 90 days. Currently, 0% of recent fares are classified as a good price, indicating that while current prices are low, finding what is considered a 'good deal' has been uncommon.

If you are looking for the cheapest time to fly from Quito to Panama City, the data indicates that November is typically the most affordable month, with a median fare of $548. Following closely, February also offers competitive prices, with a median fare of $553. December is another relatively inexpensive option, with a median fare of $560, making these months the best for finding lower prices.

For flights from Quito to Panama City, most itineraries connect at least once, with 0% of recent fares being non-stop. When connections are necessary, the typical number of stopovers is 3. This suggests that travelers should anticipate at least one stop on their journey.

A typical journey from Quito to Panama City takes approximately 21h 47m, including connections. This duration accounts for the fact that most itineraries involve at least one stopover, reflecting the overall travel time for this route.

The distance between Quito and Panama City is 3480 km, classifying this route as a medium-haul flight. This distance typically involves a longer travel time, often with connecting flights, rather than a short, direct hop.

How much is a round trip from Quito to Panama City

Regular price: $434 - $569

Prices for flights from Quito to Panama are currently below the regular range.

The regular price range for flights from Quito to Panama is USD 434 to USD 569. The current lowest deal is USD 315 on Kayak for travel from Sep 18-Sep 21.

now $315

Low $434

High $569

The cheapest time to fly from Quito to Panama City

The cheapest month to fly from UIO to ECP is November, with a median price of $548. The most expensive month is April, with a median price of $1265. Prices are generally lower from January to December.

November

Cheapest

Flights from $548

April

Most Expensive

Flights from $1,265

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Direct flights from Quito to Panama City

Copa Airlines

Last-minute flights going from Quito to Panama City

Sat, Sep 19

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$525

$316

One-way

Sat, Sep 19

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$286

$346

One-way

Sat, Sep 19

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$266

$346

One-way

Sun, Sep 20

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$325

$346

One-way

Mon, Sep 21

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$276

$346

One-way

Mon, Sep 21

⌛ Last-Minute

UIO - Panama

Quito (UIO) - Panama (PTY)

$243

$346

One-way

Biggest price drops on these dates for flights from Quito to Panama City

3 nights

Sep 18 - Sep 21

$519 → $315

39%

2 nights

Sep 19 - Sep 21

$497 → $316

36%

3 nights

Sep 24 - Sep 27

$426 → $329

23%

2 nights

Sep 25 - Sep 27

$427 → $346

19%

Popular Airports to fly from Quito to Panama City

Quito - Panama City route insights

💸 Price insights

Recent fares are below the typical level.

Recent fares from Quito to Panama City are below the typical level, with a median price of $1024.

📅 Best time to fly

Fly in November for the best prices.

Historically, November ($548), February ($553), and December ($560) offer the lowest median prices.

⏱️ Flight duration

Flights typically last 21h 47m.

The median flight duration from Quito to Panama City is 21 hours and 47 minutes.

✈️ Airlines & availability

Connecting flights are dominant.

Connecting flights are dominant for this route, with a median of 3 stopovers.

🏆 Airline highlight

Copa Airlines offers direct deals.

Copa Airlines has offered direct deals on this route, providing a convenient travel option.

🎯 Booking tip

Deals appear regularly.

Historically, deals for flights on this route appear regularly, typically within a 30-day window.

Quito main airports to depart from

Mariscal Sucre International (UIO)

Cheapest

Mariscal Sucre International is a good option for flights from Quito to Panama City.

📍 ~14 km from Quito (reachable by car)

💸 Flights from ~$314

Panama City main airports to arrive at

Northwest Florida Beaches International (ECP)

Cheapest

Northwest Florida Beaches International Airport is a good option for travelers seeking flights to Panama City.

📍 ~26 km from Panama City (reachable by car)

💸 Flights from ~$932

Airports nearby Panama City used as alternative

Destin–Fort Walton Beach (VPS)

Destin–Fort Walton Beach is a useful alternative for its proximity and similar service to the region.

📍 ~90 km from Panama City (traffic can be heavy during peak tourist seasons).

💸 Flights from ~$626

Business & First Class Flight Deals to Panama City

Discover luxury on the budget with premium cabin class on flights from Quito to Panama City.

Elite

Best Elite deals to Panama City

Exclusive daily First Class, Business Class, and Premium Economy flight deals, refreshed every 24 hours.

From UIO

Elite

Oct 26

Panama City, United States

67% AI deal score

$4,560

Aeroméxico, +1

Business Class

From UIO

Elite

Nov 05

Panama City, United States

67% AI deal score

$4,599

Aeroméxico, +1

Business Class

From UIO

Elite

Oct 27

Panama City, United States

67% AI deal score

$4,602

Aeroméxico, +1

Business Class

From UIO

Elite

Oct 19

Panama City, United States

66% AI deal score

$4,973

Aeroméxico, +1

Business Class

Frequently Asked Questions About Flights to Panama City

To find more affordable flights, consider being flexible with your travel dates and times. Comparing prices across different airlines and booking sites can also help you discover better deals. Often, setting up price alerts can notify you when fares drop for your desired route.

Booking in advance is often recommended, as prices may increase closer to the departure date. However, sometimes last-minute deals can appear. It's usually beneficial to monitor fare trends to identify the optimal booking window for your trip.

Comparing nearby airports can sometimes reveal more economical flight options or different schedules. While it may add to your travel time, the potential savings could be significant. Always check ground transportation costs and convenience if considering alternative airports.

Related routes

More routes from Quito

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Flights to Panama City from other cities

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Quito to Panama City: Overview

Insights for flights from Quito to Panama City

How much is a round trip from Quito to Panama City

Regular price: $434 - $569

Prices for flights from Quito to Panama are currently below the regular range.

The regular price range for flights from Quito to Panama is USD 434 to USD 569. The current lowest deal is USD 315 on Kayak for travel from Sep 18-Sep 21.

now $315

Low $434

High $569

The cheapest time to fly from Quito to Panama City

November

Cheapest

Flights from $548

April

Most Expensive

Flights from $1,265

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec